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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of complement activation, classical pathway
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Accession:GO:0045959 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:exact_synonym: down regulation of complement activation, classical pathway;   downregulation of complement activation, classical pathway;   negative regulation of complement cascade, classical pathway
 narrow_synonym: inhibition of complement activation, classical pathway


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negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IBA
IEA		 (PMID:22333221)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:22333221 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO (PMID:22333221) RGD PMID:22333221 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA		 (PMID:9029106)
PMID:21873635		 RGD PMID:9029106 PMID:21873635 RGD:13792537 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G RGD1559810 similar to hypothetical protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:33,996,404...33,997,405
Ensembl chr20:33,996,224...33,997,432 		JBrowse link
G Susd4 sushi domain containing 4 involved_in IBA
ISO		 PMID:21873635
(PMID:23482636)		 RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750 		JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    immune system process 2730
      immune effector process 678
        complement activation 94
          complement activation, classical pathway 70
            negative regulation of complement activation, classical pathway 9
              negative regulation of complement activation, classical pathway in another organism 0
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of immune system process 1523
          negative regulation of immune system process 479
            negative regulation of immune effector process 137
              negative regulation of leukocyte mediated immunity 76
                negative regulation of lymphocyte mediated immunity 63
                  negative regulation of B cell mediated immunity 18
                    negative regulation of immunoglobulin mediated immune response 18
                      negative regulation of humoral immune response mediated by circulating immunoglobulin 12
                        negative regulation of complement activation, classical pathway 9
                          negative regulation of complement activation, classical pathway in another organism 0
paths to the root