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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition



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positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC11 anaphase promoting complex subunit 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,297,262...76,305,826
Ensembl chr17:82,002,135...82,007,921
JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:118,906,482...118,950,913
Ensembl chr12:122,279,227...122,324,428
JBrowse link
G ANAPC7 anaphase promoting complex subunit 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:107,946,756...107,977,489
Ensembl chr12:111,338,045...111,368,466
JBrowse link
G CDC16 cell division cycle 16 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:95,300,763...95,340,762
Ensembl chr13:114,369,774...114,407,267
JBrowse link
G CDC20 cell division cycle 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:42,660,338...42,664,618
Ensembl chr 1:44,039,971...44,044,497
JBrowse link
G CDC23 cell division cycle 23 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:133,566,022...133,591,528
Ensembl chr 5:139,699,421...139,724,991
JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 4:95,562,005...95,654,397
Ensembl chr 4:106,185,283...106,277,229
JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991
JBrowse link
G NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:121,777,986...122,052,094
Ensembl chr 8:124,529,268...124,803,114
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,152,219...42,156,246
Ensembl chr20:43,239,382...43,243,464
JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328
JBrowse link
G MAD2L1BP MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,219,638...43,230,988
Ensembl chr 6:44,509,839...44,521,590
JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,248,728...134,268,442 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cell cycle process 1277
        positive regulation of cell cycle process 281
          positive regulation of mitotic nuclear division 47
            positive regulation of mitotic metaphase/anaphase transition 14
              negative regulation of mitotic spindle assembly checkpoint signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          organelle organization 3612
            organelle fission 527
              nuclear division 473
                mitotic nuclear division 278
                  mitotic sister chromatid segregation 191
                    mitotic sister chromatid separation 55
                      regulation of mitotic sister chromatid separation 52
                        positive regulation of mitotic sister chromatid separation 14
                          positive regulation of mitotic metaphase/anaphase transition 14
                            negative regulation of mitotic spindle assembly checkpoint signaling + 3
paths to the root