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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of fatty acid metabolic process
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Accession:GO:0045922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
Synonyms:exact_synonym: down regulation of fatty acid metabolic process;   downregulation of fatty acid metabolic process;   negative regulation of fatty acid metabolism
 narrow_synonym: inhibition of fatty acid metabolic process


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negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins insulin involved_in ISO (PMID:1184755) BHF-UCL PMID:1184755 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842
JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:24769897)
(MGI:6212098|PMID:24769897)
UniProt PMID:24769897 MGI:6212098 NCBI chrNW_004955421:5,027,568...5,040,000 JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:3530688|PMID:15677334), (MGI:3629477|PMID:12920182) UniProt PMID:12920182 PMID:15677334 MGI:3530688 MGI:3629477 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chrNW_004955459:10,342,528...10,347,700
Ensembl chrNW_004955459:10,342,251...10,347,733
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) ARUK-UCL PMID:23209793 MGI:5474727 NCBI chrNW_004955452:17,430,850...17,443,830
Ensembl chrNW_004955452:17,430,219...17,443,830
JBrowse link
G Pink1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125
JBrowse link
G Plin5 perilipin 5 involved_in ISO (MGI:5440401|PMID:22532565)
(MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)
UniProt PMID:21885430 PMID:22532565 PMID:22675471 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chrNW_004955495:4,406,590...4,414,783
Ensembl chrNW_004955495:4,407,246...4,416,848
JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO (PMID:25416781)
(MGI:5700285|PMID:25023281)
UniProt PMID:25023281 PMID:25416781 MGI:5700285 NCBI chrNW_004955411:35,999,583...36,025,805 JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chrNW_004955457:5,266,032...5,300,632
Ensembl chrNW_004955457:5,266,033...5,300,056
JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chrNW_004955467:9,684,070...9,689,454
Ensembl chrNW_004955467:9,684,250...9,689,356
JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:11060345), (PMID:18635818) BHF-UCL PMID:11060345 PMID:18635818 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:16326698) UniProt PMID:16326698 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955507:6,029,247...6,062,946
Ensembl chrNW_004955507:6,028,324...6,063,689
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955463:13,445,468...13,460,370
Ensembl chrNW_004955463:13,444,722...13,463,132
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955491:8,333,624...8,344,658
Ensembl chrNW_004955491:8,335,359...8,344,658
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955459:11,571,582...11,596,069
Ensembl chrNW_004955459:11,571,145...11,592,146
JBrowse link
G Klhl25 kelch like family member 25 involved_in ISO (PMID:27664236) UniProt PMID:27664236 NCBI chrNW_004955416:18,965,966...18,991,099 JBrowse link
G LOC102008593 cholesterol 7-alpha-monooxygenase involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chrNW_004955454:17,035,105...17,078,854
Ensembl chrNW_004955454:17,036,204...17,042,756
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (MGI:3630230|PMID:16794074) BHF-UCL PMID:16794074 MGI:3630230 NCBI chrNW_004955597:259,209...265,896
Ensembl chrNW_004955597:260,790...265,326
JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO (PMID:23932781) UniProt PMID:23932781 NCBI chrNW_004955527:57,335...185,727
Ensembl chrNW_004955527:57,335...185,727
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 acts_upstream_of_or_within ISO (PMID:17767906) MGI PMID:17767906 NCBI chrNW_004955452:6,519,628...6,581,333
Ensembl chrNW_004955452:6,519,629...6,581,333
JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:1932690|PMID:11283375), (MGI:3804564|PMID:18487439) UniProt PMID:11283375 PMID:18487439 MGI:1932690 MGI:3804564 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076
JBrowse link
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chrNW_004955457:5,266,032...5,300,632
Ensembl chrNW_004955457:5,266,033...5,300,056
JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (MGI:3526480|PMID:15639194) BHF-UCL PMID:15639194 MGI:3526480 NCBI chrNW_004955467:9,684,070...9,689,454
Ensembl chrNW_004955467:9,684,250...9,689,356
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) UniProt PMID:19661063 MGI:4420367 NCBI chrNW_004955405:39,503,020...39,540,069
Ensembl chrNW_004955405:39,503,020...39,540,335
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004955414:16,059,781...16,089,727
Ensembl chrNW_004955414:16,059,781...16,089,727
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,882,656...11,915,875
Ensembl chrNW_004955406:11,881,882...11,916,323
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,851,694...11,875,314
Ensembl chrNW_004955406:11,851,637...11,876,843
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,967,045...11,987,105
Ensembl chrNW_004955406:11,967,003...11,988,887
JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(MGI:5547879|PMID:24043310)
(MGI:5501374|PMID:23746352)
UniProt PMID:23746352 PMID:24043310 MGI:5501374 MGI:5547879 NCBI chrNW_004955455:11,322,812...11,334,786
Ensembl chrNW_004955455:11,324,479...11,334,817
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (MGI:6414737|PMID:32103177) UniProt PMID:32103177 MGI:6414737 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) UniProt PMID:3863495 NCBI chrNW_004955404:33,713,903...33,897,622
Ensembl chrNW_004955404:33,714,193...33,897,622
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306564|PMID:20042607) UniProt PMID:20042607 MGI:5306564 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    negative regulation of biological process 4706
      negative regulation of cellular process 4379
        negative regulation of cellular metabolic process 2118
          negative regulation of fatty acid metabolic process 35
            negative regulation of butyryl-CoA catabolic process to butanol 0
            negative regulation of fatty acid biosynthetic process + 17
            negative regulation of fatty acid oxidation + 17
            negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
            negative regulation of palmitic acid catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      small molecule metabolic process 1297
        organic acid metabolic process 663
          oxoacid metabolic process 659
            carboxylic acid metabolic process 651
              monocarboxylic acid metabolic process 460
                fatty acid metabolic process 284
                  regulation of fatty acid metabolic process 98
                    negative regulation of fatty acid metabolic process 35
                      negative regulation of butyryl-CoA catabolic process to butanol 0
                      negative regulation of fatty acid biosynthetic process + 17
                      negative regulation of fatty acid oxidation + 17
                      negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
                      negative regulation of palmitic acid catabolic process 0
paths to the root