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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphate metabolic process
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Accession:GO:0045936 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
Synonyms:exact_synonym: down regulation of phosphate metabolic process;   downregulation of phosphate metabolic process;   negative regulation of phosphate metabolism
 narrow_synonym: inhibition of phosphate metabolic process


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negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr10:22,691,355...22,870,628 JBrowse link
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr17:18,471,609...18,507,916
Ensembl chr17:18,746,712...18,782,296
JBrowse link
G PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in ISO (PMID:31091439) UniProt PMID:31091439 NCBI chr12:31,323,346...31,335,626
Ensembl chr12:31,584,534...31,594,808
JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (PMID:16254138) UniProt PMID:16254138 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536
JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G HPN hepsin acts_upstream_of_or_within ISO (MGI:5437809|PMID:22912808) MGI PMID:22912808 MGI:5437809 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628
JBrowse link
G SEMA4D semaphorin 4D involved_in ISO (PMID:22019888)
(MGI:5297297|PMID:22019888)
BHF-UCL PMID:22019888 MGI:5297297 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:18358889) BHF-UCL PMID:18358889 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TNF tumor necrosis factor involved_in ISO (MGI:5285024|PMID:21689636) BHF-UCL PMID:21689636 MGI:5285024 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:92,365,267...92,511,852
Ensembl chr10:95,828,094...95,983,257
JBrowse link
G FLCN folliculin involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr2B:116,265,529...116,517,557 JBrowse link
negative regulation of brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM72A family with sequence similarity 72 member A acts_upstream_of_or_within ISO PMID:19755123 MGI PMID:19755123 RGD:8553945 NCBI chr 1:181,792,764...181,811,141 JBrowse link
negative regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKIA cAMP-dependent protein kinase inhibitor alpha involved_in
acts_upstream_of_or_within
ISO (PMID:21812984)
(PMID:7905001)
BHF-UCL
MGI
PMID:7905001 PMID:21812984 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta acts_upstream_of_or_within ISO (MGI:3793555|PMID:7905001) MGI PMID:7905001 MGI:3793555 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943
JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr 7:700,691...876,497
Ensembl chr 7:923,668...1,097,456
JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394)
(PMID:21812984)
AgBase
BHF-UCL
PMID:21812984 PMID:22674394 NCBI chr 3:48,665,421...48,774,111
Ensembl chr 3:49,747,611...49,854,382
JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta involved_in ISO (PMID:21812984) BHF-UCL PMID:21812984 NCBI chr 7:99,021,209...99,140,652
Ensembl chr 7:111,748,463...111,866,044
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:20203304) UniProt PMID:20203304 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 involved_in ISO (PMID:18305109) UniProt PMID:18305109 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:8876165) CAFA PMID:8876165 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:8684460) CAFA PMID:8684460 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:11746698) CAFA PMID:11746698 NCBI chr11:2,908,537...2,911,134 JBrowse link
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway involved_in ISO (PMID:8521819) UniProt PMID:8521819 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G CASP3 caspase 3 acts_upstream_of_or_within ISO (MGI:2677082|PMID:12970760) MGI PMID:12970760 MGI:2677082 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 involved_in ISO (PMID:11882646) UniProt PMID:11882646 NCBI chr20:29,648,003...29,690,210
Ensembl chr20:30,762,967...30,804,237
JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 ISO RGD PMID:10721722 RGD:632478 NCBI chr 9:91,519,179...91,707,469
Ensembl chr 9:119,868,015...120,055,608
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:2183076|PMID:12130539) MGI PMID:12130539 MGI:2183076 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in
ISO (MGI:2183076|PMID:12130539)
(PMID:28666995)
RGD
MGI
UniProt
PMID:12130539 PMID:22584582 PMID:28666995 MGI:2183076 RGD:10045364 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in
ISO (MGI:2183076|PMID:12130539)
(PMID:7739547)
(PMID:8259215)
MGI
BHF-UCL
PMID:7739547 PMID:8259215 PMID:12130539 MGI:2183076 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (MGI:72259|PMID:7739547) MGI PMID:7739547 MGI:72259 NCBI chr 1:50,214,767...50,221,465
Ensembl chr 1:51,704,528...51,718,374
JBrowse link
G FBXO7 F-box protein 7 acts_upstream_of_or_within ISO (MGI:5317390|PMID:21652635) MGI PMID:21652635 MGI:5317390 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224
JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:14580347) HGNC-UCL PMID:14580347 NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669
JBrowse link
G HEXIM2 HEXIM P-TEFb complex subunit 2 involved_in ISO (PMID:15713662) HGNC-UCL PMID:15713662 NCBI chr17:12,157,392...12,167,281
Ensembl chr17:12,333,957...12,343,399
JBrowse link
G HHEX hematopoietically expressed homeobox involved_in ISO (PMID:12554669) BHF-UCL PMID:12554669 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO (MGI:5286822|PMID:21540187)
(PMID:21540187)
MGI PMID:21540187 MGI:5286822 NCBI chr17:5,036,659...5,046,146
Ensembl chr17:5,024,740...5,034,216
JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in ISO (MGI:4410401|PMID:19773423) UniProt PMID:19773423 MGI:4410401 NCBI chr 3:19,956,067...20,070,637
Ensembl chr 3:20,286,865...20,400,770
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in ISO (PMID:9988268) UniProt PMID:9988268 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276
JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) UniProt PMID:12853976 NCBI chr13:2,300,625...2,389,027
Ensembl chr13:20,611,861...20,683,083
JBrowse link
G MEN1 menin 1 involved_in ISO (PMID:15640349) UniProt PMID:15640349 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G MYOCD myocardin involved_in ISO (PMID:18451334) BHF-UCL PMID:18451334 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659
JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 involved_in ISO (PMID:19210544) BHF-UCL PMID:19210544 NCBI chr15:75,008,879...75,021,981 JBrowse link
G PLK1 polo like kinase 1 involved_in ISO (PMID:21041660) BHF-UCL PMID:21041660 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G TFAP4 transcription factor AP-4 involved_in ISO (PMID:18818310) UniProt PMID:18818310 NCBI chr16:3,176,129...3,226,404
Ensembl chr16:4,348,929...4,368,525
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in ISO (MGI:4943408|PMID:15962316) BHF-UCL PMID:15962316 MGI:4943408 NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819
JBrowse link
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (MGI:4948986|PMID:21454751) UniProt PMID:21454751 MGI:4948986 NCBI chr 7:133,635,359...133,663,153
Ensembl chr 7:146,110,121...146,132,872
JBrowse link
negative regulation of dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPM2A EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) UniProt PMID:18617530 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (MGI:5294535|PMID:19250614) UniProt PMID:19250614 MGI:5294535 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 acts_upstream_of_or_within ISO (MGI:5085959|PMID:21709260) MGI PMID:21709260 MGI:5085959 NCBI chr15:69,076,025...69,190,082
Ensembl chr15:88,276,851...88,388,594
JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO (PMID:22064321)
(MGI:5617428|PMID:25329545)
ParkinsonsUK-UCL
UniProt
PMID:22064321 PMID:25329545 MGI:5617428 NCBI chr13:76,853,053...76,963,530
Ensembl chr13:96,033,605...96,114,165
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in ISO (PMID:14676213), (PMID:16835242)
(MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
ParkinsonsUK-UCL PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (PMID:16835242)
(MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
ParkinsonsUK-UCL PMID:14676213 PMID:16835242 MGI:5613475 MGI:5613478 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:5613475 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:5613475 NCBI chr 1:180,002,895...180,014,956
Ensembl chr 1:184,293,640...184,302,316
JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (MGI:5914333|PMID:28797121) MGI PMID:28797121 MGI:5914333 NCBI chr12:121,169,915...121,183,524
Ensembl chr12:125,397,391...125,410,794
JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO (PMID:18046415)
(MGI:3629275|PMID:16648858)
PMID:17599051
UniProt PMID:16648858 PMID:17599051 PMID:18046415 MGI:3629275 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A involved_in ISO (MGI:5635952|PMID:25744720) UniProt PMID:25744720 MGI:5635952 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727
JBrowse link
G PSEN1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041
JBrowse link
G TSG101 tumor susceptibility 101 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149
JBrowse link
G VPS25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:14,538,322...14,544,573
Ensembl chr17:14,763,523...14,769,672
JBrowse link
G ZFYVE28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) UniProt PMID:19460345 NCBI chr 4:2,412,659...2,564,741
Ensembl chr 4:2,320,446...2,470,638
JBrowse link
G ZGPAT zinc finger CCCH-type and G-patch domain containing involved_in ISO (PMID:19644445) UniProt PMID:19644445 Ensembl chr20:61,630,271...61,662,967 JBrowse link
negative regulation of glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXA2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) BHF-UCL PMID:11875061 MGI:5142372 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GCKR glucokinase regulator involved_in
