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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteolysis
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Accession:GO:0045861 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: down regulation of proteolysis;   downregulation of proteolysis;   negative regulation of peptidolysis
 narrow_synonym: inhibition of proteolysis



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negative regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA
(PMID:18387192)
GO_REF:0000107
RGD
Ensembl
PMID:18387192 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Andpro androgen regulated protein involved_in ISO (PMID:3488317) RGD PMID:3488317 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:18056262)
UniProt
RGD
PMID:18056262 GO_REF:0000024 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in ISO
IEA
(PMID:24548080)
GO_REF:0000107
RGD
Ensembl
PMID:24548080 GO_REF:0000107 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:1933976 (PMID:10527801) RGD PMID:10527801 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cst3 cystatin C involved_in ISO (PMID:3488317) RGD PMID:3488317 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Csta cystatin A involved_in ISO (PMID:3488317) RGD PMID:3488317 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Cstb cystatin B involved_in ISO (PMID:3488317) RGD PMID:3488317 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO
GO_REF:0000107
(PMID:1695900)
Ensembl
RGD
PMID:1695900 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO (PMID:18356165) RGD PMID:18356165 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Ide insulin degrading enzyme IDA inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:3553851) RGD PMID:3553851 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Kng1 kininogen 1 involved_in ISO (PMID:3488317) RGD PMID:3488317 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:3356189 RGD:1600550 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Mir126a microRNA 126a acts_upstream_of ISO RNAcentral:URS00001D69F6_9606|RNAcentral:URS00001F1DA8_9606 (PMID:23437250) RGD PMID:23437250 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:18806227)
Ensembl
RGD
PMID:18806227 GO_REF:0000107 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:18806227)
GO_REF:0000107
RGD
Ensembl
PMID:18806227 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IMP RGD PMID:15161606 RGD:1625251 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plat plasminogen activator, tissue type involved_in ISO
IEA
(PMID:1695900)
GO_REF:0000107
RGD
Ensembl
PMID:1695900 GO_REF:0000107 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2137533 (PMID:16364285) RGD PMID:16364285 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Serpina5 serpin family A member 5 IDA RGD PMID:16088033 RGD:1580291 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407
JBrowse link
G Serpinb10 serpin family B member 10 IDA RGD PMID:11986314 RGD:634009 NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182
JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:12975381) RGD PMID:12975381 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IDA
(PMID:17379830), (PMID:3997857) RGD PMID:3997857 PMID:17379830 PMID:17379830 RGD:8553298 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 acts_upstream_of_or_within ISO (PMID:15466487) RGD PMID:15466487 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185
JBrowse link
G Spink9 serine peptidase inhibitor, Kazal type 9 acts_upstream_of_or_within ISO (PMID:16930550) RGD PMID:16930550 NCBI chr18:36,427,043...36,430,271
Ensembl chr18:36,426,989...36,430,271
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IMP RGD PMID:17532789 RGD:2290425 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IMP RGD PMID:17532789 RGD:2290425 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tm4sf20 transmembrane 4 L six family member 20 involved_in ISO (PMID:25310401), (PMID:27499293) RGD PMID:25310401 PMID:27499293 NCBI chr 9:84,038,715...84,052,615
Ensembl chr 9:84,038,715...84,052,615
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23277542)
Ensembl
RGD
PMID:23277542 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ubxn2a UBX domain protein 2A involved_in ISO (PMID:26634371) RGD PMID:26634371 NCBI chr 6:27,884,364...27,912,767
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649
JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin involved_in ISO (PMID:2407243) RGD PMID:2407243 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cst7 cystatin F acts_upstream_of_or_within ISO MGI:5910746 (PMID:28251676) RGD PMID:28251676 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:16639714 UniProt PMID:16639714 RGD:10047164 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO (PMID:27179792) RGD PMID:27179792 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (PMID:16641999) RGD PMID:16641999 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp1 aquaporin 1 involved_in ISO (PMID:21215257) RGD PMID:21215257 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 involved_in ISO (PMID:12754298) RGD PMID:12754298 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Bcl2l12 Bcl2 like 12 involved_in ISO (PMID:22262180) RGD PMID:22262180 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISO
ISS
(PMID:12773388), (PMID:9859993)
GO_REF:0000024
RGD
UniProt
