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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of steroid metabolic process
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Accession:GO:0045939 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.
Synonyms:exact_synonym: down regulation of steroid metabolic process;   downregulation of steroid metabolic process;   negative regulation of steroid metabolism
 narrow_synonym: inhibition of steroid metabolic process


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negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:112,116,019...112,159,482
Ensembl chr 7:112,116,017...112,159,057
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:77,265,494...77,286,432
Ensembl chr 5:77,265,491...77,286,432
JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf15 fibroblast growth factor 15 involved_in
acts_upstream_of_or_within
ISO
IGI
(MGI:5501367|PMID:23747249) MGI PMID:23747249 GO_REF:0000096 MGI:4834177 MGI:5501367 NCBI chr 7:144,896,532...144,900,953
Ensembl chr 7:144,896,531...144,900,953
JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within IMP
IGI
(MGI:5501367|PMID:23747249) MGI PMID:23747249 MGI:5501367 NCBI chr 2:15,526,479...16,255,557
Ensembl chr 2:15,526,479...16,255,555
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:190,118,035...190,170,827
Ensembl chr 1:190,118,035...190,170,714
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:127,048,246...127,054,884
Ensembl chr10:127,048,250...127,053,006
JBrowse link
G Gfi1 growth factor independent 1 transcription repressor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:107,716,655...107,725,805
Ensembl chr 5:107,716,657...107,726,036
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI
RGD
PMID:9225228 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:10059686 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:44,034,943...44,070,164
Ensembl chr19:44,034,944...44,069,785
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:27,023,371...27,039,437
Ensembl chr 8:27,023,261...27,040,328
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within IMP (MGI:5490819|PMID:17202134) MGI PMID:17202134 MGI:5490819 NCBI chr13:8,952,863...8,960,935
Ensembl chr13:8,952,863...8,960,945
JBrowse link
G Sod1 superoxide dismutase 1, soluble involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:112,116,019...112,159,482
Ensembl chr 7:112,116,017...112,159,057
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:77,265,494...77,286,432
Ensembl chr 5:77,265,491...77,286,432
JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide acts_upstream_of_or_within IMP (MGI:3696486|PMID:17234593) MGI PMID:17234593 MGI:3696486 NCBI chr 3:101,576,219...101,604,707
Ensembl chr 3:101,576,219...101,604,684
JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:133,552,159...133,562,896
Ensembl chr 2:133,552,159...133,562,885
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Hrh1 histamine receptor H1 involved_in ISO RGD
MGI
PMID:15917347 GO_REF:0000096 MGI:4417868 RGD:2316921 NCBI chr 6:114,397,936...114,483,298
Ensembl chr 6:114,397,936...114,483,296
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within IGI (MGI:3603108|PMID:16100574) MGI PMID:16100574 MGI:3603108 NCBI chr 5:28,071,412...28,078,662
Ensembl chr 5:28,071,363...28,078,662
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within IGI (MGI:3603108|PMID:16100574) MGI PMID:16100574 MGI:3603108 NCBI chr 1:121,304,353...121,332,662
Ensembl chr 1:121,304,353...121,332,589
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:86,191,775...86,195,947
Ensembl chr  X:86,191,764...86,195,947
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within IMP (MGI:5526088|PMID:21187369) MGI PMID:21187369 MGI:5526088 NCBI chr13:95,024,105...95,250,401
Ensembl chr13:95,024,454...95,250,336
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf-like 1 involved_in IMP (MGI:3839065|PMID:18818293) UniProt PMID:18818293 MGI:3839065 NCBI chr 7:45,207,525...45,212,165
Ensembl chr 7:45,207,519...45,212,147
JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO
IMP
(MGI:2675528|PMID:12949260) MGI
UniProt
PMID:12949260 GO_REF:0000096 MGI:2675528 MGI:4834177 NCBI chr 4:137,277,635...137,299,501
Ensembl chr 4:137,277,489...137,299,726
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family zinc finger 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:167,538,195...167,542,814
Ensembl chr 2:167,538,195...167,542,814
JBrowse link
G Snai2 snail family zinc finger 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:14,705,852...14,709,395
Ensembl chr16:14,705,852...14,709,385
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28599
    metabolic process 11227
      negative regulation of metabolic process 3239
        negative regulation of lipid metabolic process 111
          negative regulation of steroid metabolic process 26
            negative regulation of aldosterone metabolic process + 4
            negative regulation of bile acid metabolic process + 3
            negative regulation of cholesterol esterification 1
            negative regulation of cholesterol metabolic process + 5
            negative regulation of ecdysteroid metabolic process + 0
            negative regulation of glucocorticoid metabolic process + 5
            negative regulation of steroid biosynthetic process + 25
Path 2
Term Annotations click to browse term
  biological_process 28599
    biological regulation 13246
      regulation of biological process 12592
        regulation of metabolic process 6881
          regulation of primary metabolic process 5797
            regulation of lipid metabolic process 390
              regulation of steroid metabolic process 119
                negative regulation of steroid metabolic process 26
                  negative regulation of aldosterone metabolic process + 4
                  negative regulation of bile acid metabolic process + 3
                  negative regulation of cholesterol esterification 1
                  negative regulation of cholesterol metabolic process + 5
                  negative regulation of ecdysteroid metabolic process + 0
                  negative regulation of glucocorticoid metabolic process + 5
                  negative regulation of steroid biosynthetic process + 25
paths to the root