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ONTOLOGY REPORT - ANNOTATIONS


Term:tetrahydrobiopterin metabolic process
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Accession:GO:0046146 term browser browse the term
Definition:The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
Synonyms:exact_synonym: 5,6,7,8-tetrahydrobiopterin metabolic process;   tetrahydrobiopterin metabolism


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tetrahydrobiopterin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPR sepiapterin reductase acts_upstream_of_or_within ISO (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chr 3:69,889,448...69,894,747
Ensembl chr 3:69,887,386...69,894,758
JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:184,201,232...184,264,060
Ensembl chr 1:184,202,007...184,257,315
JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:73,769,339...73,807,278
Ensembl chr14:73,772,835...73,807,281
JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1328867|PMID:9894812) UniProt
MGI
PMID:9894812 GO_REF:0000041 MGI:1328867 NCBI chr 9:39,920,157...39,927,804
Ensembl chr 9:39,920,273...39,928,634
JBrowse link
G QDPR quinoid dihydropteridine reductase involved_in IBA
ISO
ISS
(PMID:21873635) GO_Central
RGD
UniProt
PMID:660556 PMID:9235988 PMID:21873635 GO_REF:0000024 RGD:4139903 RGD:5128582 NCBI chr 8:12,529,500...12,549,471
Ensembl chr 8:12,335,252...12,549,603
JBrowse link
G SPR sepiapterin reductase involved_in IBA
ISO
IEA
(PMID:21873635) GO_Central
RGD
InterPro
PMID:2179471 PMID:21873635 GO_REF:0000002 RGD:1600056 NCBI chr 3:69,889,448...69,894,747
Ensembl chr 3:69,887,386...69,894,758
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10419
      cellular metabolic process 9472
        heterocycle metabolic process 5044
          pteridine-containing compound metabolic process 32
            tetrahydrobiopterin metabolic process 6
              tetrahydrobiopterin biosynthetic process 6
              tetrahydrobiopterin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10419
      organic substance metabolic process 9984
        organic hydroxy compound metabolic process 498
          alcohol metabolic process 323
            polyol metabolic process 113
              diol metabolic process 26
                tetrahydrobiopterin metabolic process 6
                  tetrahydrobiopterin biosynthetic process 6
                  tetrahydrobiopterin catabolic process 0
paths to the root