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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of muscle contraction
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Accession:GO:0045932 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: down regulation of muscle contraction;   downregulation of muscle contraction
 narrow_synonym: inhibition of muscle contraction


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negative regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnt1 troponin T1, slow skeletal type involved_in ISO (PMID:18032382) RGD PMID:18032382 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31754830 RGD:329403060 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde5a phosphodiesterase 5A involved_in ISO (MGI:3836877|PMID:19127022) RGD PMID:19127022 MGI:3836877 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Sri sorcin involved_in ISO (MGI:5319286|PMID:22326846) RGD PMID:22326846 MGI:5319286 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5142149|PMID:21616078)		 UniProt
RGD		 PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IDA RGD PMID:17543276 RGD:10398727 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
negative regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IMP RGD PMID:23647678 RGD:10412032 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18306009 RGD:5129131 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:88398|MGI:98496 (MGI:2672939|PMID:12925702)		 RGD PMID:12925702 PMID:21873635 MGI:2672939, RGD:13792537 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within IMP
ISO		 (MGI:1098356|PMID:9322931) RGD PMID:9322931 PMID:11230364 MGI:1098356, RGD:68890 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calcrl calcitonin receptor like receptor IMP RGD PMID:17363466 RGD:1625357 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:1934143 (MGI:3771783|PMID:17993584) RGD PMID:17993584 MGI:3771783 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21051526 RGD:5135055 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
negative regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO MGI:2451291 (MGI:3688972|PMID:11507009) RGD PMID:11507009 MGI:3688972 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
ISS		 (PMID:10914677)
GO_REF:0000024		 RGD
UniProt		 PMID:10914677 GO_REF:0000024 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in ISO
IEA		 (PMID:15051637)
GO_REF:0000107		 RGD
Ensembl		 PMID:15051637 GO_REF:0000107 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
negative regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:17664026 RGD:6893570 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2c adrenoceptor alpha 2C IMP RGD PMID:17664026 RGD:6893570 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap42 Rho GTPase activating protein 42 acts_upstream_of_or_within ISO MGI:3871380 (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Dock4 dedicator of cytokinesis 4 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855 		JBrowse link
G Dock5 dedicator of cytokinesis 5 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649 		JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583915|PMID:24836577)		 Ensembl
RGD		 PMID:24836577 GO_REF:0000107 MGI:5583915 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
relaxation of vascular associated smooth muscle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)		 Ensembl
RGD		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3640802 (MGI:3640061|PMID:16614755)		 Ensembl
RGD		 PMID:16614755 GO_REF:0000107 MGI:3640061 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:25139746)
MGI:3050114 (MGI:3695011|PMID:15867178)		 RGD PMID:15867178 PMID:25139746 MGI:3695011 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:2682081|PMID:14608379) RGD PMID:14608379 MGI:2682081 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857873 (MGI:2682495|PMID:14679182), (MGI:3625573|PMID:12433839)		 UniProt
RGD		 PMID:12433839 PMID:14679182 GO_REF:0000024 MGI:2682495 MGI:3625573 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr 8:96,263,322...96,314,197
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
smooth muscle relaxation of the bladder outlet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Pgr progesterone receptor involved_in ISO (PMID:24296318) RGD PMID:24296318 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    negative regulation of biological process 5782
      negative regulation of multicellular organismal process 1353
        negative regulation of muscle contraction 34
          negative regulation of muscle filament sliding 1
          negative regulation of smooth muscle contraction + 23
          negative regulation of striated muscle contraction + 9
Path 2
Term Annotations click to browse term
  biological_process 19738
    biological regulation 13436
      regulation of biological process 13021
        regulation of multicellular organismal process 3355
          regulation of system process 668
            regulation of muscle system process 279
              regulation of muscle contraction 175
                negative regulation of muscle contraction 34
                  negative regulation of muscle filament sliding 1
                  negative regulation of smooth muscle contraction + 23
                  negative regulation of striated muscle contraction + 9
paths to the root