Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of proteolysis
go back to main search page
Accession:GO:0045862 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: positive regulation of peptidolysis;   up regulation of proteolysis;   upregulation of proteolysis
 narrow_synonym: activation of proteolysis;   stimulation of proteolysis


show annotations for term's descendants           Sort by:
positive regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:16885022) RGD PMID:16885022 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Capn3 calpain 3 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5306562|PMID:20139084)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20139084 GO_REF:0000024 GO_REF:0000107 MGI:5306562 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cd46 CD46 molecule IDA RGD PMID:15215199 RGD:2293559 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:15010453) RGD PMID:15010453 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:16973938 RGD:2289912 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fbxw11 F-box and WD repeat domain containing 11 involved_in ISO (PMID:16885022) RGD PMID:16885022 NCBI chr10:17,232,735...17,330,584
Ensembl chr10:17,227,181...17,330,571 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20798051)		 UniProt
RGD		 PMID:20798051 GO_REF:0000024 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Hdac2 histone deacetylase 2 involved_in ISO (PMID:19041327) RGD PMID:19041327 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IDA RGD PMID:9987077 RGD:10059370 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Ist1 IST1 factor associated with ESCRT-III involved_in ISO (PMID:20849418) RGD PMID:20849418 NCBI chr19:37,648,840...37,671,019
Ensembl chr19:37,648,095...37,670,956 		JBrowse link
G Oga O-GlcNAcase IMP Degradation of calmodulin-dependent protein kinase II and alpha fodrin (RGD: 621714). RGD PMID:17573462 RGD:2305953 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21285374)		 UniProt
Ensembl
RGD		 PMID:21285374 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO (PMID:16885022) RGD PMID:16885022 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Tbc1d10a TBC1 domain family, member 10a involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr14:79,051,822...79,083,603
Ensembl chr14:79,055,432...79,083,600 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 involved_in ISO (PMID:10206961) RGD PMID:10206961 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Asph aspartate-beta-hydroxylase involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IBA		 (PMID:18387192)
PMID:21873635		 RGD PMID:18387192 PMID:21873635 RGD:13792537 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Casp6 caspase 6 involved_in ISO (PMID:9922454) RGD PMID:9922454 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:10206961), (PMID:27882936) RGD PMID:10206961 PMID:27882936 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b involved_in ISO (PMID:12595532) RGD PMID:12595532 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605 		JBrowse link
G Cycs cytochrome c, somatic involved_in ISO (PMID:10206961) RGD PMID:10206961 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 involved_in IBA
ISO		 PMID:21873635
(PMID:18387192)		 RGD PMID:18387192 PMID:21873635 RGD:13792537 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Lgmn legumain involved_in ISO
IEA		 (PMID:18374643), (PMID:9821970)
GO_REF:0000107		 RGD
Ensembl		 PMID:9821970 PMID:18374643 GO_REF:0000107 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO (MGI:6453663|PMID:30248149) RGD PMID:30248149 MGI:6453663 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:10349840 RGD:9835366 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:5491128|PMID:23302887) RGD PMID:23302887 MGI:5491128 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tbc1d10a TBC1 domain family, member 10a involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr14:79,051,822...79,083,603
Ensembl chr14:79,055,432...79,083,600 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067042.3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:23,821,969...23,824,079 JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20628055) RGD PMID:20628055 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 involved_in ISO
ISS		 (PMID:17094969)
GO_REF:0000024		 RGD
UniProt		 PMID:17094969 GO_REF:0000024 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B involved_in ISO (PMID:20015864) RGD PMID:20015864 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:21827945)
MGI:1349414|MGI:1857868|MGI:1928692 (MGI:3575207|PMID:15776018), (MGI:3577148|PMID:15703386)		 RGD PMID:15703386 PMID:15776018 PMID:21827945 MGI:3575207 MGI:3577148 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in ISO
IEA		 (PMID:16725111)
GO_REF:0000107		 RGD
Ensembl		 PMID:16725111 GO_REF:0000107 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453294|PMID:19915011)		 UniProt
RGD		 PMID:19915011 GO_REF:0000024 MGI:4453294 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:2159364|MGI:99702 (MGI:2667259|PMID:12847083), (MGI:3575207|PMID:15776018), (MGI:3662939|PMID:16893972) RGD PMID:12847083 PMID:15776018 PMID:16893972 MGI:2667259 MGI:3575207 MGI:3662939 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:11350920), (PMID:11912183)
(MGI:5009404|PMID:16735463)
MGI:1097161|MGI:1857429|MGI:2158306 (MGI:2667259|PMID:12847083), (MGI:3041326|PMID:14561915), (MGI:3575207|PMID:15776018), (MGI:3692043|PMID:14502238)
GO_REF:0000024		 RGD
UniProt		 PMID:11350920 PMID:11912183 PMID:12847083 PMID:14502238 PMID:14561915 More... GO_REF:0000024 MGI:2667259 MGI:3041326 MGI:3575207 MGI:3692043 MGI:5009404 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11463392), (PMID:17024184)		 RGD PMID:11463392 PMID:17024184 PMID:21873635 RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000104
MGI:2158671 (MGI:2183141|PMID:12011074)		 UniProt
RGD		 PMID:12011074 PMID:21873635 GO_REF:0000104 MGI:2183141, RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(PMID:20673843)		 UniProt
RGD		 PMID:20673843 GO_REF:0000024 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp2 caspase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp4 caspase 4 TAS RGD PMID:11684090 RGD:632459 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2183141|PMID:12011074)
(PMID:16916640)
PMID:21873635		 RGD PMID:12011074 PMID:16916640 PMID:21873635 MGI:2183141, RGD:13792537 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17245429)
(MGI:1347587|PMID:10235259)
