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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of DNA replication
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Accession:GO:0045740 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: up regulation of DNA replication;   upregulation of DNA replication
 narrow_synonym: activation of DNA replication;   stimulation of DNA replication

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positive regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in ISO (PMID:23277426) UniProt PMID:23277426 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Atf1 activating transcription factor 1 ISO RGD PMID:11925444 RGD:625519 NCBI chrNW_004955547:1,263,288...1,299,525
Ensembl chrNW_004955547:1,257,944...1,299,519 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain 1A involved_in ISO (PMID:12434153)
(MGI:6810810|PMID:12434153)		 ComplexPortal PMID:12434153 MGI:6810810 NCBI chrNW_004955409:26,136,961...26,231,960
Ensembl chrNW_004955409:26,149,665...26,231,180 		JBrowse link
G Brpf3 bromodomain and PHD finger containing 3 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chrNW_004955437:3,951,160...3,985,133
Ensembl chrNW_004955437:3,951,160...3,985,338 		JBrowse link
G Cacybp calcyclin binding protein ISO mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chrNW_004955406:14,823,509...14,840,127 JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955452:2,255,940...2,299,042
Ensembl chrNW_004955452:2,255,117...2,299,042 		JBrowse link
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:19821535 RGD:2316313 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:26842564) UniProt PMID:26842564 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102 		JBrowse link
G Cst3 cystatin C ISO In rat mesangial cells RGD PMID:1540157 RGD:2306501 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (MGI:4441245|PMID:19119139) UniProt PMID:19119139 MGI:4441245 NCBI chrNW_004955467:8,673,069...8,700,730
Ensembl chrNW_004955467:8,673,128...8,702,165 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:24990949) UniProt PMID:24990949 NCBI chrNW_004955406:21,697,813...21,743,551
Ensembl chrNW_004955406:21,697,813...21,745,011 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:18995831) UniProt PMID:18995831 NCBI chrNW_004955425:20,664,412...20,705,070
Ensembl chrNW_004955425:20,661,727...20,702,754 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:17115032) UniProt PMID:17115032 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Ereg epiregulin involved_in ISO (PMID:10681561), (PMID:9337852)
(MGI:1333540|PMID:9337852), (MGI:3687425|PMID:7706296)
PMID:9990076		 UniProt PMID:7706296 PMID:9337852 PMID:9990076 PMID:10681561 MGI:1333540 MGI:3687425 RGD:632743 NCBI chrNW_004955474:612,440...627,606
Ensembl chrNW_004955474:612,440...627,606 		JBrowse link
G Faf1 Fas associated factor 1 involved_in ISO (PMID:26842564) UniProt PMID:26842564 NCBI chrNW_004955464:8,037,344...8,477,798
Ensembl chrNW_004955464:8,036,955...8,479,249 		JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:12165851) UniProt PMID:12165851 NCBI chrNW_004955458:5,181,761...5,193,500
Ensembl chrNW_004955458:5,185,225...5,193,196 		JBrowse link
G Gli2 GLI family zinc finger 2 involved_in ISO (PMID:12165851) UniProt PMID:12165851 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333 		JBrowse link
G Il6 interleukin 6 ISO RGD PMID:15828022 RGD:2306943 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ins insulin involved_in ISO (PMID:7513704) BHF-UCL PMID:7513704 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chrNW_004955451:11,770,201...11,802,992
Ensembl chrNW_004955451:11,770,201...11,802,992 		JBrowse link
G Kctd13 potassium channel tetramerization domain containing 13 ISO RGD PMID:15726626 RGD:1357162 NCBI chrNW_004955493:7,039,027...7,055,798
Ensembl chrNW_004955493:7,038,698...7,055,798 		JBrowse link
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004955487:6,139,188...6,207,316
Ensembl chrNW_004955487:6,138,926...6,210,012 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955467:5,188,036...5,295,570
Ensembl chrNW_004955467:5,187,356...5,307,692 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:1332507 RGD:2316794 NCBI chrNW_004955439:20,956,862...20,957,839
Ensembl chrNW_004955439:20,956,862...20,957,839 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17427161 RGD:2317489 NCBI chrNW_004955432:22,440,671...22,519,592