PMID:9859993 PMID:12773388 GO_REF:0000024 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 involved_in ISO (PMID:21980415) RGD PMID:21980415 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Cd44 CD44 molecule involved_in ISO (PMID:19047049) RGD PMID:19047049 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Csn2 casein beta involved_in ISO (PMID:12788072) RGD PMID:12788072 NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO
ISS
(PMID:16193064)
GO_REF:0000024
RGD
UniProt
PMID:16193064 GO_REF:0000024 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:10411904) RGD PMID:10411904 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 involved_in ISO (PMID:11896048) RGD PMID:11896048 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO
ISS
(PMID:20435919)
GO_REF:0000024
RGD
UniProt
PMID:20435919 GO_REF:0000024 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Fabp1 fatty acid binding protein 1 involved_in ISO (PMID:16175609) RGD PMID:16175609 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS
(PMID:16723520)
GO_REF:0000024
RGD
UniProt
PMID:16723520 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049
JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in ISO (PMID:12773388) RGD PMID:12773388 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:12788072) RGD PMID:12788072 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 involved_in ISO (PMID:11896143) RGD PMID:11896143 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IDA
(PMID:15509781)
PMID:19001025
RGD PMID:15509781 PMID:19001025 RGD:8553292 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:21555521) RGD PMID:21555521 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pax2 paired box 2 involved_in ISO
ISS
(PMID:10980123), (PMID:17357786)
GO_REF:0000024
RGD
UniProt
PMID:10980123 PMID:17357786 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947) RGD PMID:20870947 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712
JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:21078300) RGD PMID:21078300 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:15069192)
GO_REF:0000024
RGD
UniProt
PMID:15069192 GO_REF:0000024 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rnf34 ring finger protein 34 involved_in ISO
ISS
(PMID:15069192)
GO_REF:0000024
RGD
UniProt
PMID:15069192 GO_REF:0000024 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18653767) RGD PMID:18653767 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Usp47 ubiquitin specific peptidase 47 involved_in ISO (PMID:19966869) RGD PMID:19966869 NCBI chr 1:166,152,104...166,235,312
Ensembl chr 1:166,152,199...166,235,312
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:18386220) RGD PMID:18386220 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11583623) RGD PMID:11583623 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IDA RGD PMID:19240864 RGD:7411612 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:18387192) RGD PMID:18387192 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISO (PMID:20299451) RGD PMID:20299451 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
JBrowse link
G Fetub fetuin B involved_in ISS
ISO
GO_REF:0000024
(PMID:23562279)
UniProt
RGD
PMID:23562279 GO_REF:0000024 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) RGD PMID:22832495 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in IC PMID:8626514 BHF-UCL PMID:8626514 RGD:8554276 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in IC PMID:8626514 BHF-UCL PMID:8626514 RGD:8554276 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Mir339 microRNA 339 involved_in ISO (PMID:24352696) RGD PMID:24352696 NCBI chr12:15,277,546...15,277,641
Ensembl chr12:15,277,546...15,277,641
JBrowse link
G Renbp renin binding protein IDA RGD PMID:11926999 RGD:727355 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516
JBrowse link
G Serpinb13 serpin family B member 13 involved_in ISO (PMID:12504904) RGD PMID:12504904 NCBI chr13:23,118,582...23,150,352
Ensembl chr13:23,118,584...23,150,760
JBrowse link
G Serpinb1a serpin family B member 1A involved_in ISO (PMID:30692621) RGD PMID:30692621 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:21383048) RGD PMID:21383048 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Serpinb6a serpin family B member 6A involved_in ISO (PMID:17761692) RGD PMID:17761692 NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Serpinb8 serpin family B member 8 involved_in ISO (PMID:8530382) RGD PMID:8530382 NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Serpine1 serpin family E member 1 involved_in IDA
ISO
IC
(PMID:1695900)
PMID:8626514
RGD PMID:1695900 PMID:10717410 PMID:8626514 RGD:8547889, RGD:8554276 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 involved_in ISO (PMID:14511383) RGD PMID:14511383 NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935
JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 involved_in ISO (PMID:11751414) RGD PMID:11751414 NCBI chr16:26,382,895...26,815,943
Ensembl chr16:26,383,383...26,815,205
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:3903517)
UniProt
RGD
PMID:3903517 GO_REF:0000024 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Vtn vitronectin involved_in ISO (PMID:1695900) RGD PMID:1695900 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp11 aquaporin 11 involved_in ISS
ISO
GO_REF:0000024
(PMID:18606867)
UniProt
RGD
PMID:18606867 GO_REF:0000024 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:23129660)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23129660 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Svip small VCP interacting protein involved_in IDA