PMID:21873635		 RGD PMID:10235259 PMID:17245429 PMID:21873635 MGI:1347587, RGD:13792537 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Casp9 caspase 9 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2158755 (MGI:3575207|PMID:15776018)
(PMID:16916640)
PMID:21873635		 RGD PMID:15776018 PMID:16916640 PMID:21873635 MGI:3575207, RGD:13792537 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain involved_in ISO (PMID:10766752) RGD PMID:10766752 NCBI chr 9:83,875,958...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1889507 (MGI:3603971|PMID:16183742)
PMID:21873635		 RGD PMID:16183742 PMID:21873635 MGI:3603971, RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Dap death-associated protein involved_in ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein acts_upstream_of_or_within ISO (MGI:2183141|PMID:12011074), (MGI:3587135|PMID:16085184) RGD PMID:12011074 PMID:16085184 MGI:2183141 MGI:3587135 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO (PMID:17888903) RGD PMID:17888903 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:10411904) RGD PMID:10411904 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20978507)		 UniProt
RGD		 PMID:20978507 GO_REF:0000024 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (MGI:1858648|PMID:10882126) RGD PMID:10882126 MGI:1858648 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10692450)		 UniProt
Ensembl
RGD		 PMID:10692450 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in ISO (PMID:17898544) RGD PMID:17898544 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISO
ISS		 (PMID:15082785)
GO_REF:0000024		 RGD
UniProt		 PMID:15082785 GO_REF:0000024 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Faslg Fas ligand involved_in
acts_upstream_of_or_within		 ISO (PMID:18293083)
UniProtKB:P18406 (PMID:19364818)		 RGD PMID:18293083 PMID:19364818 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:11788820)		 RGD PMID:11788820 PMID:21873635 RGD:13792537 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IBA		 (PMID:19255499)
PMID:21873635		 RGD PMID:19255499 PMID:21873635 RGD:13792537 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:17823127) RGD PMID:17823127 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO (PMID:11788820) RGD PMID:11788820 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:5009182 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Khdc1 KH domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:23,812,442...23,814,932
Ensembl chr 9:23,813,746...23,814,813 		JBrowse link
G Khdc1b KH domain containing 1B acts_upstream_of_or_within ISO (MGI:2683352|PMID:14657025) RGD PMID:14657025 MGI:2683352 NCBI chr 9:23,821,993...23,827,647 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:28464033) RGD PMID:28464033 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 (PMID:16116473)
GO_REF:0000107		 RGD
Ensembl		 PMID:16116473 GO_REF:0000107 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Mtch1 mitochondrial carrier 1 involved_in ISO (PMID:12377771) RGD PMID:12377771 NCBI chr20:7,389,942...7,413,426
Ensembl chr20:7,389,949...7,413,426 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:2677658 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ngf nerve growth factor involved_in ISO UniProtKB:P08138 (PMID:11927634) RGD PMID:11927634 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor involved_in ISO
IEA		 (PMID:26268439)
GO_REF:0000107		 RGD
Ensembl		 PMID:26268439 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17486276)		 UniProt
RGD		 PMID:17486276 GO_REF:0000024 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO
IBA		 (PMID:15212762)
PMID:21873635		 RGD PMID:15212762 PMID:21873635 RGD:13792537 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 acts_upstream_of_or_within ISO MGI:3686871 (MGI:3697006|PMID:17008311) RGD PMID:17008311 MGI:3697006 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:10329646) RGD PMID:10329646 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Pdcd2 programmed cell death 2 involved_in ISO (PMID:20605493) RGD PMID:20605493 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437 		JBrowse link
G Pdcd6 programmed cell death 6 acts_upstream_of_or_within ISO (MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:2684521 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1336168 (MGI:3603971|PMID:16183742)
(PMID:17159900)		 RGD PMID:16183742 PMID:17159900 PMID:21873635 MGI:3603971, RGD:13792537 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO
IEA		 (MGI:5009174|PMID:14699081)
GO_REF:0000002		 RGD
InterPro		 PMID:14699081 GO_REF:0000002 MGI:5009174 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:1306978|PMID:9806545) RGD PMID:9806545 MGI:1306978 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3686870 (MGI:3697006|PMID:17008311)
PMID:21873635		 RGD PMID:17008311 PMID:21873635 MGI:3697006, RGD:13792537 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) RGD PMID:10082581 MGI:1333612 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO
IEA		 (PMID:18566128)
GO_REF:0000107		 RGD
Ensembl		 PMID:18566128 GO_REF:0000107 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:17057733) RGD PMID:17057733 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISO
ISS		 (PMID:19935772)
GO_REF:0000024		 RGD
UniProt		 PMID:19935772 GO_REF:0000024 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in ISO
IEA
ISS		 (PMID:19935772)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Senp1 SUMO specific peptidase 1 involved_in ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in ISO (PMID:18082289) RGD PMID:18082289 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 acts_upstream_of_or_within ISO (MGI:5508628|PMID:16858406) RGD PMID:16858406 MGI:5508628 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 acts_upstream_of IMP PMID:30120945 ARUK-UCL PMID:30120945 RGD:30309911 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:15107418) RGD PMID:15107418 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:21050448) RGD PMID:21050448 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (MGI:5447631|PMID:10692450) RGD PMID:10692450 MGI:5447631 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 ISO (PMID:16723520)
(MGI:3603971|PMID:16183742)		 RGD PMID:16183742 PMID:16723520 MGI:3603971 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf15 TNF superfamily member 15 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA		 GO_REF:0000107
(PMID:11911831)
PMID:21873635		 Ensembl
RGD		 PMID:11911831 PMID:11911831 PMID:21873635 GO_REF:0000107, RGD:634236, RGD:13792537 NCBI chr 5:77,140,099...77,156,142
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Vcp valosin-containing protein acts_upstream_of_or_within ISO (MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:2684521 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Xdh xanthine dehydrogenase involved_in ISO
