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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of endocytosis
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Accession:GO:0045806 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
Synonyms:exact_synonym: down regulation of endocytosis;   downregulation of endocytosis
 narrow_synonym: inhibition of endocytosis


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negative regulation of endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5694857|PMID:26260791)
UniProt
RGD
PMID:26260791 GO_REF:0000024 MGI:5694857 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Epha3 Eph receptor A3 involved_in IEA
ISO
GO_REF:0000107
(PMID:11877430)
Ensembl
RGD
PMID:11877430 GO_REF:0000107 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Lgals3 galectin 3 involved_in IBA
ISO
IEA
PMID:21873635
(MGI:4355752|PMID:19706535)
GO_REF:0000107
(PMID:19706535)
RGD
Ensembl
PMID:19706535 PMID:21873635 GO_REF:0000107 MGI:4355752, RGD:13792537 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:15256501) RGD PMID:15256501 NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 involved_in IDA PMID:26195140 UniProt PMID:26195140 RGD:13210552 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1929303|PMID:11082044)
Ensembl
RGD
PMID:11082044 GO_REF:0000107 MGI:1929303 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 acts_upstream_of_or_within ISO (MGI:1929303|PMID:11082044) RGD PMID:11082044 MGI:1929303 NCBI chr 7:114,505,525...114,599,087
Ensembl chr 7:114,505,152...114,598,546
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 acts_upstream_of_or_within
involved_in
ISO (MGI:1929303|PMID:11082044)
(MGI:3688821|PMID:16627472)
RGD PMID:11082044 PMID:16627472 MGI:1929303 MGI:3688821 NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811
JBrowse link
G Rubcn rubicon autophagy regulator involved_in IBA
ISO
PMID:21873635
(PMID:19270696)
RGD PMID:19270696 PMID:21873635 RGD:13792537 NCBI chr11:67,907,534...67,964,347
Ensembl chr11:67,907,516...67,964,314
JBrowse link
G Scamp5 secretory carrier membrane protein 5 involved_in ISO
IEA
(PMID:19240033)
GO_REF:0000107
RGD
Ensembl
PMID:19240033 GO_REF:0000107 NCBI chr 8:57,845,831...57,884,516
Ensembl chr 8:57,846,659...57,872,027
JBrowse link
G Snx33 sorting nexin 33 involved_in ISO (PMID:18353773), (PMID:18419754) RGD PMID:18353773 PMID:18419754 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538
JBrowse link
G Syt11 synaptotagmin 11 involved_in IDA
ISO
PMID:29311685
(MGI:6114813|PMID:29311685)
RGD PMID:29311685 PMID:29311685 MGI:6114813, RGD:14929208 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
negative regulation of caveolin-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prom2 prominin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787
JBrowse link
G Unc119 unc-119 lipid binding chaperone involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5559669|PMID:19781630)
PMID:21873635
UniProt
RGD
PMID:19781630 PMID:21873635 GO_REF:0000024 MGI:5559669, RGD:13792537 NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neu3 neuraminidase 3 involved_in ISO (PMID:26251452) RGD PMID:26251452 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 IMP RGD PMID:15066995 RGD:13504745 NCBI chr 1:136,124,502...136,255,669
Ensembl chr 1:136,124,499...136,255,584
JBrowse link
G Syt11 synaptotagmin 11 involved_in IMP PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505
JBrowse link
G Unc119 unc-119 lipid binding chaperone involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5559669|PMID:19781630)
PMID:21873635
UniProt
RGD
PMID:19781630 PMID:21873635 GO_REF:0000024 MGI:5559669, RGD:13792537 NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505
JBrowse link
negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
IDA
IEA
ISO
PMID:21810484
GO_REF:0000107
(MGI:5306885|PMID:21810484)
(PMID:21810484)
Ensembl
RGD
PMID:21810484 PMID:21810484 GO_REF:0000107 MGI:5306885, RGD:14697730 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of ISO (PMID:11222466) RGD PMID:11222466 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G App amyloid beta precursor protein NOT|involved_in ISO UniProtKB:P35951|UniProtKB:P49768 (PMID:20005821) RGD PMID:20005821 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Itgav integrin subunit alpha V acts_upstream_of_or_within ISO (PMID:15215180) RGD PMID:15215180 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 acts_upstream_of_or_within ISO (PMID:15215180) RGD PMID:15215180 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Psen1 presenilin 1 NOT|involved_in ISO UniProtKB:P05067|UniProtKB:P35951 (PMID:20005821) RGD PMID:20005821 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
