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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of DNA replication
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Accession:GO:0045740 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: up regulation of DNA replication;   upregulation of DNA replication
 narrow_synonym: activation of DNA replication;   stimulation of DNA replication



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positive regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in ISO (PMID:23277426) UniProt PMID:23277426 NCBI chr17:25,944,259...26,009,317
Ensembl chr17:25,436,195...25,496,242
JBrowse link
G ATF1 activating transcription factor 1 ISO RGD PMID:11925444 RGD:625519 NCBI chr12:37,930,383...37,988,476
Ensembl chr12:38,832,318...38,888,204
JBrowse link
G BCAR3 BCAR3 adaptor protein, NSP family member involved_in ISO (PMID:18722344) UniProt PMID:18722344 NCBI chr 1:96,230,498...96,508,028
Ensembl chr 1:94,960,966...95,080,565
JBrowse link
G BRPF3 bromodomain and PHD finger containing 3 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chr 6:35,755,305...35,791,304
Ensembl chr 6:36,959,709...36,989,933
JBrowse link
G CACYBP calcyclin binding protein ISO mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr 1:150,511,021...150,522,369
Ensembl chr 1:154,210,001...154,220,583
JBrowse link
G CDC42 cell division cycle 42 ISO RGD PMID:9487126 RGD:2293350 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CDK1 cyclin dependent kinase 1 ISO RGD PMID:19821535 RGD:2316313 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434
JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:26842564) UniProt PMID:26842564 NCBI chr16:69,516,728...69,522,419
Ensembl chr16:89,174,071...89,177,823
JBrowse link
G CST3 cystatin C ISO In rat mesangial cells RGD PMID:1540157 RGD:2306501 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in ISO (MGI:4441245|PMID:19119139) UniProt PMID:19119139 MGI:4441245 NCBI chr17:43,410,385...43,433,784
Ensembl chr17:48,142,864...48,165,537
JBrowse link
G DHX9 DExH-box helicase 9 involved_in ISO (PMID:24990949) UniProt PMID:24990949 NCBI chr 1:158,355,472...158,404,178
Ensembl chr 1:162,006,822...162,055,833
JBrowse link
G DNA2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:18995831) UniProt PMID:18995831 NCBI chr10:64,898,024...64,956,541
Ensembl chr10:67,207,261...67,264,257
JBrowse link
G EGF epidermal growth factor involved_in ISO (PMID:18722344) UniProt PMID:18722344 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO (PMID:17115032) UniProt PMID:17115032 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EREG epiregulin involved_in ISO (PMID:10681561), (PMID:9337852)
(MGI:1333540|PMID:9337852), (MGI:3687425|PMID:7706296)
PMID:9990076
UniProt PMID:7706296 PMID:9337852 PMID:9990076 PMID:10681561 MGI:1333540 MGI:3687425 RGD:632743 NCBI chr 4:49,806,505...49,827,961
Ensembl chr 4:55,641,014...55,660,568
JBrowse link
G FAF1 Fas associated factor 1 involved_in ISO (PMID:26842564) UniProt PMID:26842564 NCBI chr 1:49,679,198...50,207,129
Ensembl chr 1:51,188,540...51,606,904
JBrowse link
G GLI1 GLI family zinc finger 1 involved_in ISO (PMID:12165851) UniProt PMID:12165851 NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473
JBrowse link
G GLI2 GLI family zinc finger 2 involved_in ISO (PMID:12165851) UniProt PMID:12165851 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO RGD PMID:9487126 RGD:2293350 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G IL6 interleukin 6 ISO RGD PMID:15828022 RGD:2306943 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INS insulin involved_in ISO (PMID:7513704) BHF-UCL PMID:7513704 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:9487126 RGD:2293350 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chr17:43,875,921...43,916,352
Ensembl chr17:48,605,488...48,645,784
JBrowse link
G KCTD13 potassium channel tetramerization domain containing 13 ISO RGD PMID:15726626 RGD:1357162
