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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition


show annotations for term's descendants           Sort by:
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc11 anaphase promoting complex subunit 11 involved_in ISO
IEA		 (PMID:11739784)
GO_REF:0000107		 RGD
Ensembl		 PMID:11739784 GO_REF:0000107 NCBI chr10:106,373,610...106,384,633 JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:39,409,519...39,442,518
Ensembl chr12:33,748,735...33,781,781 		JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:39,793,518...39,821,614
Ensembl chr12:34,133,429...34,160,005 		JBrowse link
G Cdc16 cell division cycle 16 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:82,475,234...82,498,797
Ensembl chr16:75,773,028...75,796,550 		JBrowse link
G Cdc20 cell division cycle 20 involved_in ISO
IEA		 (PMID:9637688)
GO_REF:0000107		 RGD
Ensembl		 PMID:9637688 GO_REF:0000107 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc23 cell division cycle 23 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:26,511,019...26,534,872
Ensembl chr18:26,236,890...26,291,163 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:12925705) RGD PMID:12925705 NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA		 (PMID:17543862)
GO_REF:0000107		 RGD
Ensembl		 PMID:17543862 GO_REF:0000107 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Npb neuropeptide B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:106,382,307...106,385,566
Ensembl chr10:105,874,708...105,887,254 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IEA
ISS		 (PMID:19502785)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19502785 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:92,825,568...93,071,037
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA		 (PMID:20551165)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551165 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C involved_in ISO (PMID:12629039) RGD PMID:12629039 NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO
IEA		 (PMID:18022368)
GO_REF:0000107		 RGD
Ensembl		 PMID:18022368 GO_REF:0000107 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24374861)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24374861 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:204,312,723...204,316,519
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
negative regulation of mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26981768)		 UniProt
Ensembl
RGD		 PMID:26981768 GO_REF:0000024 GO_REF:0000107 NCBI chr18:70,069,957...70,080,303
Ensembl chr18:67,794,725...67,805,037 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19646878)		 UniProt
Ensembl
RGD		 PMID:19646878 GO_REF:0000024 GO_REF:0000107 NCBI chr15:36,067,372...36,086,563
Ensembl chr15:31,951,825...31,971,010 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cell cycle process 1322
        positive regulation of cell cycle process 287
          positive regulation of mitotic nuclear division 49
            positive regulation of mitotic metaphase/anaphase transition 17
              negative regulation of mitotic spindle assembly checkpoint signaling + 5
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          organelle organization 3713
            organelle fission 521
              nuclear division 461
                mitotic nuclear division 276
                  mitotic sister chromatid segregation 187
                    mitotic sister chromatid separation 56
                      regulation of mitotic sister chromatid separation 53
                        positive regulation of mitotic sister chromatid separation 17
                          positive regulation of mitotic metaphase/anaphase transition 17
                            negative regulation of mitotic spindle assembly checkpoint signaling + 5
paths to the root