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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of fatty acid metabolic process
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Accession:GO:0045922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
Synonyms:exact_synonym: down regulation of fatty acid metabolic process;   downregulation of fatty acid metabolic process;   negative regulation of fatty acid metabolism
 narrow_synonym: inhibition of fatty acid metabolic process


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negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 involved_in ISO (PMID:1184755) RGD PMID:1184755 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G LOC685081 similar to solute carrier family 22 (organic cation transporter), member 13 involved_in ISO (PMID:24769897)
(MGI:6212098|PMID:24769897)
RGD PMID:24769897 MGI:6212098 NCBI chr 8:127,905,478...127,914,897
Ensembl chr 8:127,909,147...127,912,860
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA
(PMID:19955185)
GO_REF:0000107
RGD
Ensembl
PMID:19955185 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:3530688|PMID:15677334), (MGI:3629477|PMID:12920182) RGD PMID:12920182 PMID:15677334 MGI:3530688 MGI:3629477 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) RGD PMID:16814735 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19724020 RGD:2314644 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IDA RGD PMID:11485163 RGD:2316274 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440401|PMID:22532565), (MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:21885430 PMID:22532565 PMID:22675471 GO_REF:0000024 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO
ISS
(PMID:25416781)
GO_REF:0000024
(MGI:5700285|PMID:25023281)
RGD
UniProt
PMID:25023281 PMID:25416781 GO_REF:0000024 MGI:5700285 NCBI chr 4:183,655,968...183,665,757
Ensembl chr 4:183,656,013...183,665,754
JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:11060345), (PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:11060345 PMID:18635818 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
ISS
IBA
(PMID:16326698)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:16326698, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (MGI:3630230|PMID:16794074) RGD PMID:16794074 MGI:3630230 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3770497|PMID:17767906)
RGD PMID:17767906, PMID:21873635 MGI:3770497, RGD:13792537 NCBI chr 5:151,487,572...151,536,829
Ensembl chr 5:151,487,577...151,536,518
JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:1932690|PMID:11283375), (MGI:3804564|PMID:18487439) RGD PMID:11283375 PMID:18487439 MGI:1932690 MGI:3804564 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) RGD PMID:19661063 MGI:4420367 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of_or_within ISO (MGI:5528778|PMID:24011070) RGD PMID:24011070 MGI:5528778 NCBI chr13:80,125,487...80,125,596
Ensembl chr13:80,125,487...80,125,596
JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(MGI:5501374|PMID:23746352), (MGI:5547879|PMID:24043310)
RGD PMID:23746352 PMID:24043310 MGI:5501374 MGI:5547879 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414737|PMID:32103177)
UniProt
RGD
PMID:32103177 GO_REF:0000024 MGI:6414737 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306564|PMID:20042607) RGD PMID:20042607 MGI:5306564 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    negative regulation of biological process 5598
      negative regulation of cellular process 5092
        negative regulation of cellular metabolic process 2673
          negative regulation of fatty acid metabolic process 32
            negative regulation of butyryl-CoA catabolic process to butanol 0
            negative regulation of fatty acid biosynthetic process + 15
            negative regulation of fatty acid oxidation + 14
            negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
Path 2
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      small molecule metabolic process 1786
        organic acid metabolic process 1006
          oxoacid metabolic process 969
            carboxylic acid metabolic process 951
              monocarboxylic acid metabolic process 656
                fatty acid metabolic process 424
                  regulation of fatty acid metabolic process 102
                    negative regulation of fatty acid metabolic process 32
                      negative regulation of butyryl-CoA catabolic process to butanol 0
                      negative regulation of fatty acid biosynthetic process + 15
                      negative regulation of fatty acid oxidation + 14
                      negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
paths to the root