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ONTOLOGY REPORT - ANNOTATIONS


Term:cGMP metabolic process
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Accession:GO:0046068 term browser browse the term
Definition:The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
Synonyms:exact_synonym: cGMP metabolism


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cGMP metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 ISO MGI:MGI:1857092 (MGI:MGI:66348|PMID:7518067), (MGI:MGI:68066|PMID:3038581) RGD PMID:3038581, PMID:7518067 MGI:MGI:66348, MGI:MGI:68066 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Pde5a phosphodiesterase 5A ISO (MGI:MGI:4361111|PMID:19474061), (MGI:MGI:4834094|PMID:20511540) RGD PMID:19474061, PMID:20511540 MGI:MGI:4361111, MGI:MGI:4834094 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pde9a phosphodiesterase 9A ISO
ISS
(PMID:9624146)
GO_REF:0000024
RGD
UniProt
PMID:9624146 GO_REF:0000024 NCBI chr20:10,123,624...10,216,325
Ensembl chr20:10,123,651...10,216,548
JBrowse link
G Rora RAR-related orphan receptor A ISO MGI:MGI:1857035 (MGI:MGI:66348|PMID:7518067) RGD PMID:7518067 MGI:MGI:66348 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO
IEA
MGI:MGI:3640802 (MGI:MGI:3640061|PMID:16614755)
GO_REF:0000107
(PMID:23505436)
RGD
Ensembl
PMID:16614755, PMID:23505436 GO_REF:0000107, MGI:MGI:3640061 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:408,001...899,851
Ensembl chr 8:408,001...899,974
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 ISO (PMID:23505436) RGD PMID:23505436 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 IEA GO_REF:0000002
GO_REF:0000043
InterPro
UniProt
GO_REF:0000002, GO_REF:0000043 NCBI chr15:45,479,662...45,550,285
Ensembl chr15:45,479,658...45,550,285
JBrowse link
G Gucy2c guanylate cyclase 2C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:170,659,993...170,740,274
Ensembl chr 4:170,659,998...170,740,274
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal ISO
IBA
IEA
(MGI:MGI:5049799|PMID:21598940)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:21598940, PMID:21873635 GO_REF:0000107, MGI:MGI:5049799, RGD:13792537 NCBI chr10:55,835,695...55,851,235
Ensembl chr10:55,835,695...55,851,235
JBrowse link
G Gucy2e guanylate cyclase 2E IDA
IBA
PMID:11580282
PMID:21873635
UniProt
GO_Central
PMID:11580282, PMID:21873635 RGD:15023466, RGD:13792537 NCBI chr 1:163,398,891...163,433,594
Ensembl chr 1:163,398,891...163,433,593
JBrowse link
G Gucy2f guanylate cyclase 2F IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:113,372,240...113,474,210
Ensembl chr  X:113,372,240...113,474,164
JBrowse link
G Gucy2g guanylate cyclase 2G IEA
IBA
GO_REF:0000043
PMID:21873635
UniProt PMID:21873635 GO_REF:0000043, RGD:13792537 NCBI chr 1:276,187,243...276,228,574
Ensembl chr 1:276,187,242...276,228,574
JBrowse link
G Nppa natriuretic peptide A ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nppc natriuretic peptide C ISO
IBA
(PMID:1672777)
PMID:21873635
(MGI:MGI:2177134|PMID:11259675)
RGD PMID:1672777, PMID:11259675, PMID:21873635 MGI:MGI:2177134, RGD:13792537 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777, PMID:21873635 RGD:13792537 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
JBrowse link
cGMP catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde10a phosphodiesterase 10A IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
JBrowse link
G Pde1a phosphodiesterase 1A IMP RGD PMID:16514069 RGD:2312521 NCBI chr 3:66,803,247...67,263,658
Ensembl chr 3:66,803,247...66,885,094
JBrowse link
G Pde2a phosphodiesterase 2A IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:4420377|PMID:19632989)
(PMID:19828435)
Ensembl
RGD
PMID:19632989, PMID:19828435, PMID:21873635 GO_REF:0000107, MGI:MGI:4420377, RGD:13792537 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158
JBrowse link
G Pde5a phosphodiesterase 5A ISO
IEA
(MGI:MGI:2450821|PMID:12554648)
GO_REF:0000107
GO_REF:0000041
RGD
Ensembl
UniProt
PMID:12554648 GO_REF:0000041, GO_REF:0000107, MGI:MGI:2450821 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pde9a phosphodiesterase 9A IEA
ISO
ISS
IBA
GO_REF:0000041
(PMID:25799991)
GO_REF:0000024
(MGI:MGI:1266874|PMID:9624145), (MGI:MGI:5634842|PMID:25799991)
PMID:21873635
UniProt
RGD
PMID:9624145, PMID:25799991, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:MGI:1266874, MGI:MGI:5634842, RGD:13792537 NCBI chr20:10,123,624...10,216,325
Ensembl chr20:10,123,651...10,216,548
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        organophosphate metabolic process 971
          nucleoside phosphate metabolic process 510
            nucleotide metabolic process 503
              cyclic nucleotide metabolic process 42
                cGMP metabolic process 21
                  cGMP biosynthetic process 14
                  cGMP catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleobase-containing small molecule metabolic process 590
              nucleoside phosphate metabolic process 510
                nucleotide metabolic process 503
                  ribonucleotide metabolic process 411
                    purine ribonucleotide metabolic process 396
                      cGMP metabolic process 21
                        cGMP biosynthetic process 14
                        cGMP catabolic process 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.