Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA recombination
go back to main search page
Accession:GO:0045910 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
Synonyms:exact_synonym: down regulation of DNA recombination;   downregulation of DNA recombination
 narrow_synonym: inhibition of DNA recombination


show annotations for term's descendants           Sort by:
 
negative regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:9671747) RGD PMID:9671747 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G H1f0 H1.0 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H1f1 H1.1 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011
JBrowse link
G H1f10 H1.10 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448
JBrowse link
G H1f2 H1.2 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,391,106...41,392,611 JBrowse link
G H1f4 H1.4 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H1f5 H1.5 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,726,189...42,726,857
Ensembl chr17:42,726,127...42,769,160
JBrowse link
G H1f6 H1.6 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,427,365...41,428,109
Ensembl chr17:41,427,323...41,428,119
JBrowse link
G H1f8 H1.8 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:148,993,133...148,998,254
Ensembl chr 4:148,993,133...148,998,254
JBrowse link
G H4f3 H1.3 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,528,576...41,554,586
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
JBrowse link
G Lig3 DNA ligase 3 acts_upstream_of_or_within ISO MGI:3629052 (MGI:3625660|PMID:16648486) RGD PMID:16648486 MGI:3625660 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:17715146)
MGI:1858055 (MGI:1351797|PMID:10545954), (MGI:74950|PMID:7628020)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:7628020 PMID:10545954 PMID:17715146 PMID:21873635 GO_REF:0000107 MGI:1351797 MGI:74950, RGD:13792537 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh3 mutS homolog 3 involved_in ISO (PMID:17715146) RGD PMID:17715146 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17715146)
MGI:2151803 (MGI:1351797|PMID:10545954)
PMID:21873635
RGD PMID:10545954 PMID:17715146 PMID:21873635 MGI:1351797, RGD:13792537 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3835812 (MGI:2448116|PMID:12509447) RGD PMID:12509447 MGI:2448116 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in IBA
ISO
PMID:21873635
(MGI:5645200|PMID:22579284)
RGD PMID:22579284 PMID:21873635 MGI:5645200, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558) RGD PMID:22704558 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link
negative regulation of DNA recombination at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pot1b protection of telomeres 1B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532
JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869)
UniProt
RGD
PMID:20339076 PMID:20622869 GO_REF:0000024 MGI:4440768 MGI:4839412 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064
JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in IBA
ISO
PMID:21873635
(MGI:6241455|PMID:30356214)
(PMID:30356214)
RGD PMID:30356214 PMID:21873635 MGI:6241455, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2156841 (MGI:5648586|PMID:25520194)
RGD PMID:25520194 PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:19736316)
(MGI:5566975|PMID:24108124)
RGD PMID:19736316 PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Helb DNA helicase B involved_in IBA
ISO
PMID:21873635
(MGI:5766842|PMID:26774285)
(PMID:26774285)
RGD PMID:26774285 PMID:21873635 MGI:5766842, RGD:13792537 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Klhl15 kelch-like family member 15 involved_in ISO (PMID:27561354) RGD PMID:27561354 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Parpbp PARP1 binding protein involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22153967)
UniProt
Ensembl
RGD
PMID:22153967 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:25642963)
(MGI:5621198|PMID:25642960)
RGD PMID:25642960 PMID:25642963 MGI:5621198 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked involved_in ISO
ISS
(PMID:28735897)
GO_REF:0000024
RGD
UniProt
PMID:28735897 GO_REF:0000024 NCBI chr  X:103,089,284...103,176,840
Ensembl chr  X:103,089,284...103,176,838
JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO MGI:2448558 (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23333306)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
RGD PMID:23306437 PMID:23333305 PMID:23333306 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Rmi2 RecQ mediated genome instability 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:4,829,333...4,837,264 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23345425)
(MGI:5476381|PMID:23333305), (MGI:5887194|PMID:20362325)
RGD PMID:20362325 PMID:23333305 PMID:23333306 PMID:23345425 MGI:5476381 MGI:5887194 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934
JBrowse link
G Thoc1 THO complex 1 involved_in ISO (MGI:5520039|PMID:22144908) RGD PMID:22144908 MGI:5520039 NCBI chr18:983,606...1,020,379
Ensembl chr18:983,824...1,019,114
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
negative regulation of mitotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in ISO UniProtKB:O88700 (MGI:5800654|PMID:27010503) RGD PMID:27010503 MGI:5800654 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within
involved_in
ISO MGI:1857708|MGI:2158669|MGI:2158670|MGI:3053044|MGI:3663359 (MGI:1312959|PMID:9808625), (MGI:1928200|PMID:11101838), (MGI:3655554|PMID:16914751), (MGI:3700903|PMID:17210642)
UniProtKB:A8VU90 (MGI:5800654|PMID:27010503)
RGD PMID:9808625 PMID:11101838 PMID:16914751 PMID:17210642 PMID:27010503 MGI:1312959 MGI:1928200 MGI:3655554 MGI:3700903 MGI:5800654 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858054 (MGI:3513725|PMID:15480418)
Ensembl
RGD
PMID:15480418 GO_REF:0000107 MGI:3513725 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA
(PMID:15507207)
(MGI:5883205|PMID:24120135)
PMID:21873635
RGD PMID:15507207 PMID:24120135 PMID:21873635 MGI:5883205, RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      negative regulation of metabolic process 3180
        negative regulation of macromolecule metabolic process 2956
          negative regulation of DNA metabolic process 133
            negative regulation of DNA recombination 47
              inactivation of recombination (HML) 0
              negative regulation of DNA recombination at centromere 0
              negative regulation of DNA recombination at telomere + 3
              negative regulation of double-strand break repair via homologous recombination + 18
              negative regulation of isotype switching + 6
              negative regulation of mitotic recombination + 4
              negative regulation of reciprocal meiotic recombination 0
              negative regulation of single-strand break repair via homologous recombination 0
              negative regulation of strand invasion 0
              negative regulation of transposition, DNA-mediated 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10721
        cellular aromatic compound metabolic process 5598
          nucleobase-containing compound metabolic process 5380
            nucleic acid metabolic process 4890
              DNA metabolic process 883
                DNA recombination 308
                  regulation of DNA recombination 111
                    negative regulation of DNA recombination 47
                      inactivation of recombination (HML) 0
                      negative regulation of DNA recombination at centromere 0
                      negative regulation of DNA recombination at telomere + 3
                      negative regulation of double-strand break repair via homologous recombination + 18
                      negative regulation of isotype switching + 6
                      negative regulation of mitotic recombination + 4
                      negative regulation of reciprocal meiotic recombination 0
                      negative regulation of single-strand break repair via homologous recombination 0
                      negative regulation of strand invasion 0
                      negative regulation of transposition, DNA-mediated 0
paths to the root