Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nucleobase-containing compound metabolic process
go back to main search page
Accession:GO:0045935 term browser browse the term
Definition:Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
Synonyms:exact_synonym: positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism;   up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;   upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
 narrow_synonym: activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;   stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
 related_synonym: positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process


show annotations for term's descendants           Sort by:
 
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPEB3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:26489465) UniProt PMID:26489465 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G DND1 DND microRNA-mediated repression inhibitor 1 involved_in ISO (PMID:28297718) CACAO PMID:28297718 NCBI chr 5:136,035,464...136,038,524
Ensembl chr 5:142,151,441...142,154,262
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO RGD PMID:20805360 RGD:10042974 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
G KHSRP KH-type splicing regulatory protein involved_in ISO (PMID:16126846)
(PMID:28275056)
UniProt
CACAO
PMID:16126846 PMID:28275056 NCBI chr19:5,433,989...5,445,721 JBrowse link
G MOV10 Mov10 RISC complex RNA helicase involved_in ISO (PMID:24726324) UniProt PMID:24726324 NCBI chr 1:115,327,051...115,353,483
Ensembl chr 1:124,999,353...125,025,820
JBrowse link
G PLEKHN1 pleckstrin homology domain containing N1 involved_in ISO (PMID:29180010)
(MGI:6105829|PMID:27616329)
UniProt PMID:27616329 PMID:29180010 MGI:6105829 Ensembl chr 1:865,290...873,575 JBrowse link
G QKI QKI, KH domain containing RNA binding acts_upstream_of_or_within ISO (MGI:5316962|PMID:20631256) MGI PMID:20631256 MGI:5316962 NCBI chr 6:161,361,413...161,523,414 JBrowse link
G RBM24 RNA binding motif protein 24 involved_in ISO (PMID:24375645) UniProt PMID:24375645 NCBI chr 6:17,140,450...17,153,035 JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5706859|PMID:26000482), (MGI:5751631|PMID:26255671) UniProt PMID:26000482 PMID:26255671 MGI:5706859 MGI:5751631 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G TARDBP TAR DNA binding protein involved_in ISO (PMID:28335005) CACAO PMID:28335005 NCBI chr 1:9,775,084...9,786,710
Ensembl chr 1:10,996,006...11,008,732
JBrowse link
G TRIM71 tripartite motif containing 71 involved_in ISO (PMID:23125361) CACAO PMID:23125361 NCBI chr 3:32,745,217...32,824,985
Ensembl chr 3:33,050,997...33,123,910
JBrowse link
G UPF1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:26255671)
(PMID:24726324)
UniProt PMID:24726324 PMID:26255671 NCBI chr19:18,269,878...18,306,199
Ensembl chr19:19,292,725...19,313,224
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (PMID:19909337)
(MGI:3842851|PMID:19322177), (MGI:5706859|PMID:26000482), (MGI:5706909|PMID:23185455), (MGI:5707103|PMID:26134560), (MGI:5751631|PMID:26255671)
UniProt PMID:19322177 PMID:19909337 PMID:23185455 PMID:26000482 PMID:26134560 PMID:26255671 MGI:3842851 MGI:5706859 MGI:5706909 MGI:5707103 MGI:5751631 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D involved_in ISO (MGI:5707103|PMID:26134560) UniProt PMID:26134560 MGI:5707103 NCBI chr 6:147,266,039...147,304,289
Ensembl chr 6:151,974,485...151,999,898
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in ISO (PMID:11719186), (PMID:15687258), (PMID:20221403), (PMID:27193233), (PMID:9703499)
(MGI:5784976|PMID:22701344), (MGI:5788345|PMID:27193233)
(MGI:5795824|PMID:17288565)
(PMID:14679154), (PMID:15187101), (PMID:15634918), (PMID:15766526)
UniProt PMID:9703499 PMID:11719186 PMID:14679154 PMID:15187101 PMID:15634918 PMID:15687258 PMID:15766526 PMID:17288565 PMID:20221403 PMID:22701344 PMID:27193233 MGI:5784976 MGI:5788345 MGI:5795824 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in ISO (PMID:12198173), (PMID:25014217), (PMID:25106868)
(MGI:5779430|PMID:27102483), (MGI:5784968|PMID:24700863)
(MGI:4818820|PMID:20622884), (MGI:5784967|PMID:24733888), (MGI:5784976|PMID:22701344)
(PMID:15467755), (PMID:15538381), (PMID:15687258), (PMID:18326031), (PMID:19179481), (PMID:24700863), (PMID:26542173)
UniProt PMID:12198173 PMID:15467755 PMID:15538381 PMID:15687258 PMID:18326031 PMID:19179481 PMID:20622884 PMID:22701344 PMID:24700863 PMID:24733888 PMID:25014217 PMID:25106868 PMID:26542173 PMID:27102483 MGI:4818820 MGI:5779430 MGI:5784967 MGI:5784968 MGI:5784976 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in ISO (PMID:25106868)
(MGI:4818820|PMID:20622884), (MGI:5784976|PMID:22701344)
UniProt PMID:20622884 PMID:22701344 PMID:25106868 MGI:4818820 MGI:5784976 NCBI chr2A:43,311,744...43,315,928 JBrowse link
chromatin-mediated maintenance of transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 involved_in ISO (MGI:5294291|PMID:18243098) UniProt PMID:18243098 MGI:5294291 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 involved_in ISO PMID:12917342 UniProt PMID:12917342 RGD:8553888 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G PABPC1L poly(A) binding protein cytoplasmic 1 like acts_upstream_of_or_within ISO (MGI:5688228|PMID:26134869) MGI PMID:26134869 MGI:5688228 NCBI chr20:41,240,430...41,270,036
Ensembl chr20:42,333,593...42,375,850
JBrowse link
G PADI2 peptidyl arginine deiminase 2 involved_in ISO (PMID:22853951) UniProt PMID:22853951 NCBI chr 1:16,011,708...16,064,344
Ensembl chr 1:17,067,729...17,120,513
JBrowse link
G SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 involved_in ISO (PMID:12917342) UniProt PMID:12917342 NCBI chr12:38,655,236...38,670,618
Ensembl chr12:39,552,155...39,567,804
JBrowse link
deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT7 CCR4-NOT transcription complex subunit 7 acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) MGI PMID:18625844 MGI:3807625 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G NOCT nocturnin acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) MGI PMID:18625844 MGI:3807625 NCBI chr 4:131,378,656...131,409,711
Ensembl chr 4:142,691,169...142,719,514
JBrowse link
G PAN3 poly(A) specific ribonuclease subunit PAN3 acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) MGI PMID:18625844 MGI:3807625 NCBI chr13:9,420,405...9,579,859
Ensembl chr13:27,798,607...27,921,266
JBrowse link
G PATL1 PAT1 homolog 1, processing body mRNA decay factor involved_in ISO (PMID:20584987), (PMID:20852261) UniProt PMID:20584987 PMID:20852261 NCBI chr11:54,861,349...54,893,279
Ensembl chr11:58,311,235...58,342,561
JBrowse link
exonucleolytic catabolism of deadenylated mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT6 CCR4-NOT transcription complex subunit 6 involved_in ISO (PMID:20065043) UniProt PMID:20065043 NCBI chr 5:175,695,802...175,780,534
Ensembl chr 5:183,007,081...183,089,997
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:20065043), (PMID:21336257) UniProt PMID:20065043 PMID:21336257 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G CNOT8 CCR4-NOT transcription complex subunit 8 involved_in ISO (PMID:20065043) UniProt PMID:20065043 NCBI chr 5:150,262,907...150,280,215
Ensembl chr 5:156,256,448...156,274,293
JBrowse link
G EXOSC3 exosome component 3 involved_in ISO (PMID:11782436) UniProt PMID:11782436 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G EXOSC5 exosome component 5 involved_in ISO (PMID:11782436) UniProt PMID:11782436 NCBI chr19:38,379,884...38,391,309
Ensembl chr19:46,886,326...46,897,703
JBrowse link
G EXOSC9 exosome component 9 involved_in ISO (PMID:11782436) UniProt PMID:11782436 NCBI chr 4:114,001,770...114,017,395
Ensembl chr 4:125,138,668...125,154,288
JBrowse link
mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELF1 CUGBP Elav-like family member 1 involved_in ISO PMID:30508596 ARUK-UCL PMID:30508596 RGD:38501076 NCBI chr11:47,415,600...47,515,254
Ensembl chr11:47,967,831...48,008,487
JBrowse link
G CNOT6L CCR4-NOT transcription complex subunit 6 like acts_upstream_of_or_within ISO (MGI:3828348|PMID:17452450) MGI PMID:17452450 MGI:3828348 NCBI chr 4:46,374,255...46,482,552
Ensembl chr 4:52,263,010...52,320,307
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in ISO (PMID:28002401), (PMID:30197295) UniProt PMID:28002401 PMID:30197295 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231
JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:27157137) ParkinsonsUK-UCL PMID:27157137 NCBI chr2B:119,929,004...120,090,367
Ensembl chr2B:238,847,674...239,007,549
JBrowse link
G HNRNPR heterogeneous nuclear ribonucleoprotein R ISO RGD PMID:15798208 RGD:9854643 NCBI chr 1:22,501,816...22,536,050
Ensembl chr 1:23,491,310...23,521,977
JBrowse link
G METTL14 methyltransferase 14, N6-adenosine-methyltransferase subunit involved_in ISO (MGI:5559905|PMID:24394384), (MGI:5927282|PMID:28965759) UniProt PMID:24394384 PMID:28965759 MGI:5559905 MGI:5927282 NCBI chr 4:110,879,137...110,905,131
Ensembl chr 4:121,431,026...121,458,392
JBrowse link
G METTL16 methyltransferase 16, N6-methyladenosine involved_in ISO (MGI:6114846|PMID:29262316) UniProt PMID:29262316 MGI:6114846 NCBI chr17:2,407,331...2,500,418
Ensembl chr17:2,292,498...2,376,277
JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (MGI:5559905|PMID:24394384), (MGI:5621227|PMID:25569111), (MGI:5621254|PMID:25456834), (MGI:5927282|PMID:28965759), (MGI:6094929|PMID:28792938), (MGI:6095345|PMID:28637692) UniProt PMID:24394384 PMID:25456834 PMID:25569111 PMID:28637692 PMID:28792938 PMID:28965759 MGI:5559905 MGI:5621227 MGI:5621254 MGI:5927282 MGI:6094929 MGI:6095345 NCBI chr14:2,315,868...2,329,460
Ensembl chr14:20,392,665...20,405,906
JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in ISO (MGI:5640888|PMID:25768905) UniProt PMID:25768905 MGI:5640888 NCBI chr 1:30,205,584...30,341,979
Ensembl chr 1:31,230,268...31,364,348
JBrowse link
G RBM24 RNA binding motif protein 24 involved_in ISO (PMID:29104163) UniProt PMID:29104163 NCBI chr 6:17,140,450...17,153,035 JBrowse link
G RIDA reactive intermediate imine deaminase A homolog involved_in ISO (PMID:30930054) UniProt PMID:30930054 NCBI chr 8:94,739,120...94,753,934
Ensembl chr 8:96,923,776...96,938,512
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (MGI:6271078|PMID:29353861) ARUK-UCL PMID:29353861 MGI:6271078 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) ARUK-UCL PMID:29353861 MGI:6271078 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986
JBrowse link
G YTHDF1 YTH N6-methyladenosine RNA binding protein 1 involved_in ISO (PMID:32492408)
