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ONTOLOGY REPORT - ANNOTATIONS


Term:neutral lipid biosynthetic process
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Accession:GO:0046460 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.
Synonyms:exact_synonym: neutral lipid anabolism;   neutral lipid biosynthesis;   neutral lipid formation;   neutral lipid synthesis



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diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin involved_in ISO (PMID:2457905) RGD PMID:2457905 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5465510|PMID:23066022)
UniProt
RGD
PMID:23066022 GO_REF:0000024 MGI:5465510 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in IMP PMID:22905194 UniProt PMID:22905194 RGD:30309909 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2181469|PMID:12077311)
RGD PMID:12077311 PMID:21873635 MGI:2181469, RGD:13792537 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2656067|PMID:12576479), (MGI:3040558|PMID:14966132)
RGD PMID:12576479 PMID:14966132 PMID:21873635 MGI:2656067 MGI:3040558, RGD:13792537 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISS
ISO
GO_REF:0000024
(MGI:6392937|PMID:17626977)
UniProt
RGD
PMID:17626977 GO_REF:0000024 MGI:6392937 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29058690)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5465510|PMID:23066022)
UniProt
RGD
PMID:23066022 GO_REF:0000024 MGI:5465510 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
PMID:21873635
MGI:2182390 (MGI:2157262|PMID:11792850)
PMID:4186849
RGD PMID:11792850 PMID:21873635 PMID:4186849 MGI:2157262, RGD:13792537, RGD:8553288 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
monoacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Awat2 acyl-CoA wax alcohol acyltransferase 2 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:65,482,240...65,490,500
Ensembl chr  X:65,481,929...65,527,625
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5906070|PMID:28420705)
(PMID:28420705)
UniProt
RGD
PMID:28420705 GO_REF:0000024 MGI:5906070 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISO
ISS
(PMID:28420705)
GO_REF:0000024
RGD
UniProt
PMID:28420705 GO_REF:0000024 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgat2l6 diacylglycerol O-acyltransferase 2-like 6 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr  X:65,614,430...65,637,962
Ensembl chr  X:65,614,430...65,637,962
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in ISO (PMID:28420705) RGD PMID:28420705 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
ISS
(PMID:7794891)
GO_REF:0000024
RGD
UniProt
PMID:7794891 GO_REF:0000024 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir30c1 microRNA 30c-1 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir30c2 microRNA 30c-2 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IMP RGD PMID:29148806 RGD:15042869 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294536|PMID:19244231)
UniProt
RGD
PMID:19244231 GO_REF:0000024 MGI:5294536 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:29765047) RGD PMID:29765047 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 IDA RGD PMID:16263710 RGD:2312807 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Apoc3 apolipoprotein C3 IMP RGD PMID:23542898 RGD:10054091 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in ISO (PMID:22134922) RGD PMID:22134922 NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 involved_in ISO
ISS
(PMID:22134922)
GO_REF:0000024
RGD
UniProt
PMID:22134922 GO_REF:0000024 NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:23449193 RGD:10400846 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IDA RGD PMID:15598672 RGD:2313665 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3617276|PMID:16219662)
UniProt
RGD
PMID:16219662 GO_REF:0000024 MGI:3617276 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:29765047)
UniProt
RGD
PMID:29765047 GO_REF:0000024 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17693624)
GO_REF:0000107
RGD
Ensembl
PMID:17693624 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:3709110|PMID:17130488), (MGI:5440401|PMID:22532565), (MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:17130488 PMID:21885430 PMID:22532565 GO_REF:0000024 MGI:3709110 MGI:5440401 MGI:5559666 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6154651|PMID:12235169)
UniProt
RGD
PMID:12235169 GO_REF:0000024 MGI:6154651 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2177959 (MGI:3603730|PMID:16046411)
(MGI:5294536|PMID:19244231)
UniProt
RGD
PMID:16046411 PMID:19244231 GO_REF:0000024 MGI:3603730 MGI:5294536 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:5468191|PMID:23260145) RGD PMID:23260145 MGI:5468191 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