acts_upstream_of_or_within
ISO PMID:14627435
(MGI:1354534|PMID:10713097)
(PMID:14627435), (PMID:23621087)
BHF-UCL
MGI
PMID:10713097 PMID:14627435 PMID:23621087 MGI:1354534 RGD:1598592 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927
JBrowse link
G LOC100976343 cytochrome c oxidase assembly protein COX11, mitochondrial acts_upstream_of_or_within ISO (MGI:3693040|PMID:17069463) MGI PMID:17069463 MGI:3693040 NCBI chr17:49,009,099...49,058,145
Ensembl chr17:53,915,841...53,923,431
JBrowse link
G MIDN midnolin acts_upstream_of_or_within ISO PMID:24187134 MGI PMID:24187134 RGD:8655525
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:24187134) MGI PMID:24187134 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chr16:69,592,293...69,662,321
Ensembl chr16:89,246,545...89,347,435
JBrowse link
G DDIT4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (MGI:4440406|PMID:20176937) MGI PMID:20176937 MGI:4440406 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in ISO (PMID:25043030)
(PMID:19881551)
CAFA
UniProt
PMID:19881551 PMID:25043030 NCBI chr 9:65,695,082...65,731,628
Ensembl chr 9:93,825,150...93,860,968
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in ISO (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857
JBrowse link
G HDAC4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) MGI PMID:19096392 MGI:4437986 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (MGI:5662300|PMID:26219591) MGI PMID:26219591 MGI:5662300 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 1:178,684,933...178,687,971
Ensembl chr 1:182,979,700...182,982,611
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:34,934,452...35,121,195 JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:30451898) UniProt PMID:30451898 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) CACAO PMID:20141841 PMID:23217706 MGI:4881401 MGI:5619441 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5441121|PMID:22891351) MGI PMID:22891351 MGI:5441121 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (MGI:3820439|PMID:18698006) MGI PMID:18698006 MGI:3820439 NCBI chr17:13,131,851...13,150,872
Ensembl chr17:13,302,796...13,317,312
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524
JBrowse link
G RD3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)
UniProt PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr 1:187,044,054...187,060,441
Ensembl chr 1:191,907,989...191,924,365
JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCKR glucokinase regulator ISO RGD PMID:14627435 RGD:1598592 NCBI chr2A:27,497,938...27,530,650
Ensembl chr2A:27,587,077...27,613,927
JBrowse link
negative regulation of histone phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100974858 core histone macro-H2A.1 involved_in ISO (PMID:22194607) UniProt PMID:22194607 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) BHF-UCL PMID:17690110 NCBI chr 7:19,761,041...19,765,665 JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B acts_upstream_of_or_within ISO (MGI:3720437|PMID:17488778) MGI PMID:17488778 MGI:3720437 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
negative regulation of I-kappaB phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLEK pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) BHF-UCL PMID:7559487 PMID:7782310 NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:7535379 RGD:7777104 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated acts_upstream_of_or_within ISO (MGI:3799599|PMID:17681137)
(PMID:17681137)
MGI PMID:17681137 MGI:3799599 NCBI chr 1:198,341,375...198,385,682 JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:24512202) UniProt PMID:24512202 NCBI chr 9:32,800,077...32,814,745
Ensembl chr 9:33,608,502...33,622,275
JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within
ISO (PMID:10391943)
(MGI:3051749|PMID:15306813)
BHF-UCL
MGI
PMID:10391943 PMID:15306813 MGI:3051749 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720
JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664)
(MGI:5009198|PMID:10945608), (MGI:5009411|PMID:16023107)
(MGI:3721484|PMID:12646564)
BHF-UCL PMID:10945608 PMID:12646564 PMID:16023107 PMID:16636664 MGI:3721484 MGI:5009198 MGI:5009411 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 involved_in ISO (MGI:1913166|PMID:11034606) UniProt PMID:11034606 MGI:1913166 NCBI chr11:33,230,731...33,330,617
Ensembl chr11:33,114,534...33,212,783
JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISO PMID:21076496 RGD
UniProt
PMID:12064607 PMID:21076496 RGD:1299562 RGD:13673827 NCBI chr11:45,839,754...45,860,615
Ensembl chr11:46,332,159...46,352,010
JBrowse link
G NPPA natriuretic peptide A involved_in ISO (PMID:22399583) UniProt PMID:22399583 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
G SFRP1 secreted frizzled related protein 1 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SFRP5 secreted frizzled related protein 5 acts_upstream_of_or_within ISO (MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:3839161 NCBI chr10:94,383,269...94,389,053
Ensembl chr10:97,877,790...97,882,850
JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) MGI PMID:15483136 MGI:3574697 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein acts_upstream_of_or_within ISO (MGI:3581335|PMID:15870270) MGI PMID:15870270 MGI:3581335 NCBI chr14:3,791,309...3,802,763
Ensembl chr14:21,889,443...21,900,700
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:19170105) UniProt PMID:19170105 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031
JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (MGI:3851274|PMID:19523444) BHF-UCL PMID:19523444 MGI:3851274 NCBI chr13:90,886,095...90,917,724 JBrowse link
G LOC100995589 uncharacterized LOC100995589 involved_in ISO (PMID:24391509) UniProt PMID:24391509 NCBI chr2A:15,923,366...15,926,680 JBrowse link
G MAPT microtubule associated protein tau involved_in ISO (PMID:20655099) ParkinsonsUK-UCL PMID:20655099 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G MSTN myostatin involved_in ISO (MGI:5619470|PMID:19357233) CACAO PMID:19357233 MGI:5619470 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922
JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit involved_in ISO (PMID:18616680) UniProt PMID:18616680 NCBI chr 3:50,273,611...50,277,175
Ensembl chr 3:51,508,932...51,512,776
JBrowse link
G PRDX3 peroxiredoxin 3 involved_in ISO (PMID:18205602) UniProt PMID:18205602 NCBI chr10:115,738,346...115,749,482
Ensembl chr10:119,162,714...119,173,845
JBrowse link
G PRPSAP1 phosphoribosyl pyrophosphate synthetase associated protein 1 ISO RGD PMID:9366267 RGD:5134981 NCBI chr17:70,258,663...70,302,287
Ensembl chr17:75,810,423...75,853,442
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr12:825,659...985,016
Ensembl chr12:791,153...944,602
JBrowse link
negative regulation of lipid kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP2R5A protein phosphatase 2 regulatory subunit B'alpha involved_in ISO (PMID:21075214) BHF-UCL PMID:21075214 NCBI chr 1:187,853,674...187,926,318
Ensembl chr 1:192,716,546...192,788,328
JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (MGI:4943654|PMID:19460854) UniProt PMID:19460854 MGI:4943654 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AGT angiotensinogen involved_in ISO (PMID:28283184) CACAO PMID:28283184 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:9685360) BHF-UCL PMID:9685360 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of ISO (PMID:18382765) BHF-UCL PMID:18382765 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (MGI:3703676|PMID:12388746) MGI PMID:12388746 MGI:3703676 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CAV3 caveolin 3 involved_in ISO (PMID:12847114) BHF-UCL PMID:12847114 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:16254138) UniProt PMID:16254138 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:21283629) UniProt PMID:21283629 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:12813029)
(PMID:20154697)
BHF-UCL PMID:12813029 PMID:20154697 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G DEFB114 defensin beta 114 involved_in ISO (PMID:23482568) UniProt PMID:23482568 NCBI chr 6:49,527,541...49,531,451
Ensembl chr 6:50,787,203...50,791,015
JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in ISO (PMID:7593328) UniProt PMID:7593328 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP7 dual specificity phosphatase 7 involved_in ISO (PMID:9788880) UniProt PMID:9788880 NCBI chr 3:51,990,115...51,997,627
Ensembl chr 3:53,219,167...53,226,491
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:17182785 RGD:2301767 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:11408560) BHF-UCL PMID:11408560 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase acts_upstream_of_or_within ISO (MGI:3610917|PMID:12409258) MGI PMID:12409258 MGI:3610917 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785
JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551
JBrowse link
G IL1B interleukin 1 beta involved_in ISO (MGI:3828398|PMID:16865359) BHF-UCL PMID:16865359 MGI:3828398 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:12933696 RGD:1626126 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:17379480)
(MGI:3843426|PMID:17379480)
BHF-UCL PMID:17379480 MGI:3843426 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148
JBrowse link
G KNG1 kininogen 1 ISO in ConA- or PHA-stimulated Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 involved_in ISO (PMID:12359715) HGNC-UCL PMID:12359715 NCBI chr 1:179,370,097...179,379,618
Ensembl chr 1:183,660,297...183,671,335
JBrowse link
G LOC100973655 protein fem-1 homolog A acts_upstream_of_or_within ISO (MGI:3790904|PMID:18270204) MGI PMID:18270204 MGI:3790904 NCBI chr21:468,156...495,596
Ensembl chr19:4,763,674...4,765,683
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:894972|PMID:9252121) UniProt PMID:9252121 MGI:894972 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 acts_upstream_of_or_within ISO (MGI:1933463|PMID:11139578), (MGI:2135469|PMID:11381262) MGI PMID:11139578 PMID:11381262 MGI:1933463 MGI:2135469 NCBI chr17:31,729,429...31,736,216