IEA		 (PMID:18386220)
GO_REF:0000107		 RGD
Ensembl		 PMID:18386220 GO_REF:0000107 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 involved_in ISO (PMID:10206961), (PMID:9267021) RGD PMID:9267021 PMID:10206961 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:2159364 (MGI:2178486|PMID:11836241) RGD PMID:11836241 MGI:2178486 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857429 (MGI:1203837|PMID:9560217), (MGI:2178486|PMID:11836241)
(PMID:15214043)		 UniProt
RGD		 PMID:9560217 PMID:11836241 PMID:15214043 GO_REF:0000024 MGI:1203837 MGI:2178486 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568)		 UniProt
RGD		 PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:10206961) RGD PMID:10206961 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:24091666) RGD PMID:24091666 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731 		JBrowse link
G Cycs cytochrome c, somatic acts_upstream_of_or_within
involved_in		 ISO MGI:2154447|MGI:3581449 (MGI:1858667|PMID:10830166), (MGI:2681362|PMID:14623868), (MGI:3580764|PMID:15907471)
(PMID:10206961)		 RGD PMID:10206961 PMID:10830166 PMID:14623868 PMID:15907471 MGI:1858667 MGI:2681362 MGI:3580764 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2681362|PMID:14623868)
PMID:21873635		 RGD PMID:14623868 PMID:21873635 MGI:2681362, RGD:13792537 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G LOC100360940 diablo-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,744,994...141,746,345
Ensembl chr 5:141,744,961...141,746,356 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (MGI:1344924|PMID:10479688) RGD PMID:10479688 MGI:1344924 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:5009182 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Smad3 SMAD family member 3 IMP TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:18725990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18725990 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Hpse heparanase involved_in ISO (PMID:20634491) RGD PMID:20634491 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO UniProtKB:P05067:PRO_0000000093 (PMID:22406537) RGD PMID:22406537 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q15109 (PMID:22406537) RGD PMID:22406537 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Efna1 ephrin A1 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efna3 ephrin A3 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827|UniProtKB:P52797 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:24217950) RGD PMID:24217950 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5432454|PMID:22539346)
GO_REF:0000107		 Alzheimers_University_of_Toronto
RGD
Ensembl		 PMID:22539346 GO_REF:0000024 GO_REF:0000107 MGI:5432454 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO
IEA		 (PMID:24305806)
GO_REF:0000107
(MGI:6114922|PMID:24305806)		 RGD
Ensembl		 PMID:24305806 GO_REF:0000107 MGI:6114922 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
positive regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5907533|PMID:28453791)
(PMID:28453791)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28453791 GO_REF:0000024 GO_REF:0000107 MGI:5907533 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
positive regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO (PMID:19158676), (PMID:19158679)
(MGI:3839523|PMID:19158676), (MGI:5437433|PMID:19131592)		 RGD PMID:19131592 PMID:19158676 PMID:19158679 MGI:3839523 MGI:5437433 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4879048|PMID:21159964), (MGI:5448480|PMID:22761832)		 UniProt
RGD		 PMID:21159964 PMID:22761832 GO_REF:0000024 MGI:4879048 MGI:5448480 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IGI PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in IGI PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:19158676) RGD PMID:19158676 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Nek5 NIMA-related kinase 5 acts_upstream_of_or_within ISO (MGI:5500844|PMID:23727203) RGD PMID:23727203 MGI:5500844 NCBI chr16:69,895,414...69,938,668
Ensembl chr16:69,895,422...69,939,429 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:19158676) RGD PMID:19158676 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (MGI:5888801|PMID:28094437)
(PMID:28094437)		 RGD PMID:28094437 MGI:5888801 NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C involved_in ISO
IEA		 (PMID:15150278)
GO_REF:0000107		 RGD
Ensembl		 PMID:15150278 GO_REF:0000107 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15105833 RGD:2313858 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:21803450) RGD PMID:21803450 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18387645)		 Ensembl
RGD		 PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Arrb1 arrestin, beta 1 IMP RGD PMID:19171933 RGD:5510006 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
ISS		 (PMID:18402937)
GO_REF:0000024		 RGD
UniProt		 PMID:18402937 GO_REF:0000024 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within		 ISO (PMID:22267217)
(MGI:1355482|PMID:10753917)		 RGD PMID:10753917 PMID:22267217 MGI:1355482 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:2156498 (MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:3581932 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp1 caspase 1 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 IMP RGD PMID:17083921 RGD:2311464 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO UniProtKB:P48023 (MGI:3849354|PMID:19364818) RGD PMID:19364818 MGI:3849354 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 IMP caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Ctsd cathepsin D involved_in ISO
IEA		 (PMID:12107093)
GO_REF:0000107		 RGD
Ensembl		 PMID:12107093 GO_REF:0000107 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cycs cytochrome c, somatic involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cycs-ps9 cytochrome c, somatic, pseudogene 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:60,282,826...60,284,023
Ensembl chr18:60,282,810...60,284,019 		JBrowse link
G Cyct cytochrome c, testis involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:16132846) RGD PMID:16132846 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:16301996) RGD PMID:16301996 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO
ISS		 (PMID:10692450)
GO_REF:0000024		 RGD
