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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of muscle contraction
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Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction

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positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO (PMID:15459207) CAFA PMID:15459207 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chrNW_004955450:9,181,851...9,205,277
Ensembl chrNW_004955450:9,181,851...9,239,648 		JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in ISO (MGI:2181229|PMID:12075344) BHF-UCL PMID:12075344 MGI:2181229 NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chrNW_004955403:49,394,173...49,485,881
Ensembl chrNW_004955403:49,399,127...49,485,934 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480 		JBrowse link
G Chga chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chrNW_004955438:15,092,267...15,104,321
Ensembl chrNW_004955438:15,092,394...15,104,381 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chrNW_004955538:1,469,544...1,475,010
Ensembl chrNW_004955538:1,469,544...1,475,019 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chrNW_004955422:14,212,563...14,544,556
Ensembl chrNW_004955422:14,212,553...14,544,556 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003 		JBrowse link
G Rgs2 regulator of G protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022), (MGI:5009116|PMID:21291891) BHF-UCL PMID:19127022 PMID:21291891 MGI:3836877 MGI:5009116 NCBI chrNW_004955406:30,261,757...30,265,389
Ensembl chrNW_004955406:30,261,757...30,266,005 		JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO (MGI:4437553|PMID:18678771) MGI PMID:18678771 MGI:4437553 NCBI chrNW_004955455:5,271,615...5,294,151
Ensembl chrNW_004955455:5,273,602...5,297,604 		JBrowse link
G Ucn urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641 		JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17322067 RGD:12910822 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:24170253 RGD:10043193 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3778600|PMID:18178581) UniProt PMID:18178581 MGI:3778600 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO (PMID:12479237) UniProt PMID:12479237 NCBI chrNW_004955493:6,559,995...6,578,461
Ensembl chrNW_004955493:6,559,995...6,578,461 		JBrowse link
G Mylk2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chrNW_004955422:29,141,699...29,154,927
Ensembl chrNW_004955422:29,141,348...29,154,927 		JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 RGD:12907565 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812 		JBrowse link
G Ptafr platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chrNW_004955452:7,309,854...7,345,579
Ensembl chrNW_004955452:7,311,901...7,312,929 		JBrowse link
G Spx spexin hormone involved_in ISO (PMID:17284679) UniProt PMID:17284679 NCBI chrNW_004955413:17,173,215...17,178,388
Ensembl chrNW_004955413:17,173,215...17,178,388 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710 		JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:9832052 RGD:12910753 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812 		JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chrNW_004955420:2,483,173...2,486,414
Ensembl chrNW_004955420:2,478,877...2,487,215 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (MGI:3794903|PMID:18340377) MGI PMID:18340377 MGI:3794903 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in ISO (MGI:4947862|PMID:21335239) RGD
BHF-UCL		 PMID:19041301 PMID:21335239 MGI:4947862 RGD:5688345 NCBI chrNW_004955403:49,394,173...49,485,881
Ensembl chrNW_004955403:49,399,127...49,485,934 		JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) MGI PMID:12925702 MGI:2672939 NCBI chrNW_004955492:958,347...1,429,832
Ensembl chrNW_004955492:958,949...960,721 		JBrowse link
G Cttn cortactin involved_in ISO (PMID:24700464) UniProt PMID:24700464 NCBI chrNW_004955422:15,838,036...15,874,067
Ensembl chrNW_004955422:15,835,145...15,874,108 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO (MGI:66444|PMID:8010105) RGD
MGI		 PMID:8010105 PMID:8893723 PMID:12396026 MGI:66444 RGD:1581797 RGD:8662282 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Edn2 endothelin 2 acts_upstream_of_or_within ISO (MGI:65983|PMID:2768235) RGD
MGI		 PMID:2768235 PMID:12396026 MGI:65983 RGD:1581797 NCBI chrNW_004955537:1,228,062...1,233,784
Ensembl chrNW_004955537:1,228,070...1,233,797 		JBrowse link
G F2r coagulation factor II thrombin receptor ISO RGD PMID:14699501 RGD:1582292 NCBI chrNW_004955425:24,144,905...24,164,498 JBrowse link
G Itga2 integrin subunit alpha 2 ISO SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170 		JBrowse link