(MGI:6490006|PMID:32943573)
UniProt PMID:32492408 PMID:32943573 MGI:6490006 NCBI chr20:59,575,703...59,596,447
Ensembl chr20:61,116,645...61,135,769
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in ISO (PMID:28106072), (PMID:32169943)
(MGI:6316439|PMID:29855337), (MGI:6316688|PMID:30065315), (MGI:6317061|PMID:30150673), (MGI:6490006|PMID:32943573), (MGI:6508516|PMID:31959747)
(PMID:27558897), (PMID:30559377), (PMID:30930054), (PMID:32492408)
UniProt PMID:27558897 PMID:28106072 PMID:29855337 PMID:30065315 PMID:30150673 PMID:30559377 PMID:30930054 PMID:31959747 PMID:32169943 PMID:32492408 PMID:32943573 MGI:6316439 MGI:6316688 MGI:6317061 MGI:6490006 MGI:6508516 NCBI chr 1:28,007,592...28,041,179
Ensembl chr 1:29,038,831...29,070,533
JBrowse link
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 involved_in ISO (PMID:32492408)
(MGI:6490006|PMID:32943573)
(PMID:28106072)
UniProt PMID:28106072 PMID:32492408 PMID:32943573 MGI:6490006 NCBI chr 8:59,701,341...59,742,865
Ensembl chr 8:61,375,832...61,413,911
JBrowse link
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL16 methyltransferase 16, N6-methyladenosine involved_in ISO (PMID:28525753) UniProt PMID:28525753 NCBI chr17:2,407,331...2,500,418
Ensembl chr17:2,292,498...2,376,277
JBrowse link
negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:32354837) UniProt PMID:32354837 NCBI chr22:12,463,859...12,515,953
Ensembl chr22:30,322,502...30,378,322
JBrowse link
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TENT4A terminal nucleotidyltransferase 4A involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chr 5:7,032,809...7,077,080
Ensembl chr 5:6,724,029...6,752,159
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chr16:30,415,668...30,494,758
Ensembl chr16:49,299,498...49,373,665
JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in ISO (PMID:18377426) UniProt PMID:18377426 NCBI chr17:44,953,343...44,957,465
Ensembl chr17:49,825,646...49,826,683
JBrowse link
nuclear polyadenylation-dependent mRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPT1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:16934922) UniProt PMID:16934922 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT6L CCR4-NOT transcription complex subunit 6 like acts_upstream_of_or_within ISO (MGI:3828348|PMID:17452450) MGI PMID:17452450 MGI:3828348 NCBI chr 4:46,374,255...46,482,552
Ensembl chr 4:52,263,010...52,320,307
JBrowse link
G PDE12 phosphodiesterase 12 involved_in ISO (PMID:21245038) UniProt PMID:21245038 NCBI chr 3:57,489,602...57,502,240
Ensembl chr 3:58,696,083...58,699,719
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5706859|PMID:26000482), (MGI:5751631|PMID:26255671) UniProt PMID:26000482 PMID:26255671 MGI:5706859 MGI:5751631 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within
ISO (PMID:23644599)
(MGI:3589099|PMID:15814898)
UniProt
MGI
PMID:15814898 PMID:23644599 MGI:3589099 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 acts_upstream_of_or_within ISO (MGI:3589099|PMID:15814898) MGI PMID:15814898 MGI:3589099 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 acts_upstream_of_or_within ISO (MGI:3589099|PMID:15814898) MGI PMID:15814898 MGI:3589099 NCBI chr2A:43,311,744...43,315,928 JBrowse link
nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT6 CCR4-NOT transcription complex subunit 6 involved_in ISO (PMID:20595389) UniProt PMID:20595389 NCBI chr 5:175,695,802...175,780,534
Ensembl chr 5:183,007,081...183,089,997
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 acts_upstream_of_or_within ISO (MGI:3807625|PMID:18625844) MGI PMID:18625844 MGI:3807625 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G MLH1 mutL homolog 1 acts_upstream_of_or_within ISO (MGI:1934053|PMID:11337385) MGI PMID:11337385 MGI:1934053 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G PARN poly(A)-specific ribonuclease acts_upstream_of_or_within ISO (MGI:3785219|PMID:18337750) MGI PMID:18337750 MGI:3785219 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PNLDC1 PARN like ribonuclease domain containing exonuclease 1 involved_in ISO (PMID:27515512)
(MGI:5825409|PMID:27515512)
UniProt PMID:27515512 MGI:5825409 NCBI chr 6:157,682,286...157,707,632
Ensembl chr 6:162,694,724...162,716,700
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within
ISO (PMID:23644599)
(MGI:3589099|PMID:15814898)
BHF-UCL
MGI
PMID:15814898 PMID:23644599 MGI:3589099 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
polyuridylation-dependent mRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TUT4 terminal uridylyl transferase 4 involved_in ISO (MGI:6162305|PMID:28792939) UniProt PMID:28792939 MGI:6162305 NCBI chr 1:51,684,408...51,815,059
Ensembl chr 1:53,292,477...53,422,893
JBrowse link
G TUT7 terminal uridylyl transferase 7 involved_in ISO (MGI:6162305|PMID:28792939) UniProt PMID:28792939 MGI:6162305 NCBI chr 9:57,433,583...57,498,675
Ensembl chr 9:85,486,521...85,554,745
JBrowse link
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:11350920) BHF-UCL PMID:11350920 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G ENDOG endonuclease G ISO RGD PMID:16407272 RGD:9685355 NCBI chr 9:99,941,856...99,945,957 JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21192280 RGD:10403035 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:15125883 RGD:10402776 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chr 7:23,415,922...23,420,767 JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G ENO1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215
JBrowse link
G IL4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22629444 RGD:7240532 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr11:73,128,457...73,140,344
Ensembl chr11:76,720,094...76,763,098
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISO (MGI:5306739|PMID:21080215) BHF-UCL PMID:21080215 MGI:5306739 NCBI chr2B:116,265,529...116,517,557 JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARGC1A PPARG coactivator 1 alpha involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chr  X:143,853,054...143,863,491
Ensembl chr  X:153,725,294...153,734,046
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:21106936) CAFA PMID:21106936 NCBI chr  X:5,587,242...5,589,417 JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:5906931|PMID:28802038) ARUK-UCL PMID:28802038 MGI:5906931 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
JBrowse link
G VCP valosin containing protein involved_in ISO (PMID:23498975) ParkinsonsUK-UCL PMID:23498975 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588
JBrowse link
positive regulation of base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM168A family with sequence similarity 168 member A involved_in ISO (PMID:25260657) UniProt PMID:25260657 NCBI chr11:68,477,579...68,674,428
Ensembl chr11:71,698,901...71,766,921
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZFP36 ZFP36 ring finger protein involved_in ISO (PMID:16364915) UniProt PMID:16364915 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:19443450) UniProt PMID:19443450 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO RGD PMID:19254952 RGD:5509898 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G C3AR1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16005543 RGD:5131269 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:20439821 RGD:7829726 NCBI chr2A:38,087,863...38,096,529
Ensembl chr2A:38,851,000...38,859,824
JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:22446327 RGD:10401140 NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569
JBrowse link
G FGF2 fibroblast growth factor 2 involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in ISO (PMID:21653700) UniProt PMID:21653700 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605
JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:16937468 RGD:9685728 NCBI chr16:716,640...720,196
Ensembl chr16:2,073,064...2,076,592
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:12721208 RGD:10045365 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G HGF hepatocyte growth factor involved_in ISO (PMID:2531289) UniProt PMID:2531289 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:9924025) UniProt PMID:9924025 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) UniProt PMID:17942966 MGI:5009390 NCBI chr11:84,330,362...84,496,755 JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 ISO RGD PMID:12890786 RGD:7775030 NCBI chr  X:100,060,647...100,345,491
Ensembl chr  X:110,672,664...110,797,992
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919) UniProt PMID:10644978 PMID:10734101 PMID:11788434 PMID:12070119 PMID:16530387 PMID:17942966 PMID:19019919 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISO (MGI:5284758|PMID:19019919) UniProt PMID:19019919 MGI:5284758 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (MGI:5306299|PMID:17226786) UniProt PMID:17226786 MGI:5306299 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:21451101 RGD:10041071 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G RGCC regulator of cell cycle involved_in ISO PMID:9756947 BHF-UCL PMID:9756947 RGD:633887 NCBI chr13:22,639,289...22,652,594
Ensembl chr13:41,228,643...41,241,909
JBrowse link
G SMOC2 SPARC related modular calcium binding 2 involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 6:166,430,178...166,664,577
Ensembl chr 6:171,366,929...171,589,084
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9395232 RGD:14696805 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in ISO (PMID:16774925) UniProt PMID:16774925 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
positive regulation of DNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO RGD PMID:27895165 RGD:12879393 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUD4 OTU deubiquitinase 4 involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr 4:137,480,809...137,527,651
Ensembl chr 4:149,135,900...149,182,476
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in ISO (MGI:5762940|PMID:23560077) UniProt PMID:23560077 MGI:5762940 NCBI chr2A:47,201,536...47,271,253
Ensembl chr2A:48,131,547...48,199,596
JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in ISO (MGI:3045816|PMID:15078895) UniProt PMID:15078895 MGI:3045816 NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr  X:33,535,543...33,683,220
Ensembl chr  X:41,232,041...41,379,910
JBrowse link
positive regulation of DNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:9600082) CACAO PMID:9600082 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403) UniProt PMID:28002403 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