regulation of diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avil advillin involved_in ISS
ISO
GO_REF:0000024
(PMID:29058690)
UniProt
RGD
PMID:29058690 GO_REF:0000024 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10432298)
Ensembl
UniProt
RGD
PMID:10432298 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772596|PMID:18160536)
UniProt
RGD
PMID:18160536 GO_REF:0000024 MGI:3772596 NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858
JBrowse link
G Thrsp thyroid hormone responsive involved_in IEA
ISO
GO_REF:0000107
(MGI:3769289|PMID:15890771)
Ensembl
RGD
PMID:15890771 GO_REF:0000107 MGI:3769289 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 IGI RGD PMID:16466685 RGD:2312800 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IGI RGD PMID:16466685 RGD:2312800 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Agmo alkylglycerol monooxygenase involved_in ISO (MGI:7294179|PMID:35537527) RGD PMID:35537527 MGI:7294179 NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in ISO MGI:1915643 (MGI:3838087|PMID:19187773), (MGI:7439753|PMID:16495223) RGD PMID:16495223 PMID:19187773 MGI:3838087 MGI:7439753 NCBI chr 3:9,416,842...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
IBA
GO_REF:0000002
(PMID:18458083)
(PMID:18238778), (PMID:32433610), (PMID:32433611)
(MGI:1855734|PMID:10802663), (MGI:2151970|PMID:11481335), (MGI:3036977|PMID:14668353)
PMID:21873635
InterPro
RGD
PMID:10802663 PMID:11481335 PMID:14668353 PMID:18238778 PMID:18458083 More... GO_REF:0000002 MGI:1855734 MGI:2151970 MGI:3036977, RGD:1625586, RGD:13792537 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:11481335), (PMID:27184406)
(MGI:5293272|PMID:21680734)
PMID:21873635
MGI:3037903 (MGI:2151970|PMID:11481335), (MGI:2181469|PMID:12077311), (MGI:3036977|PMID:14668353)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:11481335 PMID:12077311 PMID:14668353 PMID:21680734 PMID:27184406 More... GO_REF:0000024 GO_REF:0000041 MGI:2151970 MGI:2181469 MGI:3036977 MGI:5293272, RGD:13792537 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Gk glycerol kinase involved_in ISO
IEA
MGI:2429928 (MGI:1097749|PMID:9302256)
GO_REF:0000107
RGD
Ensembl
PMID:9302256 GO_REF:0000107 MGI:1097749 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in IEA
ISO
GO_REF:0000107
MGI:2669956 (MGI:2668268|PMID:12417724), (MGI:5527209|PMID:23908354)
(PMID:18238778)
Ensembl
RGD
PMID:12417724 PMID:18238778 PMID:23908354 GO_REF:0000107 MGI:2668268 MGI:5527209 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial acts_upstream_of_or_within ISO (MGI:3762297|PMID:17689486) RGD PMID:17689486 MGI:3762297 NCBI chr 3:114,646,446...114,657,051
Ensembl chr 3:114,648,498...114,657,051
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 involved_in ISO
ISS
IEA
(PMID:17170135)
GO_REF:0000024
(MGI:3699028|PMID:17170135)
GO_REF:0000041
RGD
UniProt
PMID:17170135 GO_REF:0000024 GO_REF:0000041 MGI:3699028 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 NOT|involved_in ISO (PMID:18238778)
(MGI:3623703|PMID:16436371)
RGD PMID:16436371 PMID:18238778 MGI:3623703 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (MGI:6467683|PMID:20018982) RGD PMID:20018982 MGI:6467683 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lpin1 lipin 1 involved_in ISO
IBA
(PMID:29765047)
(MGI:5566973|PMID:24133206)
PMID:21873635
RGD PMID:24133206 PMID:29765047 PMID:21873635 MGI:5566973, RGD:13792537 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpin2 lipin 2 involved_in IBA
ISO
PMID:21873635
(MGI:3844413|PMID:19136718)
RGD PMID:19136718 PMID:21873635 MGI:3844413, RGD:13792537 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Lpin3 lipin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Lpl lipoprotein lipase IMP RGD PMID:11788374 RGD:70246 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2656067|PMID:12576479)
(MGI:3040558|PMID:14966132)
PMID:21873635
RGD PMID:12576479 PMID:14966132 PMID:21873635 MGI:2656067 MGI:3040558, RGD:13792537 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in ISO
IBA
(PMID:27184406)
PMID:21873635
RGD PMID:27184406 PMID:21873635 RGD:13792537 NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 involved_in ISO (PMID:15364929), (PMID:22560221)
(MGI:5426312|PMID:22560221)
RGD PMID:15364929 PMID:22560221 MGI:5426312 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular biosynthetic process 2909
          neutral lipid biosynthetic process 55
            acylglycerol biosynthetic process + 55
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      primary metabolic process 8886
        lipid metabolic process 1448
          cellular lipid metabolic process 1051
            neutral lipid metabolic process 148
              neutral lipid biosynthetic process 55
                acylglycerol biosynthetic process + 55
paths to the root