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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein kinase activity
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Accession:GO:0045860 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein kinase activity.
Synonyms:exact_synonym: up regulation of protein kinase activity;   upregulation of protein kinase activity
 narrow_synonym: stimulation of protein kinase activity

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positive regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 ISO RGD PMID:15228590 RGD:1304344 NCBI chrNW_004955442:16,845,728...16,898,301
Ensembl chrNW_004955442:16,843,152...16,898,430 		JBrowse link
G Axin2 axin 2 ISO RGD PMID:9566905 RGD:68736 NCBI chrNW_004955478:4,952,551...4,982,223
Ensembl chrNW_004955478:4,952,488...4,982,225 		JBrowse link
G Camkk1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:7642608 RGD:632489 NCBI chrNW_004955467:12,973,667...13,002,098
Ensembl chrNW_004955467:12,976,000...13,002,159 		JBrowse link
G Ccnb1 cyclin B1 ISO histone H1 RGD PMID:15291744 RGD:1578405 NCBI chrNW_004955446:140,661...149,500
Ensembl chrNW_004955446:140,093...149,500 		JBrowse link
G Dag1 dystroglycan 1 ISO RGD PMID:18556591 RGD:11541067 NCBI chrNW_004955532:1,446,553...1,465,310
Ensembl chrNW_004955532:1,397,900...1,466,312 		JBrowse link
G Daxx death domain associated protein ISO RGD PMID:21572393 RGD:9587767 NCBI chrNW_004955437:1,869,692...1,874,041
Ensembl chrNW_004955437:1,869,572...1,873,050 		JBrowse link
G Ppp1r9a protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:9653190 RGD:8554053 NCBI chrNW_004955432:11,607,269...11,891,568
Ensembl chrNW_004955432:11,608,382...11,886,044 		JBrowse link
G Sdc4 syndecan 4 ISO RGD PMID:12571249 RGD:1580031 NCBI chrNW_004955445:11,990,916...12,009,178
Ensembl chrNW_004955445:11,990,792...12,011,553 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:9314843 RGD:6478796 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255 		JBrowse link
G Ghr growth hormone receptor ISO RGD PMID:11244571 RGD:1624962 NCBI chrNW_004955426:26,553,509...26,873,619
Ensembl chrNW_004955426:26,689,581...26,871,684 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO RGD PMID:11818507 RGD:633057 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225 		JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ucn urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641 		JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity dependent neuroprotector homeobox ISO Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chrNW_004955445:7,498,223...7,530,828
Ensembl chrNW_004955445:7,492,257...7,531,862 		JBrowse link
G Camkk1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:16054095 RGD:2311420 NCBI chrNW_004955467:12,973,667...13,002,098
Ensembl chrNW_004955467:12,976,000...13,002,159 		JBrowse link
G Camkk2 calcium/calmodulin dependent protein kinase kinase 2 ISO RGD PMID:16054095 RGD:2311420 NCBI chrNW_004955482:7,000,010...7,029,623
Ensembl chrNW_004955482:7,000,010...7,029,623 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:12086672 RGD:1580677 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Hnf1a HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613 		JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcz protein kinase C zeta ISO in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chrNW_004955486:8,947,579...9,021,702
Ensembl chrNW_004955486:8,947,579...9,021,702 		JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chrNW_004955462:9,196,984...9,278,850
Ensembl chrNW_004955462:9,207,314...9,278,621 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc6 cell division cycle 6 ISO RGD PMID:22223646 RGD:10045360 NCBI chrNW_004955451:14,857,174...14,871,324
Ensembl chrNW_004955451:14,860,309...14,871,494 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 ISO RGD PMID:10721722 RGD:632478 NCBI chrNW_004955422:27,878,048...27,907,157
Ensembl chrNW_004955422:27,879,389...27,906,861 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO RGD PMID:22223646 RGD:10045360 NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542 		JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:19574994 RGD:2317913 NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chrNW_004955446:11,022,091...11,090,136
Ensembl chrNW_004955446:11,021,971...11,090,136 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225 		JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chrNW_004955407:30,804,769...31,178,420
Ensembl chrNW_004955407:30,803,653...30,942,854 		JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Ilk integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chrNW_004955414:22,316,243...22,322,979
Ensembl chrNW_004955414:22,316,047...22,322,979 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:23987506 RGD:11049533 NCBI chrNW_004955416:14,558,628...14,652,031
Ensembl chrNW_004955416:14,560,292...14,650,036 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:10969813 RGD:1600497 NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chrNW_004955446:11,022,091...11,090,136
Ensembl chrNW_004955446:11,021,971...11,090,136 		JBrowse link
G Prkcd protein kinase C delta ISO RGD PMID:16935468 RGD:1642549 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:11941412 RGD:150523765 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chrNW_004955413:25,290,733...25,315,267
Ensembl chrNW_004955413:25,290,828...25,313,969 		JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774 		JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO Akt1 RGD PMID:18443201 RGD:4108490 NCBI chrNW_004955437:9,872,649...9,878,459
Ensembl chrNW_004955437:9,873,908...9,878,459 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      primary metabolic process 6429
        protein metabolic process 2844
          protein modification process 1553
            protein phosphorylation 711
              positive regulation of protein phosphorylation 433
                positive regulation of protein kinase activity 38
                  activation of protein kinase activity + 11
                  positive regulation of activation of Janus kinase activity 0
                  positive regulation of cyclin-dependent protein kinase activity + 3
                  positive regulation of protein histidine kinase activity 0
                  positive regulation of protein serine/threonine kinase activity + 20
                  positive regulation of protein tyrosine kinase activity + 1
                  positive regulation of tau-protein kinase activity 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological process 8618
        regulation of metabolic process 4808
          regulation of cellular metabolic process 4272
            regulation of phosphorus metabolic process 830
              regulation of phosphate metabolic process 827
                regulation of phosphorylation 682
                  regulation of protein phosphorylation 633
                    positive regulation of protein phosphorylation 433
                      positive regulation of protein kinase activity 38
                        activation of protein kinase activity + 11
                        positive regulation of activation of Janus kinase activity 0
                        positive regulation of cyclin-dependent protein kinase activity + 3
                        positive regulation of protein histidine kinase activity 0
                        positive regulation of protein serine/threonine kinase activity + 20
                        positive regulation of protein tyrosine kinase activity + 1
                        positive regulation of tau-protein kinase activity 0
paths to the root