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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition



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positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc11 anaphase promoting complex subunit 11 involved_in ISO
IBA
(PMID:11739784)
GO_REF:0000033
RGD
GO_Central
PMID:11739784 GO_REF:0000033 NCBI chr10:105,875,209...105,886,307 JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005
JBrowse link
G Cdc16 cell division cycle 16 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550
JBrowse link
G Cdc20 cell division cycle 20 involved_in ISO
IEA
(PMID:9637688)
GO_REF:0000107
RGD
Ensembl
PMID:9637688 GO_REF:0000107 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc23 cell division cycle 23 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:2673075 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA
(PMID:17543862)
GO_REF:0000107
RGD
Ensembl
PMID:17543862 GO_REF:0000107 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IEA
ISS
(PMID:19502785)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19502785 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA
(PMID:20551165)
GO_REF:0000107
RGD
Ensembl
PMID:20551165 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C involved_in ISO (PMID:12629039) RGD PMID:12629039 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24374861)
UniProt
RGD
PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cell cycle process 1345
        positive regulation of cell cycle process 296
          positive regulation of mitotic nuclear division 48
            positive regulation of mitotic metaphase/anaphase transition 14
              negative regulation of mitotic spindle assembly checkpoint signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cellular component organization or biogenesis 7188
        cellular component organization 6877
          organelle organization 3816
            organelle fission 536
              nuclear division 477
                mitotic nuclear division 277
                  mitotic sister chromatid segregation 185
                    mitotic sister chromatid separation 55
                      regulation of mitotic sister chromatid separation 52
                        positive regulation of mitotic sister chromatid separation 14
                          positive regulation of mitotic metaphase/anaphase transition 14
                            negative regulation of mitotic spindle assembly checkpoint signaling + 3
paths to the root