IBA
ISO
IEA
PMID:17000876
GO_REF:0000033
(PMID:17872946)
GO_REF:0000107
GO_Central
RGD
Ensembl
PMID:17872946 PMID:17000876 GO_REF:0000033 GO_REF:0000107, RGD:10047192 NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116
JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520
JBrowse link
G Ubxn2a UBX domain protein 2A involved_in ISS
ISO
GO_REF:0000024
(PMID:26265139)
UniProt
RGD
PMID:26265139 GO_REF:0000024 NCBI chr 6:27,884,364...27,912,767
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649
JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO
IBA
(PMID:19135427)
GO_REF:0000033
RGD
GO_Central
PMID:19135427 GO_REF:0000033 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
JBrowse link
G Usp25 ubiquitin specific peptidase 25 involved_in ISO (PMID:22590560) RGD PMID:22590560 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO
ISS
(PMID:18383040)
GO_REF:0000024
RGD
UniProt
PMID:18383040 GO_REF:0000024 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO (PMID:26651291) RGD PMID:26651291 NCBI chr 2:191,947,322...192,012,996
Ensembl chr 2:191,949,819...192,012,579
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 involved_in ISO (PMID:12207026) RGD PMID:12207026 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISO
IBA
(PMID:12714508)
GO_REF:0000033
RGD
GO_Central
PMID:12714508 GO_REF:0000033 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO
IBA
IEA
(PMID:18383040)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:18383040 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir152 microRNA 152 involved_in ISO (PMID:24813629) RGD PMID:24813629 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs involved_in ISO (PMID:18194466)
(PMID:24812324)
RGD PMID:18194466 PMID:24812324 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO (PMID:24812324) RGD PMID:24812324 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:28358369) RGD PMID:28358369 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:9573338) RGD PMID:9573338 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 involved_in ISO (PMID:9573338) RGD PMID:9573338 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin acts_upstream_of_or_within ISO MGI:88264 (PMID:21849499) RGD PMID:21849499 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cst3 cystatin C involved_in ISO (PMID:18256700), (PMID:6203523), (PMID:7890620) RGD PMID:6203523 PMID:7890620 PMID:18256700 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cst7 cystatin F involved_in ISO (PMID:15752368), (PMID:18256700), (PMID:22365146)
(PMID:18256700)
RGD PMID:15752368 PMID:18256700 PMID:22365146 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Csta cystatin A involved_in ISO (PMID:6203523) RGD PMID:6203523 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Cstb cystatin B involved_in ISO (PMID:6203523) RGD PMID:6203523 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Cyss cystatin S IDA Papain
Ficin
RGD PMID:7575236 PMID:3263967 RGD:2306757, RGD:1299643 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610
JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16512877)
UniProt
RGD
PMID:16512877 GO_REF:0000024 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
JBrowse link
G Eppin epididymal peptidase inhibitor involved_in ISS
ISO
GO_REF:0000024
(PMID:18331357)
UniProt
RGD
PMID:18331357 GO_REF:0000024 NCBI chr 3:153,312,396...153,319,310
Ensembl chr 3:153,312,396...153,319,310
JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:12949073) RGD PMID:12949073 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:12949073) RGD PMID:12949073 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (PMID:15509762), (PMID:18398001) RGD PMID:15509762 PMID:18398001 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Smr3b submaxillary gland androgen regulated protein 3B involved_in IDA PMID:12835417 UniProt PMID:12835417 RGD:8553855 NCBI chr14:19,783,815...19,788,557
Ensembl chr14:19,783,816...19,788,492
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 acts_upstream_of_or_within ISO (PMID:3428272) RGD PMID:3428272 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Ctsz cathepsin Z involved_in ISO
IEA
(PMID:19433310)
GO_REF:0000107
RGD
Ensembl
PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:19855083)
GO_REF:0000033
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
GO_Central
PMID:8508955 PMID:18835034 PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase involved_in ISO (PMID:8175643) RGD PMID:8175643 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G F8a1 coagulation factor VIII-associated 1 involved_in ISO
ISS
(PMID:27815841)
GO_REF:0000024
RGD
UniProt
PMID:27815841 GO_REF:0000024 NCBI chr  X:150,957,357...150,958,871
Ensembl chr  X:150,916,679...150,960,168
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
Ensembl chr 8:39,910,534...39,924,628
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in IMP
ISO
PMID:17517623
(PMID:17517623)
RGD PMID:17517623 PMID:17517623 RGD:13514081 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 involved_in ISO (PMID:25681212) RGD PMID:25681212 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
JBrowse link
G LOC134484027 40-kDa huntingtin-associated protein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:29295817)
UniProt
Ensembl
RGD
PMID:29295817 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168
JBrowse link
G Ophn1 oligophrenin 1 involved_in IBA
ISO
GO_REF:0000033
(PMID:21874017)
GO_Central
RGD
