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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of DNA replication
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Accession:GO:0045740 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: up regulation of DNA replication;   upregulation of DNA replication
 narrow_synonym: activation of DNA replication;   stimulation of DNA replication


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positive regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO (PMID:23277426) RGD PMID:23277426 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Atf1 activating transcription factor 1 IMP RGD PMID:11925444 RGD:625519 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A involved_in ISO
IBA		 (PMID:12434153)
PMID:21873635
(MGI:6810810|PMID:12434153)		 RGD PMID:12434153 PMID:21873635 MGI:6810810, RGD:13792537 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO
ISS		 (PMID:18722344)
GO_REF:0000024		 RGD
UniProt		 PMID:18722344 GO_REF:0000024 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Brpf3 bromodomain and PHD finger containing, 3 involved_in ISO (PMID:26620551) RGD PMID:26620551 NCBI chr20:6,864,684...6,902,760
Ensembl chr20:6,865,985...6,902,690 		JBrowse link
G Cacybp calcyclin binding protein IDA mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Cdc42 cell division cycle 42 IMP RGD PMID:9487126 RGD:2293350 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 IMP RGD PMID:19821535 RGD:2316313 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:26842564) RGD PMID:26842564 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Cst3 cystatin C IDA In rat mesangial cells RGD PMID:1540157 RGD:2306501 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in IBA
ISO		 PMID:21873635
(MGI:4441245|PMID:19119139)		 RGD PMID:19119139 PMID:21873635 MGI:4441245, RGD:13792537 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:24990949) RGD PMID:24990949 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Egf epidermal growth factor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18722344)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18722344 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:17115032) RGD PMID:17115032 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ereg epiregulin involved_in ISS
ISO
IDA		 GO_REF:0000024
(MGI:1333540|PMID:9337852), (MGI:3687425|PMID:7706296)
PMID:9990076
(PMID:10681561), (PMID:9337852)		 UniProt
RGD		 PMID:7706296 PMID:9337852 PMID:10681561 PMID:9990076 GO_REF:0000024 MGI:1333540 MGI:3687425, RGD:632743 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Faf1 Fas associated factor 1 involved_in ISO
IEA		 (PMID:26842564)
GO_REF:0000107		 RGD
Ensembl		 PMID:26842564 GO_REF:0000107 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977 		JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:12165851) RGD PMID:12165851 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 involved_in ISO (PMID:12165851) RGD PMID:12165851 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Hras HRas proto-oncogene, GTPase IMP RGD PMID:9487126 RGD:2293350 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Il6 interleukin 6 IMP RGD PMID:15828022 RGD:2306943 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:7513704) RGD PMID:7513704 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:9487126 RGD:2293350 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO
ISS		 (PMID:26620551)
GO_REF:0000024		 RGD
UniProt		 PMID:26620551 GO_REF:0000024 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567 		JBrowse link
G Kctd13 potassium channel tetramerization domain containing 13 IDA RGD PMID:15726626 RGD:1357162 NCBI chr 1:181,534,534...181,552,843
Ensembl chr 1:181,534,515...181,552,881 		JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IMP RGD PMID:9487126 RGD:2293350 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IMP RGD PMID:9487126 RGD:2293350 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IMP RGD PMID:17427161 RGD:2317489 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Npm1 nucleophosmin 1 IDA RGD PMID:11481036 RGD:1600909 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Npm2 nucleophosmin/nucleoplasmin 2 involved_in IDA
IBA		 lesser effect than Npm1
PMID:21873635		 RGD
GO_Central		 PMID:11481036 PMID:21873635 RGD:1600909, RGD:13792537 NCBI chr15:45,722,494...45,729,246
Ensembl chr15:45,722,400...45,729,726 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO
ISS		 (PMID:24939902)
GO_REF:0000024
GO_REF:0000114		 RGD
UniProt
ComplexPortal		 PMID:24939902 GO_REF:0000024 GO_REF:0000114 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IMP RGD PMID:12084843 RGD:1581760 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Rac1 Rac family small GTPase 1 IMP RGD PMID:9487126 RGD:2293350 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,158...25,717,558
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (PMID:12434153)
(MGI:6810810|PMID:12434153)		 RGD PMID:12434153 MGI:6810810 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4441245|PMID:19119139)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19119139 GO_REF:0000024 GO_REF:0000107 MGI:4441245 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Tnfaip1 TNF alpha induced protein 1 IDA RGD PMID:15726626 RGD:1357162 NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466 		JBrowse link
G Ucn urocortin IDA RGD PMID:11087261 RGD:1642796 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO
ISS
IEA		 (MGI:5449497|PMID:23064266)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:23064266 GO_REF:0000024 GO_REF:0000107 MGI:5449497 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5449497|PMID:23064266), (MGI:5449498|PMID:23064264)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23064264 PMID:23064266 GO_REF:0000024 GO_REF:0000107 MGI:5449497 MGI:5449498 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1920234 (MGI:4439421|PMID:20215406)
GO_REF:0000107		 RGD
Ensembl		 PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:104772 (MGI:3513706|PMID:15585571), (MGI:4439421|PMID:20215406) RGD PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 3:15,658,479...15,675,716
Ensembl chr 3:15,658,539...15,673,762 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in ISO (PMID:29719607) RGD PMID:29719607 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO
ISS
IEA		 (PMID:31550240)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:31550240 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) RGD PMID:2161540 MGI:79015 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5568153|PMID:24651726)		 UniProt
Ensembl
RGD		 PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Dbf4 DBF4 zinc finger involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbf4b DBF4 zinc finger B involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr10:87,713,805...87,719,197 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) RGD PMID:23545495 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      positive regulation of metabolic process 4010
        positive regulation of macromolecule metabolic process 3497
          positive regulation of DNA metabolic process 305
            positive regulation of DNA replication 53
              positive regulation of DNA-templated DNA replication + 14
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        cellular aromatic compound metabolic process 3078
          nucleobase-containing compound metabolic process 2826
            nucleic acid metabolic process 2315
              DNA metabolic process 1001
                DNA replication 275
                  regulation of DNA replication 134
                    positive regulation of DNA replication 53
                      positive regulation of DNA-templated DNA replication + 14
paths to the root