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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleobase biosynthetic process
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Accession:GO:0046112 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
Synonyms:exact_synonym: nucleobase anabolism;   nucleobase biosynthesis;   nucleobase formation;   nucleobase synthesis


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'de novo' pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IDA
IBA
ISO		 GO_REF:0000033
(PMID:24332717)		 GO_Central
RGD		 PMID:24332717 PMID:1476792 GO_REF:0000033, RGD:5132591 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Dhodh dihydroorotate dehydrogenase involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro
RGD		 PMID:1476792 GO_REF:0000002 GO_REF:0000033, RGD:5132591 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:23429704)		 Ensembl
RGD		 PMID:23429704 GO_REF:0000107 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
adenine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aprt adenine phosphoribosyl transferase involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431 		JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IBA
IEA
ISS		 (PMID:19527031)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:19527031 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Prtfdc1 phosphoribosyl transferase domain containing 1 NOT|involved_in ISO (PMID:21054786) RGD PMID:21054786 NCBI chr17:83,549,608...83,654,517
Ensembl chr17:83,548,803...83,655,179 		JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857117|MGI:2683027 (PMID:10720488)
GO_REF:0000107		 RGD
Ensembl		 PMID:10720488 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (PMID:17701896) RGD PMID:17701896 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187 		JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA
ISS		 (PMID:19527031)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19527031 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase involved_in ISS
ISO		 GO_REF:0000024
(PMID:31600779)		 UniProt
RGD		 PMID:31600779 GO_REF:0000024 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11516159) RGD PMID:11516159 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctps1 CTP synthase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:10720488)		 Ensembl
RGD		 PMID:10720488 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19526
      metabolic process 12168
        biosynthetic process 8660
          nucleobase biosynthetic process 17
            purine nucleobase biosynthetic process + 9
            pyrimidine nucleobase biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19526
      metabolic process 12168
        primary metabolic process 10755
          nucleobase-containing compound metabolic process 5944
            nucleobase-containing small molecule metabolic process 729
              nucleobase metabolic process 45
                nucleobase biosynthetic process 17
                  purine nucleobase biosynthetic process + 9
                  pyrimidine nucleobase biosynthetic process + 8
paths to the root