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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of Notch signaling pathway
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Accession:GO:0045747 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
Synonyms:exact_synonym: positive regulation of N signaling pathway;   positive regulation of N signalling pathway;   positive regulation of Notch signalling pathway;   up regulation of Notch signaling pathway;   upregulation of Notch signaling pathway
 narrow_synonym: activation of Notch signaling pathway;   stimulation of Notch signaling pathway


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positive regulation of Notch signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aak1 AP2 associated kinase 1 involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000107
(PMID:21464124)
PMID:21873635
UniProt
Ensembl
RGD
PMID:21464124, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 4:118,653,851...118,806,796
Ensembl chr 4:118,655,728...118,795,774
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (MGI:3639830|PMID:11073877) RGD PMID:11073877 MGI:3639830 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Bmp2k BMP-2 inducible kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:14,126,086...14,226,823
Ensembl chr14:14,129,725...14,192,048
JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:12050162), (PMID:20139355)
UniProt
RGD
PMID:12050162 PMID:20139355 GO_REF:0000024 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Cntn6 contactin 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5609887|PMID:25074942)
Ensembl
RGD
PMID:25074942 GO_REF:0000107 MGI:5609887 NCBI chr 4:136,512,201...136,904,355
Ensembl chr 4:136,512,201...136,904,355
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IDA
IEA
GO_REF:0000024
(MGI:3029032|PMID:10958687), (MGI:3847069|PMID:19144989), (MGI:3848562|PMID:19389377), (MGI:5296438|PMID:21915337), (MGI:5688841|PMID:18676613), (MGI:5689216|PMID:26114479)
(MGI:3575230|PMID:15574878)
PMID:22658936
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10958687 PMID:15574878 PMID:18676613 PMID:19144989 PMID:19389377 PMID:21915337 PMID:26114479, PMID:22658936 GO_REF:0000024 GO_REF:0000107 MGI:3029032 MGI:3575230 MGI:3847069 MGI:3848562 MGI:5296438 MGI:5688841 MGI:5689216, RGD:10402035 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO (MGI:5689216|PMID:26114479) RGD PMID:26114479 MGI:5689216 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Enho energy homeostasis associated involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5609887|PMID:25074942)
RGD PMID:25074942, PMID:21873635 MGI:5609887, RGD:13792537 NCBI chr 5:58,018,039...58,019,836
Ensembl chr 5:58,018,039...58,019,836
JBrowse link
G Epn2 epsin 2 involved_in ISO
IEA
(PMID:28717225)
GO_REF:0000107
RGD
Ensembl
PMID:28717225 GO_REF:0000107 NCBI chr10:47,795,496...47,857,373
Ensembl chr10:47,795,524...47,857,326
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO (MGI:4950299|PMID:21385765) RGD PMID:21385765 MGI:4950299 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:103302 (MGI:3612905|PMID:16324690) RGD PMID:16324690 MGI:3612905 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Gsx2 GS homeobox 2 acts_upstream_of_or_within ISO (MGI:5487482|PMID:23042297) RGD PMID:23042297 MGI:5487482 NCBI chr14:35,650,985...35,652,709
Ensembl chr14:35,650,985...35,652,709
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3625195|PMID:12208538)
Ensembl
RGD
PMID:12208538 GO_REF:0000107 MGI:3625195 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (MGI:3625195|PMID:12208538) RGD PMID:12208538 MGI:3625195 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA
(PMID:25731159)
(MGI:5629863|PMID:25731159)
GO_REF:0000107
RGD
Ensembl
PMID:25731159 GO_REF:0000107 MGI:5629863 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:43,348,927...43,363,633
Ensembl chr 6:43,348,958...43,363,335
JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3029032|PMID:10958687)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10958687 GO_REF:0000024 GO_REF:0000107 MGI:3029032 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3029032|PMID:10958687)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10958687 GO_REF:0000024 GO_REF:0000107 MGI:3029032 NCBI chr 6:137,711,144...137,733,331