Ensembl chr17:36,894,146...36,899,969
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:1932841|PMID:11297510)
(MGI:3610917|PMID:12409258)
(MGI:1351242|PMID:10620616)
MGI PMID:10620616 PMID:11297510 PMID:12409258 MGI:1351242 MGI:1932841 MGI:3610917 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (MGI:3526674|PMID:11489947) UniProt PMID:11489947 MGI:3526674 NCBI chr19:46,919,731...46,942,318 JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (MGI:3722998|PMID:17724343)
(PMID:17724343)
MGI PMID:17724343 MGI:3722998 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in ISO (MGI:6444553|PMID:30496354) BHF-UCL PMID:30496354 MGI:6444553 NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:18382765) BHF-UCL PMID:18382765 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:22045810) CACAO PMID:22045810 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 RGD:10044039 NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656), (MGI:82729|PMID:9064344) MGI PMID:9064344 PMID:9254656 MGI:1095647 MGI:82729 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:19494114)
(MGI:4942250|PMID:12833140)
UniProt PMID:12833140 PMID:19494114 MGI:4942250 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G RGS14 regulator of G protein signaling 14 involved_in ISO (MGI:4834960|PMID:20837545) UniProt PMID:20837545 MGI:4834960 NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453
JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955
JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in ISO (MGI:3510267|PMID:15337790) ARUK-UCL PMID:15337790 MGI:3510267 NCBI chr12:108,977,344...109,024,029 JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SORL1 sortilin related receptor 1 involved_in ISO (MGI:3801250|PMID:18362153) Alzheimers_University_of_Toronto PMID:18362153 MGI:3801250 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432
JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 acts_upstream_of_or_within ISO (MGI:3614383|PMID:16339969) MGI PMID:16339969 MGI:3614383 NCBI chr 5:137,667,280...137,683,578
Ensembl chr 5:143,778,785...143,791,939
JBrowse link
G STK38 serine/threonine kinase 38 involved_in ISO (PMID:17906693) UniProt PMID:17906693 NCBI chr 6:36,056,585...36,110,531
Ensembl chr 6:37,255,183...37,308,102
JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:14612383 RGD:1580517 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:19477270) BHF-UCL PMID:19477270 NCBI chr 4:35,580,755...35,592,314
Ensembl chr 4:41,428,759...41,440,129
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr 8:41,515,613...41,576,229
Ensembl chr 8:38,960,594...39,020,971
JBrowse link
G MPRIP myosin phosphatase Rho interacting protein ISO RGD PMID:17661354 RGD:9685557 NCBI chr17:34,101,451...34,251,475
Ensembl chr17:39,040,719...39,182,578
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:16417406) UniProt PMID:16417406 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986
JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP22 dual specificity phosphatase 22 involved_in ISO (PMID:20018849) ARUK-UCL PMID:20018849 NCBI chr 6:107,145...180,777
Ensembl chr 6:242,121...301,248
JBrowse link
negative regulation of nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDA cytidine deaminase involved_in ISO (PMID:9596658) UniProt PMID:9596658 NCBI chr 1:19,538,696...19,568,008
Ensembl chr 1:20,583,441...20,612,711
JBrowse link
negative regulation of pathway-restricted SMAD protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:5605894 NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525
JBrowse link
G ENG endoglin involved_in ISO (PMID:18974388) BHF-UCL PMID:18974388 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:11,213,870...11,230,619 JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) UniProt PMID:24627487 NCBI chr18:669,862...1,110,558
Ensembl chr18:2,845,198...2,879,363
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G NOG noggin involved_in ISO (PMID:15539560)
(MGI:3783944|PMID:17218603)
BHF-UCL PMID:15539560 PMID:17218603 MGI:3783944 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092
JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in ISO (PMID:24627487)
(MGI:5582164|PMID:20129061)
(PMID:20129061)
UniProt PMID:20129061 PMID:24627487 MGI:5582164 NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28467929), (PMID:31023188) BHF-UCL PMID:28467929 PMID:31023188 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G SMAD6 SMAD family member 6 involved_in ISO (PMID:19047146)
(PMID:9436979)
BHF-UCL PMID:9436979 PMID:19047146 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:17438144) BHF-UCL PMID:17438144 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SNX25 sorting nexin 25 involved_in ISO (PMID:21266196) UniProt PMID:21266196 NCBI chr 4:177,377,302...177,529,601
Ensembl chr 4:189,631,239...189,746,590
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of peptidyl-serine dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in ISO (PMID:25007873) GO_Central PMID:25007873 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 involved_in ISO (MGI:5554982|PMID:23921380) CACAO PMID:23921380 MGI:5554982 NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of peptidyl-serine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:3527292|PMID:15613488) MGI PMID:15613488 MGI:3527292 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:3527292|PMID:15613488) MGI PMID:15613488 MGI:3527292 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BDKRB2 bradykinin receptor B2 acts_upstream_of_or_within ISO (MGI:3654719|PMID:16571598) MGI PMID:16571598 MGI:3654719 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:18081315) BHF-UCL PMID:18081315 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CNKSR3 CNKSR family member 3 involved_in ISO (MGI:4457233|PMID:19567370) UniProt PMID:19567370 MGI:4457233 NCBI chr 6:152,221,458...152,326,885 JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in ISO PMID:19118169 UniProt PMID:19118169 RGD:8554415 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20723538) BHF-UCL PMID:20723538 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G DMD dystrophin involved_in ISO (MGI:5487906|PMID:23263329) BHF-UCL PMID:23263329 MGI:5487906 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO (MGI:3826692|PMID:18824542) MGI PMID:18824542 MGI:3826692 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:19666841) BHF-UCL PMID:19666841 NCBI chr 3:32,026,586...32,088,512
Ensembl chr 3:32,342,776...32,404,172
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO Akt1 RGD PMID:26660861 RGD:13514041 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G HGF hepatocyte growth factor acts_upstream_of_or_within ISO (MGI:4849876|PMID:21072211) MGI PMID:21072211 MGI:4849876 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F involved_in ISO PMID:26908121 ParkinsonsUK-UCL PMID:26908121 RGD:11059577 NCBI chr10:116,295,802...116,396,764
Ensembl chr10:119,712,696...119,813,444
JBrowse link
G INPP5J inositol polyphosphate-5-phosphatase J acts_upstream_of_or_within ISO (MGI:3654813|PMID:16280363) MGI PMID:16280363 MGI:3654813 NCBI chr22:12,131,746...12,158,481
Ensembl chr22:29,984,096...29,995,256
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in
acts_upstream_of_or_within
ISO (PMID:12556481)
(MGI:3810008|PMID:18573875)
(MGI:5294535|PMID:19250614)
UniProt
MGI
PMID:12556481 PMID:18573875 PMID:19250614 MGI:3810008 MGI:5294535 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G MLXIPL MLX interacting protein like involved_in ISO (PMID:19995986) BHF-UCL PMID:19995986 Ensembl chr 7:80,745,765...80,776,153 JBrowse link
G NCK1 NCK adaptor protein 1 involved_in ISO (PMID:14676213), (PMID:16835242) ParkinsonsUK-UCL PMID:14676213 PMID:16835242 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (PMID:16835242) ParkinsonsUK-UCL PMID:16835242 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in ISO (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:49,995,556...49,998,734 JBrowse link
G NOS1 nitric oxide synthase 1 involved_in ISO PMID:19278978 BHF-UCL PMID:19278978 RGD:10047220 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO Akt1 RGD PMID:21712532 RGD:9590189 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (PMID:17724343) MGI PMID:17724343 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:3690823|PMID:16213210) BHF-UCL PMID:16213210 MGI:3690823 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:15140879) UniProt PMID:15140879 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:10918569) UniProt PMID:10918569 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in ISO (PMID:20103773) ParkinsonsUK-UCL PMID:20103773 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128
JBrowse link
G RASSF2 Ras association domain family member 2 acts_upstream_of_or_within ISO (PMID:19962960) MGI PMID:19962960 NCBI chr20:4,804,802...4,845,633
Ensembl chr20:4,603,414...4,641,529
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:18593713)
(MGI:5532916|PMID:18593713)
BHF-UCL PMID:18593713 MGI:5532916 NCBI chr18:42,306,324...42,337,214 JBrowse link
negative regulation of peptidyl-serine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:23329839)
(MGI:6377865|PMID:23329839)
CACAO PMID:23329839 MGI:6377865 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (MGI:5779255|PMID:26764350) MGI PMID:26764350 MGI:5779255 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055
JBrowse link
G PWP1 PWP1 homolog, endonuclein acts_upstream_of_or_within ISO (MGI:5659778|PMID:25335925) MGI PMID:25335925 MGI:5659778 NCBI chr12:105,255,755...105,282,519
Ensembl chr12:108,652,024...108,679,503
JBrowse link
negative regulation of peptidyl-threonine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM4 cell adhesion molecule 4 involved_in ISO (PMID:23611113)
(MGI:6270911|PMID:23611113)
