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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition

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positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in ISO (PMID:9637688) UniProt PMID:9637688 NCBI chrNW_004955537:2,941,265...2,945,158
Ensembl chrNW_004955537:2,941,265...2,945,158 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chrNW_004955496:5,468,759...5,514,915
Ensembl chrNW_004955496:5,469,239...5,513,574 		JBrowse link
G Cul3 cullin 3 involved_in ISO (PMID:17543862) UniProt PMID:17543862 NCBI chrNW_004955453:9,546,554...9,629,976
Ensembl chrNW_004955453:9,564,522...9,629,976 		JBrowse link
G Nsmce2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO (PMID:19502785) UniProt PMID:19502785 NCBI chrNW_004955461:199,356...451,716
Ensembl chrNW_004955461:201,764...451,776 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO (PMID:20551165) BHF-UCL PMID:20551165 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576 		JBrowse link
G Ube2c ubiquitin conjugating enzyme E2 C involved_in ISO (PMID:12629039) UniProt PMID:12629039 NCBI chrNW_004955445:11,474,826...11,479,479
Ensembl chrNW_004955445:11,469,063...11,478,759 		JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chrNW_004955460:9,340,728...9,672,478
Ensembl chrNW_004955460:9,340,681...9,672,134 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) UniProt PMID:18022368 NCBI chrNW_004955437:9,423,630...9,433,357 JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chrNW_004955477:10,982,530...11,002,747
Ensembl chrNW_004955477:10,999,168...11,002,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cell cycle process 1052
        positive regulation of cell cycle process 249
          positive regulation of mitotic nuclear division 40
            positive regulation of mitotic metaphase/anaphase transition 9
              negative regulation of mitotic spindle assembly checkpoint signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular component organization or biogenesis 5364
        cellular component organization 5235
          organelle organization 2919
            organelle fission 441
              nuclear division 391
                mitotic nuclear division 236
                  mitotic sister chromatid segregation 155
                    mitotic sister chromatid separation 45
                      regulation of mitotic sister chromatid separation 42
                        positive regulation of mitotic sister chromatid separation 9
                          positive regulation of mitotic metaphase/anaphase transition 9
                            negative regulation of mitotic spindle assembly checkpoint signaling + 3
paths to the root