Ensembl chr 6:137,711,155...137,733,026
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:15302600 RGD:2292509 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (MGI:3575230|PMID:15574878) RGD PMID:15574878 MGI:3575230 NCBI chr12:16,117,767...16,126,211
Ensembl chr12:16,118,634...16,126,953
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (MGI:3575230|PMID:15574878) RGD PMID:15574878 MGI:3575230 NCBI chr 7:119,978,981...119,996,824
Ensembl chr 7:119,978,983...119,996,824
JBrowse link
G Nepro nucleolus and neural progenitor protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4411921|PMID:19906856)
RGD PMID:19906856, PMID:21873635 MGI:4411921, RGD:13792537 NCBI chr11:60,919,477...60,931,642
Ensembl chr11:60,919,453...60,931,794
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (MGI:4946442|PMID:21156799) RGD PMID:21156799 MGI:4946442 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (MGI:5581550|PMID:24667410) RGD PMID:24667410 MGI:5581550 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:23388056) RGD PMID:23388056 NCBI chr 2:173,966,701...174,012,730
Ensembl chr 2:173,967,080...174,012,676
JBrowse link
G Poglut1 protein O-glucosyltransferase 1 involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:5700252|PMID:26496195)
GO_REF:0000107
PMID:21873635
(PMID:27807076)
UniProt
RGD
Ensembl
PMID:26496195 PMID:27807076, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5700252, RGD:13792537 NCBI chr11:64,761,493...64,788,210
Ensembl chr11:64,761,146...64,788,208
JBrowse link
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3575230|PMID:15574878)
Ensembl
RGD
PMID:15574878 GO_REF:0000107 MGI:3575230 NCBI chr10:109,963,726...109,966,821
Ensembl chr10:109,943,817...109,966,826
JBrowse link
G Slc35c2 solute carrier family 35 member C2 acts_upstream_of_or_within ISO (MGI:4849897|PMID:20837470) RGD PMID:20837470 MGI:4849897 NCBI chr 3:161,801,194...161,812,318
Ensembl chr 3:161,801,197...161,812,291
JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (MGI:3640906|PMID:16631155) RGD PMID:16631155 MGI:3640906 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:25731159)
(MGI:5629863|PMID:25731159)
RGD PMID:25731159 MGI:5629863 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5284803|PMID:15156153)
UniProt
RGD
PMID:15156153 GO_REF:0000024 MGI:5284803 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IEA
(PMID:25217442)
GO_REF:0000107
RGD
Ensembl
PMID:25217442 GO_REF:0000107 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tp63 tumor protein p63 involved_in
acts_upstream_of_or_within
ISO (PMID:11641404)
MGI:5140823 (MGI:5310685|PMID:22274697)
RGD PMID:11641404 PMID:22274697 MGI:5310685 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tspan14 tetraspanin 14 involved_in ISO (PMID:23091066) RGD PMID:23091066 NCBI chr16:17,538,855...17,595,960
Ensembl chr16:17,538,855...17,595,960
JBrowse link
G Tspan5 tetraspanin 5 involved_in ISO (PMID:23091066) RGD PMID:23091066 NCBI chr 2:244,058,186...244,224,059
Ensembl chr 2:244,058,186...244,224,058
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO (PMID:25731159)
(MGI:5629863|PMID:25731159)
RGD PMID:25731159 MGI:5629863 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (MGI:5790022|PMID:26522984) RGD PMID:26522984 MGI:5790022 NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614
JBrowse link
positive regulation of Notch signaling pathway involved in heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      signal transduction 6881
        positive regulation of signal transduction 1597
          positive regulation of Notch signaling pathway 42
            positive regulation of Notch signaling pathway involved in heart induction 4
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              Notch signaling pathway 177
                regulation of Notch signaling pathway 86
                  positive regulation of Notch signaling pathway 42
                    positive regulation of Notch signaling pathway involved in heart induction 4
paths to the root