positive regulation of DNA ligation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chr2A:68,509,314...68,629,192
Ensembl chr2A:69,632,459...69,744,611
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO PMID:10866811 UniProt PMID:10866811 RGD:10449519 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
G RAD51 RAD51 recombinase involved_in ISO (PMID:8929543) UniProt PMID:8929543 NCBI chr15:19,638,310...19,672,474
Ensembl chr15:37,891,056...37,925,207
JBrowse link
positive regulation of DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA3 annexin A3 ISO RGD PMID:15744063 RGD:2316072 NCBI chr 4:45,585,873...45,644,783
Ensembl chr 4:51,432,846...51,491,677
JBrowse link
G HMGB2 high mobility group box 2 ISO RGD PMID:8432381 RGD:2316096 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:19507001 RGD:2311507 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:11481036 RGD:1600909 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 ISO lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr 8:21,268,873...21,281,684
Ensembl chr 8:18,208,934...18,221,577
JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:19139380 RGD:2305938 NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479
JBrowse link
G PFN1 profilin 1 ISO RGD PMID:10966486 RGD:2324858 NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022
JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr21:30,503,194...30,520,237 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19786833) BHF-UCL PMID:19786833 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G WT1 WT1 transcription factor acts_upstream_of ISO (PMID:23042785) ARUK-UCL PMID:23042785 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
positive regulation of DNA primase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRIM2 DNA primase subunit 2 involved_in ISO (PMID:25550159) UniProt PMID:25550159 NCBI chr 6:56,875,331...56,884,118 JBrowse link
positive regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335) ARUK-UCL PMID:31453335 MGI:6358520 NCBI chr 7:92,429,776...92,457,943
Ensembl chr 7:105,832,031...105,859,995
JBrowse link
positive regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chr 4:40,711,139...40,736,763
Ensembl chr 4:46,556,892...46,581,573
JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 involved_in ISO PMID:19282473
(MGI:3698695|PMID:17121854)
UniProt PMID:17121854 PMID:19282473 MGI:3698695 RGD:8553580 NCBI chr11:6,526,477...6,550,509
Ensembl chr11:6,209,812...6,225,972
JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 involved_in ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProt PMID:19261746 PMID:19261748 PMID:19261749 NCBI chr19:16,755,518...16,767,634
Ensembl chr19:17,729,568...17,742,447
JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 involved_in ISO (PMID:19261748) UniProt PMID:19261748 NCBI chr2A:27,884,907...28,338,302
Ensembl chr2A:27,974,917...28,420,519
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17643121 PMID:19261748 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProt PMID:17525341 PMID:19261746 PMID:19261748 NCBI chr  X:144,550,320...144,592,795
Ensembl chr  X:154,389,283...154,428,669
JBrowse link
G CBX8 chromobox 8 ISO RGD PMID:23572236 RGD:9586727 NCBI chr17:73,874,618...73,877,347
Ensembl chr17:79,410,967...79,413,691
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma involved_in ISO (PMID:16255782) UniProt PMID:16255782 NCBI chr19:30,295,603...30,304,984
Ensembl chr19:39,046,219...39,046,671
JBrowse link
G DHX9 DExH-box helicase 9 involved_in ISO (PMID:24049074) UniProt PMID:24049074 NCBI chr 1:158,355,472...158,404,178
Ensembl chr 1:162,006,822...162,055,833
JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO (PMID:17115032) UniProt PMID:17115032 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:22483866) UniProt PMID:22483866 NCBI chr10:44,703,720...44,784,948 JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:7664335) UniProt PMID:7664335 NCBI chr 5:53,053,712...53,131,563
Ensembl chr 5:54,693,987...54,765,496
JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829
JBrowse link
G EYA3 EYA transcriptional coactivator and phosphatase 3 involved_in ISO (PMID:19234442) UniProt PMID:19234442 NCBI chr 1:27,230,623...27,349,355
Ensembl chr 1:28,270,116...28,386,878
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in ISO (PMID:14975937) UniProt PMID:14975937 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase ISO RGD PMID:1945835 RGD:729332 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G NPAS2 neuronal PAS domain protein 2 involved_in ISO (PMID:18819933) UniProt PMID:18819933 Ensembl chr2A:101,868,933...101,972,866 JBrowse link
G PARG poly(ADP-ribose) glycohydrolase ISO RGD PMID:15158362 RGD:2316739 NCBI chr10:44,290,391...44,420,184 JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G RNF168 ring finger protein 168 involved_in ISO (PMID:23760478)
(PMID:19203578), (PMID:19203579)
UniProt PMID:19203578 PMID:19203579 PMID:23760478 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687
JBrowse link
G RNF8 ring finger protein 8 involved_in ISO (PMID:18001824), (PMID:18001825) UniProt PMID:18001824 PMID:18001825 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:23911537) UniProt PMID:23911537 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:19934257) UniProt PMID:19934257 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:24790221) UniProt PMID:24790221 NCBI chr18:11,479,742...11,627,035
Ensembl chr18:13,785,912...13,933,887
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TMEM161A transmembrane protein 161A involved_in ISO (PMID:16551573) BHF-UCL PMID:16551573 NCBI chr19:18,557,799...18,576,722
Ensembl chr19:19,560,046...19,578,779
JBrowse link
G TRIM28 tripartite motif containing 28 involved_in ISO (PMID:17178852) UniProt PMID:17178852 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:16129784) HGNC-UCL PMID:16129784 NCBI chr12:90,951,446...90,984,075 JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:44,435,496...44,488,517
Ensembl chr 8:41,856,429...41,878,320
JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 involved_in ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProt PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 NCBI chr 5:172,205,958...172,321,758
Ensembl chr 5:179,271,577...179,374,229
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of DNA strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POT1 protection of telomeres 1 involved_in ISO (PMID:16043710) BHF-UCL PMID:16043710 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (MGI:4439421|PMID:20215406) MGI PMID:20215406 MGI:4439421 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945
JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (MGI:3513706|PMID:15585571)
(MGI:4439421|PMID:20215406)
MGI PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 9:99,282,821...99,325,404
Ensembl chr 9:127,956,915...127,982,449
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) UniProt PMID:12930902 Ensembl chr16:803,340...813,170 JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr16:49,489,176...49,503,736
Ensembl chr16:68,877,028...68,891,513
JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr 8:116,524,249...116,546,178
Ensembl chr 8:119,272,490...119,294,342
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr17:58,574,442...58,593,915
Ensembl chr17:63,667,246...63,686,503
JBrowse link
G RFC2 replication factor C subunit 2 involved_in ISO (PMID:12930902) UniProt PMID:12930902 Ensembl chr 7:81,378,937...81,401,937 JBrowse link
G RFC3 replication factor C subunit 3 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr13:15,073,464...15,220,646
Ensembl chr13:33,503,439...33,523,403
JBrowse link
G RFC4 replication factor C subunit 4 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr 3:183,824,865...183,841,895
Ensembl chr 3:192,290,639...192,307,839
JBrowse link
G RFC5 replication factor C subunit 5 involved_in ISO (PMID:12930902) UniProt PMID:12930902 NCBI chr12:115,595,398...115,611,442
Ensembl chr12:118,973,560...118,990,308
JBrowse link
positive regulation of DNA-templated transcription, elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALYREF Aly/REF export factor involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr17:76,293,410...76,297,171 JBrowse link
G DDX39B DExD-box helicase 39B involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569
JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 involved_in ISO (PMID:10882741) UniProt PMID:10882741 NCBI chr15:22,732,742...22,737,522
Ensembl chr15:40,821,759...40,827,070
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:9326587) UniProt PMID:9326587 NCBI chr10:44,703,720...44,784,948 JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in ISO (MGI:6392952|PMID:31827282) UniProt PMID:31827282 MGI:6392952 NCBI chr17:43,875,921...43,916,352
Ensembl chr17:48,605,488...48,645,784
JBrowse link
G SCAF8 SR-related CTD associated factor 8 involved_in ISO (PMID:31104839) UniProt PMID:31104839 NCBI chr 6:152,548,019...152,776,596
Ensembl chr 6:158,514,265...158,614,407
JBrowse link
G SUPT4H1 SPT4 homolog, DSIF elongation factor subunit involved_in ISO (PMID:9450929) UniProt PMID:9450929 NCBI chr17:52,420,503...52,427,514 JBrowse link
G SUPT5H SPT5 homolog, DSIF elongation factor subunit involved_in ISO (PMID:9450929) UniProt PMID:9450929 NCBI chr19:36,543,998...36,575,161
Ensembl chr19:45,092,075...45,122,335
JBrowse link
G THOC1 THO complex 1 involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr18:14,052,858...14,102,559
Ensembl chr18:17,692,797...17,742,570
JBrowse link
G THOC5 THO complex 5 involved_in ISO (PMID:22144908) UniProt PMID:22144908 NCBI chr22:10,553,665...10,599,948
Ensembl chr22:28,357,644...28,404,346
JBrowse link
positive regulation of DNA-templated transcription, initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCLAF1 BCL2 associated transcription factor 1 involved_in ISO (PMID:17938203) UniProt PMID:17938203 NCBI chr 6:134,023,195...134,054,507
Ensembl chr 6:138,115,451...138,137,108
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in ISO (PMID:28186500) UniProt PMID:28186500 NCBI chr19:30,223,567...30,226,204 JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in ISO (PMID:23027619) CACAO PMID:23027619 NCBI chr11:61,252,513...61,261,032
Ensembl chr11:64,581,841...64,589,304
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:23027619) CACAO PMID:23027619 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G MITF melanocyte inducing transcription factor involved_in ISO (PMID:12204775), (PMID:8995290) CACAO PMID:8995290 PMID:12204775 NCBI chr 3:69,674,064...69,902,078
