Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of heart contraction
go back to main search page
Accession:GO:0045822 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
Synonyms:exact_synonym: down regulation of heart contraction;   downregulation of heart contraction
 narrow_synonym: inhibition of heart contraction
 related_synonym: negative regulation of cardiac contraction


show annotations for term's descendants           Sort by:
negative regulation of heart contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide acts_upstream_of_or_within IMP (PMID:15485817) MGI PMID:15485817 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000 		JBrowse link
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide acts_upstream_of_or_within IMP (PMID:10360172) MGI PMID:10360172 NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 acts_upstream_of_or_within IGI (PMID:10555147) MGI PMID:10555147 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific involved_in IMP (MGI:5442270|PMID:21903937) BHF-UCL PMID:21903937 MGI:5442270 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995 		JBrowse link
G Pln phospholamban acts_upstream_of_or_within IGI
IMP		 (PMID:10555147)
(PMID:8062415)		 MGI PMID:8062415 PMID:10555147 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 involved_in ISO RGD
MGI		 PMID:31754830 GO_REF:0000096 MGI:4417868 RGD:329403060 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde5a phosphodiesterase 5A, cGMP-specific involved_in IMP (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023 		JBrowse link
G Sri sorcin involved_in IMP (MGI:5319286|PMID:22326846) BHF-UCL PMID:22326846 MGI:5319286 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in IDA (MGI:5142149|PMID:21616078) UniProt PMID:21616078 MGI:5142149 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in IMP (MGI:3626025|PMID:9449684) BHF-UCL PMID:9449684 MGI:3626025 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Fkbp1b FK506 binding protein 1b involved_in IMP (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Gjd3 gap junction protein, delta 3 involved_in IMP (MGI:3623651|PMID:16571663) BHF-UCL PMID:16571663 MGI:3623651 NCBI chr11:98,870,773...98,873,846
Ensembl chr11:98,873,006...98,873,842 		JBrowse link
G Npff neuropeptide FF-amide peptide precursor involved_in ISO RGD
MGI		 PMID:8680863 GO_REF:0000096 MGI:4417868 RGD:2316573 NCBI chr15:102,432,274...102,433,056
Ensembl chr15:102,432,274...102,433,377 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO RGD
MGI		 PMID:19015400 GO_REF:0000096 MGI:4417868 RGD:4108483 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pln phospholamban involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 acts_upstream_of_or_within IMP (PMID:20877009) MGI PMID:20877009 NCBI chr 7:27,055,808...27,147,128
Ensembl chr 7:27,055,808...27,147,111 		JBrowse link
G Spx spexin hormone involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:142,359,114...142,365,466
Ensembl chr 6:142,359,167...142,365,456 		JBrowse link
G Sri sorcin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379 		JBrowse link
G Tac1 tachykinin 1 involved_in ISO RGD
MGI		 PMID:2471579 GO_REF:0000096 MGI:4417868 RGD:2305984 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO RGD
MGI		 PMID:7875478 GO_REF:0000096 MGI:4417868 RGD:14975128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO RGD
MGI		 PMID:27335281 GO_REF:0000096 MGI:4417868 RGD:13792700 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068 		JBrowse link
G Uts2 urotensin 2 involved_in ISO RGD
MGI		 PMID:12217424 GO_REF:0000096 MGI:4417868 RGD:2306871 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267 		JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in ISO RGD
MGI		 PMID:9316844 GO_REF:0000096 MGI:4417868 RGD:2303391 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenergic receptor, alpha 1a acts_upstream_of_or_within IMP (PMID:12093905) MGI PMID:12093905 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617 		JBrowse link
negative regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk2 G protein-coupled receptor kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenergic receptor, alpha 1d acts_upstream_of_or_within IMP (PMID:12595294) MGI PMID:12595294 NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203 		JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IMP (MGI:5583915|PMID:24836577) ARUK-UCL PMID:24836577 MGI:5583915 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790 		JBrowse link
Term paths to the root