G LPIN1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:9487126 RGD:2293350 NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:9487126 RGD:2293350 NCBI chr10:45,806,748...45,936,362 JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:1332507 RGD:2316794 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17427161 RGD:2317489 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:11481036 RGD:1600909 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 ISO lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr 8:21,268,873...21,281,684
Ensembl chr 8:18,208,934...18,221,577
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:12084843 RGD:1581760 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G RAC1 Rac family small GTPase 1 ISO RGD PMID:9487126 RGD:2293350 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G STN1 STN1 subunit of CST complex involved_in ISO (MGI:4441245|PMID:19119139) UniProt PMID:19119139 MGI:4441245 NCBI chr10:100,456,589...100,518,010
Ensembl chr10:103,942,422...103,977,847
JBrowse link
G TNFAIP1 TNF alpha induced protein 1 ISO RGD PMID:15726626 RGD:1357162 NCBI chr17:28,427,448...28,438,826
Ensembl chr17:28,929,788...28,941,278
JBrowse link
G UCN urocortin ISO RGD PMID:11087261 RGD:1642796 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2F7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chr12:74,540,049...74,582,561
Ensembl chr12:77,388,950...77,433,262
JBrowse link
G E2F8 E2F transcription factor 8 involved_in ISO (MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264) UniProt PMID:23064264 PMID:23064266 MGI:5449497 MGI:5449498 NCBI chr11:19,250,045...19,267,629
Ensembl chr11:19,162,837...19,179,744
JBrowse link
positive regulation of DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chr16:69,516,728...69,522,419
Ensembl chr16:89,174,071...89,177,823
JBrowse link
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (MGI:4439421|PMID:20215406) MGI PMID:20215406 MGI:4439421 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945
JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (MGI:3513706|PMID:15585571)
(MGI:4439421|PMID:20215406)
MGI PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 9:99,282,821...99,325,404
Ensembl chr 9:127,956,915...127,982,449
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SSBP1 single stranded DNA binding protein 1 involved_in ISO (PMID:31550240) UniProt PMID:31550240 NCBI chr 7:133,670,085...133,682,228
Ensembl chr 7:146,139,837...146,151,495
JBrowse link
G STOML2 stomatin like 2 involved_in ISO (PMID:21746876) UniProt PMID:21746876 NCBI chr 9:34,950,387...34,953,707
Ensembl chr 9:35,755,790...35,759,091
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) MGI PMID:2161540 MGI:79015 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chr  X:66,682,968...66,969,421
Ensembl chr  X:76,795,574...77,083,486
JBrowse link
G CDC7 cell division cycle 7 involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chr 1:94,158,628...94,183,537
Ensembl chr 1:92,902,631...92,927,203
JBrowse link
G DBF4B DBF4 zinc finger B involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chr17:12,571,265...12,616,105
Ensembl chr17:12,744,297...12,790,089
JBrowse link
G INO80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) UniProt PMID:20237820 NCBI chr15:19,920,980...20,058,117
Ensembl chr15:38,170,982...38,307,311
JBrowse link
G WIZ WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chr19:14,952,948...14,981,300
Ensembl chr19:15,940,642...15,965,859
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12659
    metabolic process 7935
      biosynthetic process 4044
        positive regulation of biosynthetic process 1804
          positive regulation of macromolecule biosynthetic process 1650
            positive regulation of DNA replication 49
              positive regulation of DNA-dependent DNA replication + 13
Path 2
Term Annotations click to browse term
  biological_process 12659
    metabolic process 7935
      organic substance metabolic process 7648
        macromolecule metabolic process 6554
          macromolecule biosynthetic process 3273
            cellular macromolecule biosynthetic process 3230
              DNA replication 193
                regulation of DNA replication 106
                  positive regulation of DNA replication 49
                    positive regulation of DNA-dependent DNA replication + 13
paths to the root