UniProt		 PMID:10692450 GO_REF:0000024 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Fas Fas cell surface death receptor IMP RGD PMID:15519734 RGD:8662904 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:21183955) RGD PMID:21183955 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Foxl2 forkhead box L2 involved_in ISO (PMID:16153597) RGD PMID:16153597 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gramd4 GRAM domain containing 4 involved_in ISO
IBA		 (PMID:15565177)
PMID:21873635		 RGD PMID:15565177 PMID:21873635 RGD:13792537 NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:19800306) RGD PMID:19800306 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:11583623), (PMID:11604410), (PMID:11967569), (PMID:17297443) RGD PMID:11583623 PMID:11604410 PMID:11967569 PMID:17297443 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Il24 interleukin 24 acts_upstream_of_or_within ISO (MGI:3821693|PMID:18708357) RGD PMID:18708357 MGI:3821693 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G LOC690675 similar to Cytochrome c, somatic involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:35,324,038...35,324,419
Ensembl chr10:35,324,053...35,324,370 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:20674765) RGD PMID:20674765 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:14522843 RGD:2304239 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO (MGI:3037372|PMID:14688275) RGD PMID:14688275 MGI:3037372 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:19179467)
GO_REF:0000024		 RGD
UniProt		 PMID:19179467 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO UniProtKB:O43464 (PMID:17297443) RGD PMID:17297443 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20599703)		 UniProt
RGD		 PMID:20599703 GO_REF:0000024 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11821383), (PMID:15030775) RGD PMID:11821383 PMID:15030775 NCBI chr10:55,838,381...55,904,374
Ensembl chr10:55,843,001...55,912,774 		JBrowse link
G Nlrp2 NLR family pyrin domain containing 2 involved_in ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 1:69,515,505...69,554,689
Ensembl chr 1:69,515,505...69,554,454 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO
IBA		 (PMID:15030775)
PMID:21873635		 RGD PMID:15030775 PMID:21873635 RGD:13792537 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:10329646) RGD PMID:10329646 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:15150278) RGD PMID:15150278 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Pdcd5 programmed cell death 5 involved_in ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200 		JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO (PMID:16132846) RGD PMID:16132846 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081) RGD PMID:14699081 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F involved_in ISO
IBA
IDA		 (PMID:11559703)
PMID:21873635		 RGD PMID:11559703 PMID:21873635 PMID:11559703 RGD:13792537, RGD:8553939 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:18322138 RGD:8693423 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Pycard PYD and CARD domain containing involved_in IMP
ISO		 (PMID:15030775), (PMID:22267217) RGD PMID:15030775 PMID:22267217 PMID:19401709 RGD:5491174 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
ISS		 (PMID:20564196)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20564196 GO_REF:0000024 GO_REF:0000107 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G RGD1562558 similar to Cytochrome c, somatic involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:23,777,662...23,777,958
Ensembl chr15:23,777,662...23,777,958 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17425560 RGD:1642961 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:19047049) RGD PMID:19047049 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sox7 SRY-box transcription factor 7 involved_in ISO (PMID:19108950) RGD PMID:19108950 NCBI chr15:38,180,503...38,187,264
Ensembl chr15:38,180,503...38,187,264 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:11577081) RGD PMID:11577081 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:21459798), (PMID:21525171), (PMID:22266862) RGD PMID:21459798 PMID:21525171 PMID:22266862 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3043446 (MGI:3056865|PMID:15271982)		 RGD PMID:15271982 PMID:21873635 MGI:3056865, RGD:13792537 NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:20193664 RGD:11553917 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (MGI:3702339|PMID:17251350) RGD PMID:17251350 MGI:3702339 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor involved_in IBA
ISO		 PMID:21873635
(PMID:11096076)		 RGD PMID:11096076 PMID:21873635 RGD:13792537 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gsn gelsolin involved_in ISO (PMID:22952982) RGD PMID:22952982 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:11602612) RGD PMID:11602612 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Prr7 proline rich 7 (synaptic) involved_in ISO
ISS		 (PMID:21460222)
GO_REF:0000024		 RGD
UniProt		 PMID:21460222 GO_REF:0000024 NCBI chr17:9,164,375...9,173,669
Ensembl chr17:9,165,269...9,172,536 		JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor involved_in ISO
IEA		 (PMID:18676404)
GO_REF:0000107		 RGD
Ensembl		 PMID:18676404 GO_REF:0000107 NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790 		JBrowse link
G Tfap4 transcription factor AP-4 acts_upstream_of_or_within ISO (MGI:4456943|PMID:15944155) RGD PMID:15944155 MGI:4456943 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:12131680 RGD:14995454 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 IMP MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:12297508), (PMID:12763021)
(MGI:6478051|PMID:12522139)		 RGD PMID:12297508 PMID:12522139 PMID:12763021 MGI:6478051 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:12297508), (PMID:12763021) RGD PMID:12297508 PMID:12763021 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Ncstn nicastrin involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:12297508), (PMID:12763021) RGD PMID:12297508 PMID:12763021 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:18945965) RGD PMID:18945965 NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:12522139), (PMID:12660785), (PMID:12763021)
(MGI:6392999|PMID:12660785), (MGI:6478051|PMID:12522139)		 RGD PMID:12522139 PMID:12660785 PMID:12763021 MGI:6392999 MGI:6478051 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Psme1 proteasome activator subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890 		JBrowse link
G Psme1-ps1 proteasome activator subunit 1, pseudogene 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:50,174,233...50,175,012
Ensembl chr17:50,174,186...50,175,160 		JBrowse link
G Psme2 proteasome activator subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946 		JBrowse link