Ensembl chr 3:71,037,665...71,265,445
JBrowse link
G SETX senataxin involved_in ISO (PMID:21700224) UniProt PMID:21700224 NCBI chr 9:103,381,356...103,474,902
Ensembl chr 9:132,016,767...132,109,665
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17332325) CACAO PMID:17332325 NCBI chr 7:19,761,041...19,765,665 JBrowse link
positive regulation of DNA-templated transcription, termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SETX senataxin involved_in ISO (PMID:19515850) UniProt PMID:19515850 NCBI chr 9:103,381,356...103,474,902
Ensembl chr 9:132,016,767...132,109,665
JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:23797032) UniProt PMID:23797032 NCBI chr12:55,176,165...55,207,123 JBrowse link
G FMN2 formin 2 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr 1:215,626,889...216,023,590 JBrowse link
G FOXM1 forkhead box M1 involved_in ISO (PMID:17101782)
(MGI:3698692|PMID:17101782)
UniProt PMID:17101782 MGI:3698692 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731) UniProt PMID:29125140 PMID:33115731 MGI:6467697 MGI:6716977 NCBI chr 6:71,089,817...71,190,700
Ensembl chr 6:74,478,303...74,479,826
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase involved_in ISO (PMID:24147153) BHF-UCL PMID:24147153 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 6:71,195,619...71,197,040
Ensembl chr 6:74,484,764...74,511,331
JBrowse link
G SLF1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) UniProt PMID:25931565 NCBI chr 5:20,660,101...20,757,072
Ensembl chr 5:20,817,614...20,884,453
JBrowse link
G SLF2 SMC5-SMC6 complex localization factor 2 involved_in ISO (PMID:25931565) UniProt PMID:25931565 NCBI chr10:97,511,398...97,566,386
Ensembl chr10:100,989,044...101,042,730
JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in ISO (PMID:23509288) UniProt PMID:23509288 NCBI chr 8:43,691,454...44,166,259
Ensembl chr 8:41,083,964...41,558,170
JBrowse link
G SPIRE1 spire type actin nucleation factor 1 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr18:1,663,614...1,881,357
Ensembl chr18:16,800,870...16,992,959
JBrowse link
G SPIRE2 spire type actin nucleation factor 2 involved_in ISO (PMID:26287480) UniProt PMID:26287480 NCBI chr16:70,580,030...70,634,143
Ensembl chr16:90,273,160...90,299,061
JBrowse link
G TIMELESS timeless circadian regulator involved_in ISO (PMID:23797032) UniProt PMID:23797032 NCBI chr12:32,465,529...32,497,581
Ensembl chr12:32,718,649...32,750,728
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:27715493) UniProt PMID:27715493 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) ARUK-UCL PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr 7:92,429,776...92,457,943
Ensembl chr 7:105,832,031...105,859,995
JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ARID2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) CACAO PMID:28381560 NCBI chr12:42,823,236...43,004,465
Ensembl chr12:43,692,914...43,871,564
JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) UniProt PMID:25820262 NCBI chr10:44,703,720...44,784,948 JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within ISO (MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:5648586 NCBI chr  X:7,470,574...7,500,958
Ensembl chr  X:14,752,934...14,781,817
JBrowse link
G FUS FUS RNA binding protein involved_in ISO (PMID:10567410) UniProt PMID:10567410 NCBI chr16:23,775,389...23,786,881
Ensembl chr16:31,551,135...31,562,327
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (PMID:31609975)
(MGI:6716962|PMID:25936915)
UniProt PMID:25936915 PMID:31609975 MGI:6716962 NCBI chr 6:71,089,817...71,190,700
Ensembl chr 6:74,478,303...74,479,826
JBrowse link
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in ISO (PMID:29225034) UniProt PMID:29225034 NCBI chr10:94,080,690...94,120,811
Ensembl chr10:97,574,257...97,614,146
JBrowse link
G MRNIP MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chr 5:174,989,967...175,020,550
Ensembl chr 5:182,299,016...182,340,632
JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) UniProt PMID:29955025 MGI:6272426 NCBI chr 6:71,195,619...71,197,040
Ensembl chr 6:74,484,764...74,511,331
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098 PMID:30356214 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) UniProt PMID:17996710 PMID:17996711 NCBI chr12:4,657,972...4,679,232
Ensembl chr12:4,578,621...4,599,879
JBrowse link
G TIMELESS timeless circadian regulator involved_in ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098 PMID:30356214 NCBI chr12:32,465,529...32,497,581
Ensembl chr12:32,718,649...32,750,728
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380
JBrowse link
G WDR48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) UniProt PMID:27239033 PMID:27463890 NCBI chr 3:38,948,440...38,992,872
Ensembl chr 3:39,228,920...39,273,300
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DTX3L deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chr 3:119,654,019...119,664,918
Ensembl chr 3:126,558,924...126,569,807
JBrowse link
G FH fumarate hydratase involved_in ISO (PMID:26237645) UniProt PMID:26237645 NCBI chr 1:217,059,847...217,081,795
Ensembl chr 1:222,041,142...222,064,212
JBrowse link
G KDM4D lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) MGI PMID:24550317 NCBI chr11:89,987,537...90,013,421 JBrowse link
G KMT5B lysine methyltransferase 5B involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr11:63,239,796...63,297,113
Ensembl chr11:66,549,230...66,581,475
JBrowse link
G KMT5C lysine methyltransferase 5C involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr19:52,381,963...52,390,507
Ensembl chr19:61,073,396...61,078,717
JBrowse link
G LOC100986203 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20620605), (PMID:21491884) UniProt PMID:20620605 PMID:21491884 NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791
JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (PMID:24598253) UniProt PMID:24598253 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in ISO (PMID:28525742) UniProt PMID:28525742 NCBI chr 3:119,617,722...119,655,039
Ensembl chr 3:126,522,859...126,559,647
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:12032095) CACAO PMID:12032095 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:26237645) UniProt PMID:26237645 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISO (PMID:28241136)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
UniProt
CACAO
PMID:23306437 PMID:23333305 PMID:28241136 MGI:5468037 MGI:5476381 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893), (PMID:29789392) UniProt PMID:29656893 PMID:29789392 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) UniProt PMID:25294876 NCBI chr18:11,479,742...11,627,035
Ensembl chr18:13,785,912...13,933,887
JBrowse link
G TOP2B DNA topoisomerase II beta ISO RGD PMID:22019940 RGD:13432143 NCBI chr 3:25,499,239...25,566,029
Ensembl chr 3:25,828,879...25,896,912
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:25512560) UniProt PMID:25512560 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:20605787) UniProt PMID:20605787 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:18499658) UniProt PMID:18499658 NCBI chr12:55,176,165...55,207,123 JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:19059439) UniProt PMID:19059439 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,476,710...31,491,411 JBrowse link
positive regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) involved_in ISO (MGI:4881347|PMID:21074248) UniProt PMID:21074248 MGI:4881347 NCBI chr14:54,522,428...54,578,501
Ensembl chr14:73,376,684...73,410,468
JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO PMID:24481529 BHF-UCL PMID:24481529 RGD:12910990 NCBI chr14:56,868,361...57,060,552
Ensembl chr14:75,839,333...76,266,895
JBrowse link
G GCK glucokinase ISO RGD PMID:17553851 RGD:2301905 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751
JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO (MGI:1927687|PMID:11147825) MGI PMID:11147825 MGI:1927687 NCBI chr12:38,644,466...38,651,924
Ensembl chr12:39,541,550...39,549,040
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A acts_upstream_of_or_within ISO (MGI:3766710|PMID:17408640) MGI PMID:17408640 MGI:3766710 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826
JBrowse link
G IFNG interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:7688386) BHF-UCL PMID:7688386 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G INS insulin involved_in ISO (PMID:7688386)
(PMID:381941)
BHF-UCL PMID:381941 PMID:7688386 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G INSR insulin receptor involved_in ISO (PMID:7693131) BHF-UCL PMID:7693131 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:11086030 RGD:1642010 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MLXIPL MLX interacting protein like involved_in ISO (PMID:19995986)
(MGI:3041761|PMID:15118080)
BHF-UCL PMID:15118080 PMID:19995986 MGI:3041761 Ensembl chr 7:80,745,765...80,776,153 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22842522 RGD:7207891 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in ISO (PMID:22898868) CACAO PMID:22898868 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO PMID:11069105 UniProt PMID:11069105 RGD:8554193 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505
JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISO PMID:11069105 UniProt PMID:11069105 RGD:8554193 NCBI chr 1:55,928,577...55,998,628
Ensembl chr 1:57,664,237...57,702,227
JBrowse link
G PRXL2C peroxiredoxin like 2C involved_in ISO (PMID:29901208) UniProt PMID:29901208 NCBI chr 9:67,737,639...67,751,691 JBrowse link
G PSEN1 presenilin 1 involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G SLC4A4 solute carrier family 4 member 4 acts_upstream_of ISO (PMID:21976511)
(MGI:5295108|PMID:21976511)
ARUK-UCL PMID:21976511 MGI:5295108 NCBI chr 4:52,659,221...52,994,053
Ensembl chr 4:59,002,200...59,385,608
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 involved_in ISO (MGI:5913553|PMID:28327662) UniProt PMID:28327662 MGI:5913553 NCBI chr 3:111,445,520...112,275,946
Ensembl chr 3:118,389,250...118,431,453
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (MGI:3794903|PMID:18340377) MGI PMID:18340377 MGI:3794903 NCBI chr17:34,849,466...34,880,088 JBrowse link
G GUCA1A guanylate cyclase activator 1A ISO RGD PMID:12545196 RGD:1599357 NCBI chr 6:41,693,593...41,774,591
Ensembl chr 6:43,045,307...43,070,520
JBrowse link
