ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of mitotic metaphase/anaphase transition
Accession: GO:0045841
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Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms: exact_synonym: down regulation of mitotic metaphase/anaphase transition; downregulation of mitotic metaphase/anaphase transition
narrow_synonym: inhibition of mitotic metaphase/anaphase transition
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FBXO5
F-box protein 5
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:43,138,338...43,149,546
Ensembl chr 1:43,138,889...43,149,297
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RAD21
RAD21 cohesin complex component
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr13:16,337,563...16,368,041
Ensembl chr13:16,338,972...16,368,035
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USP44
ubiquitin specific peptidase 44
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr15:35,401,486...35,454,351
Ensembl chr15:35,402,207...35,414,261
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
ISO
(PMID:19010891)
UniProt
PMID:19010891
NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192
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MAD2L1BP
MAD2L1 binding protein
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr12:12,085,825...12,089,907
Ensembl chr12:12,085,915...12,090,411
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PRAP1
proline rich acidic protein 1
involved_in
ISO
(PMID:24374861)
UniProt
PMID:24374861
NCBI chr28:40,927,744...40,931,355
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APC
APC regulator of WNT signaling pathway
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:17227893)
MGI Ensembl
PMID:17227893
GO_REF:0000107
NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993
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ATM
ATM serine/threonine kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
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BIRC5
baculoviral IAP repeat containing 5
involved_in
ISS
UniProt
GO_REF:0000024
NCBI chr 9:2,930,308...2,959,307
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BUB1
BUB1 mitotic checkpoint serine/threonine kinase
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr17:35,208,989...35,252,296
Ensembl chr17:35,208,991...35,252,975
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BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr30:7,361,982...7,410,162
Ensembl chr30:7,322,912...7,438,052
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BUB3
BUB3 mitotic checkpoint protein
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr28:32,693,104...32,703,293
Ensembl chr28:32,679,421...32,703,023
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CENPE
centromere protein E
involved_in
ISO
(MGI:2673075|PMID:12925705)
UniProt
PMID:12925705
MGI:2673075
NCBI chr32:24,447,373...24,530,407
Ensembl chr32:24,447,358...24,530,382
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DOCK2
dedicator of cytokinesis 2
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 4:41,779,950...42,177,957
Ensembl chr 4:41,780,436...42,235,177
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HASPIN
histone H3 associated protein kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:47,540,417...47,542,953
Ensembl chr 9:47,540,446...47,542,791
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IK
IK cytokine
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 2:35,805,631...35,818,205
Ensembl chr 2:35,805,689...35,818,050
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KHDC3L
KH domain containing 3 like, subcortical maternal complex member
acts_upstream_of_or_within
ISO
(PMID:19376971)
MGI
PMID:19376971
NCBI chr12:35,434,123...35,435,679
Ensembl chr12:35,434,123...35,468,943
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KLHL22
kelch like family member 22
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr26:30,248,253...30,281,989
Ensembl chr26:30,248,240...30,281,843
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KNTC1
kinetochore associated 1
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr26:6,777,667...6,867,798
Ensembl chr26:6,777,383...6,865,016
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LOC100684931
inactive serine/threonine-protein kinase TEX14-like
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 1:116,849,031...116,851,289
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LOC100687713
BUB3-interacting and GLEBS motif-containing protein ZNF207
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr11:1,027,387...1,029,505
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LOC119876650
inactive serine/threonine-protein kinase TEX14-like
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
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LOC476070
mitotic arrest deficient 2 like 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:11201745)
TreeGrafter MGI
PMID:11201745
GO_REF:0000118
NCBI chr18:55,653,677...55,661,017
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192
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MAD2L1
mitotic arrest deficient 2 like 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
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PLK1
polo like kinase 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:22,165,338...22,176,847
Ensembl chr 6:22,165,338...22,176,441
