Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cyclin-dependent protein serine/threonine kinase activity
go back to main search page
Accession:GO:0045736 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.



show annotations for term's descendants           Sort by:
 
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:8521819)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:8521819 GO_REF:0000024 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:2178778 (MGI:2677082|PMID:12970760) RGD PMID:12970760 MGI:2677082 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 involved_in ISO
IBA
ISS
(PMID:11882646)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:11882646 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IDA RGD PMID:10721722 RGD:632478 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IDA RGD PMID:10721722 RGD:632478 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2183076|PMID:12130539)
PMID:21873635
RGD PMID:12130539 PMID:21873635 MGI:2183076, RGD:13792537 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
(PMID:28666995)
(MGI:2183076|PMID:12130539)
PMID:21873635
RGD PMID:12130539 PMID:28666995 PMID:22584582 PMID:21873635 MGI:2183076, RGD:10045364, RGD:13792537 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in
ISO (MGI:2183076|PMID:12130539)
(PMID:8259215)
(PMID:7739547)
RGD PMID:7739547 PMID:8259215 PMID:12130539 MGI:2183076 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (MGI:72259|PMID:7739547) RGD PMID:7739547 MGI:72259 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of_or_within ISO (MGI:5317390|PMID:21652635) RGD PMID:21652635 MGI:5317390 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:14580347)
GO_REF:0000024
RGD
UniProt
PMID:14580347 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Hexim2 HEXIM P-TEFb complex subunit 2 involved_in IBA
ISO
PMID:21873635
(PMID:15713662)
RGD PMID:15713662 PMID:21873635 RGD:13792537 NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775
JBrowse link
G Hhex hematopoietically expressed homeobox involved_in ISO (PMID:12554669) RGD PMID:12554669 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5292392 (MGI:5286822|PMID:21540187)
(PMID:21540187)
RGD PMID:21540187 PMID:21873635 MGI:5286822, RGD:13792537 NCBI chr10:55,401,982...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (MGI:4410401|PMID:19773423) RGD PMID:19773423 MGI:4410401 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:9988268) RGD PMID:9988268 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) RGD PMID:12853976 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
JBrowse link
G Men1 menin 1 involved_in ISO (PMID:15640349) RGD PMID:15640349 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mir103a1 microRNA 103a-1 involved_in ISO (PMID:27343180) RGD PMID:27343180 NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497
JBrowse link
G Mir103a2 microRNA 103a-2 involved_in ISO (PMID:27343180) RGD PMID:27343180 NCBI chr 3:118,510,194...118,510,279
Ensembl chr 3:118,510,194...118,510,279
JBrowse link
G Mir711 microRNA 711 involved_in ISO (PMID:26735582) RGD PMID:26735582 NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042
JBrowse link
G Myocd myocardin involved_in ISO
IEA
(PMID:18451334)
GO_REF:0000107
RGD
Ensembl
PMID:18451334 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in ISO (PMID:19210544) RGD PMID:19210544 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21041660)
Ensembl
RGD
PMID:21041660 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4943408|PMID:15962316) RGD PMID:15962316 MGI:4943408 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Wee2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (MGI:4948986|PMID:21454751) RGD PMID:21454751 MGI:4948986 NCBI chr 4:69,239,043...69,261,576
Ensembl chr 4:69,239,299...69,261,093
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      cell cycle 1634
        negative regulation of cell cycle 397
          negative regulation of cyclin-dependent protein serine/threonine kinase activity 31
Path 2
Term Annotations click to browse term
  biological_process 20099
    biological regulation 13928
      regulation of biological process 13160
        negative regulation of biological process 5864
          negative regulation of cellular process 5121
            negative regulation of cellular metabolic process 2421
              negative regulation of phosphorus metabolic process 484
                negative regulation of phosphate metabolic process 484
                  negative regulation of phosphorylation 419
                    negative regulation of kinase activity 248
                      negative regulation of protein kinase activity 225
                        negative regulation of cyclin-dependent protein kinase activity 31
                          negative regulation of cyclin-dependent protein serine/threonine kinase activity 31
paths to the root