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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of steroid metabolic process
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Accession:GO:0045939 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: down regulation of steroid metabolic process;   downregulation of steroid metabolic process;   negative regulation of steroid metabolism
 narrow_synonym: inhibition of steroid metabolic process

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negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004936669:922,978...941,996
Ensembl chrNW_004936669:926,622...942,167 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:6,428,824...6,477,007
Ensembl chrNW_004936528:6,429,973...6,477,218 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:923,943...932,428
Ensembl chrNW_004936599:923,943...932,321 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:7,926,273...8,504,777
Ensembl chrNW_004936520:7,926,280...8,526,149 		JBrowse link
G Prox1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936628:4,185,712...4,240,680
Ensembl chrNW_004936628:4,185,706...4,238,451 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Chlsn cholesin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,213,948...1,332,534
Ensembl chrNW_004936754:1,214,480...1,324,497 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:80,583...116,027
Ensembl chrNW_004936636:80,564...116,694 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936710:1,193,679...1,210,059
Ensembl chrNW_004936710:1,193,411...1,210,739 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chrNW_004936484:13,086,928...13,092,291
Ensembl chrNW_004936484:13,088,030...13,092,291 		JBrowse link
G Insig1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,684,304...9,696,951
Ensembl chrNW_004936527:9,685,695...9,692,830 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:5,015,922...5,016,942
Ensembl chrNW_004936601:5,015,219...5,160,908 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:6,428,824...6,477,007
Ensembl chrNW_004936528:6,429,973...6,477,218 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chrNW_004936602:2,182,053...2,185,297
Ensembl chrNW_004936602:2,183,831...2,185,297 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,684,304...9,696,951
Ensembl chrNW_004936527:9,685,695...9,692,830 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:52,120,063...52,140,646
Ensembl chrNW_004936469:52,117,733...52,140,765 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936553:6,436,371...6,440,141
Ensembl chrNW_004936553:6,436,371...6,440,141 		JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936549:5,212,693...5,450,195
Ensembl chrNW_004936549:5,212,834...5,448,515 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,257,744...3,263,787
Ensembl chrNW_004936664:3,257,698...3,264,565 		JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087 		JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936537:6,610,565...6,618,509
Ensembl chrNW_004936537:6,610,565...6,618,450 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17012
      metabolic process 11289
        negative regulation of metabolic process 2841
          negative regulation of lipid metabolic process 105
            negative regulation of steroid metabolic process 28
              negative regulation of aldosterone metabolic process + 4
              negative regulation of bile acid metabolic process + 3
              negative regulation of cholesterol metabolic process + 7
              negative regulation of ecdysteroid metabolic process + 0
              negative regulation of glucocorticoid metabolic process + 5
              negative regulation of steroid biosynthetic process + 26
Path 2
Term Annotations click to browse term
  biological_process 17413
    biological regulation 11396
      regulation of biological process 11032
        regulation of cellular process 10707
          regulation of metabolic process 5854
            regulation of primary metabolic process 4771
              regulation of lipid metabolic process 358
                negative regulation of lipid metabolic process 105
                  negative regulation of steroid metabolic process 28
                    negative regulation of aldosterone metabolic process + 4
                    negative regulation of bile acid metabolic process + 3
                    negative regulation of cholesterol metabolic process + 7
                    negative regulation of ecdysteroid metabolic process + 0
                    negative regulation of glucocorticoid metabolic process + 5
                    negative regulation of steroid biosynthetic process + 26
paths to the root