Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of muscle contraction
go back to main search page
Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction


show annotations for term's descendants           Sort by:
positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:11,798,839...11,839,591
Ensembl chr  X:11,798,839...11,900,594 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr25:30,690,959...30,801,484
Ensembl chr25:30,693,571...30,801,486 		JBrowse link
G CCN2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145 		JBrowse link
G CHGA chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr 8:1,970,966...1,973,511 JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
G NPPA natriuretic peptide A involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494 		JBrowse link
G SMTN smoothelin acts_upstream_of_or_within ISO (PMID:18678771) MGI PMID:18678771 NCBI chr26:24,085,356...24,108,005
Ensembl chr26:24,085,382...24,108,540 		JBrowse link
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312 		JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17322067 RGD:12910822 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:24170253 RGD:10043193 NCBI chr 6:74,932,789...74,986,573 JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,384,981...18,400,038
Ensembl chr 6:18,385,007...18,400,036 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr24:21,284,309...21,297,889
Ensembl chr24:21,284,352...21,309,363 		JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 RGD:12907565 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352 		JBrowse link
G SPX spexin hormone involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:25,561,636...25,572,310
Ensembl chr27:25,563,606...25,571,093 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19258489 RGD:2304084 NCBI chr24:18,193,381...18,194,232
Ensembl chr24:18,193,339...18,194,170 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chr15:22,114,014...22,159,287 JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:9832052 RGD:12910753 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18340377) Ensembl
MGI		 PMID:18340377 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO
IEA		 RGD
Ensembl		 PMID:19041301 GO_REF:0000107 RGD:5688345 NCBI chr25:30,690,959...30,801,484
Ensembl chr25:30,693,571...30,801,486 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12925702) InterPro
MGI		 PMID:12925702 GO_REF:0000002 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G EDN1 endothelin 1 acts_upstream_of_or_within ISO (PMID:8010105) RGD
MGI		 PMID:8010105 PMID:8893723 PMID:12396026 RGD:1581797 RGD:8662282 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G EDN2 endothelin 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:2768235) RGD
Ensembl
MGI		 PMID:2768235 PMID:12396026 GO_REF:0000107 RGD:1581797 NCBI chr15:1,647,966...1,654,272
Ensembl chr15:1,648,077...1,654,272 		JBrowse link
G F2R coagulation factor II thrombin receptor ISO RGD PMID:14699501 RGD:1582292 NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687 		JBrowse link
G ITGA2 integrin subunit alpha 2 ISO SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 4:62,170,137...62,268,962
Ensembl chr 4:62,170,452...62,268,983 		JBrowse link
G LOC611347 uncharacterized LOC611347 involved_in ISO PMID:3178840 RGD
UniProt		 PMID:3178840 PMID:16474416 RGD:13461757 RGD:1642122 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921 		JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NMU neuromedin U involved_in IEA TreeGrafter GO_REF:0000118
G NPNT nephronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:26,706,147...26,781,792
Ensembl chr32:26,705,476...26,781,275 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr15:52,790,136...52,797,785
Ensembl chr15:52,794,671...52,795,818 		JBrowse link
G PROK2 prokineticin 2 involved_in IEA Ensembl GO_REF:0000107
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17379756 RGD:1642962 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
G SRF serum response factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533 		JBrowse link
G TBXA2R thromboxane A2 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12925702) Ensembl
MGI		 PMID:12925702 GO_REF:0000107 NCBI chr20:55,819,866...55,829,395
Ensembl chr20:55,824,410...55,828,980 		JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:18562635 RGD:10043314 NCBI chr 6:74,932,789...74,986,573 JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC611347 uncharacterized LOC611347 involved_in ISO PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921 		JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11507009) Ensembl
MGI		 PMID:11507009 GO_REF:0000107 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO RGD PMID:32706268 RGD:38549369 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr 6:33,385,779...33,471,348
Ensembl chr 6:33,376,996...33,471,326 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO RGD PMID:17664026 PMID:19634638 RGD:2313546 RGD:6893570 NCBI chr17:34,615,121...34,618,480
Ensembl chr17:34,615,096...34,656,791 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:19208792 RGD:2316554 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19164477 RGD:2303954 NCBI chr24:18,193,381...18,194,232
Ensembl chr24:18,193,339...18,194,170 		JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:19164477 RGD:2303954 NCBI chr20:9,358,797...9,382,308
Ensembl chr20:9,358,916...9,378,343 		JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:12390879 RGD:2305937 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971 		JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12390879 RGD:2305937 NCBI chr 4:20,518,797...20,531,118
Ensembl chr 4:20,517,563...20,531,867 		JBrowse link
G TACR3 tachykinin receptor 3 ISO RGD PMID:12390879 RGD:2305937 NCBI chr32:24,812,344...24,888,452
Ensembl chr32:24,812,119...24,907,580 		JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:8428203 RGD:2303387 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:22158624) BHF-UCL PMID:22158624 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G RHOA ras homolog family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24335996) Ensembl
MGI		 PMID:24335996 GO_REF:0000107 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    positive regulation of biological process 6606
      positive regulation of multicellular organismal process 1869
        positive regulation of muscle contraction 53
          positive regulation of smooth muscle contraction + 37
          positive regulation of striated muscle contraction + 15
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of multicellular organismal process 3298
          regulation of system process 672
            regulation of muscle system process 287
              regulation of muscle contraction 179
                positive regulation of muscle contraction 53
                  positive regulation of smooth muscle contraction + 37
                  positive regulation of striated muscle contraction + 15
paths to the root