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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cyclin-dependent protein serine/threonine kinase activity
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Accession:GO:0045736 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.


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negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:8521819)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:8521819 GO_REF:0000024 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:2178778 (MGI:2677082|PMID:12970760) RGD PMID:12970760 MGI:2677082 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 involved_in ISO
IBA
ISS		 (PMID:11882646)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:11882646 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IDA RGD PMID:10721722 RGD:632478 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IDA RGD PMID:10721722 RGD:632478 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2183076|PMID:12130539)
PMID:21873635		 RGD PMID:12130539 PMID:21873635 MGI:2183076, RGD:13792537 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 (PMID:28666995)
(MGI:2183076|PMID:12130539)
PMID:21873635		 RGD PMID:12130539 PMID:28666995 PMID:22584582 PMID:21873635 MGI:2183076, RGD:10045364, RGD:13792537 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO (MGI:2183076|PMID:12130539)
(PMID:8259215)
(PMID:7739547)		 RGD PMID:7739547 PMID:8259215 PMID:12130539 MGI:2183076 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (MGI:72259|PMID:7739547) RGD PMID:7739547 MGI:72259 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of_or_within ISO (MGI:5317390|PMID:21652635) RGD PMID:21652635 MGI:5317390 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:14580347)
GO_REF:0000024		 RGD
UniProt		 PMID:14580347 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hexim2 HEXIM P-TEFb complex subunit 2 involved_in IBA
ISO		 PMID:21873635
(PMID:15713662)		 RGD PMID:15713662 PMID:21873635 RGD:13792537 NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775 		JBrowse link
G Hhex hematopoietically expressed homeobox involved_in ISO (PMID:12554669) RGD PMID:12554669 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5292392 (MGI:5286822|PMID:21540187)
(PMID:21540187)		 RGD PMID:21540187 PMID:21873635 MGI:5286822, RGD:13792537 NCBI chr10:55,401,982...55,414,364
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (MGI:4410401|PMID:19773423) RGD PMID:19773423 MGI:4410401 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:9988268) RGD PMID:9988268 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) RGD PMID:12853976 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G Men1 menin 1 involved_in ISO (PMID:15640349) RGD PMID:15640349 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir103a1 microRNA 103a-1 involved_in ISO (PMID:27343180) RGD PMID:27343180 NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497 		JBrowse link
G Mir103a2 microRNA 103a-2 involved_in ISO (PMID:27343180) RGD PMID:27343180 NCBI chr 3:118,510,194...118,510,279
Ensembl chr 3:118,510,194...118,510,279 		JBrowse link
G Mir711 microRNA 711 involved_in ISO (PMID:26735582) RGD PMID:26735582 NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042 		JBrowse link
G Myocd myocardin involved_in ISO
IEA		 (PMID:18451334)
GO_REF:0000107		 RGD
Ensembl		 PMID:18451334 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in ISO (PMID:19210544) RGD PMID:19210544 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21041660)		 Ensembl
RGD		 PMID:21041660 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4943408|PMID:15962316) RGD PMID:15962316 MGI:4943408 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Wee2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (MGI:4948986|PMID:21454751) RGD PMID:21454751 MGI:4948986 NCBI chr 4:69,239,043...69,261,576
Ensembl chr 4:69,239,299...69,261,093 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      cell cycle 1634
        negative regulation of cell cycle 397
          negative regulation of cyclin-dependent protein serine/threonine kinase activity 31
Path 2
Term Annotations click to browse term
  biological_process 20099
    biological regulation 13928
      regulation of biological process 13160
        negative regulation of biological process 5864
          negative regulation of cellular process 5121
            negative regulation of cellular metabolic process 2421
              negative regulation of phosphorus metabolic process 484
                negative regulation of phosphate metabolic process 484
                  negative regulation of phosphorylation 419
                    negative regulation of kinase activity 248
                      negative regulation of protein kinase activity 225
                        negative regulation of cyclin-dependent protein kinase activity 31
                          negative regulation of cyclin-dependent protein serine/threonine kinase activity 31
paths to the root