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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of muscle contraction
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Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction


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positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:3,115,357...3,130,289 JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chrNW_004936471:26,589,251...26,628,302 JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:4,964,526...5,011,808 JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chrNW_004936757:149,366...237,710 JBrowse link
G Ccn2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chrNW_004936560:42,561...45,748 JBrowse link
G Chga chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chrNW_004936733:915,700...927,220 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chrNW_004936835:316,767...321,999 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:707,122...994,206 JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Rgs2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936638:1,065,866...1,068,649 JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO (MGI:4437553|PMID:18678771) MGI PMID:18678771 MGI:4437553 NCBI chrNW_004936755:264,635...285,668 JBrowse link
G Ucn urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chrNW_004936493:5,258,574...5,260,692 JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17322067 RGD:12910822 NCBI chrNW_004936482:17,162,854...17,238,319 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:24170253 RGD:10043193 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,033,854...3,046,364 JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,818,301...11,836,221 JBrowse link
G Mylk2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chrNW_004936485:18,782,890...18,795,942 JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 RGD:12907565 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Ptafr platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chrNW_004936474:12,333,905...12,337,140 JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chrNW_004936698:650,225...746,593 JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:9832052 RGD:12910753 NCBI chrNW_004936482:17,162,854...17,238,319 JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chrNW_004936593:268,736...273,623 JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chrNW_004936482:17,162,854...17,238,319 JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (MGI:3794903|PMID:18340377) MGI PMID:18340377 MGI:3794903 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in ISO
IEA
RGD
Ensembl
PMID:19041301 GO_REF:0000107 RGD:5688345 NCBI chrNW_004936757:149,366...237,710 JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2672939|PMID:12925702) MGI
InterPro
Ensembl
PMID:12925702 GO_REF:0000002 GO_REF:0000107 MGI:2672939 NCBI chrNW_004936484:13,953,141...14,373,174 JBrowse link
G Cttn cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:481,234...503,857 JBrowse link
G Edn1 endothelin 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:66444|PMID:8010105) RGD
Ensembl
MGI
PMID:8010105 PMID:8893723 PMID:12396026 GO_REF:0000107 MGI:66444 RGD:1581797 RGD:8662282 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Edn2 endothelin 2 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:65983|PMID:2768235) RGD
Ensembl
MGI
PMID:2768235 PMID:12396026 GO_REF:0000107 MGI:65983 RGD:1581797 NCBI chrNW_004936474:23,061,219...23,064,525 JBrowse link
G F2r coagulation factor II thrombin receptor ISO RGD PMID:14699501 RGD:1582292 NCBI chrNW_004936549:226,508...247,024 JBrowse link
G Itga2 integrin subunit alpha 2 ISO SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chrNW_004936480:14,320,292...14,417,828 JBrowse link
G Myocd myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nmu neuromedin U involved_in ISO PMID:3178840 RGD
UniProt
PMID:3178840 PMID:16474416 RGD:13461757 RGD:1642122
G Npnt nephronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936814:1,096,604...1,165,755 JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chrNW_004936576:1,932,526...1,939,560 JBrowse link
G Prok2 prokineticin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936603:3,299,736...3,419,539 JBrowse link
G Ptafr platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chrNW_004936474:12,333,905...12,337,140 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 RGD:2300247 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:17379756 RGD:1642962 NCBI chrNW_004936529:1,000,050...1,045,655 JBrowse link
G Sphk1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:1,482,830...1,489,337 JBrowse link
G Srf serum response factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:16,779,941...16,789,499 JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2672939|PMID:12925702) MGI
Ensembl
PMID:12925702 GO_REF:0000107 MGI:2672939 NCBI chrNW_004936588:2,040,712...2,044,635 JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:18562635 RGD:10043314 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in ISO PMID:2055247 UniProt PMID:2055247 RGD:13461751
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3688972|PMID:11507009) MGI
Ensembl
PMID:11507009 GO_REF:0000107 MGI:3688972 NCBI chrNW_004936627:1,555,151...1,584,370 JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 ISO RGD PMID:32706268 RGD:38549369 NCBI chrNW_004936769:1,424,526...1,447,547 JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chrNW_004936530:7,543,743...7,621,392 JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:17664026 PMID:19634638 RGD:2313546 RGD:6893570 NCBI chrNW_004936744:249,673...253,040 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:19208792 RGD:2316554 NCBI chrNW_004936474:15,293,115...15,314,072 JBrowse link
G Oxtr oxytocin receptor ISO RGD PMID:19164477 RGD:2303954 NCBI chrNW_004936602:4,241,743...4,259,866 JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:12390879 RGD:2305937 NCBI chrNW_004936556:1,266,621...1,421,271 JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:12390879 RGD:2305937 NCBI chrNW_004936521:9,053,179...9,065,790 JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor muscarinic 3 ISO RGD PMID:8428203 RGD:2303387 NCBI chrNW_004936484:13,953,141...14,373,174 JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5638847|PMID:24335996) MGI
Ensembl
PMID:24335996 GO_REF:0000107 MGI:5638847 NCBI chrNW_004936529:1,000,050...1,045,655 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14993
    positive regulation of biological process 5847
      positive regulation of multicellular organismal process 1563
        positive regulation of muscle contraction 48
          positive regulation of smooth muscle contraction + 32
          positive regulation of striated muscle contraction + 15
Path 2
Term Annotations click to browse term
  biological_process 14993
    biological regulation 10745
      regulation of biological process 10186
        regulation of multicellular organismal process 2777
          regulation of system process 642
            regulation of muscle system process 259
              regulation of muscle contraction 163
                positive regulation of muscle contraction 48
                  positive regulation of smooth muscle contraction + 32
                  positive regulation of striated muscle contraction + 15
paths to the root