G Psme3 proteasome activator subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:20527027) RGD PMID:20527027 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO (MGI:3839034|PMID:19079247) RGD PMID:19079247 MGI:3839034 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:20666777) RGD PMID:20666777 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Cav1 caveolin 1 involved_in ISO (PMID:24089527) RGD PMID:24089527 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:18307982), (PMID:22045699) RGD PMID:18307982 PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO (PMID:23246001) RGD PMID:23246001 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18307982)		 Ensembl
UniProt
RGD		 PMID:18307982 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISO (PMID:17000876) RGD PMID:17000876 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISO
IEA		 (PMID:24424410)
GO_REF:0000107		 RGD
Ensembl		 PMID:24424410 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
ISS		 (PMID:27485036)
GO_REF:0000024		 RGD
UniProt		 PMID:27485036 GO_REF:0000024 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO
IBA		 (PMID:27485036)
PMID:21873635		 RGD PMID:27485036 PMID:21873635 RGD:13792537 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778 		JBrowse link
G Rnft2 ring finger protein, transmembrane 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:38,329,217...38,387,303
Ensembl chr12:38,329,269...38,387,290 		JBrowse link
G Tmem259 transmembrane protein 259 involved_in IBA
ISO		 PMID:21873635
(MGI:5648655|PMID:25977983)		 RGD PMID:25977983 PMID:21873635 MGI:5648655, RGD:13792537 NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932 		JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:4999711|PMID:19911006) RGD PMID:19911006 MGI:4999711 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
positive regulation of histone deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein involved_in ISO (PMID:24526689) UniProt PMID:24526689 NCBI chr12:42,859,026...42,887,041
Ensembl chr12:42,859,305...42,887,038 		JBrowse link
positive regulation of Lys63-specific deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vcp valosin-containing protein involved_in ISO (PMID:22970133) RGD PMID:22970133 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in IBA
ISO		 PMID:21873635
(MGI:3040545|PMID:14761956)
(PMID:15220135), (PMID:17548643)		 RGD PMID:14761956 PMID:15220135 PMID:17548643 PMID:21873635 MGI:3040545, RGD:13792537 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (MGI:1326990|PMID:9857183) RGD PMID:9857183 MGI:1326990 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA		 UniProtKB:P05067:PRO_0000000092 (PMID:15950758), (PMID:25015123)
GO_REF:0000107		 RGD
Ensembl		 PMID:15950758 PMID:25015123 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P02649 (PMID:25015123) RGD PMID:25015123 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5447609|PMID:17720976)
(PMID:17720976)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17720976 GO_REF:0000024 GO_REF:0000107 MGI:5447609 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Nrdc nardilysin convertase involved_in ISO
ISS
IEA		 (PMID:18355445)
(MGI:4414693|PMID:19935654)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18355445 PMID:19935654 GO_REF:0000024 GO_REF:0000107 MGI:4414693 NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595 		JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 involved_in ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within ISO (MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:5702499 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Sh3d19 SH3 domain containing 19 involved_in ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 2:171,356,244...171,516,042
Ensembl chr 2:171,356,251...171,515,561 		JBrowse link
G Snx33 sorting nexin 33 involved_in ISO (PMID:18353773), (PMID:18419754) RGD PMID:18353773 PMID:18419754 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538 		JBrowse link
G Snx9 sorting nexin 9 involved_in ISO (PMID:18353773) RGD PMID:18353773 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO
IBA		 (PMID:22480688)
PMID:21873635		 RGD PMID:22480688 PMID:21873635 RGD:13792537 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
positive regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Mbp myelin basic protein involved_in ISO (PMID:22524708) RGD PMID:22524708 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18591254) RGD PMID:18591254 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir92a1 microRNA 92a-1 involved_in ISO (PMID:23820254) RGD PMID:23820254 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 involved_in ISO (PMID:23820254) RGD PMID:23820254 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO RNAcentral:URS00003768C5_9606 (PMID:23820254) RGD PMID:23820254 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
positive regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Antxr1 ANTXR cell adhesion molecule 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5754386 (MGI:5662198|PMID:25572963)		 Ensembl
RGD		 PMID:25572963 GO_REF:0000107 MGI:5662198 NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232 		JBrowse link
G Cldn3 claudin 3 involved_in ISO (PMID:16103090) RGD PMID:16103090 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Cldn4 claudin 4 involved_in ISO (PMID:16103090) RGD PMID:16103090 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
positive regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cts7 cathepsin 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,388,299...3,424,664
Ensembl chr17:3,388,299...3,393,439 		JBrowse link
G Cts8 cathepsin 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,468,710...3,480,881
Ensembl chr17:3,468,710...3,480,881 		JBrowse link
G Ctsh cathepsin H involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
UniProtKB:P97821 (MGI:4838939|PMID:20435891)
(PMID:20435891)		 UniProt
Ensembl
RGD		 PMID:20435891 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4838939, RGD:13792537 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctsj cathepsin J involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,738,729...3,743,381
Ensembl chr17:3,738,729...3,743,377 		JBrowse link
G Ctsk cathepsin K involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctsm cathepsin M involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,236,848...3,242,265
Ensembl chr17:3,236,859...3,242,265 		JBrowse link
G Ctsq cathepsin Q involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,627,996...3,633,564
Ensembl chr17:3,629,082...3,633,428 		JBrowse link