UniProt PMID:23611113 MGI:6270911 NCBI chr19:40,564,288...40,581,830 JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in ISO PMID:19118169 UniProt PMID:19118169 RGD:8554415 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DGKQ diacylglycerol kinase theta involved_in ISO (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724
JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:18426977) ParkinsonsUK-UCL PMID:18426977 NCBI chr 3:181,351,938...181,372,776
Ensembl chr 3:189,833,490...189,855,060
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO Akt1 RGD PMID:26660861 RGD:13514041 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO MAP2 RGD PMID:18262389 RGD:2317458 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO Akt1 RGD PMID:21712532 RGD:9590189 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PARD3 par-3 family cell polarity regulator involved_in ISO (MGI:5295137|PMID:21949390) UniProt PMID:21949390 MGI:5295137 NCBI chr10:34,225,791...34,933,907
Ensembl chr10:34,808,380...35,393,287
JBrowse link
G PPEF2 protein phosphatase with EF-hand domain 2 involved_in ISO (PMID:20674765) BHF-UCL PMID:20674765 NCBI chr 4:48,308,761...48,345,861
Ensembl chr 4:54,141,778...54,184,351
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Tsc2 RGD PMID:21925170 RGD:9999170 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta ISO RGD PMID:17301223 RGD:13515116 NCBI chr 6:42,576,759...42,604,609
Ensembl chr 6:43,871,915...43,899,183
JBrowse link
G SIRT2 sirtuin 2 involved_in ISO (MGI:5295137|PMID:21949390) UniProt PMID:21949390 MGI:5295137 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:18593713)
(MGI:5532916|PMID:18593713)
BHF-UCL PMID:18593713 MGI:5532916 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in ISO (PMID:20736167)
(MGI:5318016|PMID:20736167)
BHF-UCL PMID:20736167 MGI:5318016 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (PMID:20736167)
(MGI:5318016|PMID:20736167)
BHF-UCL PMID:20736167 MGI:5318016 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:20736167) BHF-UCL PMID:20736167 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928
JBrowse link
negative regulation of peptidyl-tyrosine autophosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in ISO (PMID:25006397)
(MGI:5607357|PMID:25017399)
BHF-UCL PMID:25006397 PMID:25017399 MGI:5607357 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
negative regulation of peptidyl-tyrosine phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM4 cell adhesion molecule 4 involved_in ISO (PMID:23611113)
(MGI:6270911|PMID:23611113)
UniProt PMID:23611113 MGI:6270911 NCBI chr19:40,564,288...40,581,830 JBrowse link
G DMTN dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) UniProt PMID:18505823 MGI:3803395 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO PMID:17599051 UniProt PMID:17599051 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:5433272|PMID:21677284) MGI PMID:21677284 MGI:5433272 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:22001439 RGD:8655996 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G LRRK1 leucine rich repeat kinase 1 acts_upstream_of_or_within ISO (MGI:5564766|PMID:23526378) MGI PMID:23526378 MGI:5564766 NCBI chr15:79,642,908...79,793,990
Ensembl chr15:98,931,344...99,081,168
JBrowse link
G NTF3 neurotrophin 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (MGI:3843438|PMID:14583092) BHF-UCL PMID:14583092 MGI:3843438 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PRKCZ protein kinase C zeta involved_in ISO (PMID:15069075) BHF-UCL PMID:15069075 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
ISO (PMID:19749791)
(MGI:1095647|PMID:9254656)
BHF-UCL
MGI
PMID:9254656 PMID:19749791 MGI:1095647 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277) MGI PMID:7499277 PMID:8175795 MGI:65996 MGI:77358 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 involved_in ISO (MGI:4437539|PMID:19923443) UniProt PMID:19923443 MGI:4437539 NCBI chr21:1,228,632...1,399,331
Ensembl chr21:14,595,688...14,711,613
JBrowse link
G SEMA4D semaphorin 4D involved_in ISO (MGI:5297297|PMID:22019888) BHF-UCL PMID:22019888 MGI:5297297 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in ISO (PMID:10980594) UniProt PMID:10980594 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in ISO (MGI:4835154|PMID:10980594) UniProt PMID:10980594 MGI:4835154 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (MGI:5428115|PMID:22228629) MGI PMID:22228629 MGI:5428115 NCBI chr 5:143,273,137...143,287,745 JBrowse link
negative regulation of phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO (PMID:10593895) UniProt PMID:10593895 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) UniProt PMID:18617530 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G URI1 URI1 prefoldin like chaperone involved_in ISO (PMID:17936702) UniProt PMID:17936702 NCBI chr19:26,865,190...26,939,510
Ensembl chr19:35,601,872...35,694,273
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPIN1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551
JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPCAT1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (MGI:4460850|PMID:20018880) MGI PMID:20018880 MGI:4460850 NCBI chr 5:1,759,243...1,824,102
Ensembl chr 5:1,503,853...1,544,741
JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chr19:41,862,168...41,878,231 JBrowse link
negative regulation of phosphatidylinositol 3-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:19903888) UniProt PMID:19903888 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 involved_in ISO (PMID:17475214)
(MGI:3806716|PMID:18632611)
UniProt PMID:17475214 PMID:18632611 MGI:3806716 NCBI chr22:12,305,518...12,316,434
Ensembl chr22:30,141,326...30,152,397
JBrowse link
G RUBCN rubicon autophagy regulator involved_in ISO (PMID:21062745) UniProt PMID:21062745 NCBI chr 3:195,088,936...195,166,771
Ensembl chr 3:204,973,968...205,034,011
JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) UniProt PMID:21712384 MGI:5292318 NCBI chr 8:37,479,231...37,515,303
Ensembl chr 8:34,656,000...34,692,666
JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in ISO PMID:24201375
(PMID:24201375)
ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) UniProt PMID:19523918 NCBI chr19:16,956,000...16,993,429
Ensembl chr19:17,929,785...17,966,171
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOD1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) UniProt PMID:24157919 NCBI chr 5:168,951,787...168,960,934
Ensembl chr 5:175,857,814...175,866,951
JBrowse link
G CMYA5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) MGI PMID:21427212 MGI:5056263 NCBI chr 5:35,515,463...35,620,430
Ensembl chr 5:35,787,369...35,890,641
JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in ISO (PMID:9383998) UniProt PMID:9383998 NCBI chr11:45,801,504...45,837,357
Ensembl chr11:46,293,717...46,329,759
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869) BHF-UCL PMID:7592869 NCBI chr20:1,519,330...1,548,473 JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in ISO (PMID:7592869) BHF-UCL PMID:7592869 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082
JBrowse link
G MASTL microtubule associated serine/threonine kinase like involved_in ISO (PMID:20538976) UniProt PMID:20538976 NCBI chr10:27,264,475...27,296,085
Ensembl chr10:27,626,892...27,658,180
JBrowse link
G PPIA peptidylprolyl isomerase A ISO RGD PMID:19832699 RGD:7247324 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (PMID:11564868) ParkinsonsUK-UCL PMID:11564868 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B involved_in ISO (PMID:10807923) CAFA PMID:10807923 NCBI chr17:17,652,216...17,662,085
Ensembl chr17:17,868,965...17,878,120
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10585469 PMID:12016225 RGD:625568 RGD:9999389 NCBI chr17:44,224,007...44,240,906
Ensembl chr17:49,098,089...49,126,932
JBrowse link
G PPP4R4 protein phosphatase 4 regulatory subunit 4 acts_upstream_of_or_within ISO (PMID:18715871) MGI PMID:18715871 NCBI chr14:74,806,877...74,912,209
Ensembl chr14:94,139,654...94,244,712
JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) HGNC-UCL PMID:16916641 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G RGN regucalcin ISO RGD PMID:10922512 RGD:9590172 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 involved_in ISO (PMID:24709986) UniProt PMID:24709986 NCBI chr 7:67,973,316...68,024,986
Ensembl chr 7:82,446,562...82,497,769
JBrowse link
G TIPRL TOR signaling pathway regulator involved_in ISO (PMID:17384681) UniProt PMID:17384681 NCBI chr 1:143,666,013...143,689,490
Ensembl chr 1:147,391,890...147,415,425
JBrowse link
negative regulation of phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE2 ankyrin repeat and LEM domain containing 2 involved_in ISO (PMID:22770216) UniProt PMID:22770216 NCBI chr12:130,091,476...130,123,533
Ensembl chr12:134,805,830...134,835,140
JBrowse link
G ATXN1 ataxin 1 acts_upstream_of_or_within ISO (MGI:3774689|PMID:18216249) MGI PMID:18216249 MGI:3774689 NCBI chr 6:16,155,049...16,952,827
Ensembl chr 6:16,526,563...16,548,566
JBrowse link
G ATXN7 ataxin 7 acts_upstream_of_or_within ISO (MGI:3774689|PMID:18216249) MGI PMID:18216249 MGI:3774689 NCBI chr 3:63,766,480...63,906,913
Ensembl chr 3:65,194,703...65,280,879
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:19170105)
(MGI:3852291|PMID:19170105)
UniProt PMID:19170105 MGI:3852291 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:10208428), (PMID:8259215) BHF-UCL PMID:8259215 PMID:10208428 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B involved_in ISO (PMID:8078588) BHF-UCL PMID:8078588 NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr 1:50,214,767...50,221,465
Ensembl chr 1:51,704,528...51,718,374
JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:10208428) BHF-UCL PMID:10208428 NCBI chr19:10,118,302...10,120,957 JBrowse link
G DYNLL1 dynein light chain LC8-type 1 involved_in ISO (PMID:18579519) UniProt PMID:18579519 NCBI chr12:118,078,401...118,080,822
Ensembl chr12:121,452,118...121,454,550
JBrowse link