G NOS3 nitric oxide synthase 3 involved_in ISO (PMID:17502619) BHF-UCL PMID:17502619 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) MGI PMID:21255825 MGI:5009766 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chr 3:126,339,758...126,367,166
Ensembl chr 3:133,694,676...133,721,519
JBrowse link
G KMT5B lysine methyltransferase 5B involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr11:63,239,796...63,297,113
Ensembl chr11:66,549,230...66,581,475
JBrowse link
G KMT5C lysine methyltransferase 5C involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr19:52,381,963...52,390,507
Ensembl chr19:61,073,396...61,078,717
JBrowse link
G LOC100970806 exosome complex component MTR3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) MGI PMID:21255825 MGI:5009766 NCBI chr 7:140,163,275...140,176,732 JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526
JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr2B:38,721,658...38,818,488
Ensembl chr2B:155,985,960...156,052,926
JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr20:5,753,262...5,858,728
Ensembl chr20:5,537,488...5,642,107
JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr10:83,639,020...83,643,420 JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:48,376,338...48,382,052 JBrowse link
G TFRC transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
(PMID:23760478)
UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr15:22,364,696...22,472,499
Ensembl chr15:40,519,012...40,626,741
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) MGI PMID:23241889 MGI:5462481 NCBI chr 4:2,009,276...2,119,182
Ensembl chr 4:1,945,307...2,027,425
JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNFSF13 TNF superfamily member 13 acts_upstream_of_or_within ISO (MGI:3037416|PMID:14988498)
(PMID:14988498)
MGI PMID:14988498 MGI:3037416 NCBI chr17:7,589,931...7,593,527
Ensembl chr17:7,576,465...7,579,834
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCF1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chr11:62,722,611...62,734,279 JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3037416|PMID:14988498) MGI PMID:14988498 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (MGI:5763555|PMID:25404367) MGI PMID:25404367 MGI:5763555 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within ISO (MGI:62368|PMID:7688139) MGI PMID:7688139 MGI:62368 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within ISO (MGI:87443|PMID:1830926) MGI PMID:1830926 MGI:87443 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498) MGI PMID:12882831 PMID:14988498 MGI:2670820 MGI:3037416 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G LOC100976787 mismatch repair endonuclease PMS2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984
JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
JBrowse link
G MSH2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 Ensembl chr16:30,186,326...30,190,654 JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chr 7:146,546,658...146,605,912
Ensembl chr 7:158,276,798...158,330,911
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (MGI:85031|PMID:9015183) MGI PMID:9015183 MGI:85031 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G TBX21 T-box transcription factor 21 acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) MGI PMID:12882831 MGI:2670820 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660
JBrowse link
positive regulation of meiotic DNA double-strand break formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD31 ankyrin repeat domain 31 involved_in ISO (MGI:6316415|PMID:31003867), (MGI:6316551|PMID:31000436) UniProt PMID:31000436 PMID:31003867 MGI:6316415 MGI:6316551 NCBI chr 5:40,060,599...40,236,468
Ensembl chr 5:40,673,567...40,849,519
JBrowse link
positive regulation of miRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIN28B lin-28 homolog B involved_in ISO (PMID:18951094) CACAO PMID:18951094 NCBI chr 6:102,755,256...102,897,739
Ensembl chr 6:106,640,448...106,772,374
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:20547861) UniProt PMID:20547861 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (PMID:22055188), (PMID:24048733) UniProt PMID:22055188 PMID:24048733 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
G ZSWIM8 zinc finger SWIM-type containing 8 involved_in ISO (PMID:33184234), (PMID:33184237)
(MGI:6508520|PMID:33184237)
UniProt PMID:33184234 PMID:33184237 MGI:6508520 NCBI chr10:70,308,480...70,324,729
Ensembl chr10:72,981,196...72,997,070
JBrowse link
positive regulation of miRNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (MGI:4868529|PMID:20975942) MGI PMID:20975942 MGI:4868529 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940
JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) BHF-UCL PMID:23027131 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:22357537) BHF-UCL PMID:22357537 NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:22357537) BHF-UCL PMID:22357537 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
positive regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC10 histone deacetylase 10 involved_in ISO (PMID:26221039) UniProt PMID:26221039 NCBI chr22:30,473,753...30,481,369
Ensembl chr22:49,473,369...49,479,216
JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:15014079) UniProt PMID:15014079 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G PRKCG protein kinase C gamma involved_in ISO (PMID:15808853) HGNC-UCL PMID:15808853 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977
JBrowse link
positive regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARGC1A PPARG coactivator 1 alpha involved_in ISO (MGI:5463828|PMID:23150719) UniProt PMID:23150719 MGI:5463828 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
positive regulation of mitochondrial RNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRSF1 G-rich RNA sequence binding factor 1 involved_in ISO (PMID:29967381) UniProt PMID:29967381 NCBI chr 4:53,384,303...53,404,706 JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:19509288), (PMID:29967381) UniProt PMID:19509288 PMID:29967381 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
G SUPV3L1 Suv3 like RNA helicase involved_in ISO (PMID:19509288), (PMID:29967381)
(PMID:19864255)
UniProt PMID:19509288 PMID:19864255 PMID:29967381 NCBI chr10:65,647,273...65,676,179
Ensembl chr10:68,180,671...68,209,538
JBrowse link
positive regulation of mitochondrial transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (MGI:5920587|PMID:28585542) UniProt PMID:28585542 MGI:5920587 NCBI chr22:4,521,604...4,523,740 JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (MGI:6120139|PMID:23283301) UniProt PMID:23283301 MGI:6120139 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505
JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (MGI:6120139|PMID:23283301) UniProt PMID:23283301 MGI:6120139 NCBI chr11:210,052...233,969
Ensembl chr11:255,191...278,732
JBrowse link
positive regulation of mRNA 3'-end processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 ISO c-mos polyadenylation RGD PMID:15291744 RGD:1578405 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CDC73 cell division cycle 73 involved_in ISO (PMID:19136632) UniProt PMID:19136632 NCBI chr 1:168,581,730...168,710,915
Ensembl chr 1:172,875,365...173,004,934
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:27940037) UniProt PMID:27940037 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 involved_in ISO (PMID:9342333) UniProt PMID:9342333 NCBI chr 9:68,724,176...68,764,423
Ensembl chr 9:96,845,422...96,885,624
JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 involved_in ISO (PMID:9342333) UniProt PMID:9342333 NCBI chr 3:194,277,280...194,284,456
Ensembl chr 3:204,214,282...204,221,294
JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISO (PMID:21329879) UniProt PMID:21329879 NCBI chr19:36,484,099...36,489,364
Ensembl chr19:45,031,819...45,037,169
JBrowse link
positive regulation of mRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNOT1 CCR4-NOT transcription complex subunit 1 involved_in ISO (PMID:22977175) BHF-UCL PMID:22977175 NCBI chr16:38,793,212...38,902,686
Ensembl chr16:57,919,283...58,027,472
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:23386060), (PMID:25038453) UniProt PMID:23386060 PMID:25038453 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G CNOT8 CCR4-NOT transcription complex subunit 8 involved_in ISO (PMID:22977175) BHF-UCL PMID:22977175 NCBI chr 5:150,262,907...150,280,215
Ensembl chr 5:156,256,448...156,274,293
JBrowse link
G GTPBP1 GTP binding protein 1 involved_in ISO PMID:21515746 UniProt PMID:21515746 RGD:8553842 NCBI chr22:19,621,159...19,648,848
Ensembl chr22:37,438,626...37,462,933
JBrowse link
G HNRNPR heterogeneous nuclear ribonucleoprotein R ISO RGD PMID:15798208 RGD:9854643 NCBI chr 1:22,501,816...22,536,050
Ensembl chr 1:23,491,310...23,521,977
JBrowse link
G KHSRP KH-type splicing regulatory protein involved_in ISO (PMID:16126846) UniProt PMID:16126846 NCBI chr19:5,433,989...5,445,721 JBrowse link
G MOV10 Mov10 RISC complex RNA helicase involved_in ISO (PMID:24726324) UniProt PMID:24726324 NCBI chr 1:115,327,051...115,353,483
Ensembl chr 1:124,999,353...125,025,820
JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 involved_in ISO (PMID:16410805) RGD
UniProt
PMID:737213 PMID:16410805 RGD:11554176 NCBI chr2A:55,792,412...55,848,242
Ensembl chr2A:56,931,365...56,986,326
JBrowse link
G PRR5L proline rich 5 like involved_in ISO (PMID:21964062) UniProt PMID:21964062 NCBI chr11:36,269,291...36,438,954
Ensembl chr11:36,223,385...36,311,659
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5706859|PMID:26000482), (MGI:5751631|PMID:26255671)
(MGI:6154479|PMID:25026077)
UniProt PMID:25026077 PMID:26000482 PMID:26255671 MGI:5706859 MGI:5751631 MGI:6154479 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G UPF1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:25225333), (PMID:26255671)
(PMID:24726324)
UniProt PMID:24726324 PMID:25225333 PMID:26255671 NCBI chr19:18,269,878...18,306,199
Ensembl chr19:19,292,725...19,313,224
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISO (PMID:19909337)
(MGI:3842851|PMID:19322177), (MGI:5706859|PMID:26000482), (MGI:5706909|PMID:23185455), (MGI:5751631|PMID:26255671)
UniProt PMID:19322177 PMID:19909337 PMID:23185455 PMID:26000482 PMID:26255671 MGI:3842851 MGI:5706859 MGI:5706909 MGI:5751631 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO PMID:17185417
(PMID:21876179)
UniProt PMID:17185417 PMID:21876179 RGD:8553432 NCBI chr 7:131,002,580...131,068,513
Ensembl chr 7:143,489,750...143,555,438