G Ctsql2 cathepsin Q-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,698,973...3,704,787
Ensembl chr17:3,698,918...3,704,685 		JBrowse link
G Ctsr cathepsin R involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,522,365...3,531,128
Ensembl chr17:3,522,365...3,531,121 		JBrowse link
G Ctss cathepsin S involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G LOC100364523 Ctsq protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,681,700...3,687,099
Ensembl chr17:3,681,717...3,687,099 		JBrowse link
G MGC114246 similar to cathepsin R involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,561,144...3,566,649
Ensembl chr17:3,561,144...3,566,639 		JBrowse link
G Prss22 serine protease 22 involved_in ISO (PMID:15701722) RGD PMID:15701722 NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863 		JBrowse link
G Rcn3 reticulocalbin 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28939891)		 UniProt
Ensembl
RGD		 PMID:28939891 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725 		JBrowse link
G RGD1308751 similar to Cathepsin L precursor (Major excreted protein) (MEP) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,903,602...3,907,088
Ensembl chr17:3,903,602...3,906,568 		JBrowse link
G RGD1564657 similar to cathepsin 1 precursor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,306,668...3,311,964
Ensembl chr17:3,307,748...3,311,679 		JBrowse link
G RGD1564827 similar to cathepsin M involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,752,079...3,756,082
Ensembl chr17:3,752,000...3,760,046 		JBrowse link
G Testin testin gene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385 		JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:9836589) RGD PMID:9836589 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Clec3b C-type lectin domain family 3, member B involved_in ISS
ISO		 GO_REF:0000024
(MGI:5447625|PMID:12694198)		 UniProt
RGD		 PMID:12694198 GO_REF:0000024 MGI:5447625 NCBI chr 8:122,810,091...122,817,039
Ensembl chr 8:122,810,149...122,815,835 		JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:12666133) RGD PMID:12666133 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:89876)
GO_REF:0000107		 RGD
Ensembl		 PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Hpn hepsin involved_in ISS
ISO		 GO_REF:0000024
(PMID:16908524)		 UniProt
RGD		 PMID:16908524 GO_REF:0000024 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300 		JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:4437195|PMID:19897580)		 RGD PMID:19897580 PMID:21873635 MGI:4437195, RGD:13792537 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:11027681 RGD:67924 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G S100a10 S100 calcium binding protein A10 involved_in ISO (PMID:9836589) RGD PMID:9836589 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
ISS		 (PMID:20080667)
GO_REF:0000024		 RGD
UniProt		 PMID:20080667 GO_REF:0000024 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:19416853)		 RGD PMID:19416853 PMID:21873635 RGD:13792537 NCBI chr18:27,309,711...27,319,106
Ensembl chr18:27,309,718...27,319,032 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5770038|PMID:24709664)		 UniProt
RGD		 PMID:24709664 GO_REF:0000024 MGI:5770038 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:22180649) RGD PMID:22180649 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO		 GO_REF:0000024
(PMID:16300740)		 UniProt
RGD		 PMID:16300740 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Osbpl7 oxysterol binding protein-like 7 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Rnf40 ring finger protein 40 IDA RGD PMID:12121982 RGD:633892 NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in ISO (PMID:21603654) RGD PMID:21603654 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6150565|PMID:29518356) RGD PMID:29518356 MGI:6150565 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) RGD PMID:21317886 MGI:4946566 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO (MGI:3589701|PMID:15937334)
(PMID:23512198)		 RGD PMID:15937334 PMID:23512198 MGI:3589701 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2446434|MGI:3587769|MGI:3691571 (MGI:5465208|PMID:23152632) RGD PMID:23152632 MGI:5465208 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Aurka aurora kinase A acts_upstream_of_or_within ISO (MGI:3697244|PMID:17060449) RGD PMID:17060449 MGI:3697244 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3628833|PMID:16601693)
PMID:21873635		 RGD PMID:16601693 PMID:21873635 MGI:3628833, RGD:13792537 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bag2 BAG cochaperone 2 NOT|involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO UniProtKB:Q99496 (PMID:22302990) RGD PMID:22302990 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:25974097) RGD PMID:25974097 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (MGI:5310666|PMID:22285184) RGD PMID:22285184 MGI:5310666 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Clu clusterin involved_in ISO
IBA
IEA
ISS		 (PMID:20068069)
PMID:21873635
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20068069 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cop1 COP1, E3 ubiquitin ligase involved_in ISO (PMID:19805145) RGD PMID:19805145 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISO (PMID:11955436), (PMID:19364825) RGD PMID:11955436 PMID:19364825 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:3849793|PMID:19414593)		 UniProt
RGD		 PMID:19414593 PMID:21873635 GO_REF:0000024 MGI:3849793, RGD:13792537 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO
IBA		 (MGI:3849793|PMID:19414593)
PMID:21873635		 RGD PMID:19414593 PMID:21873635 MGI:3849793, RGD:13792537 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12805222)		 Ensembl
RGD		 PMID:12805222 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dda1 DET1 and DDB1 associated 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IBA
ISO		 PMID:21873635
UniProtKB:Q8NHY2 (PMID:14739464)		 RGD PMID:14739464 PMID:21873635 RGD:13792537 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IBA
ISO		 PMID:21873635
(PMID:15936278)		 RGD PMID:15936278 PMID:21873635 RGD:13792537 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Fbxo22 F-box protein 22 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3840749|PMID:19319192)
PMID:21873635		 RGD PMID:19319192 PMID:21873635 MGI:3840749, RGD:13792537 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:25684205)		 UniProt
RGD		 PMID:25684205 GO_REF:0000024 NCBI chr10:54,714,834...54,717,769