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PSMG2
proteasome assembly chaperone 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12147697)
Ensembl MGI
PMID:12147697
GO_REF:0000107
NCBI chr 7:78,092,877...78,112,831
Ensembl chr 7:78,092,876...78,112,702
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PSTK
phosphoseryl-tRNA kinase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr28:32,535,258...32,546,738
Ensembl chr28:32,535,161...32,546,741
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SPDL1
spindle apparatus coiled-coil protein 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 4:42,214,997...42,235,282
Ensembl chr 4:41,780,436...42,235,177
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TEX14
testis expressed 14, intercellular bridge forming factor
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 9:33,174,813...33,289,202
Ensembl chr 9:33,174,814...33,262,870
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TPR
translocated promoter region, nuclear basket protein
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
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TRIP13
thyroid hormone receptor interactor 13
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr34:11,522,940...11,539,885
Ensembl chr34:11,522,940...11,539,885
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TTK
TTK protein kinase
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr12:40,915,733...40,959,423
Ensembl chr12:40,915,439...40,957,279
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ZNF207
zinc finger protein 207
involved_in
IEA
TreeGrafter
GO_REF:0000118
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ZW10
zw10 kinetochore protein
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr 5:19,496,531...19,527,205
Ensembl chr 5:19,496,611...19,527,200
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ZWILCH
zwilch kinetochore protein
involved_in
IEA
Ensembl TreeGrafter UniProt
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr30:30,772,219...30,811,055
Ensembl chr30:30,772,057...30,809,040
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ZWINT
ZW10 interacting kinetochore protein
involved_in
ISO
(PMID:15485811)
HGNC-UCL
PMID:15485811
NCBI chr26:32,432,385...32,459,377
Ensembl chr26:32,432,406...32,453,162
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DYNC1LI1
dynein cytoplasmic 1 light intermediate chain 1
involved_in
ISO
(PMID:19229290)
UniProt
PMID:19229290
NCBI chr23:12,235,539...12,283,851
Ensembl chr23:12,235,104...12,277,031
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GEN1
GEN1 Holliday junction 5' flap endonuclease
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:13,201,540...13,233,028
Ensembl chr17:13,201,777...13,232,120
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LOC476070
mitotic arrest deficient 2 like 1
involved_in
ISO
(PMID:20870947) (PMID:22898774), (PMID:8824189) (MGI:4839685|PMID:20870947)
UniProt ComplexPortal
PMID:8824189 PMID:20870947 PMID:22898774
MGI:4839685
NCBI chr18:55,653,677...55,661,017
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MAD1L1
mitotic arrest deficient 1 like 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192
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NDC80
NDC80 kinetochore complex component
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:69,268,218...69,317,126
Ensembl chr 7:69,268,242...69,317,072
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PCID2
PCI domain containing 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719
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TPR
translocated promoter region, nuclear basket protein
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
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XRCC3
X-ray repair cross complementing 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 8:71,441,732...71,452,922
Ensembl chr 8:71,442,429...71,449,408
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ANAPC15
anaphase promoting complex subunit 15
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr21:25,971,680...25,975,556
Ensembl chr21:25,972,458...25,975,558
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CCNB1
cyclin B1
involved_in
ISO
(PMID:18195732)
BHF-UCL
PMID:18195732
NCBI chr 2:54,256,957...54,264,749
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CDK5RAP2
CDK5 regulatory subunit associated protein 2
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr11:73,548,003...73,693,044
Ensembl chr11:73,548,038...73,690,199
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KNL1
kinetochore scaffold 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr30:7,753,515...7,825,019
Ensembl chr30:7,753,432...7,821,588
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LCMT1
leucine carboxyl methyltransferase 1
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:17724024)
MGI Ensembl
PMID:17724024
GO_REF:0000107
NCBI chr 6:21,026,125...21,066,884
Ensembl chr 6:21,026,186...21,066,876
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PRP4K
pre-mRNA processing factor kinase PRP4K
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr35:4,274,664...4,311,813
Ensembl chr35:4,271,685...4,307,750
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USP44
ubiquitin specific peptidase 44
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr15:35,401,486...35,454,351
Ensembl chr15:35,402,207...35,414,261
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