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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of bone resorption
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Accession:GO:0045780 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone resorption.
Synonyms:exact_synonym: up regulation of bone resorption;   upregulation of bone resorption
 narrow_synonym: activation of bone resorption;   stimulation of bone resorption



show annotations for term's descendants           Sort by:
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002627.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:86,040,445...86,042,607 JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO
IEA
(PMID:11341326), (PMID:20683884)
GO_REF:0000107
RGD
Ensembl
PMID:11341326 PMID:20683884 GO_REF:0000107 NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485
JBrowse link
G Ahsg alpha-2-HS-glycoprotein IMP RGD PMID:10500999 RGD:1625797 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039
JBrowse link
G Car2 carbonic anhydrase 2 IMP RGD PMID:8674544 RGD:1600722 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (PMID:16061724), (PMID:16937266), (PMID:17164993) RGD PMID:16061724 PMID:16937266 PMID:17164993 NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:72,671,477...72,707,009
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27777970)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr19:68,383,293...68,404,133
Ensembl chr19:68,383,349...68,404,125
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO MGI:3526402 (PMID:21308776) RGD PMID:21308776 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:134,192,518...134,200,529
JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:2981075 RGD:10395245 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO
IEA
(PMID:25824719)
GO_REF:0000107
RGD
Ensembl
PMID:25824719 GO_REF:0000107 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651
JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO
IEA
MGI:1857434 (PMID:16630814)
GO_REF:0000107
RGD
Ensembl
PMID:16630814 GO_REF:0000107 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:114,003,262...114,007,072
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236 (PMID:19834056) RGD PMID:19834056 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,176,577...1,204,066
JBrowse link
G Itgb3 integrin subunit beta 3 involved_in IMP
IEA
GO_REF:0000117 UniProt
RGD
PMID:8603604 GO_REF:0000117, RGD:5024929 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2673982 (PMID:18505367) RGD PMID:18505367 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO
IEA
MGI:2180017 (PMID:15878314)
GO_REF:0000107
RGD
Ensembl
PMID:15878314 GO_REF:0000107 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:212,459,185...212,475,302
JBrowse link
G Mc4r melanocortin 4 receptor involved_in ISO (PMID:16614075) RGD PMID:16614075 NCBI chr18:60,419,832...60,421,719 JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (PMID:11805147) RGD PMID:11805147 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:74,515,001...74,529,119
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27777970)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:27777970 GO_REF:0000024 GO_REF:0000107 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,814,699...88,862,544
JBrowse link
G Prkca protein kinase C, alpha involved_in ISO (PMID:16014375) RGD PMID:16014375 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11792579 RGD:729815 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135
JBrowse link
G Rufy4 RUN and FYVE domain containing 4 involved_in ISO
IEA
(PMID:38744829)
GO_REF:0000107
RGD
Ensembl
PMID:38744829 GO_REF:0000107 NCBI chr 9:75,702,937...75,727,719
Ensembl chr 9:83,154,445...83,172,897
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11792563 GO_REF:0000033, RGD:1581129 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:8514886 RGD:150524326 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17353363)
UniProt
Ensembl
RGD
PMID:17353363 GO_REF:0000024 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278
JBrowse link
G Tmem64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3880885 (PMID:23395171)
GO_Central
RGD
PMID:23395171 GO_REF:0000033 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:33,496,032...33,542,389
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
GO_REF:0000033
(PMID:11805147)
GO_REF:0000107
GO_Central
RGD
Ensembl
PMID:11805147 GO_REF:0000033 GO_REF:0000107 NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IMP
ISO
IEA
(PMID:17241109)
GO_REF:0000107
RGD
Ensembl
PMID:17241109 PMID:11092398 GO_REF:0000107, RGD:730134 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    positive regulation of biological process 6855
      positive regulation of multicellular organismal process 1938
        positive regulation of bone resorption 26
Path 2
Term Annotations click to browse term
  biological_process 20668
    homeostatic process 2059
      multicellular organismal-level homeostasis 999
        anatomical structure homeostasis 304
          tissue homeostasis 304
            bone resorption 83
              regulation of bone resorption 54
                positive regulation of bone resorption 26
paths to the root