Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of endocytosis
go back to main search page
Accession:GO:0045806 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
Synonyms:exact_synonym: down regulation of endocytosis;   downregulation of endocytosis
 narrow_synonym: inhibition of endocytosis


show annotations for term's descendants           Sort by:
 
negative regulation of endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:5694857|PMID:26260791)
UniProt
RGD
PMID:26260791 GO_REF:0000024, MGI:MGI:5694857 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Epha3 Eph receptor A3 IEA
ISO
GO_REF:0000107
(PMID:11877430)
Ensembl
RGD
PMID:11877430 GO_REF:0000107 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Lgals3 galectin 3 ISO
IBA
IEA
(PMID:19706535)
PMID:21873635
GO_REF:0000107
(MGI:MGI:4355752|PMID:19706535)
RGD
Ensembl
PMID:19706535, PMID:21873635 GO_REF:0000107, MGI:MGI:4355752, RGD:13792537 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 ISO (PMID:15256501) RGD PMID:15256501 NCBI chr 3:11,970,401...12,009,463
Ensembl chr 3:11,972,813...12,007,570
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 IDA PMID:26195140 UniProt PMID:26195140 RGD:13210552 NCBI chr 2:3,400,883...4,089,949
Ensembl chr 2:3,400,977...4,088,989
JBrowse link
G Mtmr2 myotubularin related protein 2 IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 ISO
IEA
(MGI:MGI:1929303|PMID:11082044)
GO_REF:0000107
RGD
Ensembl
PMID:11082044 GO_REF:0000107, MGI:MGI:1929303 NCBI chr20:7,241,248...7,286,702
Ensembl chr20:7,279,820...7,286,586
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 ISO (MGI:MGI:1929303|PMID:11082044) RGD PMID:11082044 MGI:MGI:1929303 NCBI chr 7:124,224,210...124,317,407
Ensembl chr 7:124,223,633...124,317,379
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 ISO (MGI:MGI:1929303|PMID:11082044), (MGI:MGI:3688821|PMID:16627472) RGD PMID:11082044, PMID:16627472 MGI:MGI:1929303, MGI:MGI:3688821 NCBI chr 3:80,072,425...80,081,058
Ensembl chr 3:80,072,489...80,081,047
JBrowse link
G Rubcn rubicon autophagy regulator ISO
IBA
(PMID:19270696)
PMID:21873635
RGD PMID:19270696, PMID:21873635 RGD:13792537 NCBI chr11:71,150,506...71,199,254
Ensembl chr11:71,151,132...71,197,035
JBrowse link
G Scamp5 secretory carrier membrane protein 5 IEA
ISO
GO_REF:0000107
(PMID:19240033)
Ensembl
RGD
PMID:19240033 GO_REF:0000107 NCBI chr 8:62,221,820...62,266,269
Ensembl chr 8:62,220,892...62,248,017
JBrowse link
G Snx33 sorting nexin 33 ISO (PMID:18353773), (PMID:18419754) RGD PMID:18353773, PMID:18419754 NCBI chr 8:61,584,656...61,596,055
Ensembl chr 8:61,584,656...61,595,032
JBrowse link
G Syt11 synaptotagmin 11 IDA
ISO
PMID:29311685
(MGI:MGI:6114813|PMID:29311685)
RGD PMID:29311685, PMID:29311685 MGI:MGI:6114813, RGD:14929208 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
negative regulation of caveolin-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prom2 prominin 2 IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 3:120,087,633...120,107,495
Ensembl chr 3:120,092,582...120,106,697
JBrowse link
G Unc119 unc-119 lipid binding chaperone ISO
IBA
ISS
(MGI:MGI:5559669|PMID:19781630)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:19781630, PMID:21873635 GO_REF:0000024, MGI:MGI:5559669, RGD:13792537 NCBI chr10:65,606,919...65,612,324
Ensembl chr10:65,606,898...65,612,324
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neu3 neuraminidase 3 ISO
IEA
(PMID:26251452)
GO_REF:0000107
RGD
Ensembl
PMID:26251452 GO_REF:0000107 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 IMP RGD PMID:15066995 RGD:13504745 NCBI chr 1:144,069,641...144,200,402
Ensembl chr 1:144,069,638...144,200,397
JBrowse link
G Syt11 synaptotagmin 11 IMP PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Ubqln2 ubiquilin 2 ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
G Unc119 unc-119 lipid binding chaperone ISO
IBA
ISS
(MGI:MGI:5559669|PMID:19781630)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:19781630, PMID:21873635 GO_REF:0000024, MGI:MGI:5559669, RGD:13792537 NCBI chr10:65,606,919...65,612,324
Ensembl chr10:65,606,898...65,612,324
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link
G Ubqln2 ubiquilin 2 ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IDA
IEA
(PMID:21810484)
(MGI:MGI:5306885|PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484, PMID:21810484 GO_REF:0000107, MGI:MGI:5306885, RGD:14697730 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G App amyloid beta precursor protein NOT ISO UniProtKB:P35951|UniProtKB:P49768 (PMID:20005821) RGD PMID:20005821 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Psen1 presenilin 1 NOT ISO UniProtKB:P05067|UniProtKB:P35951 (PMID:20005821) RGD PMID:20005821 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