negative regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
negative regulation of phagocytosis, engulfment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:22302738) RGD PMID:22302738 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Siglec8 sialic acid binding Ig-like lectin 8 acts_upstream_of_or_within ISO (MGI:5529741|PMID:24227736) RGD PMID:24227736 MGI:5529741 NCBI chr 1:94,092,737...94,103,134
Ensembl chr 1:94,093,395...94,103,034
JBrowse link
negative regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:23583380)
GO_REF:0000107
RGD
Ensembl
PMID:23583380 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17693624)
GO_REF:0000107
RGD
Ensembl
PMID:17693624 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Prom2 prominin 2 involved_in ISO
IEA
(PMID:23583380)
GO_REF:0000107
RGD
Ensembl
PMID:23583380 GO_REF:0000107 NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:9045618 RGD:11568652 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13a ankyrin repeat domain 13a involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr12:41,798,196...41,828,327
Ensembl chr12:41,798,199...41,829,327
JBrowse link
G Ankrd13b ankyrin repeat domain 13B involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr10:62,319,660...62,338,342
Ensembl chr10:62,319,647...62,340,253
JBrowse link
G Ankrd13d ankyrin repeat domain 13D involved_in ISO (PMID:22298428) RGD PMID:22298428 NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933
JBrowse link
G Atxn2 ataxin 2 involved_in ISO (PMID:18602463) RGD PMID:18602463 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IDA PMID:11526121 UniProt PMID:11526121 RGD:8554437 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP RGD PMID:17881561 RGD:12050150 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO
IBA
ComplexPortal:CPX-1134|UniProtKB:P04925 (PMID:23386614)
PMID:21873635
RGD PMID:23386614 PMID:21873635 RGD:13792537 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 acts_upstream_of_or_within ISO MGI:2389174 (MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:5515239 NCBI chr 4:109,701,815...109,718,924
Ensembl chr 4:109,701,815...109,717,184
JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 acts_upstream_of_or_within ISO MGI:2389173 (MGI:5515239|PMID:23931994) RGD PMID:23931994 MGI:5515239 NCBI chr18:26,817,816...26,822,864
Ensembl chr18:26,817,816...26,822,864
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Rin3 Ras and Rab interactor 3 acts_upstream_of_or_within ISO (PMID:23185384) RGD PMID:23185384 NCBI chr 6:121,431,803...121,540,957
Ensembl chr 6:121,431,339...121,540,957
JBrowse link
G Sdcbp syndecan binding protein involved_in ISS
ISO
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 GO_REF:0000024 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Wdr54 WD repeat domain 54 involved_in ISO (PMID:30458214) RGD PMID:30458214 NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562
JBrowse link
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
IEA
(PMID:10436022)
GO_REF:0000107
RGD
Ensembl
PMID:10436022 GO_REF:0000107 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (MGI:3620385|PMID:16533754) RGD PMID:16533754 MGI:3620385 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
negative regulation of synaptic vesicle endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt11 synaptotagmin 11 involved_in IMP PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5613
      negative regulation of transport 529
        negative regulation of endocytosis 50
          negative regulation of caveolin-mediated endocytosis 2
          negative regulation of phagocytosis, engulfment + 2
          negative regulation of pinocytosis + 6
          negative regulation of receptor-mediated endocytosis + 31
          negative regulation of synaptic vesicle endocytosis + 1
          negative regulation of ubiquitin-dependent endocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      establishment of localization 4864
        transport 4700
          vesicle-mediated transport 1672
            regulation of vesicle-mediated transport 637
              regulation of endocytosis 241
                negative regulation of endocytosis 50
                  negative regulation of caveolin-mediated endocytosis 2
                  negative regulation of phagocytosis, engulfment + 2
                  negative regulation of pinocytosis + 6
                  negative regulation of receptor-mediated endocytosis + 31
                  negative regulation of synaptic vesicle endocytosis + 1
                  negative regulation of ubiquitin-dependent endocytosis 0
paths to the root