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in ISO (MGI:5795825|PMID:15634918) UniProt PMID:15634918 MGI:5795825 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
positive regulation of mRNA cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT21 nudix hydrolase 21 involved_in ISO (PMID:15937220) UniProt PMID:15937220 NCBI chr16:36,715,373...36,737,593
Ensembl chr16:55,851,302...55,869,856
JBrowse link
positive regulation of mRNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:9792439 RGD:10041038 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203
JBrowse link
positive regulation of mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPEB1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:28383716) UniProt PMID:28383716 NCBI chr15:62,949,264...63,053,994
Ensembl chr15:80,443,096...80,526,948
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (MGI:5300629|PMID:22153079) UniProt PMID:22153079 MGI:5300629 NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089
JBrowse link
G HSF1 heat shock transcription factor 1 involved_in ISO (PMID:14707147) UniProt PMID:14707147 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G NUDT21 nudix hydrolase 21 involved_in ISO (PMID:15937220) UniProt PMID:15937220 NCBI chr16:36,715,373...36,737,593
Ensembl chr16:55,851,302...55,869,856
JBrowse link
positive regulation of mRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADARB1 adenosine deaminase RNA specific B1 ISO RGD PMID:10331393 RGD:10450893 NCBI chr21:31,374,841...31,532,721
Ensembl chr21:44,715,931...44,815,748
JBrowse link
positive regulation of mRNA splicing, via spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CELF3 CUGBP Elav-like family member 3 involved_in ISO (PMID:15009664) UniProt PMID:15009664 NCBI chr 1:127,060,330...127,075,106
Ensembl chr 1:130,701,452...130,718,578
JBrowse link
G CELF4 CUGBP Elav-like family member 4 involved_in ISO (PMID:15009664) UniProt PMID:15009664 NCBI chr18:30,495,149...30,818,358
Ensembl chr18:34,068,123...34,374,372
JBrowse link
G DAZAP1 DAZ associated protein 1 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 Ensembl chr19:1,391,764...1,408,254 JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 acts_upstream_of_or_within ISO (MGI:3814796|PMID:18480465) MGI PMID:18480465 MGI:3814796 NCBI chr17:74,221,793...74,233,738 JBrowse link
G HMX2 H6 family homeobox 2 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr10:119,700,416...119,708,444 JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773
JBrowse link
G LMNTD2 lamin tail domain containing 2 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr11:559,779...564,584
Ensembl chr11:588,816...594,794
JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 involved_in ISO (PMID:23793891) CAFA PMID:23793891 NCBI chr 9:68,724,176...68,764,423
Ensembl chr 9:96,845,422...96,885,624
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor involved_in ISO (PMID:28221134) UniProt PMID:28221134 NCBI chr11:3,553,379...3,669,367
Ensembl chr11:3,661,568...3,767,443
JBrowse link
G OBI1 ORC ubiquitin ligase 1 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr13:59,840,406...59,884,765
Ensembl chr13:78,874,466...78,918,446
JBrowse link
G PRDX6 peroxiredoxin 6 involved_in ISO (PMID:16186110) UniProt PMID:16186110 NCBI chr 1:148,988,836...149,000,345 JBrowse link
G PRPF19 pre-mRNA processing factor 19 acts_upstream_of_or_within ISO (MGI:3814796|PMID:18480465) MGI PMID:18480465 MGI:3814796 NCBI chr11:56,153,965...56,169,821
Ensembl chr11:59,595,120...59,607,828
JBrowse link
G RBMXL1 RBMX like 1 involved_in ISO PMID:19282290 UniProt PMID:19282290 RGD:2316827 NCBI chr 1:91,695,452...91,708,711 JBrowse link
G SF3B4 splicing factor 3b subunit 4 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr 1:125,268,113...125,273,405
Ensembl chr 1:128,924,317...128,929,610
JBrowse link
G SLC39A5 solute carrier family 39 member 5 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr12:32,677,330...32,685,316
Ensembl chr12:32,929,033...32,936,158
JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr19:46,094,679...46,118,022
Ensembl chr19:55,021,402...55,046,281
JBrowse link
G SNW1 SNW domain containing 1 involved_in ISO (PMID:12840015) UniProt PMID:12840015 NCBI chr14:58,271,830...58,315,773
Ensembl chr14:77,472,387...77,517,315
JBrowse link
G STH saitohin involved_in ISO (PMID:16186110) UniProt PMID:16186110 NCBI chr17:11,475,944...11,479,303 JBrowse link
G THRAP3 thyroid hormone receptor associated protein 3 involved_in ISO (PMID:20123736) UniProt PMID:20123736 NCBI chr 1:35,492,918...35,572,896
Ensembl chr 1:36,719,770...36,741,355
JBrowse link
G TRA2A transformer 2 alpha homolog acts_upstream_of_or_within ISO (MGI:5304203|PMID:22194695) MGI PMID:22194695 MGI:5304203 NCBI chr 7:24,184,844...24,213,889
Ensembl chr 7:23,791,479...23,820,124
JBrowse link
G TRA2B transformer 2 beta homolog involved_in
acts_upstream_of_or_within
ISO (PMID:15009664)
(MGI:5304203|PMID:22194695)
UniProt
MGI
PMID:15009664 PMID:22194695 MGI:5304203 NCBI chr 3:182,942,623...182,963,938
Ensembl chr 3:191,414,777...191,436,103
JBrowse link
G ZFP64 ZFP64 zinc finger protein acts_upstream_of_or_within ISO (MGI:5532638|PMID:23636947) MGI PMID:23636947 MGI:5532638 NCBI chr20:48,430,392...48,535,618
Ensembl chr20:49,516,786...49,653,435
JBrowse link
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125
JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 involved_in ISO (PMID:21278420) UniProt PMID:21278420 NCBI chr16:38,793,212...38,902,686
Ensembl chr16:57,919,283...58,027,472
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:21278420)
(MGI:5486537|PMID:19716330)
UniProt PMID:19716330 PMID:21278420 MGI:5486537 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:14731398) UniProt PMID:14731398 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 involved_in ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr10:115,603,040...115,607,245 JBrowse link
G NANOS2 nanos C2HC-type zinc finger 2 involved_in ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr19:42,922,655...42,924,679
Ensembl chr19:51,459,529...51,459,945
JBrowse link
G NANOS3 nanos C2HC-type zinc finger 3 involved_in ISO (PMID:24736845) BHF-UCL PMID:24736845 NCBI chr19:13,427,661...13,443,218
Ensembl chr19:14,170,699...14,173,013
JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chr 8:97,346,433...97,365,628
Ensembl chr 8:99,518,347...99,537,614
JBrowse link
G TNRC6B trinucleotide repeat containing adaptor 6B involved_in ISO (PMID:19716330) UniProt PMID:19716330 NCBI chr22:21,149,646...21,240,006
Ensembl chr22:38,850,107...39,045,914
JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C involved_in ISO (PMID:21984185) UniProt PMID:21984185 NCBI chr17:72,035,737...72,185,489
Ensembl chr17:77,633,564...77,738,511
JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chr17:44,953,343...44,957,465
Ensembl chr17:49,825,646...49,826,683
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in ISO (PMID:12748283)
(MGI:5487524|PMID:21278420)
UniProt PMID:12748283 PMID:21278420 MGI:5487524 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in ISO PMID:12748283 UniProt PMID:12748283 RGD:11344945 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in ISO (MGI:5320815|PMID:22367205) UniProt PMID:22367205 MGI:5320815 NCBI chr2A:43,311,744...43,315,928 JBrowse link
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chr 8:137,192,037...137,308,059
Ensembl chr 8:140,287,647...140,361,125
JBrowse link
G BTG2 BTG anti-proliferation factor 2 acts_upstream_of_or_within ISO (PMID:18337750) MGI PMID:18337750 NCBI chr 1:178,907,317...178,911,410
Ensembl chr 1:183,201,297...183,205,404
JBrowse link
G CNOT1 CCR4-NOT transcription complex subunit 1 involved_in ISO (PMID:21278420)
(PMID:23644599)
UniProt
BHF-UCL
PMID:21278420 PMID:23644599 NCBI chr16:38,793,212...38,902,686
Ensembl chr16:57,919,283...58,027,472
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:21278420)
(MGI:5486537|PMID:19716330)
UniProt PMID:19716330 PMID:21278420 MGI:5486537 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chr10:88,794,186...89,038,808
Ensembl chr10:92,320,240...92,506,089
JBrowse link
G EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:32354837) UniProt PMID:32354837 NCBI chr22:12,463,859...12,515,953
Ensembl chr22:30,322,502...30,378,322
JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 involved_in ISO (MGI:5486537|PMID:19716330) UniProt PMID:19716330 MGI:5486537 NCBI chr 8:97,346,433...97,365,628
Ensembl chr 8:99,518,347...99,537,614
JBrowse link
G TNRC6B trinucleotide repeat containing adaptor 6B involved_in ISO (PMID:19716330) UniProt PMID:19716330 NCBI chr22:21,149,646...21,240,006
Ensembl chr22:38,850,107...39,045,914
JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C involved_in ISO (PMID:21984185) UniProt PMID:21984185 NCBI chr17:72,035,737...72,185,489
Ensembl chr17:77,633,564...77,738,511
JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chr17:44,953,343...44,957,465
Ensembl chr17:49,825,646...49,826,683
JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in ISO (PMID:10330172)
(MGI:5487524|PMID:21278420)
(MGI:5795819|PMID:20595389)
UniProt PMID:10330172 PMID:20595389 PMID:21278420 MGI:5487524 MGI:5795819 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390
JBrowse link
positive regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB2 high mobility group box 2 involved_in ISO (PMID:978439) UniProt PMID:978439 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
positive regulation of nucleic acid-templated transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in ISO (PMID:14609956), (PMID:16777850) UniProt PMID:14609956 PMID:16777850 NCBI chr10:75,581,794...75,829,748
Ensembl chr10:78,294,867...78,492,475
JBrowse link
positive regulation of pri-miRNA transcription by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLN apelin involved_in ISO (PMID:23263626) BHF-UCL PMID:23263626 NCBI chr  X:118,775,509...118,785,224 JBrowse link
G ATOH8 atonal bHLH transcription factor 8 involved_in ISO (PMID:27780851) BHF-UCL PMID:27780851 NCBI chr2A:85,803,414...85,837,858
Ensembl chr2A:87,352,904...87,362,938
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in ISO (MGI:4939577|PMID:21145505) BHF-UCL PMID:21145505 MGI:4939577 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in ISO (MGI:4939577|PMID:21145505) BHF-UCL PMID:21145505 MGI:4939577 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in ISO (MGI:4939577|PMID:21145505) BHF-UCL PMID:21145505 MGI:4939577 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
