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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of muscle contraction
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Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction



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positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP
PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:2181229|PMID:12075344)
Ensembl
RGD
PMID:12075344 GO_REF:0000107 MGI:2181229 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19707545 RGD:2314476 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Chga chromogranin A involved_in IDA PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP RGD PMID:21620734 RGD:5686387 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19646991)
Ensembl
RGD
PMID:19646991 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:19646991) RGD PMID:19646991 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022), (MGI:5009116|PMID:21291891) RGD PMID:19127022 PMID:21291891 MGI:3836877 MGI:5009116 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO MGI:3613292|MGI:3613293 (MGI:4437553|PMID:18678771) RGD PMID:18678771 MGI:4437553 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:17322067 RGD:12910822 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:24170253 RGD:10043193 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3778600|PMID:18178581) RGD PMID:18178581 MGI:3778600 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
ISS
(PMID:12479237)
GO_REF:0000024
RGD
UniProt
PMID:12479237 GO_REF:0000024 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Mylk2 myosin light chain kinase 2 IMP RGD PMID:12748068 RGD:1580242 NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728
JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 RGD:12907565 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Spx spexin hormone involved_in ISO
IBA
ISS
(PMID:17284679)
PMID:21873635
RGD PMID:17284679 PMID:21873635 PMID:17284679 RGD:13792537, RGD:12907558 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082
JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:9832052 RGD:12910753 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir1 microRNA 1 involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir1b microRNA 1b involved_in ISO (PMID:19131648) RGD PMID:19131648 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201
JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 PMID:21874246 RGD:12907565, RGD:12910732 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:7542218 RGD:12910748 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3794903|PMID:18340377) RGD PMID:18340377 MGI:3794903 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP
ISO
(MGI:4947862|PMID:21335239) RGD PMID:21335239 PMID:19041301 MGI:4947862, RGD:5688345 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) RGD PMID:12925702 MGI:2672939 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Cttn cortactin involved_in ISO
IEA
UniProtKB:P07737 (PMID:24700464)
GO_REF:0000107
RGD
Ensembl
PMID:24700464 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within IDA
ISO
IMP
(MGI:66444|PMID:8010105) RGD PMID:8010105 PMID:12396026 PMID:8893723 MGI:66444, RGD:1581797, RGD:8662282 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
(MGI:65983|PMID:2768235)
GO_REF:0000107
RGD
Ensembl
PMID:2768235 PMID:12396026 GO_REF:0000107 MGI:65983, RGD:1581797 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA RGD PMID:14699501 RGD:1582292 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Itga2 integrin subunit alpha 2 IMP SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Myocd myocardin involved_in ISO
IEA
(PMID:17215356)
GO_REF:0000107
RGD
Ensembl
PMID:17215356 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nmu neuromedin U involved_in IMP
IBA
IDA
PMID:21873635
PMID:3178840
RGD
GO_Central
UniProt
PMID:16474416 PMID:21873635 PMID:3178840 RGD:1642122, RGD:13792537, RGD:13461757 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4947862|PMID:21335239) RGD PMID:21335239 MGI:4947862 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Prok2 prokineticin 2 involved_in ISO (PMID:11259612) RGD PMID:11259612 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18480553 RGD:2300247 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18480553 RGD:2300247 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17379756 RGD:1642962 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
(PMID:12847068)
GO_REF:0000107
RGD
Ensembl
PMID:12847068 GO_REF:0000107 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Srf serum response factor involved_in ISO (PMID:17215356) RGD PMID:17215356 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) RGD PMID:12925702 MGI:2672939 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:18562635 RGD:10043314 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO MGI:2451290 (MGI:3688972|PMID:11507009) RGD PMID:11507009 MGI:3688972 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 IMP RGD PMID:32706268 RGD:38549369 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:19634638 PMID:17664026 RGD:2313546, RGD:6893570 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
ISS
(PMID:21427217)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21427217 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase IMP RGD PMID:19208792 RGD:2316554 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19164477 RGD:2303954 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:19164477 RGD:2303954 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
G Tacr1 tachykinin receptor 1 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tacr2 tachykinin receptor 2 IDA RGD PMID:12390879 RGD:2305937 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:8428203 RGD:2303387 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    positive regulation of biological process 6796
      positive regulation of multicellular organismal process 1752
        positive regulation of muscle contraction 54
          positive regulation of smooth muscle contraction + 36
          positive regulation of striated muscle contraction + 17
Path 2
Term Annotations click to browse term
  biological_process 20091
    biological regulation 13996
      regulation of biological process 13218
        regulation of multicellular organismal process 3165
          regulation of system process 698
            regulation of muscle system process 279
              regulation of muscle contraction 177
                positive regulation of muscle contraction 54
                  positive regulation of smooth muscle contraction + 36
                  positive regulation of striated muscle contraction + 17
paths to the root