G GRB10 growth factor receptor bound protein 10 involved_in ISO (MGI:3847873|PMID:15664450) BHF-UCL PMID:15664450 MGI:3847873 NCBI chr 7:51,230,945...51,434,560
Ensembl chr 7:51,474,166...51,666,638
JBrowse link
G PRKRIP1 PRKR interacting protein 1 acts_upstream_of_or_within ISO (MGI:2665232|PMID:12679338) MGI PMID:12679338 MGI:2665232 NCBI chr 7:94,515,712...94,567,066
Ensembl chr13:24,723,062...24,734,122
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (MGI:6356246|PMID:30115939) UniProt PMID:30115939 MGI:6356246 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:17612497)
(MGI:5297784|PMID:17612497)
UniProt PMID:17612497 MGI:5297784 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) BHF-UCL PMID:19100238 MGI:3831067 NCBI chr 4:56,442,773...56,491,148
Ensembl chr 4:62,836,288...62,882,570
JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO (MGI:6356246|PMID:30115939) UniProt PMID:30115939 MGI:6356246 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545
JBrowse link
negative regulation of protein autophosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:12070119) UniProt PMID:12070119 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G ENG endoglin involved_in ISO (PMID:12015308) BHF-UCL PMID:12015308 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:11289049) BHF-UCL PMID:11289049 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO (PMID:18046415) UniProt PMID:18046415 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674
JBrowse link
G GFRA2 GDNF family receptor alpha 2 ISO RGD PMID:9608533 RGD:632689 NCBI chr 8:20,935,512...21,033,571
Ensembl chr 8:17,878,102...17,974,457
JBrowse link
G IMPACT impact RWD domain protein involved_in ISO (MGI:5576818|PMID:24333428)
(MGI:5494763|PMID:23447528)
UniProt PMID:23447528 PMID:24333428 MGI:5494763 MGI:5576818 NCBI chr18:17,678,297...17,720,348
Ensembl chr18:21,299,213...21,322,868
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:3662941|PMID:16916642) MGI PMID:16916642 MGI:3662941 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G NLRP12 NLR family pyrin domain containing 12 involved_in ISO (PMID:16203735) HGNC-UCL PMID:16203735 NCBI chr19:50,735,124...50,765,556
Ensembl chr19:59,582,005...59,614,436
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277) MGI PMID:7499277 PMID:8175795 MGI:65996 MGI:77358 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO PMID:18216281 ARUK-UCL PMID:18216281 RGD:13461749 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545
JBrowse link
negative regulation of protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO NFATc3 RGD PMID:19358331 RGD:2312604 NCBI chr17:51,162,993...51,199,202
Ensembl chr17:56,023,381...56,058,744
JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in ISO (MGI:4457251|PMID:17438131), (MGI:4457259|PMID:9792806) UniProt PMID:9792806 PMID:17438131 MGI:4457251 MGI:4457259 NCBI chr  X:59,401,426...59,434,363
Ensembl chr  X:69,460,734...69,493,616
JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (PMID:11564868) ParkinsonsUK-UCL PMID:11564868 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in ISO (PMID:21466834) GO_Central PMID:21466834 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) HGNC-UCL PMID:16916641 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta involved_in ISO (PMID:17255105) BHF-UCL PMID:17255105 NCBI chr20:41,216,071...41,238,893
Ensembl chr20:42,309,155...42,331,695
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon acts_upstream_of_or_within ISO (MGI:2665158|PMID:12796778) MGI PMID:12796778 MGI:2665158 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189
JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:9373175)
PMID:8524413
BHF-UCL PMID:8524413 PMID:9373175 RGD:8554844 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G AKT1S1 AKT1 substrate 1 involved_in ISO (PMID:17386266) UniProt PMID:17386266 NCBI chr19:46,882,073...46,890,404
Ensembl chr19:55,797,927...55,806,256
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 involved_in ISO (PMID:18305109) UniProt PMID:18305109 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600
JBrowse link
G CAV3 caveolin 3 acts_upstream_of_or_within ISO (MGI:2682500|PMID:14600260) MGI PMID:14600260 MGI:2682500 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:15582998) BHF-UCL PMID:15582998 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:5478702|PMID:22496641) UniProt PMID:22496641 MGI:5478702 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G CEP43 centrosomal protein 43 involved_in ISO (PMID:17888034) UniProt PMID:17888034 NCBI chr 6:164,969,391...165,011,935
Ensembl chr 6:169,945,218...169,988,027
JBrowse link
G CEP85 centrosomal protein 85 involved_in ISO (PMID:26220856) UniProt PMID:26220856 NCBI chr 1:25,495,228...25,539,857
Ensembl chr 1:26,562,744...26,607,852
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G DBNDD2 dysbindin domain containing 2 involved_in ISO (PMID:16618118) UniProt PMID:16618118 NCBI chr20:41,738,913...41,743,520
Ensembl chr20:42,829,178...42,833,333
JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein involved_in ISO (PMID:19446321) UniProt PMID:19446321 NCBI chr 8:116,563,935...116,743,843
Ensembl chr 8:119,311,942...119,492,127
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:15601829) UniProt PMID:15601829 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786
JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:12688394 RGD:1581394 NCBI chr 4:4,189,536...4,193,144
Ensembl chr 4:9,509,094...9,510,527
JBrowse link
G DUSP19 dual specificity phosphatase 19 involved_in ISO (MGI:2182169|PMID:11959862) BHF-UCL PMID:11959862 MGI:2182169 NCBI chr2B:70,347,712...70,371,852
Ensembl chr2B:188,157,061...188,178,266
JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in ISO (PMID:10330181) BHF-UCL PMID:10330181 NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008
JBrowse link
G EPHA1 EPH receptor A1 involved_in ISO (PMID:19118217) UniProt PMID:19118217 NCBI chr 7:135,385,894...135,403,632
Ensembl chr 7:147,875,363...147,892,745
JBrowse link
G EPHB2 EPH receptor B2 acts_upstream_of ISO (MGI:5905277|PMID:11585923) ARUK-UCL PMID:11585923 MGI:5905277 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118
JBrowse link
G FABP4 fatty acid binding protein 4 acts_upstream_of_or_within ISO (MGI:3578695|PMID:15684432) MGI PMID:15684432 MGI:3578695 NCBI chr 8:78,001,476...78,006,006
Ensembl chr 8:79,624,899...79,630,168
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr19:1,489,263...1,491,391
Ensembl chr19:2,451,837...2,453,992
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma acts_upstream_of_or_within ISO (MGI:2384369|PMID:12124778) MGI PMID:12124778 MGI:2384369 NCBI chr 9:60,695,307...60,696,860
Ensembl chr 9:88,740,411...88,741,958
JBrowse link
G GNAQ G protein subunit alpha q involved_in ISO (PMID:20399743) BHF-UCL PMID:20399743 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849
JBrowse link
G GSKIP GSK3B interacting protein involved_in ISO (PMID:16981698) UniProt PMID:16981698 NCBI chr14:76,993,055...77,017,142
Ensembl chr14:96,329,936...96,339,378
JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD
BHF-UCL
PMID:16636664 PMID:21668448 RGD:10401931 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 involved_in ISO (MGI:3581090|PMID:15731106) BHF-UCL PMID:15731106 MGI:3581090 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984
JBrowse link
G IL6 interleukin 6 ISO Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ILK integrin linked kinase ISO GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155
JBrowse link
G LRP6 LDL receptor related protein 6 involved_in ISO (PMID:16365045) BHF-UCL PMID:16365045 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G MLLT1 MLLT1 super elongation complex subunit acts_upstream_of_or_within ISO (MGI:1891804|PMID:11007757) MGI PMID:11007757 MGI:1891804 NCBI chr19:5,231,481...5,301,160
Ensembl chr19:6,156,365...6,216,779
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:3689489|PMID:17053831)
(MGI:3655425|PMID:16835260)
MGI PMID:16835260 PMID:17053831 MGI:3655425 MGI:3689489 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NF2 neurofibromin 2 acts_upstream_of_or_within ISO (MGI:2679135|PMID:14580336)
(MGI:3613261|PMID:16405865)
MGI PMID:14580336 PMID:16405865 MGI:2679135 MGI:3613261 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) ParkinsonsUK-UCL PMID:15983381 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
G PCP4 Purkinje cell protein 4 ISO RGD PMID:10751438 RGD:1579763 NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:9373175) BHF-UCL PMID:9373175 NCBI chr16:1,394,447...1,463,735 JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (MGI:894256|PMID:9218452) MGI PMID:9218452 MGI:894256 NCBI chr 8:75,046,316...75,136,264
Ensembl chr 8:76,734,210...76,766,673
JBrowse link
G PKIG cAMP-dependent protein kinase inhibitor gamma acts_upstream_of_or_within ISO (MGI:894256|PMID:9218452) MGI PMID:9218452 MGI:894256 NCBI chr20:40,861,694...40,949,756
Ensembl chr20:42,039,676...42,049,064
JBrowse link
G PKN1 protein kinase N1 acts_upstream_of_or_within ISO (MGI:5467878|PMID:23223530) MGI PMID:23223530 MGI:5467878 NCBI chr19:13,996,454...14,035,272
Ensembl chr19:14,846,463...14,879,205
JBrowse link
G PLEC plectin involved_in ISO (MGI:2386377|PMID:12200133) MGI PMID:12200133 MGI:2386377 NCBI chr 8:140,681,252...140,742,753
Ensembl chr 8:143,674,696...143,712,433
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E involved_in ISO (PMID:11864573) UniProt PMID:11864573 NCBI chr17:52,832,291...53,057,157
Ensembl chr17:57,874,629...57,903,205
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:11864573) UniProt PMID:11864573 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in ISO (PMID:17255938) BHF-UCL PMID:17255938 NCBI chr 7:143,143,556...143,463,492
Ensembl chr 7:155,293,748...155,610,078
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO (MGI:3821563|PMID:18316483) MGI PMID:18316483 MGI:3821563 NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943
JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (MGI:2677557|PMID:11923480) MGI PMID:11923480 MGI:2677557 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903
JBrowse link
G PRKRIP1 PRKR interacting protein 1 acts_upstream_of_or_within ISO (MGI:2665232|PMID:12679338) MGI PMID:12679338 MGI:2665232 NCBI chr 7:94,515,712...94,567,066
Ensembl chr13:24,723,062...24,734,122
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (MGI:2664026|PMID:12805290) MGI PMID:12805290 MGI:2664026 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (PMID:9197241)
(MGI:1889764|PMID:10970857)
UniProt PMID:9197241 PMID:10970857 MGI:1889764 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G PYDC1 pyrin domain containing 1 involved_in ISO (PMID:12656673) HGNC-UCL PMID:12656673 NCBI chr16:23,748,695...23,750,461
Ensembl chr16:31,588,129...31,588,398
JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:11096076) CAFA PMID:11096076 NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO (PMID:9858607) UniProt PMID:9858607 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G RGN regucalcin ISO RGD PMID:11455566 RGD:9590207 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G RTRAF RNA transcription, translation and transport factor involved_in ISO (PMID:15147888) UniProt PMID:15147888 NCBI chr14:32,589,078...32,604,286
Ensembl chr14:50,874,274...50,889,493
JBrowse link
G SH3BP5 SH3 domain binding protein 5 involved_in ISO (MGI:1337389|PMID:10339589) UniProt PMID:10339589 MGI:1337389 NCBI chr 3:15,180,369...15,257,951
Ensembl chr 3:15,517,447...15,594,971
JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (MGI:5527493|PMID:23528453) MGI PMID:23528453 MGI:5527493 NCBI chr 9:37,768,566...37,921,897 JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit involved_in ISO (PMID:28195531) HGNC PMID:28195531 NCBI chr17:32,858,205...32,871,132
Ensembl chr17:37,884,037...37,896,972
JBrowse link
G SMYD3 SET and MYND domain containing 3 acts_upstream_of_or_within ISO (MGI:5500979|PMID:23752591) MGI PMID:23752591 MGI:5500979 NCBI chr 1:221,371,348...222,125,774
Ensembl chr 1:226,737,960...227,481,191
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in ISO (PMID:18216281) ARUK-UCL PMID:18216281 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565
JBrowse link
G TAF7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:18391197) UniProt PMID:18391197 NCBI chr 5:136,680,554...136,682,862 JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO PMID:15093746 UniProt PMID:15093746 RGD:8553684 NCBI chr11:114,253,535...114,259,495
Ensembl chr11:118,180,717...118,186,901
JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (PMID:15299019) BHF-UCL PMID:15299019 NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924
JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in ISO (PMID:12791994)
(MGI:3687885|PMID:12791994)
BHF-UCL
UniProt
PMID:12791994 MGI:3687885 NCBI chr20:583,267...605,416
Ensembl chr20:359,879...375,486
JBrowse link
G TRIM27 tripartite motif containing 27 involved_in ISO (PMID:22128329) UniProt PMID:22128329 NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308
JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (MGI:3050929|PMID:15249583) MGI PMID:15249583 MGI:3050929 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042)
(MGI:5811934|PMID:27609517)
MGI PMID:20585042 PMID:27609517 MGI:4838721 MGI:5811934 NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133
JBrowse link
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in ISO (PMID:22504299) CAFA PMID:22504299 NCBI chr14:80,954,852...80,996,316
Ensembl chr14:100,268,845...100,310,662
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in ISO (PMID:20412773) BHF-UCL PMID:20412773 NCBI chr 3:146,536,564...146,678,847
Ensembl chr 3:154,114,034...154,254,490
JBrowse link
negative regulation of protein kinase activity by regulation of protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in ISO (PMID:18362360)
(MGI:5447606|PMID:18362360)
(PMID:19651874)
UniProt PMID:18362360 PMID:19651874 MGI:5447606 NCBI chr 1:129,937,993...129,983,747 JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 involved_in ISO (PMID:21289159) UniProt PMID:21289159 NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:21283629) UniProt PMID:21283629 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CORO1C coronin 1C involved_in ISO (PMID:19913511) UniProt PMID:19913511 NCBI chr12:106,220,755...106,306,098
Ensembl chr12:109,617,093...109,674,368
JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO (MGI:5532582|PMID:23977283) MGI PMID:23977283 MGI:5532582 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720
JBrowse link
G DUSP26 dual specificity phosphatase 26 involved_in ISO (PMID:15796912) UniProt PMID:15796912 NCBI chr 8:32,906,182...32,915,015
Ensembl chr 8:30,091,092...30,100,699
JBrowse link
G NPM1 nucleophosmin 1 involved_in ISO (PMID:12882984) UniProt PMID:12882984 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in ISO (PMID:15140879) UniProt PMID:15140879 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
negative regulation of protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO Smad2 RGD PMID:21743278 RGD:7243870 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G ANGPT1 angiopoietin 1 acts_upstream_of_or_within ISO (MGI:4437182|PMID:20060382) MGI PMID:20060382 MGI:4437182 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783
JBrowse link
G ARRB1 arrestin beta 1 ISO ERK RGD PMID:19254952 RGD:5509898 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155
JBrowse link
G ARRB2 arrestin beta 2 involved_in ISO (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G ATG14 autophagy related 14 involved_in ISO (MGI:5619439|PMID:23332761) UniProt PMID:23332761 MGI:5619439 NCBI chr14:35,953,228...35,998,650
Ensembl chr14:54,226,720...54,272,018
JBrowse link
G BAG1 BAG cochaperone 1 acts_upstream_of_or_within ISO (MGI:3603966|PMID:16116448) MGI PMID:16116448 MGI:3603966 NCBI chr 9:33,033,267...33,043,013
Ensembl chr 9:33,841,449...33,851,167
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO inhibition increases phosphorylation of ERK, p38, JNK and Thr495 of eNOS in SHR-SP rats RGD PMID:16497153 RGD:1625749 NCBI chr14:76,885,923...76,894,456 JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit involved_in ISO (PMID:27723745)
(MGI:5818605|PMID:27723745)
UniProt PMID:27723745 MGI:5818605 NCBI chr 9:27,395,054...27,422,282
Ensembl chr 9:28,001,813...28,022,066
JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chr19:2,636,129...2,652,332
Ensembl chr19:3,586,983...3,601,990
JBrowse link
G CADM4 cell adhesion molecule 4 involved_in ISO (PMID:25893857)
(MGI:6271409|PMID:25893857)
UniProt PMID:25893857 MGI:6271409 NCBI chr19:40,564,288...40,581,830 JBrowse link
G CCNB1 cyclin B1 ISO MAPK RGD PMID:15291744 RGD:1578405 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CD109 CD109 molecule acts_upstream_of_or_within ISO (MGI:5441431|PMID:22490868) MGI PMID:22490868 MGI:5441431 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:17785205) UniProt PMID:17785205 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in ISO PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr15:20,172,874...20,223,382
Ensembl chr15:38,418,815...38,467,681
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO (MGI:3843740|PMID:19230830) ARUK-UCL PMID:19230830 MGI:3843740 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194
JBrowse link
G CIB1 calcium and integrin binding 1 involved_in ISO (MGI:5314162|PMID:22128142) UniProt PMID:22128142 MGI:5314162 NCBI chr15:68,919,377...68,923,213 JBrowse link
G CORO1C coronin 1C involved_in ISO (PMID:19913511) UniProt PMID:19913511 NCBI chr12:106,220,755...106,306,098
Ensembl chr12:109,617,093...109,674,368
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in ISO (PMID:23959425) ARUK-UCL PMID:23959425 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858
JBrowse link
G CTDSP1 CTD small phosphatase 1 acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) MGI PMID:22210897 MGI:5494382 NCBI chr2B:105,658,394...105,664,571
Ensembl chr2B:224,254,460...224,262,000
JBrowse link
G CTDSP2 CTD small phosphatase 2 acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) MGI PMID:22210897 MGI:5494382 NCBI chr12:31,079,686...31,106,789
Ensembl chr12:31,340,313...31,367,164
JBrowse link
G CTDSPL CTD small phosphatase like acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) MGI PMID:22210897 MGI:5494382 NCBI chr 3:37,761,101...37,883,330
Ensembl chr 3:38,127,971...38,166,485
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:20080667)
(MGI:3831615|PMID:19033661)
UniProt PMID:19033661 PMID:20080667 MGI:3831615 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 involved_in ISO (PMID:19122239) UniProt PMID:19122239 NCBI chr2B:69,991,321...70,059,693
Ensembl chr2B:187,799,532...187,864,496
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:26277342 RGD:11533440 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DUSP6 dual specificity phosphatase 6 acts_upstream_of_or_within ISO (MGI:3822592|PMID:18753132) MGI PMID:18753132 MGI:3822592 NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321
JBrowse link
G DVL1 dishevelled segment polarity protein 1 acts_upstream_of_or_within ISO (MGI:1095215|PMID:9271238) MGI PMID:9271238 MGI:1095215 NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008
JBrowse link
G EPHB2 EPH receptor B2 involved_in ISO (MGI:5905277|PMID:11585923) ARUK-UCL PMID:11585923 MGI:5905277 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118
JBrowse link
G FBLN1 fibulin 1 involved_in ISO (PMID:11792823) UniProt PMID:11792823 NCBI chr22:26,390,379...26,488,737
Ensembl chr22:44,582,843...44,666,011
JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in ISO (PMID:15733859) CAFA PMID:15733859 NCBI chr19:18,009,505...18,021,772
Ensembl chr19:18,980,269...18,992,170
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO Nfkbia RGD PMID:17473852 RGD:5688754 NCBI chr 5:128,463,186...128,517,563
