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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of muscle contraction
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Accession:GO:0045932 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: down regulation of muscle contraction;   downregulation of muscle contraction
 narrow_synonym: inhibition of muscle contraction



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negative regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnt1 troponin T1, slow skeletal type involved_in ISO (PMID:18032382) RGD PMID:18032382 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde5a phosphodiesterase 5A involved_in IEA
ISO
GO_REF:0000107
(MGI:3836877|PMID:19127022)
Ensembl
RGD
PMID:19127022 GO_REF:0000107 MGI:3836877 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Sri sorcin involved_in ISO (MGI:5319286|PMID:22326846) RGD PMID:22326846 MGI:5319286 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:5142149|PMID:21616078)
UniProt
RGD
PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IDA RGD PMID:17543276 RGD:10398727 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
negative regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IMP RGD PMID:23647678 RGD:10412032 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
negative regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18306009 RGD:5129131 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:88398|MGI:98496 (MGI:2672939|PMID:12925702)
PMID:21873635
Ensembl
RGD
PMID:12925702 PMID:21873635 GO_REF:0000107 MGI:2672939, RGD:13792537 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within IMP
ISO
(MGI:1098356|PMID:9322931) RGD PMID:9322931 PMID:11230364 MGI:1098356, RGD:68890 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calcrl calcitonin receptor like receptor IMP RGD PMID:17363466 RGD:1625357 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:1934143 (MGI:3771783|PMID:17993584) RGD PMID:17993584 MGI:3771783 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21051526 RGD:5135055 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
negative regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO MGI:2451291 (MGI:3688972|PMID:11507009) RGD PMID:11507009 MGI:3688972 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
ISS
(PMID:10914677)
GO_REF:0000024
RGD
UniProt
PMID:10914677 GO_REF:0000024 NCBI chr 1:181,026,606...181,044,859 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in ISO
IEA
(PMID:15051637)
GO_REF:0000107
RGD
Ensembl
PMID:15051637 GO_REF:0000107 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
negative regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:17664026 RGD:6893570 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adra2c adrenoceptor alpha 2C IMP RGD PMID:17664026 RGD:6893570 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap42 Rho GTPase activating protein 42 acts_upstream_of_or_within ISO MGI:3871380 (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870
JBrowse link
G Dock4 dedicator of cytokinesis 4 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855
JBrowse link
G Dock5 dedicator of cytokinesis 5 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5583915|PMID:24836577)
Ensembl
RGD
PMID:24836577 GO_REF:0000107 MGI:5583915 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
relaxation of vascular associated smooth muscle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IMP RGD PMID:19443947 RGD:2317917 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2b adenosine A2B receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)
Ensembl
RGD
PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3640802 (MGI:3640061|PMID:16614755)
Ensembl
RGD
PMID:16614755 GO_REF:0000107 MGI:3640061 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3050114 (MGI:3695011|PMID:15867178)
(PMID:25139746)
RGD PMID:15867178 PMID:25139746 PMID:21873635 MGI:3695011, RGD:13792537 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:2682081|PMID:14608379) RGD PMID:14608379 MGI:2682081 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857873 (MGI:2682495|PMID:14679182), (MGI:3625573|PMID:12433839)
UniProt
RGD
PMID:12433839 PMID:14679182 GO_REF:0000024 MGI:2682495 MGI:3625573 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
smooth muscle relaxation of the bladder outlet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Pgr progesterone receptor involved_in ISO (PMID:24296318) RGD PMID:24296318 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    negative regulation of biological process 5612
      negative regulation of multicellular organismal process 1135
        negative regulation of muscle contraction 33
          negative regulation of muscle filament sliding 1
          negative regulation of smooth muscle contraction + 23
          negative regulation of striated muscle contraction + 8
Path 2
Term Annotations click to browse term
  biological_process 19494
    biological regulation 13507
      regulation of biological process 12763
        regulation of multicellular organismal process 2921
          regulation of system process 663
            regulation of muscle system process 266
              regulation of muscle contraction 169
                negative regulation of muscle contraction 33
                  negative regulation of muscle filament sliding 1
                  negative regulation of smooth muscle contraction + 23
                  negative regulation of striated muscle contraction + 8
paths to the root