Ensembl chrNW_004955432:22,440,637...22,517,647 		JBrowse link
G Npm1 nucleophosmin 1 ISO RGD PMID:11481036 RGD:1600909 NCBI chrNW_004955408:24,151,070...24,218,783 JBrowse link
G Npm2 nucleophosmin/nucleoplasmin 2 ISO lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chrNW_004955403:45,517,426...45,539,216
Ensembl chrNW_004955403:45,517,396...45,539,274 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:24939902) UniProt PMID:24939902 NCBI chrNW_004955415:15,744,601...15,748,910
Ensembl chrNW_004955415:15,744,601...15,749,673 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:12084843 RGD:1581760 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:9487126 RGD:2293350 NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (PMID:12434153)
(MGI:6810810|PMID:12434153)		 ComplexPortal PMID:12434153 MGI:6810810 NCBI chrNW_004955471:12,206,462...12,240,219
Ensembl chrNW_004955471:12,203,318...12,237,333 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO (MGI:4441245|PMID:19119139) UniProt PMID:19119139 MGI:4441245 NCBI chrNW_004955485:6,748,682...6,784,119
Ensembl chrNW_004955485:6,748,234...6,784,762 		JBrowse link
G Tnfaip1 TNF alpha induced protein 1 ISO RGD PMID:15726626 RGD:1357162 NCBI chrNW_004955481:4,786,015...4,799,376
Ensembl chrNW_004955481:4,786,015...4,799,274 		JBrowse link
G Ucn urocortin ISO RGD PMID:11087261 RGD:1642796 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641 		JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chrNW_004955405:16,148,640...16,187,272
Ensembl chrNW_004955405:16,148,480...16,186,282 		JBrowse link
G E2f8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chrNW_004955476:197,699...215,227
Ensembl chrNW_004955476:197,630...213,441 		JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102 		JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (PMID:20215406) MGI PMID:20215406 NCBI chrNW_004955458:3,555,603...3,561,063
Ensembl chrNW_004955458:3,555,603...3,562,120 		JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (PMID:15585571)
(PMID:20215406)		 MGI PMID:15585571 PMID:20215406 NCBI chrNW_004955570:716,124...732,551
Ensembl chrNW_004955570:707,637...732,980 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in ISO (PMID:29719607) UniProt PMID:29719607 NCBI chrNW_004955570:1,200,461...1,203,566
Ensembl chrNW_004955570:1,200,996...1,203,566 		JBrowse link
G Mtnap1 mitochondrial nucleoid associated protein 1 involved_in ISO (MGI:7564184|PMID:37676315) UniProt PMID:37676315 MGI:7564184 NCBI chrNW_004955553:251,370...328,606
Ensembl chrNW_004955553:252,095...362,568 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO (PMID:31550240) UniProt PMID:31550240 NCBI chrNW_004955494:1,807,885...1,826,375
Ensembl chrNW_004955494:1,814,106...1,826,375 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:2161540) MGI PMID:2161540 NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chrNW_004955557:947,368...1,252,701
Ensembl chrNW_004955557:947,167...1,252,724 		JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chrNW_004955423:2,902,352...2,923,743
Ensembl chrNW_004955423:2,902,048...2,924,573 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) UniProt PMID:20237820 NCBI chrNW_004955416:7,870,521...8,020,862
Ensembl chrNW_004955416:7,870,258...7,961,812 		JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chrNW_004955495:7,810,145...7,834,908
Ensembl chrNW_004955495:7,811,804...7,833,918 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      positive regulation of metabolic process 3160
        positive regulation of macromolecule metabolic process 2866
          positive regulation of DNA metabolic process 261
            positive regulation of DNA replication 49
              positive regulation of DNA-templated DNA replication + 13
Path 2
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      organic substance metabolic process 7146
        organic cyclic compound metabolic process 4092
          nucleobase-containing compound metabolic process 3735
            nucleic acid metabolic process 3369
              DNA metabolic process 760
                DNA replication 224
                  regulation of DNA replication 114
                    positive regulation of DNA replication 49
                      positive regulation of DNA-templated DNA replication + 13
paths to the root