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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of exocytosis
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Accession:GO:0045920 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
Synonyms:exact_synonym: down regulation of exocytosis;   downregulation of exocytosis
 narrow_synonym: inhibition of exocytosis



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negative regulation of exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19625660)
UniProt
Ensembl
RGD
PMID:19625660 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 involved_in ISO
IBA
IDA
IEA
(PMID:12783849)
GO_REF:0000033
PMID:17502602
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:12783849 PMID:17502602 GO_REF:0000033 GO_REF:0000107, RGD:8553610 NCBI chr  X:51,371,969...52,876,726
Ensembl chr  X:51,378,215...52,876,772
JBrowse link
G Snca synuclein alpha involved_in ISO
IEA
(PMID:12239163)
GO_REF:0000107
RGD
Ensembl
PMID:12239163 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Tcp11 t-complex 11 involved_in ISO (PMID:9322250), (PMID:9820206) RGD PMID:9322250 PMID:9820206 NCBI chr20:6,126,267...6,138,408
Ensembl chr20:6,126,269...6,136,055
JBrowse link
negative regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in IMP PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein involved_in ISO (PMID:24751537) RGD PMID:24751537 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11533141 RGD:13508598 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2684314 (PMID:19251639) RGD PMID:19251639 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:2357966) RGD PMID:2357966 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IC PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO MGI:97852 (PMID:23616533) RGD PMID:23616533 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rest RE1-silencing transcription factor involved_in IMP PMID:21536750 UniProt PMID:21536750 RGD:8554180 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:12649283) RGD PMID:12649283 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671
JBrowse link
G Syt4 synaptotagmin 4 IDA RGD PMID:21551071 RGD:7205660 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
G Trim9 tripartite motif-containing 9 IMP RGD PMID:11524423 RGD:631246 NCBI chr 6:88,756,824...88,856,588
Ensembl chr 6:88,757,303...88,856,542
JBrowse link
negative regulation of constitutive secretory pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab33b RAB33B, member RAS oncogene family involved_in ISO (PMID:22899725) RGD PMID:22899725 NCBI chr 2:135,528,116...135,538,719
Ensembl chr 2:135,528,116...135,538,719
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in IMP PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:14662900)
BHF-UCL
RGD
PMID:14662900 GO_REF:0000024 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
negative regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp9a ATPase phospholipid transporting 9A (putative) involved_in ISO (PMID:30947313) RGD PMID:30947313 NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:26911690)
GO_REF:0000107
RGD
Ensembl
PMID:26911690 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:26911690) RGD PMID:26911690 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16339535)
(PMID:12874256)
RGD PMID:12874256 PMID:16339535 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:2179135 (PMID:18421012) RGD PMID:18421012 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2653910 (PMID:15944273)
Ensembl
RGD
PMID:15944273 GO_REF:0000107 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:15235600) RGD PMID:15235600 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:88141 (PMID:19703997) RGD PMID:19703997 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:107771 (PMID:19703997) RGD PMID:19703997 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:30911105) RGD PMID:30911105 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:23616533) RGD PMID:23616533 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:894315 (PMID:23616533)
GO_Central
RGD
PMID:23616533 GO_REF:0000033 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:97852 (PMID:23616533)
GO_Central
RGD
PMID:23616533 GO_REF:0000033 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (PMID:19448629) RGD PMID:19448629 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    cellular process 19130
      negative regulation of cellular process 5529
        negative regulation of secretion by cell 209
          negative regulation of exocytosis 37
            negative regulation of constitutive secretory pathway 1
            negative regulation of exocyst assembly 0
            negative regulation of exosomal secretion 4
            negative regulation of regulated secretory pathway + 28
Path 2
Term Annotations click to browse term
  biological_process 20052
    biological regulation 13542
      regulation of biological process 13122
        regulation of localization 2387
          regulation of transport 1948
            regulation of secretion 805
              regulation of secretion by cell 730
                negative regulation of secretion by cell 209
                  negative regulation of exocytosis 37
                    negative regulation of constitutive secretory pathway 1
                    negative regulation of exocyst assembly 0
                    negative regulation of exosomal secretion 4
                    negative regulation of regulated secretory pathway + 28
paths to the root