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Gba glucosylceramidase beta involved_in ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2387010 (MGI:3695876|PMID:17189825) RGD PMID:17189825 MGI:3695876 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:25897075) RGD PMID:25897075 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1924375|MGI:3039600 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:22660580), (PMID:25897075)
GO_REF:0000107		 RGD
Ensembl		 PMID:19364825 PMID:22660580 PMID:25897075 GO_REF:0000107 MGI:5437589 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 involved_in ISO (PMID:16831871) RGD PMID:16831871 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861437|MGI:3039600 (MGI:5437589|PMID:22660580)		 Ensembl
RGD		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) RGD PMID:25940086 MGI:5700633 NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (MGI:4454597|PMID:20457918) RGD PMID:20457918 MGI:4454597 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 RGD PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 involved_in ISO (PMID:16707496) RGD PMID:16707496 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO
ISS		 (PMID:27588481)
GO_REF:0000024		 RGD
UniProt		 PMID:27588481 GO_REF:0000024 NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 involved_in ISO (MGI:5487503|PMID:22406621) RGD PMID:22406621 MGI:5487503 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO
ISS
IEA		 (PMID:19473992)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19473992 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:17030191)
GO_REF:0000107		 RGD
Ensembl		 PMID:17030191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IBA
ISO		 PMID:21873635
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 PMID:21873635 MGI:5543313, RGD:13792537 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
ISS		 (PMID:16023600)
GO_REF:0000024		 RGD
UniProt		 PMID:16023600 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19785988)		 UniProt
RGD		 PMID:19785988 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:26296656) RGD PMID:26296656 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO UniProtKB:Q7L5Y6 (PMID:14739464) RGD PMID:14739464 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Rnf14 ring finger protein 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685 		JBrowse link
G Rnf144a ring finger protein 144A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Rnf144b ring finger protein 144B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)		 RGD PMID:18363970 PMID:23926250 PMID:21873635 MGI:3819024 MGI:5505713, RGD:13792537 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222 		JBrowse link
G Rnf19b ring finger protein 19B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,406,085...141,431,380
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf217 ring finger protein 217 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:26,016,668...26,108,736
Ensembl chr 1:26,015,728...26,108,736 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP
IBA
ISO		 PMID:22128169
PMID:21873635
(PMID:22128169)		 RGD PMID:22128169 PMID:22128169 PMID:21873635 RGD:13673844, RGD:13792537 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5574427|PMID:24681946)		 UniProt
RGD		 PMID:24681946 GO_REF:0000024 MGI:5574427 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA		 (PMID:11278251)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278251 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:11146632) RGD PMID:11146632 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) RGD PMID:15053879 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in IBA
ISO		 PMID:21873635
(MGI:4457446|PMID:20410507)		 RGD PMID:20410507 PMID:21873635 MGI:4457446, RGD:13792537 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib2 tribbles pseudokinase 2 involved_in ISO (MGI:4457446|PMID:20410507) RGD PMID:20410507 MGI:4457446 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:19098288) RGD PMID:19098288 NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:9452483) RGD PMID:9452483 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Zer1 zyg-11 related, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 3:13,369,688...13,397,524
Ensembl chr 3:13,369,688...13,397,420 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO MGI:3664591 (MGI:3663213|PMID:16973439) RGD PMID:16973439 MGI:3663213 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677 		JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20889502)		 UniProt
RGD		 PMID:20889502 GO_REF:0000024 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
ISS		 (PMID:24681946)
GO_REF:0000024		 RGD
UniProt		 PMID:24681946 GO_REF:0000024 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
positive regulation of protein deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:25861989) RGD PMID:25861989 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:16684768) RGD PMID:16684768 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO (PMID:31253762) UniProt PMID:31253762 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(PMID:25861989)		 UniProt
RGD		 PMID:25861989 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
positive regulation of protein K63-linked deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) RGD PMID:27824081 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:22970133) RGD PMID:22970133 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl8 angiopoietin-like 8 acts_upstream_of_or_within ISO (PMID:23150577) RGD PMID:23150577 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490 		JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (MGI:5427546|PMID:22472438) RGD PMID:22472438 MGI:5427546 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868 		JBrowse link
G Bag2 BAG cochaperone 2 involved_in ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO (PMID:24552833) RGD PMID:24552833 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400 		JBrowse link
G Cntn2 contactin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3835738|PMID:18278038)		 Ensembl
RGD		 PMID:18278038 GO_REF:0000107 MGI:3835738 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:98397 (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (MGI:4367921|PMID:19877275) RGD PMID:19877275 MGI:4367921 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
G Mbl2 mannose binding lectin 2 IDA Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mmp14 matrix metallopeptidase 14 IMP RGD PMID:14668206 RGD:1582606 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15064403) RGD PMID:15064403 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5437551|PMID:22795130)		 UniProt
RGD		 PMID:22795130 GO_REF:0000024 MGI:5437551 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3607023|PMID:16227578)		 Ensembl
