Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:aflatoxin catabolic process
go back to main search page
Accession:GO:0046223 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms:exact_synonym: aflatoxin breakdown;   aflatoxin catabolism;   aflatoxin degradation


show annotations for term's descendants           Sort by:
 
aflatoxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr7a3 aldo-keto reductase family 7 member A3 IMP RGD PMID:12727802 RGD:1304380 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 acts_upstream_of_or_within ISO MGI:4430389 (MGI:4429761|PMID:19850059) RGD PMID:19850059 MGI:4429761 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IMP RGD PMID:27071940 RGD:12910550 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    detoxification 137
      toxin catabolic process 3
        mycotoxin catabolic process 3
          aflatoxin catabolic process 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    response to stimulus 10358
      response to chemical 6187
        response to toxic substance 307
          detoxification 137
            toxin catabolic process 3
              mycotoxin catabolic process 3
                aflatoxin catabolic process 3
paths to the root