G CTCF CCCTC-binding factor involved_in ISO PMID:27124358 BHF-UCL PMID:27124358 RGD:11344932 NCBI chr16:47,906,503...47,983,271
Ensembl chr16:67,302,952...67,372,041
JBrowse link
G EGR1 early growth response 1 involved_in ISO (PMID:19307576) ARUK-UCL PMID:19307576 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor involved_in ISO (PMID:21711453) BHF-UCL PMID:21711453 NCBI chr11:123,272,111...123,400,413
Ensembl chr11:127,174,721...127,288,673
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in ISO PMID:18384814 BHF-UCL PMID:18384814 RGD:10402042 NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr11:61,252,513...61,261,032
Ensembl chr11:64,581,841...64,589,304
JBrowse link
G FOXO3 forkhead box O3 involved_in ISO (MGI:4881905|PMID:19933931) BHF-UCL PMID:19933931 MGI:4881905 NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272
JBrowse link
G GATA2 GATA binding protein 2 involved_in ISO (PMID:27780851) BHF-UCL PMID:27780851 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035
JBrowse link
G GATA3 GATA binding protein 3 involved_in ISO (PMID:26451614) BHF-UCL PMID:26451614 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G GNL3 G protein nucleolar 3 involved_in ISO (PMID:25569094) BHF-UCL PMID:25569094 NCBI chr 3:52,626,424...52,635,009
Ensembl chr 3:53,854,257...53,862,818
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in ISO (PMID:19782034)
(PMID:19141645), (PMID:24983504), (PMID:33108349)
ARUK-UCL
BHF-UCL
PMID:19141645 PMID:19782034 PMID:24983504 PMID:33108349 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G IL10 interleukin 10 involved_in ISO (PMID:23071313) ARUK-UCL PMID:23071313 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:19962668), (PMID:24375836)
PMID:18384814
BHF-UCL PMID:18384814 PMID:19962668 PMID:24375836 RGD:10402042 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KLF4 Kruppel like factor 4 involved_in ISO (PMID:23867820) BHF-UCL PMID:23867820 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797
JBrowse link
G KLF5 Kruppel like factor 5 involved_in ISO (PMID:28408180) BHF-UCL PMID:28408180 NCBI chr13:54,287,578...54,310,216 JBrowse link
G MRTFA myocardin related transcription factor A involved_in ISO (PMID:23764775) ARUK-UCL PMID:23764775 NCBI chr22:21,314,829...21,536,673
Ensembl chr22:39,413,002...39,467,402
JBrowse link
G MRTFB myocardin related transcription factor B involved_in ISO (PMID:23764775) ARUK-UCL PMID:23764775 NCBI chr16:12,999,165...13,195,012
Ensembl chr16:14,493,351...14,613,860
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO PMID:24676391 BHF-UCL PMID:24676391 RGD:10400879 NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098
JBrowse link
G NGFR nerve growth factor receptor involved_in ISO (PMID:26268439) BHF-UCL PMID:26268439 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 involved_in ISO (PMID:27334923)
(MGI:5616008|PMID:25510864)
ARUK-UCL
BHF-UCL
PMID:25510864 PMID:27334923 MGI:5616008 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISO (PMID:19088079) BHF-UCL PMID:19088079 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28566713) BHF-UCL PMID:28566713 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PRL prolactin involved_in ISO (PMID:23619365) BHF-UCL PMID:23619365 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:23619365), (PMID:26268439)
PMID:28484848
PMID:20546595
BHF-UCL PMID:20546595 PMID:23619365 PMID:26268439 PMID:28484848 RGD:12903243 RGD:13601996 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G SMAD1 SMAD family member 1 involved_in ISO (MGI:4939577|PMID:21145505) BHF-UCL PMID:21145505 MGI:4939577 NCBI chr 4:137,822,269...137,899,700
Ensembl chr 4:149,481,836...149,558,135
JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO (PMID:26311719) BHF-UCL PMID:26311719 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SMAD4 SMAD family member 4 involved_in ISO (MGI:6094665|PMID:23426367) BHF-UCL PMID:23426367 MGI:6094665 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359
JBrowse link
G SMAD6 SMAD family member 6 involved_in ISO (MGI:4939577|PMID:21145505) BHF-UCL PMID:21145505 MGI:4939577 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in ISO (PMID:25569094) BHF-UCL PMID:25569094 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (PMID:20972335)
(MGI:5693226|PMID:18384814)
BHF-UCL PMID:18384814 PMID:20972335 MGI:5693226 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:24296663)
(MGI:5501359|PMID:23823476)
BHF-UCL PMID:23823476 PMID:24296663 MGI:5501359 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (MGI:5501359|PMID:23823476) BHF-UCL PMID:23823476 MGI:5501359 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947
JBrowse link
G SRF serum response factor involved_in ISO (MGI:4354665|PMID:19578358), (MGI:5688838|PMID:21303526)
(PMID:23764775)
BHF-UCL
ARUK-UCL
PMID:19578358 PMID:21303526 PMID:23764775 MGI:4354665 MGI:5688838 NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in ISO (PMID:19390056), (PMID:23820254)
(MGI:5897552|PMID:20546595)
BHF-UCL PMID:19390056 PMID:20546595 PMID:23820254 MGI:5897552 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TEAD1 TEA domain transcription factor 1 involved_in ISO (PMID:26045994) BHF-UCL PMID:26045994 NCBI chr11:12,841,564...13,111,506
Ensembl chr11:12,624,281...12,796,541
JBrowse link
G TERT telomerase reverse transcriptase involved_in ISO (PMID:25569094) BHF-UCL PMID:25569094 NCBI chr 5:1,542,217...1,586,775
Ensembl chr 5:1,300,960...1,338,872
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:26311719), (PMID:26493107) BHF-UCL PMID:26311719 PMID:26493107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:25217442) BHF-UCL PMID:25217442 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in ISO PMID:21704009 BHF-UCL PMID:21704009 RGD:12792988 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G TNF tumor necrosis factor acts_upstream_of ISO (PMID:22499991) BHF-UCL PMID:22499991 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TP53 tumor protein p53 involved_in ISO (PMID:20546595)
(PMID:22499991)
BHF-UCL PMID:20546595 PMID:22499991 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G WT1 WT1 transcription factor involved_in ISO (PMID:23042785) ARUK-UCL PMID:23042785 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G DDX5 DEAD-box helicase 5 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142
JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:27252421) ARUK-UCL PMID:27252421 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LIN28A lin-28 homolog A involved_in ISO (MGI:5294254|PMID:21962509) BHF-UCL PMID:21962509 MGI:5294254 NCBI chr 1:25,674,751...25,693,684
Ensembl chr 1:26,739,268...26,758,028
JBrowse link
G LOC100977025 dual specificity mitogen-activated protein kinase kinase 2 involved_in ISO (PMID:24375836) BHF-UCL PMID:24375836 NCBI chr19:3,114,445...3,148,619
Ensembl chr19:4,064,626...4,097,933
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO (PMID:24375836) BHF-UCL PMID:24375836 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161
JBrowse link
G MYOCD myocardin involved_in ISO (MGI:6414695|PMID:28342807) ARUK-UCL PMID:28342807 MGI:6414695 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659
JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 acts_upstream_of_or_within ISO (MGI:5574156|PMID:24349493) MGI PMID:24349493 MGI:5574156 NCBI chr 5:21,773,283...21,785,746
Ensembl chr 5:21,910,463...21,918,776
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:26020802) ARUK-UCL PMID:26020802 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TP53 tumor protein p53 involved_in ISO (PMID:26100857)
(PMID:22578566)
BHF-UCL
ARUK-UCL
PMID:22578566 PMID:26100857 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRDM9 PR/SET domain 9 acts_upstream_of_or_within ISO (MGI:4452589|PMID:20044538), (MGI:5306625|PMID:22028627)
(PMID:21750151)
MGI PMID:20044538 PMID:21750151 PMID:22028627 MGI:4452589 MGI:5306625 NCBI chr 5:86,847,131...86,856,802
Ensembl chr 5:92,377,523...92,395,486
JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in ISO (PMID:17996711) UniProt PMID:17996711 NCBI chr12:4,657,972...4,679,232
Ensembl chr12:4,578,621...4,599,879
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B acts_upstream_of_or_within ISO (MGI:2450033|PMID:12556476) MGI PMID:12556476 MGI:2450033 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
positive regulation of RNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1B interleukin 1 beta involved_in ISO (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G NMD3 NMD3 ribosome export adaptor involved_in ISO (PMID:23782956) ParkinsonsUK-UCL PMID:23782956 NCBI chr 3:158,235,646...158,267,316
Ensembl chr 3:166,282,258...166,313,798
JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor acts_upstream_of_or_within ISO (MGI:62922|PMID:8215422) MGI PMID:8215422 MGI:62922 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G CAND1 cullin associated and neddylation dissociated 1 involved_in ISO PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr12:21,592,833...21,638,382
Ensembl chr12:22,099,962...22,145,013
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130
JBrowse link
G ESR1 estrogen receptor 1 involved_in ISO (PMID:9841876) CAFA PMID:9841876 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:5317044|PMID:21245044) MGI PMID:21245044 MGI:5317044 NCBI chr 7:50,946,817...51,047,168
Ensembl chr 7:51,191,685...51,291,245
JBrowse link
G TP53 tumor protein p53 involved_in ISO (PMID:24289924) BHF-UCL PMID:24289924 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) MGI PMID:19056892 MGI:3820325 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734
JBrowse link
positive regulation of RNA splicing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO (PMID:28377597) ARUK-UCL PMID:28377597 RGD:13464257 NCBI chr21:23,729,204...23,878,820
Ensembl chr21:37,137,253...37,231,987
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:11779464), (PMID:19622636)
(MGI:6114871|PMID:25164867)
UniProt PMID:11779464 PMID:19622636 PMID:25164867 MGI:6114871 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G HABP4 hyaluronan binding protein 4 involved_in ISO (PMID:19523114) UniProt PMID:19523114 NCBI chr 9:67,545,866...67,587,270
Ensembl chr 9:95,668,184...95,707,653
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:22684629 RGD:10002775 NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756
JBrowse link
G HNRNPLL heterogeneous nuclear ribonucleoprotein L like involved_in ISO (PMID:18669861) UniProt PMID:18669861 NCBI chr2A:38,585,301...38,629,509
Ensembl chr2A:39,345,857...39,389,842
