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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of muscle contraction
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Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction


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positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G CCN2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CHGA chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr14:73,555,834...73,568,547
Ensembl chr14:92,895,450...92,908,159 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chr11:2,469,750...2,874,467 JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955 		JBrowse link
G SMTN smoothelin acts_upstream_of_or_within ISO (MGI:4437553|PMID:18678771) MGI PMID:18678771 MGI:4437553 NCBI chr22:12,105,016...12,128,365
Ensembl chr22:29,942,895...29,966,256 		JBrowse link
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669 		JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17322067 RGD:12910822 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:24170253 RGD:10043193 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,265,516...29,290,807
Ensembl chr16:29,265,516...29,290,807 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508 		JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 RGD:12907565 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G SPX spexin hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,766,136...64,771,728
Ensembl chr12:67,369,413...67,375,630 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19258489 RGD:2304084 NCBI chr20:3,157,246...3,159,013 JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:9832052 RGD:12910753 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3794903|PMID:18340377) MGI
Ensembl		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO
IEA		 RGD
Ensembl		 PMID:19041301 GO_REF:0000107 RGD:5688345 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) MGI PMID:12925702 MGI:2672939 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857 		JBrowse link
G EDN1 endothelin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:66444|PMID:8010105) RGD
Ensembl
MGI		 PMID:8010105 PMID:8893723 PMID:12396026 GO_REF:0000107 MGI:66444 RGD:1581797 RGD:8662282 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EDN2 endothelin 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:65983|PMID:2768235) RGD
Ensembl
MGI		 PMID:2768235 PMID:12396026 GO_REF:0000107 MGI:65983 RGD:1581797 NCBI chr 1:40,777,582...40,783,410
Ensembl chr 1:42,092,811...42,098,721 		JBrowse link
G F2R coagulation factor II thrombin receptor ISO RGD PMID:14699501 RGD:1582292 NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G ITGA2 integrin subunit alpha 2 ISO SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659 		JBrowse link
G NMU neuromedin U involved_in ISO PMID:3178840 RGD
UniProt		 PMID:3178840 PMID:16474416 RGD:13461757 RGD:1642122 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
G NPNT nephronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,365,727...98,445,746
Ensembl chr 4:108,974,971...109,054,671 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231 		JBrowse link
G PROK2 prokineticin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:71,711,334...71,724,865
Ensembl chr 3:73,068,599...73,080,897 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17379756 RGD:1642962 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G SRF serum response factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768 		JBrowse link
G TBXA2R thromboxane A2 receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2672939|PMID:12925702) MGI
Ensembl		 PMID:12925702 GO_REF:0000107 MGI:2672939 NCBI chr19:2,621,606...2,632,800
Ensembl chr19:3,570,290...3,581,924 		JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:18562635 RGD:10043314 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NMU neuromedin U involved_in ISO PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3688972|PMID:11507009) MGI
Ensembl		 PMID:11507009 GO_REF:0000107 MGI:3688972 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO RGD PMID:32706268 RGD:38549369 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO RGD PMID:17664026 PMID:19634638 RGD:2313546 RGD:6893570 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:19208792 RGD:2316554 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 involved_in ISO (PMID:21427217) UniProt PMID:21427217 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19164477 RGD:2303954 NCBI chr20:3,157,246...3,159,013 JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:19164477 RGD:2303954 NCBI chr 3:8,701,344...8,721,706 JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:12390879 RGD:2305937 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018 		JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12390879 RGD:2305937 NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224 		JBrowse link
G TACR3 tachykinin receptor 3 ISO RGD PMID:12390879 RGD:2305937 NCBI chr 4:96,022,788...96,162,249
Ensembl chr 4:106,644,943...106,776,172 		JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:8428203 RGD:2303387 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G RHOA ras homolog family member A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5638847|PMID:24335996) MGI
Ensembl		 PMID:24335996 GO_REF:0000107 MGI:5638847 NCBI chr 3:49,282,009...49,339,887 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15365
    positive regulation of biological process 6036
      positive regulation of multicellular organismal process 1622
        positive regulation of muscle contraction 51
          positive regulation of smooth muscle contraction + 35
          positive regulation of striated muscle contraction + 15
Path 2
Term Annotations click to browse term
  biological_process 15365
    biological regulation 10992
      regulation of biological process 10398
        regulation of multicellular organismal process 2868
          regulation of system process 658
            regulation of muscle system process 266
              regulation of muscle contraction 168
                positive regulation of muscle contraction 51
                  positive regulation of smooth muscle contraction + 35
                  positive regulation of striated muscle contraction + 15
paths to the root