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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of bone resorption
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Accession:GO:0045780 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone resorption.
Synonyms:exact_synonym: up regulation of bone resorption;   upregulation of bone resorption
 narrow_synonym: activation of bone resorption;   stimulation of bone resorption

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positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009189|PMID:11341326), (MGI:5009349|PMID:20683884) RGD PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein IMP RGD PMID:10500999 RGD:1625797 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5575464|PMID:22467241)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22467241 GO_REF:0000024 GO_REF:0000107 MGI:5575464 NCBI chr  X:156,407,973...156,415,053
Ensembl chr  X:156,407,937...156,415,145 		JBrowse link
G Car2 carbonic anhydrase 2 IMP RGD PMID:8674544 RGD:1600722 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:3588832|PMID:16061724), (MGI:5426134|PMID:17164993), (MGI:5426135|PMID:16937266) RGD PMID:16061724 PMID:16937266 PMID:17164993 MGI:3588832 MGI:5426134 MGI:5426135 NCBI chr 7:78,642,016...78,651,763
Ensembl chr 7:78,649,875...78,650,906 		JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
ISO		 GO_REF:0000024
(MGI:5806241|PMID:27777970)		 UniProt
RGD		 PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr19:56,238,353...56,259,867
Ensembl chr19:56,243,408...56,259,196 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO MGI:3526402 (MGI:5780798|PMID:21308776) RGD PMID:21308776 MGI:5780798 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:2981075 RGD:10395245 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa involved_in ISO (MGI:5641770|PMID:25824719) RGD PMID:25824719 MGI:5641770 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051 		JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO MGI:1857434 (MGI:3692338|PMID:16630814) RGD PMID:16630814 MGI:3692338 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131 		JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236 (MGI:4397742|PMID:19834056) RGD PMID:19834056 MGI:4397742 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:8603604 RGD:5024929 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2673982 (MGI:4365357|PMID:18505367) RGD PMID:18505367 MGI:4365357 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (MGI:3719740|PMID:15878314) RGD PMID:15878314 MGI:3719740 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096 		JBrowse link
G Mc4r melanocortin 4 receptor involved_in ISO (PMID:16614075)
(MGI:3696590|PMID:16614075)		 RGD PMID:16614075 MGI:3696590 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725 		JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (MGI:2178877|PMID:11805147) RGD PMID:11805147 MGI:2178877 NCBI chr 1:64,182,174...64,188,658
Ensembl chr 1:64,182,422...64,188,658 		JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5806241|PMID:27777970)		 UniProt
RGD		 PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr10:91,451,890...91,500,675
Ensembl chr10:91,451,865...91,500,661 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr18:56,626,725...56,650,524
Ensembl chr18:56,626,712...56,728,968 		JBrowse link
G Prkca protein kinase C, alpha involved_in ISO (MGI:5284791|PMID:16014375) RGD PMID:16014375 MGI:5284791 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11792579 RGD:729815 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11792563, PMID:21873635 RGD:1581129, RGD:13792537 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3703840|PMID:17353363)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17353363 GO_REF:0000024 GO_REF:0000107 MGI:3703840 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
G Tf transferrin involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223 		JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of_or_within ISO MGI:3880885 (MGI:5495340|PMID:23395171) RGD PMID:23395171 MGI:5495340 NCBI chr 5:28,850,864...28,898,203
Ensembl chr 5:28,850,950...28,867,227 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2178877|PMID:11805147)		 RGD PMID:11805147, PMID:21873635 MGI:2178877, RGD:13792537 NCBI chr13:25,778,306...25,835,802
Ensembl chr13:25,778,317...25,835,957 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IMP
ISO		 (PMID:17241109) RGD PMID:17241109, PMID:11092398 RGD:730134 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    positive regulation of biological process 6574
      positive regulation of bone resorption 27
Path 2
Term Annotations click to browse term
  biological_process 19633
    biological regulation 13611
      regulation of biological quality 4333
        homeostatic process 2085
          anatomical structure homeostasis 470
            tissue homeostasis 287
              bone resorption 80
                regulation of bone resorption 53
                  positive regulation of bone resorption 27
paths to the root