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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of complement activation, alternative pathway
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Accession:GO:0045957 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
Synonyms:exact_synonym: down regulation of complement activation, alternative pathway;   downregulation of complement activation, alternative pathway;   negative regulation of complement cascade, alternative pathway
 narrow_synonym: inhibition of complement activation, alternative pathway



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negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO
IBA
(PMID:23482636)
GO_REF:0000033
RGD
GO_Central
PMID:23482636 GO_REF:0000033 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO
IBA
UniProtKB:P01024 (PMID:17051150)
GO_REF:0000033
RGD
GO_Central
PMID:17051150 GO_REF:0000033 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    immune system process 2984
      immune effector process 827
        complement activation 72
          complement activation, alternative pathway 14
            negative regulation of complement activation, alternative pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20325
    biological regulation 13633
      regulation of biological process 13227
        regulation of immune system process 1683
          positive regulation of immune system process 1178
            positive regulation of immune response 795
              activation of immune response 566
                complement activation 72
                  complement activation, alternative pathway 14
                    regulation of complement activation, alternative pathway 4
                      negative regulation of complement activation, alternative pathway 3
paths to the root