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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of fatty acid metabolic process
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Accession:GO:0045922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
Synonyms:exact_synonym: down regulation of fatty acid metabolic process;   downregulation of fatty acid metabolic process;   negative regulation of fatty acid metabolism
 narrow_synonym: inhibition of fatty acid metabolic process


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negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 involved_in ISO (PMID:1184755) RGD PMID:1184755 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA		 (PMID:19955185)
GO_REF:0000107		 RGD
Ensembl		 PMID:19955185 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:24769897)
(MGI:6212098|PMID:24769897)		 RGD PMID:24769897 MGI:6212098 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:3530688|PMID:15677334), (MGI:3629477|PMID:12920182) RGD PMID:12920182 PMID:15677334 MGI:3530688 MGI:3629477 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:16814735)
GO_REF:0000107		 RGD
Ensembl		 PMID:16814735 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19724020 RGD:2314644 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Dbi diazepam binding inhibitor IDA RGD PMID:11485163 RGD:2316274 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Pink1 PTEN induced kinase 1 HMP RGD PMID:25421206 RGD:11560775 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5440401|PMID:22532565), (MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)		 UniProt
RGD		 PMID:21885430 PMID:22532565 PMID:22675471 GO_REF:0000024 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120 		JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO
ISS		 (PMID:25416781)
GO_REF:0000024
(MGI:5700285|PMID:25023281)		 RGD
UniProt		 PMID:25023281 PMID:25416781 GO_REF:0000024 MGI:5700285 NCBI chr 4:182,140,492...182,204,635
Ensembl chr 4:182,140,559...182,150,305 		JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO		 GO_REF:0000107
(MGI:3526480|PMID:15639194)		 Ensembl
RGD		 PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:11060345), (PMID:18635818) RGD PMID:11060345 PMID:18635818 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
ISS		 (PMID:16326698)
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024		 RGD
TreeGrafter
Ensembl
UniProt		 PMID:16326698 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:99,171,506...99,260,183
Ensembl chr 6:99,171,506...99,260,110 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (PMID:16100574) RGD PMID:16100574 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1916289 (PMID:16100574)		 Ensembl
RGD		 PMID:16100574 GO_REF:0000107 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO (PMID:27664236) RGD PMID:27664236 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir30c1 microRNA 30c-1 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325 		JBrowse link
G Mir30c2 microRNA 30c-2 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (MGI:3630230|PMID:16794074) RGD PMID:16794074 MGI:3630230 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23932781)		 Ensembl
RGD		 PMID:23932781 GO_REF:0000107 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784 		JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:17767906)		 GO_Central
RGD		 PMID:17767906 GO_REF:0000033 NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408 		JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:1932690|PMID:11283375), (MGI:3804564|PMID:18487439) RGD PMID:11283375 PMID:18487439 MGI:1932690 MGI:3804564 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO		 GO_REF:0000107
(MGI:3526480|PMID:15639194)		 Ensembl
RGD		 PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) RGD PMID:19661063 MGI:4420367 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO MGI:1916776|MGI:2429497 (PMID:24792439) RGD PMID:24792439 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1310002|MGI:2429497 (PMID:24792439)		 Ensembl
RGD		 PMID:24792439 GO_REF:0000107 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO MGI:1310002|MGI:1916776 (PMID:24792439) RGD PMID:24792439 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of_or_within ISO (PMID:24011070) RGD PMID:24011070 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir214 microRNA 214 acts_upstream_of_or_within ISO (PMID:24011070) RGD PMID:24011070 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(MGI:5501374|PMID:23746352), (MGI:5547879|PMID:24043310)		 RGD PMID:23746352 PMID:24043310 MGI:5501374 MGI:5547879 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414737|PMID:32103177)		 UniProt
RGD		 PMID:32103177 GO_REF:0000024 MGI:6414737 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5306564|PMID:20042607)
GO_REF:0000107		 RGD
Ensembl		 PMID:20042607 GO_REF:0000107 MGI:5306564 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    negative regulation of biological process 5812
      negative regulation of cellular process 5413
        negative regulation of cellular metabolic process 2778
          negative regulation of fatty acid metabolic process 44
            negative regulation of butyryl-CoA catabolic process to butanol 0
            negative regulation of fatty acid biosynthetic process + 23
            negative regulation of fatty acid oxidation + 19
            negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
            negative regulation of palmitic acid catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      small molecule metabolic process 1952
        organic acid metabolic process 1077
          oxoacid metabolic process 1059
            carboxylic acid metabolic process 1040
              monocarboxylic acid metabolic process 770
                fatty acid metabolic process 467
                  regulation of fatty acid metabolic process 116
                    negative regulation of fatty acid metabolic process 44
                      negative regulation of butyryl-CoA catabolic process to butanol 0
                      negative regulation of fatty acid biosynthetic process + 23
                      negative regulation of fatty acid oxidation + 19
                      negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
                      negative regulation of palmitic acid catabolic process 0
paths to the root