Ensembl chr 5:134,619,076...134,673,658
JBrowse link
G IBTK inhibitor of Bruton tyrosine kinase acts_upstream_of_or_within ISO (PMID:11577348) MGI PMID:11577348 NCBI chr 6:80,061,649...80,139,393
Ensembl chr 6:83,325,428...83,402,670
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 acts_upstream_of_or_within ISO (PMID:17591901) MGI PMID:17591901 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IL2 interleukin 2 ISO RGD PMID:3124825 RGD:1600106 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IMPACT impact RWD domain protein acts_upstream_of_or_within
involved_in
ISO (MGI:3589702|PMID:15937339)
(MGI:5576818|PMID:24333428)
(MGI:5494763|PMID:23447528)
MGI
UniProt
PMID:15937339 PMID:23447528 PMID:24333428 MGI:3589702 MGI:5494763 MGI:5576818 NCBI chr18:17,678,297...17,720,348
Ensembl chr18:21,299,213...21,322,868
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in ISO (MGI:5299272|PMID:21938401) UniProt PMID:21938401 MGI:5299272 NCBI chr17:1,477,511...1,499,765
Ensembl chr17:1,377,312...1,399,373
JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISO (PMID:19124461) UniProt PMID:19124461 NCBI chr20:20,317,060...20,320,051 JBrowse link
G INSR insulin receptor ISO Stat3 in hypothalamus RGD PMID:17585961 RGD:2290473 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G KIRREL1 kirre like nephrin family adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:4950838|PMID:21306299) MGI PMID:21306299 MGI:4950838 NCBI chr 1:133,363,880...133,465,717
Ensembl chr 1:137,233,701...137,255,927
JBrowse link
G KIRREL2 kirre like nephrin family adhesion molecule 2 acts_upstream_of_or_within ISO (MGI:4950838|PMID:21306299) MGI PMID:21306299 MGI:4950838 NCBI chr19:32,769,592...32,785,045
Ensembl chr19:41,518,306...41,533,467
JBrowse link
G KLHL31 kelch like family member 31 involved_in ISO (PMID:18719355) UniProt PMID:18719355 NCBI chr 6:53,201,483...53,351,320
Ensembl chr 6:54,839,066...54,893,640
JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor acts_upstream_of_or_within ISO (MGI:3620385|PMID:16533754) MGI PMID:16533754 MGI:3620385 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446
JBrowse link
G LRP6 LDL receptor related protein 6 involved_in ISO (PMID:16365045) BHF-UCL PMID:16365045 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in ISO (MGI:5553024|PMID:24464040) ParkinsonsUK-UCL PMID:24464040 MGI:5553024 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:2687173|PMID:14525964) UniProt PMID:14525964 MGI:2687173 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287
JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO ERK1/ERK2 RGD PMID:15951342 RGD:1581938 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393
JBrowse link
G MEN1 menin 1 involved_in ISO (PMID:12226747) UniProt PMID:12226747 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 involved_in ISO (MGI:5142343|PMID:21730291) UniProt PMID:21730291 MGI:5142343 NCBI chr 6:107,247,084...107,269,138
Ensembl chr 6:111,295,548...111,317,214
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:21357504 RGD:10041003 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MYADM myeloid associated differentiation marker involved_in ISO (PMID:23264465) UniProt PMID:23264465 NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758
JBrowse link
G NIBAN1 niban apoptosis regulator 1 involved_in ISO (MGI:3716265|PMID:17588536) UniProt PMID:17588536 MGI:3716265 NCBI chr 1:160,320,707...160,497,649
Ensembl chr 1:164,479,202...164,581,494
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chr 5:66,662,249...66,772,352
Ensembl chr 5:71,719,257...71,823,242
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) BHF-UCL PMID:23027130 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204
JBrowse link
G OCLN occludin involved_in ISO (PMID:28718701) ARUK-UCL PMID:28718701 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO Mapk1, Mapk3 RGD PMID:21712532 RGD:9590189 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921
JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (MGI:3722998|PMID:17724343)
(PMID:17724343)
MGI PMID:17724343 MGI:3722998 NCBI chr 4:45,255,403...45,279,319
Ensembl chr 4:51,102,305...51,123,506
JBrowse link
G PARD6A par-6 family cell polarity regulator alpha acts_upstream_of_or_within ISO (MGI:5529726|PMID:24305805) MGI PMID:24305805 MGI:5529726 NCBI chr16:48,004,822...48,006,656
Ensembl chr16:67,394,252...67,395,991
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) ParkinsonsUK-UCL PMID:15983381 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within ISO (MGI:3622497|PMID:16497297) MGI PMID:16497297 MGI:3622497 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474
JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within ISO (MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:5293269 NCBI chr 8:27,084,789...27,112,986
Ensembl chr 8:24,285,395...24,313,658
JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:15886202 RGD:1580668 NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:19079291) BHF-UCL PMID:19079291 NCBI chr2B:116,265,529...116,517,557 JBrowse link
G PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase like 1 involved_in ISO (PMID:19680787) ARUK-UCL PMID:19680787 NCBI chr 9:99,041,687...99,051,031
Ensembl chr 9:127,712,944...127,722,332
JBrowse link
G PKN1 protein kinase N1 acts_upstream_of_or_within ISO (MGI:5467878|PMID:23223530) MGI PMID:23223530 MGI:5467878 NCBI chr19:13,996,454...14,035,272
Ensembl chr19:14,846,463...14,879,205
JBrowse link
G PLPP3 phospholipid phosphatase 3 involved_in ISO (PMID:20123964)
(MGI:4820698|PMID:20123964)
BHF-UCL PMID:20123964 MGI:4820698 NCBI chr 1:55,779,343...55,862,717
Ensembl chr 1:57,489,178...57,573,398
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO Mapk1, Mapk3 RGD PMID:19786068 RGD:10059654 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISO (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B involved_in ISO (PMID:26307080) UniProt PMID:26307080 NCBI chr 1:180,002,895...180,014,956
Ensembl chr 1:184,293,640...184,302,316
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO AMPK alpha RGD PMID:18832448 PMID:26732138 RGD:11572421 RGD:8693393 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit ISO Mapk1, Mapk3, Mapk8, Mapk9 RGD PMID:19686245 RGD:8693743 NCBI chr19:43,329,680...43,373,282
Ensembl chr19:51,865,317...51,909,027
JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (MGI:5529726|PMID:24305805)
(MGI:3033566|PMID:14966518)
MGI PMID:14966518 PMID:24305805 MGI:3033566 MGI:5529726 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISO (MGI:5554971|PMID:24158435) UniProt PMID:24158435 MGI:5554971 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:17512523) BHF-UCL PMID:17512523 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G PRNP prion protein involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chr20:4,713,616...4,728,847
Ensembl chr20:4,523,155...4,523,916
JBrowse link
G PRR5L proline rich 5 like involved_in ISO (PMID:22609986) UniProt PMID:22609986 NCBI chr11:36,269,291...36,438,954
Ensembl chr11:36,223,385...36,311,659
JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3044464|PMID:15148382) MGI PMID:15148382 MGI:3044464 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:20123964)
(MGI:5693365|PMID:19147652)
BHF-UCL PMID:19147652 PMID:20123964 MGI:5693365 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 involved_in ISO (PMID:25893857) UniProt PMID:25893857 NCBI chr 4:78,893,598...79,118,745
Ensembl chr 4:89,623,271...89,847,616
JBrowse link
G RGN regucalcin ISO RGD PMID:9827702 RGD:9590180 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chr 9:17,386,298...17,605,722
Ensembl chr 9:18,045,198...18,097,579
JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO (PMID:18345009) UniProt PMID:18345009 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
G SNCA synuclein alpha involved_in ISO PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
G SPAG9 sperm associated antigen 9 ISO RGD PMID:19959466 RGD:30296662 NCBI chr17:45,053,292...45,211,488
Ensembl chr17:49,924,650...50,081,918
JBrowse link
G STK39 serine/threonine kinase 39 acts_upstream_of_or_within ISO (MGI:5292405|PMID:21907141) MGI PMID:21907141 MGI:5292405 NCBI chr2B:55,204,203...55,501,033
Ensembl chr2B:172,674,514...172,970,063
JBrowse link
G TARDBP TAR DNA binding protein involved_in ISO (PMID:18305152) CACAO PMID:18305152 NCBI chr 1:9,775,084...9,786,710
Ensembl chr 1:10,996,006...11,008,732
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:8053900) BHF-UCL PMID:8053900 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 involved_in ISO (PMID:22079989) CACAO PMID:22079989 NCBI chr2B:125,558,537...125,637,733
Ensembl chr2B:244,405,992...244,481,785
JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:18056446 RGD:11568676 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in ISO (PMID:22504299) CAFA PMID:22504299 NCBI chr14:80,954,852...80,996,316
Ensembl chr14:100,268,845...100,310,662
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in ISO (PMID:20412773) BHF-UCL PMID:20412773 NCBI chr 3:146,536,564...146,678,847
Ensembl chr 3:154,114,034...154,254,490
JBrowse link
G XDH xanthine dehydrogenase involved_in ISO (PMID:18386220) UniProt PMID:18386220 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
G ZBED3 zinc finger BED-type containing 3 acts_upstream_of_or_within ISO (MGI:3844787|PMID:19141611) MGI PMID:19141611 MGI:3844787 NCBI chr 5:38,214,260...38,229,373 JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (MGI:5297619|PMID:21971051) UniProt PMID:21971051 MGI:5297619 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
G ZNF416 zinc finger protein 416 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) MGI PMID:29065170 MGI:5920524 NCBI chr19:54,583,428...54,590,792
Ensembl chr19:63,412,869...63,420,231
JBrowse link
negative regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:11121037) BHF-UCL PMID:11121037 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:19223857) UniProt PMID:19223857 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (PMID:20154697)