G Myocd myocardin involved_in ISO (PMID:17215356) BHF-UCL PMID:17215356 NCBI chrNW_004955467:4,653,065...4,743,438
Ensembl chrNW_004955467:4,656,380...4,743,110 		JBrowse link
G Nmu neuromedin U involved_in ISO PMID:3178840 RGD
UniProt		 PMID:3178840 PMID:16474416 RGD:13461757 RGD:1642122 NCBI chrNW_004955447:15,324,702...15,361,726
Ensembl chrNW_004955447:15,328,973...15,357,830 		JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4947862|PMID:21335239) BHF-UCL PMID:21335239 MGI:4947862 NCBI chrNW_004955496:3,321,310...3,388,625
Ensembl chrNW_004955496:3,320,946...3,388,694 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chrNW_004955471:11,796,278...11,804,114
Ensembl chrNW_004955471:11,796,278...11,804,114 		JBrowse link
G Prok2 prokineticin 2 involved_in ISO (PMID:11259612) UniProt PMID:11259612 NCBI chrNW_004955421:16,325,519...16,339,458
Ensembl chrNW_004955421:16,325,519...16,337,980 		JBrowse link
G Ptafr platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chrNW_004955452:7,309,854...7,345,579
Ensembl chrNW_004955452:7,311,901...7,312,929 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 RGD:2300247 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:17379756 RGD:1642962 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:12847068) UniProt PMID:12847068 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988 		JBrowse link
G Srf serum response factor involved_in ISO (PMID:17215356) BHF-UCL PMID:17215356 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) MGI PMID:12925702 MGI:2672939 NCBI chrNW_004955495:5,539,382...5,557,441
Ensembl chrNW_004955495:5,539,889...5,557,441 		JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:18562635 RGD:10043314 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in ISO PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chrNW_004955447:15,324,702...15,361,726
Ensembl chrNW_004955447:15,328,973...15,357,830 		JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO (MGI:3688972|PMID:11507009) MGI PMID:11507009 MGI:3688972 NCBI chrNW_004955435:19,537,224...19,563,631
Ensembl chrNW_004955435:19,536,634...19,564,580 		JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 ISO RGD PMID:32706268 RGD:38549369 NCBI chrNW_004955455:8,744,865...8,781,644
Ensembl chrNW_004955455:8,744,176...8,783,741 		JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chrNW_004955442:9,422,849...9,516,054
Ensembl chrNW_004955442:9,422,849...9,516,103 		JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:17664026 PMID:19634638 RGD:2313546 RGD:6893570 NCBI chrNW_004955470:3,711,075...3,714,450
Ensembl chrNW_004955470:3,711,031...3,714,241 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:21427217) UniProt PMID:21427217 NCBI chrNW_004955460:8,790,798...8,794,902
Ensembl chrNW_004955460:8,790,798...8,794,902 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:19208792 RGD:2316554 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310 		JBrowse link
G Oxtr oxytocin receptor ISO RGD PMID:19164477 RGD:2303954 NCBI chrNW_004955561:340,387...354,499
Ensembl chrNW_004955561:337,902...354,336 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:12390879 RGD:2305937 NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872 		JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:12390879 RGD:2305937 NCBI chrNW_004955437:21,719,246...21,731,963
Ensembl chrNW_004955437:21,719,246...21,731,963 		JBrowse link
G Tacr3 tachykinin receptor 3 ISO RGD PMID:12390879 RGD:2305937 NCBI chrNW_004955496:5,152,134...5,222,565
Ensembl chrNW_004955496:5,151,668...5,222,624 		JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor muscarinic 3 ISO RGD PMID:8428203 RGD:2303387 NCBI chrNW_004955492:958,347...1,429,832
Ensembl chrNW_004955492:958,949...960,721 		JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (MGI:5638847|PMID:24335996) MGI PMID:24335996 MGI:5638847 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12243
    positive regulation of biological process 5628
      positive regulation of multicellular organismal process 1514
        positive regulation of muscle contraction 50
          positive regulation of smooth muscle contraction + 34
          positive regulation of striated muscle contraction + 15
Path 2
Term Annotations click to browse term
  biological_process 12243
    biological regulation 9029
      regulation of biological process 8547
        regulation of multicellular organismal process 2683
          regulation of system process 633
            regulation of muscle system process 256
              regulation of muscle contraction 160
                positive regulation of muscle contraction 50
                  positive regulation of smooth muscle contraction + 34
                  positive regulation of striated muscle contraction + 15
paths to the root