RGD		 PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:105100 (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A IMP RGD PMID:9756630 RGD:13463485 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 IMP RGD PMID:9756630 RGD:13463485 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379 		JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897488|PMID:28366643)		 UniProt
RGD		 PMID:28366643 GO_REF:0000024 MGI:5897488 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274 		JBrowse link
G Tnp2 transition protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5897488|PMID:28366643)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28366643 GO_REF:0000024 GO_REF:0000107 MGI:5897488 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538 		JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (MGI:5619440|PMID:23325791) RGD PMID:23325791 MGI:5619440 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
IEA		 (MGI:5619440|PMID:23325791)
GO_REF:0000107		 RGD
Ensembl		 PMID:23325791 GO_REF:0000107 MGI:5619440 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Ctsc cathepsin C involved_in IDA PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:21700325)
(MGI:5141165|PMID:21700325)		 RGD PMID:21700325 MGI:5141165 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) RGD PMID:22949502 MGI:5444793 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Rgn regucalcin IDA RGD PMID:1513338 RGD:9590188 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
positive regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Semg1 semenogelin 1 involved_in ISO (PMID:15563730) RGD PMID:15563730 NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882 		JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw8 F-box and WD repeat domain containing 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr12:38,426,443...38,518,712
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27457971) RGD PMID:27457971 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agbl4 AGBL carboxypeptidase 4 acts_upstream_of_or_within ISO MGI:5788002 (MGI:6149282|PMID:29593216) RGD PMID:29593216 MGI:6149282 NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within ISO MGI:1857523 (MGI:6149282|PMID:29593216) RGD PMID:29593216 MGI:6149282 NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869 		JBrowse link
G Axin1 axin 1 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:10228155
(MGI:3628833|PMID:16601693)		 RGD PMID:16601693 PMID:10228155 MGI:3628833, RGD:8553327 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Ccdc22 coiled-coil domain containing 22 involved_in IBA
ISO		 PMID:21873635
(PMID:23563313)		 RGD PMID:23563313 PMID:21873635 RGD:13792537 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 NOT|involved_in ISS
ISO		 GO_REF:0000024
(PMID:16173922)		 UniProt
RGD		 PMID:16173922 GO_REF:0000024 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Clu clusterin involved_in ISS
ISO		 GO_REF:0000024
(PMID:20068069)		 UniProt
RGD		 PMID:20068069 GO_REF:0000024 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Disc1 DISC1 scaffold protein acts_upstream_of_or_within ISO (MGI:4837265|PMID:20880836) RGD PMID:20880836 MGI:4837265 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Egf epidermal growth factor involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Fbxo22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) RGD PMID:19319192 MGI:3840749 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO
ISS		 (PMID:20208556), (PMID:27238018)
(MGI:6282935|PMID:27238018)
GO_REF:0000024		 RGD
UniProt		 PMID:20208556 PMID:27238018 GO_REF:0000024 MGI:6282935 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G L3mbtl3 L3MBTL histone methyl-lysine binding protein 3 involved_in ISO (PMID:29691401) RGD PMID:29691401 NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870), (MGI:6478861|PMID:24638062) RGD PMID:18619870 PMID:24638062 MGI:3803048 MGI:6478861 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306293|PMID:18206965)		 UniProt
RGD		 PMID:18206965 GO_REF:0000024 MGI:5306293 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453113|PMID:19880522)		 UniProt
RGD		 PMID:19880522 GO_REF:0000024 MGI:4453113 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rnf139 ring finger protein 139 involved_in ISO (PMID:25239945) RGD PMID:25239945 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:21454619) RGD PMID:21454619 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Sumo3 small ubiquitin-like modifier 3 acts_upstream_of_or_within ISO (MGI:3813414|PMID:18644859) RGD PMID:18644859 MGI:3813414 NCBI chr20:11,010,140...11,020,850
Ensembl chr20:11,007,148...11,020,877
Ensembl chr20:11,007,148...11,020,877 		JBrowse link
G Trim67 tripartite motif-containing 67 acts_upstream_of_or_within ISO (MGI:5427306|PMID:22337885) RGD PMID:22337885 MGI:5427306 NCBI chr19:52,763,991...52,805,906
Ensembl chr19:52,764,387...52,800,422 		JBrowse link
G Vcp valosin-containing protein IMP RGD PMID:16103111 RGD:1599730 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
positive regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tank TRAF family member-associated NFKB activator involved_in ISO (PMID:25861989) RGD PMID:25861989 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      primary metabolic process 10827
        protein metabolic process 5955
          proteolysis 1876
            positive regulation of proteolysis 397
              positive regulation of membrane protein ectodomain proteolysis 16
              positive regulation of peptidase activity + 209
              positive regulation of protein desumoylation 0
              positive regulation of protein deubiquitination + 7
              positive regulation of protein processing + 31
              positive regulation of proteolysis involved in protein catabolic process + 135
Path 2
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      organic substance metabolic process 11599
        macromolecule metabolic process 9961
          protein metabolic process 5955
            proteolysis 1876
              regulation of proteolysis 753
                positive regulation of proteolysis 397
                  positive regulation of membrane protein ectodomain proteolysis 16
                  positive regulation of peptidase activity + 209
                  positive regulation of protein desumoylation 0
                  positive regulation of protein deubiquitination + 7
                  positive regulation of protein processing + 31
                  positive regulation of proteolysis involved in protein catabolic process + 135
paths to the root