PMID:21874017 GO_REF:0000033 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633
JBrowse link
G Prkcg protein kinase C, gamma involved_in ISS
ISO
GO_REF:0000024
(PMID:23185022)
UniProt
RGD
PMID:23185022 GO_REF:0000024 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Psme3ip1 proteasome activator subunit 3 interacting protein 1 involved_in ISO (PMID:29934401) RGD PMID:29934401 NCBI chr19:10,401,400...10,430,059
Ensembl chr19:10,401,532...10,429,987
JBrowse link
G Psmf1 proteasome inhibitor subunit 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:10764772)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:10764772 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO MGI:2176228|MGI:5758867 (PMID:25683716) RGD PMID:25683716 NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237
JBrowse link
G Usp19 ubiquitin specific peptidase 19 involved_in ISO (PMID:25088257) RGD PMID:25088257 NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741
JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:18678708)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18678708 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Camlg calcium modulating ligand involved_in ISO UniProtKB:Q9H9V4 (PMID:20553626) RGD PMID:20553626 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23398316) RGD PMID:23398316 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292) RGD PMID:28031292 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292) RGD PMID:28031292 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO
IEA
(PMID:28031292)
GO_REF:0000107
RGD
Ensembl
PMID:28031292 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28263186) RGD PMID:28263186 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H involved_in ISO
IEA
(PMID:32269044)
GO_REF:0000107
RGD
Ensembl
PMID:32269044 GO_REF:0000107 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISO
IBA
IEA
ISS
(PMID:15313915)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:11546783)
Ensembl
RGD
PMID:11546783 GO_REF:0000107 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO
IEA
(PMID:24904118)
GO_REF:0000107
GO:0010628 (PMID:24904118)
RGD
Ensembl
PMID:24904118 GO_REF:0000107 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24613385)
UniProt
Ensembl
RGD
PMID:24613385 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:24960163)
GO_Central
RGD
PMID:24960163 GO_REF:0000033 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800
JBrowse link
G Map1a microtubule-associated protein 1A involved_in ISO (PMID:26609151) RGD PMID:26609151 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (PMID:23695157) RGD PMID:23695157 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860
JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in IBA
ISO
GO_REF:0000033
(PMID:17592138)
GO_Central
RGD
PMID:17592138 GO_REF:0000033 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) RGD PMID:22522597 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO
GO_REF:0000107
(PMID:26678539)
Ensembl
RGD
PMID:26678539 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:17015834) RGD PMID:17015834 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Phf20l1 PHD finger protein 20-like 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24492612)
UniProt
Ensembl
RGD
PMID:24492612 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
JBrowse link
G Rgs19 regulator of G-protein signaling 19 involved_in ISO (PMID:11546783) RGD PMID:11546783 NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
ISO
GO_REF:0000024
(PMID:21804542)
UniProt
RGD
PMID:21804542 GO_REF:0000024 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rybp RING1 and YY1 binding protein involved_in ISO (PMID:27060496) RGD PMID:27060496 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO MGI:3818522 (PMID:17981124) RGD PMID:17981124 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16611981)
Ensembl
RGD
PMID:16611981 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 acts_upstream_of_or_within ISO (PMID:22285184) RGD PMID:22285184 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO
IEA
(PMID:11278372)
GO_REF:0000107
RGD
Ensembl
PMID:11278372 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
JBrowse link
G Tlk2 tousled-like kinase 2 involved_in ISO (PMID:20016786) RGD PMID:20016786 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
IBA
ISS
(PMID:23213251)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
RGD
Ensembl
GO_Central
UniProt
PMID:23213251 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (PMID:31537781) RGD PMID:31537781 NCBI chr 8:45,112,737...45,116,345 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:20351172)
UniProt
GO_Central
RGD
PMID:20351172 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23770237) RGD PMID:23770237 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Usp26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133) RGD PMID:28839133 NCBI chr  X:131,317,200...131,363,964
Ensembl chr  X:131,319,194...131,363,970
JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO (PMID:34102342) RGD PMID:34102342 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437
JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISO
IEA
(PMID:26678539)
GO_REF:0000107
RGD
Ensembl
PMID:26678539 GO_REF:0000107 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:33378666) RGD PMID:33378666 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) RGD PMID:17344476 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30249802)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30249802 GO_REF:0000024 GO_REF:0000107 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within
