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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of carbohydrate metabolic process
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Accession:GO:0045912 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
Synonyms:exact_synonym: down regulation of carbohydrate metabolic process;   downregulation of carbohydrate metabolic process;   negative regulation of carbohydrate metabolism
 narrow_synonym: inhibition of carbohydrate metabolic process



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negative regulation of cellular glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 involved_in ISO (PMID:18004212) RGD PMID:18004212 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:18004212), (PMID:20610558) RGD PMID:18004212 PMID:20610558 NCBI chr 9:88,696,981...88,808,465 JBrowse link
negative regulation of glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cox11 cytochrome c oxidase copper chaperone COX11 acts_upstream_of_or_within ISO (MGI:3693040|PMID:17069463) RGD PMID:17069463 MGI:3693040 NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
JBrowse link
G Foxa2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) RGD PMID:11875061 MGI:5142372 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Gckr glucokinase regulator involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
PMID:14627435
MGI:2386670 (MGI:1354534|PMID:10713097)
PMID:21873635
(PMID:14627435), (PMID:23621087)
RGD PMID:10713097 PMID:14627435 PMID:23621087 PMID:14627435 PMID:21873635 MGI:1354534, RGD:1598592, RGD:13792537 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
G Midn midnolin acts_upstream_of_or_within IDA PMID:24187134 MGI PMID:24187134 RGD:8655525 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:24187134)
ParkinsonsUK-UCL
RGD
PMID:24187134 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520 JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3055866|PMID:11479628)
UniProt
RGD
PMID:11479628 GO_REF:0000024 MGI:3055866 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5317500|PMID:22275362)
RGD PMID:22275362 PMID:21873635 MGI:5317500, RGD:13792537 NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003
JBrowse link
G C1qtnf3 C1q and TNF related 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20952387)
(MGI:4868567|PMID:20952387)
RGD PMID:20952387 MGI:4868567 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G Clk2 CDC-like kinase 2 involved_in ISO (MGI:4429735|PMID:20074525) RGD PMID:20074525 MGI:4429735 NCBI chr 2:174,570,614...174,582,645 JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5914352|PMID:28790135), (MGI:6208175|PMID:29937374)
UniProt
RGD
PMID:28790135 PMID:29937374 GO_REF:0000024 MGI:5914352 MGI:6208175 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30193097) RGD PMID:30193097 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Erfe erythroferrone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:91,956,971...91,964,846
Ensembl chr 9:91,956,977...91,964,846
JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:152,166,716...152,175,327
Ensembl chr  X:152,165,535...152,175,362
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
JBrowse link
G Gck glucokinase involved_in ISO
IEA
ISS
(PMID:8878425)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8878425 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Il6 interleukin 6 IDA In liver RGD PMID:16308834 RGD:2306940 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8069456) RGD PMID:8069456 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:1856009 (MGI:5529403|PMID:24051374) RGD PMID:24051374 MGI:5529403 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Mst1 macrophage stimulating 1 involved_in ISO (PMID:19720831) RGD PMID:19720831 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (MGI:4946468|PMID:21135134) RGD PMID:21135134 MGI:4946468 NCBI chr 3:8,505,990...8,509,269
Ensembl chr 3:8,505,990...8,509,269
JBrowse link
G Pgp phosphoglycolate phosphatase involved_in IMP
ISO
PMID:26755581
(PMID:26755581)
RGD PMID:26755581 PMID:26755581 RGD:10679995 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3606826|PMID:16148943)
UniProt
RGD
PMID:16148943 GO_REF:0000024 MGI:3606826 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Soga1 suppressor of glucose, autophagy associated 1 involved_in ISO (MGI:4837302|PMID:20813965) RGD PMID:20813965 MGI:4837302 NCBI chr 3:145,669,102...145,741,578
Ensembl chr 3:145,675,443...145,740,871
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
negative regulation of glycogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO
IEA
(PMID:11289049)
GO_REF:0000107
RGD
Ensembl
PMID:11289049 GO_REF:0000107 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 IMP RGD PMID:8349040 RGD:1625425 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Grb10 growth factor receptor bound protein 10 involved_in IDA PMID:11223174 BHF-UCL PMID:11223174 RGD:8553640 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in IBA
ISO
PMID:21873635
(MGI:5294535|PMID:19250614)
(PMID:12556481)
RGD PMID:12556481 PMID:19250614 PMID:21873635 MGI:5294535, RGD:13792537 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
JBrowse link
G Insr insulin receptor IEP RGD PMID:26300412 RGD:11529553 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Pask PAS domain containing serine/threonine kinase involved_in ISO
IBA
