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ONTOLOGY REPORT - ANNOTATIONS


Term:cGMP metabolic process
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Accession:GO:0046068 term browser browse the term
Definition:The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
Synonyms:exact_synonym: cGMP metabolism



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cGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857092 (MGI:66348|PMID:7518067), (MGI:68066|PMID:3038581) RGD PMID:3038581 PMID:7518067 MGI:66348 MGI:68066 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Pde5a phosphodiesterase 5A acts_upstream_of_or_within ISO (MGI:4361111|PMID:19474061), (MGI:4834094|PMID:20511540) RGD PMID:19474061 PMID:20511540 MGI:4361111 MGI:4834094 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISO
ISS
(PMID:9624146)
GO_REF:0000024
RGD
UniProt
PMID:9624146 GO_REF:0000024 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948
JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (MGI:66348|PMID:7518067) RGD PMID:7518067 MGI:66348 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3640802 (MGI:3640061|PMID:16614755)
(PMID:23505436)
Ensembl
RGD
PMID:16614755 PMID:23505436 GO_REF:0000107 MGI:3640061 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 involved_in ISO (PMID:23505436) RGD PMID:23505436 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 involved_in IEA GO_REF:0000002
GO_REF:0000043
InterPro
UniProt
GO_REF:0000002 GO_REF:0000043 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441
JBrowse link
G Gucy2c guanylate cyclase 2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal involved_in IEA
ISO
IBA
GO_REF:0000107
(MGI:5049799|PMID:21598940)
PMID:21873635
Ensembl
RGD
PMID:21598940 PMID:21873635 GO_REF:0000107 MGI:5049799, RGD:13792537 NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067
JBrowse link
G Gucy2e guanylate cyclase 2E involved_in IBA
IDA
PMID:21873635
PMID:11580282
GO_Central
UniProt
PMID:21873635 PMID:11580282 RGD:13792537, RGD:15023466 NCBI chr 1:152,739,775...152,774,474
Ensembl chr 1:152,739,775...152,774,473
JBrowse link
G Gucy2f guanylate cyclase 2F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:105,710,356...105,808,183
Ensembl chr  X:105,710,356...105,808,183
JBrowse link
G Gucy2g guanylate cyclase 2G involved_in IBA
IEA
PMID:21873635
GO_REF:0000043
UniProt PMID:21873635 GO_REF:0000043, RGD:13792537 NCBI chr 1:254,237,778...254,280,277
Ensembl chr 1:254,239,174...254,280,277
JBrowse link
G Nppa natriuretic peptide A involved_in
acts_upstream_of
IBA
IMP
ISO
PMID:21873635
(PMID:1672777)
RGD PMID:1672777 PMID:21873635 PMID:10559136 RGD:13792537, RGD:619660 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B acts_upstream_of
involved_in
ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppc natriuretic peptide C involved_in
acts_upstream_of
IBA
ISO
PMID:21873635
(MGI:2177134|PMID:11259675)
(PMID:1672777)
RGD PMID:1672777 PMID:11259675 PMID:21873635 MGI:2177134, RGD:13792537 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in IBA
ISO
PMID:21873635
(PMID:1672777)
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of
involved_in
ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
JBrowse link
cGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde10a phosphodiesterase 10A involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Pde1a phosphodiesterase 1A IMP RGD PMID:16514069 RGD:2312521 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO
IEA
IBA
(PMID:19828435)
(MGI:4420377|PMID:19632989)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:19632989 PMID:19828435 PMID:21873635 GO_REF:0000107 MGI:4420377, RGD:13792537 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pde5a phosphodiesterase 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2450821|PMID:12554648)
GO_REF:0000041
Ensembl
RGD
UniProt
PMID:12554648 GO_REF:0000041 GO_REF:0000107 MGI:2450821 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pde9a phosphodiesterase 9A involved_in IEA
ISS
IBA
ISO
GO_REF:0000041
GO_REF:0000024
PMID:21873635
(PMID:25799991)
(MGI:1266874|PMID:9624145), (MGI:5634842|PMID:25799991)
UniProt
RGD
PMID:9624145 PMID:25799991 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:1266874 MGI:5634842, RGD:13792537 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      organic substance metabolic process 11356
        organophosphate metabolic process 937
          nucleoside phosphate metabolic process 510
            nucleotide metabolic process 502
              cyclic nucleotide metabolic process 42
                cGMP metabolic process 21
                  cGMP biosynthetic process 14
                  cGMP catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      cellular metabolic process 10733
        cellular aromatic compound metabolic process 5604
          nucleobase-containing compound metabolic process 5383
            nucleobase-containing small molecule metabolic process 578
              nucleoside phosphate metabolic process 510
                nucleotide metabolic process 502
                  ribonucleotide metabolic process 419
                    purine ribonucleotide metabolic process 400
                      cGMP metabolic process 21
                        cGMP biosynthetic process 14
                        cGMP catabolic process 5
paths to the root