ISO UniProtKB:Q9BXM7 (PMID:25217637)
(PMID:23277542)
RGD PMID:23277542 PMID:25217637 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Efna1 ephrin A1 involved_in ISO
IEA
UniProtKB:P54764 (PMID:24217950)
GO_REF:0000107
RGD
Ensembl
PMID:24217950 GO_REF:0000107 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Ufsp2 UFM1-specific peptidase 2 involved_in ISO (PMID:36543799) RGD PMID:36543799 NCBI chr16:46,272,016...46,291,080
Ensembl chr16:46,272,016...46,291,059
JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pabpn1l PABPN1 like acts_upstream_of_or_within ISO (PMID:32558204) RGD PMID:32558204 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366
JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in ISO
IBA
(PMID:28007894)
GO_REF:0000033
RGD
GO_Central
PMID:28007894 GO_REF:0000033 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524
JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa8 annexin A8 involved_in ISO (PMID:2530088) RGD PMID:2530088 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167
JBrowse link
G Serpina1 serpin family A member 1 IDA RGD PMID:19240864 RGD:7411612 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 acts_upstream_of_or_within IDA
ISO
MGI:3613294 (PMID:20110462), (PMID:22228629) RGD PMID:20110462 PMID:22228629 PMID:12771515 RGD:724699 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 acts_upstream_of_or_within ISO (PMID:21705336) RGD PMID:21705336 NCBI chr14:30,967,682...30,974,326
Ensembl chr14:30,967,714...30,974,326
JBrowse link
G Spink6 serine peptidase inhibitor, Kazal type 6 acts_upstream_of_or_within ISO (PMID:24352040) RGD PMID:24352040 NCBI chr18:36,397,833...36,410,010
Ensembl chr18:36,397,910...36,409,819
JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 acts_upstream_of_or_within ISO MGI:3573756 (PMID:20179351) RGD PMID:20179351 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185
JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) RGD PMID:20100865 NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within
ISO (PMID:16173922)
(PMID:23277542)
(PMID:18560357)
RGD PMID:16173922 PMID:18560357 PMID:23277542 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24904118) RGD PMID:24904118 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:21628596) RGD PMID:21628596 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Pdcl3 phosducin-like 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23792958)
GO_REF:0000107
RGD
Ensembl
PMID:23792958 GO_REF:0000107 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:15195100) RGD PMID:15195100 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Prmt6 protein arginine methyltransferase 6 involved_in ISO (PMID:26070566) RGD PMID:26070566 NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
JBrowse link
G Psen1 presenilin 1 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Qrich2 glutamine rich 2 involved_in ISO (PMID:30683861) RGD PMID:30683861 NCBI chr10:101,669,240...101,697,643
Ensembl chr10:101,669,224...101,697,656
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl23 ribosomal protein L23 involved_in ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl5 ribosomal protein L5 involved_in ISO (PMID:18560357) RGD PMID:18560357 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:23129660)
UniProt
Ensembl
RGD
PMID:23129660 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:1343085 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
G Svip small VCP interacting protein involved_in IDA PMID:17000876 ParkinsonsUK-UCL PMID:17000876 RGD:10047192 NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) RGD PMID:17237821 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO (PMID:19100260) RGD PMID:19100260 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Usp14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) RGD PMID:19135427 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (PMID:16601693) RGD PMID:16601693 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520
JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    cellular process 19131
      metabolic process 11926
        macromolecule metabolic process 9784
          protein metabolic process 5279
            proteolysis 1731
              negative regulation of proteolysis 202
                negative regulation of membrane protein ectodomain proteolysis 7
                negative regulation of peptidase activity + 83
                negative regulation of protein processing + 25
                negative regulation of proteolysis involved in protein catabolic process + 79
Path 2
Term Annotations click to browse term
  biological_process 20052
    biological regulation 13543
      regulation of biological process 13123
        regulation of cellular process 12759
          regulation of metabolic process 6732
            regulation of primary metabolic process 5641
              regulation of protein metabolic process 2164
                negative regulation of protein metabolic process 873
                  negative regulation of proteolysis 202
                    negative regulation of membrane protein ectodomain proteolysis 7
                    negative regulation of peptidase activity + 83
                    negative regulation of protein processing + 25
                    negative regulation of proteolysis involved in protein catabolic process + 79
paths to the root