(PMID:16275910)
PMID:21873635
RGD PMID:16275910 PMID:21873635 RGD:13792537 NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111
JBrowse link
negative regulation of glycogen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:2148638 (MGI:3027459|PMID:14581480) RGD PMID:14581480 MGI:3027459 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:381941) RGD PMID:381941 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) RGD PMID:23840896 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4440406|PMID:20176937)
Ensembl
RGD
PMID:20176937 GO_REF:0000107 MGI:4440406 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19881551), (PMID:25043030)
UniProt
Ensembl
RGD
PMID:19881551 PMID:25043030 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6478067|PMID:32460388)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:32460388 GO_REF:0000024 GO_REF:0000107 MGI:6478067 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) RGD PMID:19109424 MGI:4365327 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19955185)
Ensembl
RGD
PMID:19955185 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
(PMID:30451898)
GO_REF:0000024
RGD
UniProt
PMID:30451898 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) RGD PMID:19955185 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) RGD PMID:20141841 PMID:23217706 MGI:4881401 MGI:5619441 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5441121|PMID:22891351) RGD PMID:22891351 MGI:5441121 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4867601|PMID:20935145)
RGD PMID:20935145 PMID:21873635 MGI:4867601, RGD:13792537 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3820439|PMID:18698006)
Ensembl
RGD
PMID:18698006 GO_REF:0000107 MGI:3820439 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gckr glucokinase regulator IDA RGD PMID:14627435 RGD:1598592 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
negative regulation of hyaluronan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 involved_in ISO (PMID:23509262), (PMID:24251095) RGD PMID:23509262 PMID:24251095 NCBI chr 1:95,384,303...95,414,249
Ensembl chr 1:95,384,309...95,414,147
JBrowse link
G Cltc clathrin heavy chain involved_in ISO
IEA
ISS
(PMID:23509262), (PMID:24251095)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23509262 PMID:24251095 GO_REF:0000024 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856877 (MGI:5320806|PMID:22383528)
Ensembl
RGD
PMID:22383528 GO_REF:0000107 MGI:5320806 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:17324121)
GO_REF:0000024
RGD
UniProt
PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:228,409,883...229,638,794 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      negative regulation of metabolic process 3185
        negative regulation of carbohydrate metabolic process 60
          negative regulation of L-ascorbic acid biosynthetic process 0
          negative regulation of cell wall polysaccharide catabolic process + 0
          negative regulation of cellodextrin metabolic process + 0
          negative regulation of cellooligosaccharide metabolic process + 0
          negative regulation of cellotriose metabolic process + 0
          negative regulation of cellular carbohydrate metabolic process + 54
          negative regulation of cyclodextrin metabolic process + 0
          negative regulation of galactoglucomannan catabolic process 0
          negative regulation of galactomannan catabolic process 0
          negative regulation of glucomannan catabolic process 0
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          negative regulation of hyaluronan biosynthetic process 4
          negative regulation of maltoheptaose metabolic process 0
          negative regulation of raffinose biosynthetic process 0
          negative regulation of reductive pentose-phosphate cycle 0
Path 2
Term Annotations click to browse term
  biological_process 19504
    biological regulation 13513
      regulation of biological process 12770
        regulation of metabolic process 6748
          regulation of primary metabolic process 5709
            regulation of carbohydrate metabolic process 207
              negative regulation of carbohydrate metabolic process 60
                negative regulation of L-ascorbic acid biosynthetic process 0
                negative regulation of cell wall polysaccharide catabolic process + 0
                negative regulation of cellodextrin metabolic process + 0
                negative regulation of cellooligosaccharide metabolic process + 0
                negative regulation of cellotriose metabolic process + 0
                negative regulation of cellular carbohydrate metabolic process + 54
                negative regulation of cyclodextrin metabolic process + 0
                negative regulation of galactoglucomannan catabolic process 0
                negative regulation of galactomannan catabolic process 0
                negative regulation of glucomannan catabolic process 0
                negative regulation of glucose catabolic process to lactate via pyruvate 3
                negative regulation of hyaluronan biosynthetic process 4
                negative regulation of maltoheptaose metabolic process 0
                negative regulation of raffinose biosynthetic process 0
                negative regulation of reductive pentose-phosphate cycle 0
paths to the root