negative regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
negative regulation of phagocytosis, engulfment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (PMID:22302738) RGD PMID:22302738 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Siglec8 sialic acid binding Ig-like lectin 8 ISO (MGI:MGI:5529741|PMID:24227736) RGD PMID:24227736 MGI:MGI:5529741 NCBI chr 1:99,576,946...99,587,441
Ensembl chr 1:99,578,372...99,587,205
JBrowse link
negative regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Prom2 prominin 2 IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 3:120,087,633...120,107,495
Ensembl chr 3:120,092,582...120,106,697
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:9045618 RGD:11568652 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13a ankyrin repeat domain 13a ISO (PMID:22298428) RGD PMID:22298428 NCBI chr12:47,558,587...47,588,486
Ensembl chr12:47,558,590...47,588,335
JBrowse link
G Ankrd13b ankyrin repeat domain 13B ISO (PMID:22298428) RGD PMID:22298428 NCBI chr10:62,674,416...62,691,949
Ensembl chr10:62,674,561...62,690,845
JBrowse link
G Ankrd13d ankyrin repeat domain 13D ISO (PMID:22298428) RGD PMID:22298428 NCBI chr 1:219,520,316...219,532,718
Ensembl chr 1:219,520,075...219,532,609
JBrowse link
G Atxn2 ataxin 2 ISO (PMID:18602463) RGD PMID:18602463 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 IDA PMID:11526121 UniProt PMID:11526121 RGD:8554437 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP RGD PMID:17881561 RGD:12050150 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO
IBA
ComplexPortal:CPX-1134|UniProtKB:P04925 (PMID:23386614)
PMID:21873635
RGD PMID:23386614, PMID:21873635 RGD:13792537 NCBI chr14:80,911,281...80,923,290
Ensembl chr14:80,911,270...80,924,831
JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 ISO MGI:MGI:2389174 (MGI:MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:MGI:5515239 NCBI chr 4:108,300,927...108,316,373
Ensembl chr 4:108,301,129...108,316,373
JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 ISO MGI:MGI:2389173 (MGI:MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:MGI:5515239 NCBI chr18:28,012,877...28,017,925
Ensembl chr18:28,012,877...28,017,925
JBrowse link
G Mtmr2 myotubularin related protein 2 IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Sdcbp syndecan binding protein ISO
ISS
(PMID:25893292)
GO_REF:0000024
RGD
UniProt
PMID:25893292 GO_REF:0000024 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485
JBrowse link
G Wdr54 WD repeat domain 54 ISO (PMID:30458214) RGD PMID:30458214 NCBI chr 4:114,847,722...114,871,989
Ensembl chr 4:114,850,815...114,853,868
Ensembl chr 4:114,850,815...114,853,868
JBrowse link
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc2 apolipoprotein C2 ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apoc3 apolipoprotein C3 ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein ISO
IEA
(PMID:10436022)
GO_REF:0000107
RGD
Ensembl
PMID:10436022 GO_REF:0000107 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO MGI:MGI:3051384 (MGI:MGI:3620385|PMID:16533754) RGD PMID:16533754 MGI:MGI:3620385 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
negative regulation of synaptic vesicle endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt11 synaptotagmin 11 IMP PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of transport 552
        negative regulation of endocytosis 46
          negative regulation of caveolin-mediated endocytosis 2
          negative regulation of low-density lipoprotein receptor activity 4
          negative regulation of phagocytosis, engulfment + 2
          negative regulation of pinocytosis + 6
          negative regulation of receptor-mediated endocytosis + 25
          negative regulation of synaptic vesicle endocytosis + 1
          negative regulation of ubiquitin-dependent endocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          vesicle-mediated transport 1652
            regulation of vesicle-mediated transport 641
              regulation of endocytosis 233
                negative regulation of endocytosis 46
                  negative regulation of caveolin-mediated endocytosis 2
                  negative regulation of low-density lipoprotein receptor activity 4
                  negative regulation of phagocytosis, engulfment + 2
                  negative regulation of pinocytosis + 6
                  negative regulation of receptor-mediated endocytosis + 25
                  negative regulation of synaptic vesicle endocytosis + 1
                  negative regulation of ubiquitin-dependent endocytosis 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.