(MGI:4398763|PMID:19903888)
(PMID:19903888)
BHF-UCL
UniProt
PMID:19903888 PMID:20154697 MGI:4398763 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G DTNBP1 dystrobrevin binding protein 1 acts_upstream_of_or_within ISO (MGI:5609072|PMID:25297099) MGI PMID:25297099 MGI:5609072 NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in ISO (PMID:23329839) CACAO PMID:23329839 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G LOC100974858 core histone macro-H2A.1 involved_in ISO (PMID:22194607) UniProt PMID:22194607 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834
JBrowse link
G LRP5 LDL receptor related protein 5 involved_in ISO (PMID:19107203) BHF-UCL PMID:19107203 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G LRP6 LDL receptor related protein 6 involved_in ISO (PMID:19107203) BHF-UCL PMID:19107203 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:12486103) UniProt PMID:12486103 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G SLC8A1 solute carrier family 8 member A1 acts_upstream_of_or_within ISO (MGI:6282180|PMID:29274751) ARUK-UCL PMID:29274751 MGI:6282180 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038
JBrowse link
G SLC8A3 solute carrier family 8 member A3 acts_upstream_of_or_within ISO (MGI:6282180|PMID:29274751) ARUK-UCL PMID:29274751 MGI:6282180 NCBI chr14:50,634,091...50,779,712 JBrowse link
G TESK1 testis associated actin remodelling kinase 1 involved_in ISO PMID:18216281 ARUK-UCL PMID:18216281 RGD:13461749 NCBI chr 9:35,456,965...35,461,736
Ensembl chr 9:36,258,902...36,264,545
JBrowse link
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R14D protein phosphatase 1 regulatory inhibitor subunit 14D involved_in ISO (PMID:12974676) UniProt PMID:12974676 NCBI chr15:19,756,077...19,786,920
Ensembl chr15:38,007,632...38,022,094
JBrowse link
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in ISO (PMID:25006397)
(MGI:5607357|PMID:25017399)
BHF-UCL PMID:25006397 PMID:25017399 MGI:5607357 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (MGI:5779255|PMID:26764350) MGI PMID:26764350 MGI:5779255 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055
JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551
JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:9151699)
(PMID:16493035)
ARUK-UCL PMID:9151699 PMID:16493035 NCBI chr19:51,606,681...51,612,751 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) UniProt PMID:15539407 Ensembl chr20:61,453,386...61,462,951 JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5619464|PMID:21216966) ParkinsonsUK-UCL PMID:21216966 MGI:5619464 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3530407|PMID:15661907) ARUK-UCL PMID:15661907 MGI:3530407 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 involved_in ISO (PMID:17525734) UniProt PMID:17525734 NCBI chr17:18,666,094...18,742,015
Ensembl chr17:18,942,084...19,015,744
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO PMID:22479590 UniProt PMID:22479590 RGD:12793046 NCBI chr11:114,253,535...114,259,495
Ensembl chr11:118,180,717...118,186,901
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:11500506 RGD:13508599 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988
JBrowse link
G MGAT5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:24846175) ARUK-UCL PMID:24846175 NCBI chr2B:25,394,435...25,724,420
Ensembl chr2B:138,344,539...138,538,857
JBrowse link
negative regulation of Rho-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHORDC1 cysteine and histidine rich domain containing 1 involved_in ISO (MGI:4441223|PMID:20230755) UniProt PMID:20230755 MGI:4441223 NCBI chr11:85,170,779...85,193,659
Ensembl chr11:88,668,179...88,689,378
JBrowse link
G HEG1 heart development protein with EGF like domains 1 involved_in ISO (PMID:26780829) UniProt PMID:26780829 NCBI chr 3:122,091,832...122,204,436
Ensembl chr 3:128,969,817...129,028,317
JBrowse link
G RASIP1 Ras interacting protein 1 involved_in ISO (PMID:26780829) UniProt PMID:26780829 NCBI chr19:45,720,179...45,740,131 JBrowse link
negative regulation of tau-protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in ISO (PMID:19808651) ARUK-UCL PMID:19808651 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G SORL1 sortilin related receptor 1 involved_in ISO (MGI:5569468|PMID:22986780) Alzheimers_University_of_Toronto PMID:22986780 MGI:5569468 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432
JBrowse link
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (MGI:3703676|PMID:12388746) MGI PMID:12388746 MGI:3703676 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (MGI:5779255|PMID:26764350) MGI PMID:26764350 MGI:5779255 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO STAT5b RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536
JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F involved_in ISO (PMID:25476455) UniProt PMID:25476455 NCBI chr10:116,295,802...116,396,764
Ensembl chr10:119,712,696...119,813,444
JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:20980260 RGD:5128774 NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035
JBrowse link
G NF2 neurofibromin 2 involved_in ISO (PMID:12444102) HGNC-UCL PMID:12444102 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013
JBrowse link
G PARP14 poly(ADP-ribose) polymerase family member 14 involved_in ISO (PMID:27796300) UniProt PMID:27796300 NCBI chr 3:119,773,334...119,823,732
Ensembl chr 3:126,677,868...126,728,256
JBrowse link
G PIBF1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) UniProt PMID:16393965 NCBI chr13:54,011,239...54,247,952
Ensembl chr13:72,788,608...73,022,473
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in
NOT|involved_in
ISO (PMID:12138178), (PMID:17210636)
(MGI:5493214|PMID:17210636)
(PMID:12359225)
UniProt PMID:12138178 PMID:12359225 PMID:17210636 MGI:5493214 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in ISO (MGI:3510267|PMID:15337790) ARUK-UCL PMID:15337790 MGI:3510267 NCBI chr12:108,977,344...109,024,029 JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25019494)
(MGI:1098503|PMID:9202127)
BHF-UCL
MGI
PMID:9202127 PMID:25019494 MGI:1098503 NCBI chr16:10,196,432...10,198,205 JBrowse link
G SOCS3 suppressor of cytokine signaling 3 involved_in ISO (PMID:25019494) BHF-UCL PMID:25019494 NCBI chr17:72,433,206...72,436,500
Ensembl chr17:77,983,389...77,984,066
JBrowse link
G SUZ12 SUZ12 polycomb repressive complex 2 subunit ISO RGD PMID:23192652 RGD:9586745 NCBI chr17:24,790,921...24,853,790 JBrowse link
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in ISO (PMID:15219672) UniProt PMID:15219672 NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909
JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in ISO (PMID:10391943) BHF-UCL PMID:10391943 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720
JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in ISO (MGI:6101044|PMID:28759036) BHF-UCL PMID:28759036 MGI:6101044 NCBI chr17:13,618,860...13,631,743
Ensembl chr17:13,784,594...13,797,045
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (MGI:5490930|PMID:23639442) BHF-UCL PMID:23639442 MGI:5490930 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B involved_in ISO (MGI:6379079|PMID:26063811) CACAO PMID:26063811 MGI:6379079 NCBI chr12:68,025,973...68,147,613
Ensembl chr12:70,797,843...70,915,308
JBrowse link
G PTPRH protein tyrosine phosphatase receptor type H involved_in ISO (MGI:6379079|PMID:26063811) CACAO PMID:26063811 MGI:6379079 NCBI chr19:52,221,813...52,249,218
Ensembl chr19:60,917,749...60,943,528
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (MGI:6379079|PMID:26063811) CACAO PMID:26063811 MGI:6379079 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O involved_in ISO (MGI:6379079|PMID:26063811) CACAO PMID:26063811 MGI:6379079 NCBI chr12:15,329,314...15,594,787
Ensembl chr12:15,725,917...15,990,532
JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T involved_in ISO (PMID:24846175) ARUK-UCL PMID:24846175 NCBI chr20:38,399,267...39,526,776
Ensembl chr20:39,502,794...40,317,701
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12654
    metabolic process 7926
      cellular metabolic process 7262
        negative regulation of cellular metabolic process 2178
          negative regulation of phosphorus metabolic process 431
            negative regulation of phosphate metabolic process 431
              negative regulation of dephosphorylation + 42
              negative regulation of inositol phosphate biosynthetic process + 2
              negative regulation of nucleotide metabolic process + 24
              negative regulation of pentose-phosphate shunt 1
              negative regulation of phospholipid metabolic process + 7
              negative regulation of phosphorylation + 382
              negative regulation of sarcinapterin metabolic process + 0
              negative regulation of thiamine diphosphate biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 12654
    biological regulation 9217
      regulation of biological process 8711
        regulation of cellular process 8237
          regulation of cellular metabolic process 4546
            negative regulation of cellular metabolic process 2178
              negative regulation of phosphorus metabolic process 431
                negative regulation of phosphate metabolic process 431
                  negative regulation of dephosphorylation + 42
                  negative regulation of inositol phosphate biosynthetic process + 2
                  negative regulation of nucleotide metabolic process + 24
                  negative regulation of pentose-phosphate shunt 1
                  negative regulation of phospholipid metabolic process + 7
                  negative regulation of phosphorylation + 382
                  negative regulation of sarcinapterin metabolic process + 0
                  negative regulation of thiamine diphosphate biosynthetic process 0
paths to the root