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ONTOLOGY REPORT - ANNOTATIONS

Term:cGMP metabolic process
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Accession:GO:0046068 term browser browse the term
Definition:The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
Synonyms:exact_synonym: cGMP metabolism

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cGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (PMID:3038581), (PMID:7518067) MGI PMID:3038581 PMID:7518067 NCBI chrNW_004936602:2,744,757...3,011,051
Ensembl chrNW_004936602:2,744,759...3,007,940 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:3,779,398...3,798,074
Ensembl chrNW_004936524:3,779,392...3,798,501 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19474061), (PMID:20511540) Ensembl
MGI		 PMID:19474061 PMID:20511540 GO_REF:0000107 NCBI chrNW_004936869:24,265...117,120
Ensembl chrNW_004936869:39,122...117,127 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:1,201,843...1,266,818
Ensembl chrNW_004936500:1,203,437...1,267,095 		JBrowse link
G Rora RAR related orphan receptor A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7518067) Ensembl
MGI		 PMID:7518067 GO_REF:0000107 NCBI chrNW_004936471:21,402,056...21,567,908
Ensembl chrNW_004936471:21,400,589...22,069,643 		JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16614755) InterPro
MGI
Ensembl		 PMID:16614755 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936576:2,353,874...2,411,747
Ensembl chrNW_004936576:2,353,761...2,411,425 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936551:1,573,930...1,814,685
Ensembl chrNW_004936551:1,575,356...1,814,697 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936576:2,427,451...2,469,946
Ensembl chrNW_004936576:2,427,416...2,470,072 		JBrowse link
G Gucy2c guanylate cyclase 2C involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004936587:2,742,911...2,811,139
Ensembl chrNW_004936587:2,742,911...2,810,969 		JBrowse link
G Gucy2d guanylate cyclase 2D, retinal involved_in IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chrNW_004936595:1,235,747...1,250,294
Ensembl chrNW_004936595:1,235,711...1,250,354 		JBrowse link
G LOC101964576 guanylate cyclase soluble subunit beta-2-like involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936565:3,877,047...3,930,198 JBrowse link
G Nppa natriuretic peptide A acts_upstream_of
involved_in		 ISO
IEA		 (PMID:1672777) GO_Central
TreeGrafter
RGD		 PMID:1672777 PMID:10559136 GO_REF:0000118 RGD:619660 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Nppb natriuretic peptide B acts_upstream_of
involved_in		 ISO
IEA		 (PMID:1672777) GO_Central
TreeGrafter
Ensembl		 PMID:1672777 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:683,325...684,662
Ensembl chrNW_004936474:683,325...684,665 		JBrowse link
G Nppc natriuretic peptide C acts_upstream_of
involved_in		 ISO
IEA		 (PMID:1672777)
(MGI:2177134|PMID:11259675)		 GO_Central
TreeGrafter
Ensembl		 PMID:1672777 PMID:11259675 GO_REF:0000107 GO_REF:0000118 MGI:2177134 NCBI chrNW_004936525:5,092,675...5,099,344
Ensembl chrNW_004936525:5,092,635...5,099,331 		JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2179542|PMID:11997476) Ensembl
GOC
UniProt		 PMID:11997476 GO_REF:0000043 GO_REF:0000107 MGI:2179542 NCBI chrNW_004936580:3,479,858...3,496,896
Ensembl chrNW_004936580:3,480,267...3,495,643 		JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of
acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:1672777)
(MGI:2682104|PMID:14514678)		 GO_Central
GOC
Ensembl
UniProt		 PMID:1672777 PMID:14514678 GO_REF:0000043 GO_REF:0000107 MGI:2682104 NCBI chrNW_004936524:3,779,398...3,798,074
Ensembl chrNW_004936524:3,779,392...3,798,501 		JBrowse link
cGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde1a phosphodiesterase 1A ISO RGD PMID:16514069 RGD:2312521 NCBI chrNW_004936509:10,819,067...11,142,964
Ensembl chrNW_004936509:10,818,912...11,142,501 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:1,856,256...1,944,405
Ensembl chrNW_004936498:1,856,144...1,944,412 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12554648) Ensembl
MGI		 PMID:12554648 GO_REF:0000107 NCBI chrNW_004936869:24,265...117,120
Ensembl chrNW_004936869:39,122...117,127 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936500:1,201,843...1,266,818
Ensembl chrNW_004936500:1,203,437...1,267,095 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    metabolic process 9527
      cellular metabolic process 8291
        cellular aromatic compound metabolic process 4861
          purine-containing compound metabolic process 490
            purine nucleotide metabolic process 458
              purine ribonucleotide metabolic process 381
                cGMP metabolic process 17
                  cGMP biosynthetic process 11
                  cGMP catabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 15871
    metabolic process 9527
      organic substance metabolic process 9091
        organic cyclic compound metabolic process 5090
          nucleobase-containing compound metabolic process 4641
            nucleobase-containing small molecule metabolic process 579
              nucleoside phosphate metabolic process 520
                nucleotide metabolic process 514
                  ribonucleotide metabolic process 402
                    purine ribonucleotide metabolic process 381
                      cGMP metabolic process 17
                        cGMP biosynthetic process 11
                        cGMP catabolic process 4
paths to the root