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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of complement activation, classical pathway
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Accession:GO:0045959 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:exact_synonym: down regulation of complement activation, classical pathway;   downregulation of complement activation, classical pathway;   negative regulation of complement cascade, classical pathway
 narrow_synonym: inhibition of complement activation, classical pathway


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negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,691,574...182,703,004
Ensembl chr 1:186,970,253...186,981,024 		JBrowse link
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G LOC100984709 C4b-binding protein alpha chain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898 		JBrowse link
G SUSD4 sushi domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    immune system process 2386
      immune effector process 638
        complement activation 54
          complement activation, classical pathway 27
            negative regulation of complement activation, classical pathway 7
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological process 10982
        regulation of immune system process 1515
          negative regulation of immune system process 529
            negative regulation of immune effector process 134
              negative regulation of leukocyte mediated immunity 73
                negative regulation of lymphocyte mediated immunity 60
                  negative regulation of B cell mediated immunity 14
                    negative regulation of immunoglobulin mediated immune response 14
                      negative regulation of humoral immune response mediated by circulating immunoglobulin 10
                        negative regulation of complement activation, classical pathway 7
paths to the root