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 ISO RGD PMID:11118435 RGD:632715 NCBI chr 8:132,131,953...132,331,310
Ensembl chr 8:135,084,505...135,282,766
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:20348923) UniProt PMID:20348923 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G POLR2A RNA polymerase II subunit A involved_in ISO (PMID:21536736) UniProt PMID:21536736 NCBI chr17:7,516,940...7,546,989
Ensembl chr17:7,502,807...7,532,521
JBrowse link
G RBM20 RNA binding motif protein 20 involved_in ISO PMID:22466703
(MGI:5442495|PMID:22466703)
(PMID:22466703)
UniProt PMID:22466703 MGI:5442495 RGD:7241566 NCBI chr10:107,240,854...107,433,749
Ensembl chr10:110,822,255...110,882,909
JBrowse link
G RBM22 RNA binding motif protein 22 involved_in ISO (PMID:22246180) UniProt PMID:22246180 NCBI chr 5:146,115,077...146,125,383
Ensembl chr 5:152,118,945...152,129,261
JBrowse link
G SETX senataxin involved_in ISO (PMID:19515850) UniProt PMID:19515850 NCBI chr 9:103,381,356...103,474,902
Ensembl chr 9:132,016,767...132,109,665
JBrowse link
G SLC38A2 solute carrier family 38 member 2 involved_in ISO (PMID:22215663) ARUK-UCL PMID:22215663 NCBI chr12:42,359,637...42,374,251
Ensembl chr12:43,230,007...43,244,343
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO RGD PMID:16308321 RGD:11038784 NCBI chr17:52,083,676...52,087,454
Ensembl chr17:56,937,295...56,944,425
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:9199345 RGD:11039429 NCBI chr14:50,320,820...50,365,650
Ensembl chr14:69,230,730...69,236,596
JBrowse link
G U2AF2 U2 small nuclear RNA auxiliary factor 2 involved_in ISO (PMID:21536736) UniProt PMID:21536736 NCBI chr19:52,701,314...52,721,612
Ensembl chr19:61,387,109...61,405,943
JBrowse link
G ZPR1 ZPR1 zinc finger involved_in ISO (PMID:11283611) UniProt PMID:11283611 NCBI chr11:111,613,940...111,623,539
Ensembl chr11:115,547,973...115,557,883
JBrowse link
positive regulation of rRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor involved_in ISO (PMID:25851604) UniProt PMID:25851604 Ensembl chr 7:80,836,518...80,851,497 JBrowse link
G DIMT1 DIM1 rRNA methyltransferase and ribosome maturation factor involved_in ISO (PMID:25851604) UniProt PMID:25851604 NCBI chr 5:51,593,030...51,608,687
Ensembl chr 5:53,234,921...53,250,079
JBrowse link
G HEATR1 HEAT repeat containing 1 involved_in ISO (PMID:17699751) UniProt PMID:17699751 NCBI chr 1:212,110,229...212,164,299
Ensembl chr 1:217,109,359...217,164,791
JBrowse link
G RIOK1 RIO kinase 1 involved_in ISO (PMID:22072790) UniProt PMID:22072790 NCBI chr 6:7,229,161...7,257,414
Ensembl chr 6:7,496,983...7,523,623
JBrowse link
G RIOK2 RIO kinase 2 involved_in ISO (PMID:19564402) UniProt PMID:19564402 NCBI chr 5:92,473,239...92,494,763
Ensembl chr 5:98,028,426...98,048,256
JBrowse link
G SIRT7 sirtuin 7 involved_in ISO (PMID:26867678) UniProt PMID:26867678 NCBI chr17:76,317,560...76,323,761
Ensembl chr17:82,020,077...82,026,289
JBrowse link
G TRMT112 tRNA methyltransferase activator subunit 11-2 involved_in ISO (PMID:25851604) UniProt PMID:25851604 NCBI chr11:59,673,737...59,675,005
Ensembl chr11:63,018,695...63,020,086
JBrowse link
G UTP15 UTP15 small subunit processome component involved_in ISO (PMID:17699751) UniProt PMID:17699751 NCBI chr 5:41,735,713...41,753,026
Ensembl chr 5:42,337,245...42,349,974
JBrowse link
G WDR43 WD repeat domain 43 involved_in ISO (PMID:17699751) UniProt PMID:17699751 NCBI chr2A:28,901,521...28,955,579
Ensembl chr2A:28,987,883...29,033,049
JBrowse link
G WDR75 WD repeat domain 75 involved_in ISO (PMID:17699751) UniProt PMID:17699751 NCBI chr2B:76,748,487...76,782,649
Ensembl chr2B:194,668,211...194,702,343
JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:28002403)
(MGI:5902647|PMID:28002403)
UniProt PMID:28002403 MGI:5902647 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403)
(MGI:5902647|PMID:28002403)
UniProt PMID:28002403 MGI:5902647 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
positive regulation of snRNA transcription by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARP7 La ribonucleoprotein 7, transcriptional regulator involved_in ISO (PMID:28254838) UniProt PMID:28254838 NCBI chr 4:105,128,335...105,149,498
Ensembl chr 4:115,698,093...115,711,003
JBrowse link
G MEPCE methylphosphate capping enzyme involved_in ISO (PMID:28254838) UniProt PMID:28254838 NCBI chr 7:92,457,967...92,463,102
Ensembl chr 7:105,861,205...105,864,739
JBrowse link
G MYOD1 myogenic differentiation 1 involved_in ISO (MGI:6148658|PMID:25217815) UniProt PMID:25217815 MGI:6148658 NCBI chr11:17,772,317...17,774,884
Ensembl chr11:17,456,124...17,458,690
JBrowse link
G ZNF143 zinc finger protein 143 involved_in ISO (PMID:9009278) GO_Central PMID:9009278 NCBI chr11:9,597,377...9,661,744
Ensembl chr11:9,331,199...9,392,754
JBrowse link
positive regulation of strand invasion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRN WRN RecQ like helicase involved_in ISO (PMID:26420422) BHF-UCL PMID:26420422 NCBI chr 8:30,353,643...30,492,978
Ensembl chr 8:27,541,145...27,679,855
JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
G SLX4 SLX4 structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200 NCBI chr16:2,502,334...2,532,172
Ensembl chr16:3,678,018...3,707,842
JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25467444)
(MGI:3047190|PMID:15240872)
BHF-UCL
MGI
PMID:15240872 PMID:25467444 MGI:3047190 NCBI chr  X:144,243,493...144,257,419
Ensembl chr  X:154,084,412...154,098,475
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16545136) BHF-UCL PMID:16545136 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in ISO (PMID:19015635), (PMID:20938050) UniProt PMID:19015635 PMID:20938050 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G KLF4 Kruppel like factor 4 involved_in ISO (PMID:20629177) BHF-UCL PMID:20629177 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5810267|PMID:9637678) BHF-UCL PMID:9637678 MGI:5810267 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO (PMID:27510903) BHF-UCL PMID:27510903 NCBI chr 4:155,383,245...155,425,479
Ensembl chr 4:167,157,770...167,214,065
JBrowse link
G NEK2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G NVL nuclear VCP like involved_in ISO (PMID:22226966) UniProt PMID:22226966 NCBI chr 1:199,695,388...199,798,080
Ensembl chr 1:204,704,371...204,806,959
JBrowse link
G PARM1 prostate androgen-regulated mucin-like protein 1 involved_in ISO PMID:12772192 UniProt PMID:12772192 RGD:8553456 NCBI chr 4:49,153,654...49,270,384
Ensembl chr 4:54,987,767...55,104,461
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in ISO (PMID:26482878) BHF-UCL PMID:26482878 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G POT1 protection of telomeres 1 involved_in ISO (PMID:16043710), (PMID:17237768)
(PMID:15181449)
BHF-UCL PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PRKCQ protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G PTGES3 prostaglandin E synthase 3 involved_in ISO (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)
(PMID:19740745)
BHF-UCL PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr12:32,221,908...32,247,228
Ensembl chr12:32,476,835...32,503,181
JBrowse link
G TCP1 t-complex 1 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985
JBrowse link
G TNKS tankyrase involved_in ISO (PMID:12782650) BHF-UCL PMID:12782650 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:23685356), (PMID:25467444)
(MGI:6189679|PMID:29804836)
(PMID:19179534), (PMID:23685356), (PMID:29804836)
BHF-UCL
UniProt
PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 MGI:6189679 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) BHF-UCL PMID:22633954 MGI:5438900 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G NABP2 nucleic acid binding protein 2 involved_in ISO (PMID:25589350)
(MGI:5629774|PMID:25589350)
BHF-UCL PMID:25589350 MGI:5629774 NCBI chr12:32,685,521...32,693,318
Ensembl chr12:32,937,017...32,944,754
JBrowse link
G NEK2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G PRKCQ protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) BHF-UCL PMID:23959892
G TNKS tankyrase involved_in ISO (PMID:25939383)
(PMID:21531765)
BHF-UCL PMID:21531765 PMID:25939383 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G TNKS2 tankyrase 2 involved_in ISO (PMID:21531765)
(PMID:25939383)
BHF-UCL PMID:21531765 PMID:25939383 NCBI chr10:88,547,396...88,612,973
Ensembl chr10:92,070,362...92,134,911
JBrowse link
positive regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:4454526|PMID:20110566) UniProt PMID:20110566 MGI:4454526 NCBI chr  X:66,682,968...66,969,421
Ensembl chr  X:76,795,574...77,083,486
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:22238380) UniProt PMID:22238380 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G GNL3 G protein nucleolar 3 involved_in ISO (PMID:22641345) BHF-UCL PMID:22641345 NCBI chr 3:52,626,424...52,635,009
Ensembl chr 3:53,854,257...53,862,818
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966
JBrowse link
G NBN nibrin involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:22641345), (PMID:26119943) BHF-UCL PMID:22641345 PMID:26119943 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 involved_in ISO (PMID:23426265) BHF-UCL PMID:23426265 NCBI chr 6:30,342,669...30,359,644
Ensembl chr 6:31,212,522...31,229,697
JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in ISO (PMID:16374507) BHF-UCL PMID:16374507 NCBI chr 5:127,972,630...128,059,911 JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) BHF-UCL PMID:22579284 MGI:5645200
G SIRT6 sirtuin 6 involved_in ISO (PMID:23201774), (PMID:25819580) BHF-UCL PMID:23201774 PMID:25819580 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126
JBrowse link
G TERF2 telomeric repeat binding factor 2 acts_upstream_of_or_within ISO (MGI:3615734|PMID:15968270) MGI PMID:15968270 MGI:3615734 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr 3:139,482,606...139,612,274
Ensembl chr 3:147,075,185...147,196,261
JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 1:131,652,058...131,679,802
Ensembl chr 1:135,481,427...135,508,983
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 5:10,565,911...10,580,808
Ensembl chr 5:10,424,157...10,440,613
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:56,664,757...56,677,000
Ensembl chr 7:57,087,072...57,098,613
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:73,287,026...73,305,792
Ensembl chr2A:74,775,781...74,794,515
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr21:15,489,698...15,507,292
Ensembl chr21:28,878,113...28,895,912
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link