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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein catabolic process
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Accession:GO:0045732 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Synonyms:exact_synonym: positive regulation of cellular protein breakdown;   positive regulation of cellular protein catabolic process;   positive regulation of cellular protein catabolism;   positive regulation of cellular protein degradation;   positive regulation of protein breakdown;   positive regulation of protein catabolism;   positive regulation of protein degradation;   up regulation of cellular protein breakdown;   up regulation of cellular protein catabolic process;   up regulation of cellular protein catabolism;   up regulation of cellular protein degradation;   up regulation of protein catabolic process;   upregulation of cellular protein breakdown;   upregulation of cellular protein catabolic process;   upregulation of cellular protein catabolism;   upregulation of cellular protein degradation;   upregulation of protein catabolic process
 narrow_synonym: activation of cellular protein breakdown;   activation of cellular protein catabolic process;   activation of cellular protein catabolism;   activation of cellular protein degradation;   activation of protein catabolic process;   positive regulation of cyclin breakdown;   positive regulation of cyclin catabolic process;   positive regulation of cyclin catabolism;   positive regulation of cyclin degradation;   positive regulation of degradation of cyclin;   stimulation of protein catabolic process
 alt_id: GO:1903364;   GO:2000600


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positive regulation of protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amer1 APC membrane recruitment protein 1 involved_in ISO (PMID:17510365) RGD PMID:17510365 NCBI chr  X:60,300,595...60,316,480
Ensembl chr  X:60,295,751...60,316,440 		JBrowse link
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
UniProtKB:O43255|UniProtKB:P41221 (PMID:12952940)
(MGI:3618985|PMID:16478791)		 Ensembl
RGD		 PMID:12952940 PMID:16478791 PMID:21873635 GO_REF:0000107 MGI:3618985, RGD:13792537 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,014,485...30,037,808
Ensembl chr  X:29,992,416...30,037,807 		JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109 		JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:17148442)		 RGD PMID:17148442 PMID:21873635 RGD:13792537 NCBI chr  X:29,956,576...30,001,436
Ensembl chr  X:29,956,576...30,001,105 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase IMP RGD PMID:16874114 RGD:2301238 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atg7 autophagy related 7 involved_in ISO
IEA
ISS		 (PMID:20543840)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20543840 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Axin1 axin 1 involved_in ISO (PMID:9601641) RGD PMID:9601641 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G C4bpa complement component 4 binding protein, alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:22333221)		 Ensembl
RGD		 PMID:22333221 GO_REF:0000107 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA		 (PMID:22333221)
GO_REF:0000107		 RGD
Ensembl		 PMID:22333221 GO_REF:0000107 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180572 (MGI:3038342|PMID:14973438)		 Ensembl
RGD		 PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B acts_upstream_of_or_within ISO (PMID:19056892) RGD PMID:19056892 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO
ISS		 (PMID:20625391)
GO_REF:0000024		 RGD
UniProt		 PMID:20625391 GO_REF:0000024 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Cul4a cullin 4A involved_in ISO (PMID:11027288), (PMID:20870715) RGD PMID:11027288 PMID:20870715 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cul4b cullin 4B acts_upstream_of_or_within ISO (MGI:3820198|PMID:18602923) RGD PMID:18602923 MGI:3820198 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453088|PMID:19948740)		 UniProt
RGD		 PMID:19948740 GO_REF:0000024 MGI:4453088 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16446366)
(PMID:16446366), (PMID:18936100)		 RGD PMID:16446366 PMID:18936100 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dcaf1 DDB1 and CUL4 associated factor 1 involved_in ISO (PMID:23063525) RGD PMID:23063525 NCBI chr 8:107,466,229...107,540,633
Ensembl chr 8:107,474,312...107,540,627 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:14739464), (PMID:16949367)		 Ensembl
RGD		 PMID:14739464 PMID:16949367 GO_REF:0000107 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:16949367) RGD PMID:16949367 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 involved_in ISO
IEA		 (PMID:11595184)
GO_REF:0000107		 RGD
Ensembl		 PMID:11595184 GO_REF:0000107 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751 		JBrowse link
G Ezr ezrin involved_in ISO
IEA		 UniProtKB:P26038|UniProtKB:P35241 (PMID:21148287)
GO_REF:0000107		 RGD
Ensembl		 PMID:21148287 GO_REF:0000107 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Faf1 Fas associated factor 1 involved_in ISO
IEA		 (PMID:26842564)
GO_REF:0000107		 RGD
Ensembl		 PMID:26842564 GO_REF:0000107 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 acts_upstream_of_or_within ISO MGI:5295289 (MGI:5292406|PMID:21907140) RGD PMID:21907140 MGI:5292406 NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383 		JBrowse link
G Fbxo11 F-box protein 11 IMP RGD PMID:32988261 RGD:152176655 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISO
ISS		 (PMID:20543840)
GO_REF:0000024		 RGD
UniProt		 PMID:20543840 GO_REF:0000024 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gga1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 acts_upstream_of_or_within ISO MGI:2384159 (MGI:5432614|PMID:22836275) RGD PMID:22836275 MGI:5432614 NCBI chr 7:110,436,071...110,451,790
Ensembl chr 7:110,435,062...110,451,789 		JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 acts_upstream_of_or_within ISO MGI:2146207 (MGI:5432614|PMID:22836275) RGD PMID:22836275 MGI:5432614 NCBI chr10:100,825,427...100,843,422
Ensembl chr10:100,825,426...100,844,462 		JBrowse link
G Gja1 gap junction protein, alpha 1 IDA RGD PMID:12952975 RGD:1582696 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
(MGI:3790551|PMID:18477453)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18477453 GO_REF:0000024 GO_REF:0000107 MGI:3790551 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:17686886 RGD:10045647 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (MGI:5293184|PMID:21700773) RGD PMID:21700773 MGI:5293184 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO UniProtKB:Q9UNE7 (PMID:18292230) RGD PMID:18292230 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:1856404 (MGI:3038342|PMID:14973438) RGD PMID:14973438 MGI:3038342 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (MGI:4460850|PMID:20018880) RGD PMID:20018880 MGI:4460850 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 IMP Human Estrogen Receptor alpha RGD PMID:12917323 RGD:2304230 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Msn moesin involved_in ISO
IEA		 UniProtKB:P15311|UniProtKB:P35241 (PMID:21148287)
GO_REF:0000107		 RGD
Ensembl		 PMID:21148287 GO_REF:0000107 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) RGD PMID:19520913 MGI:3849777 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3695433 (MGI:3694584|PMID:17137798)
GO_REF:0000107		 RGD
Ensembl		 PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO UniProtKB:O43464 (PMID:17297443) RGD PMID:17297443 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2176314|PMID:11748237)
GO_REF:0000107
(PMID:14973438)		 RGD
Ensembl		 PMID:11748237 PMID:14973438 GO_REF:0000107 MGI:2176314 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase IMP RGD PMID:18174164 RGD:6893331 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 involved_in ISO (PMID:15687260) RGD PMID:15687260 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase involved_in IEA
ISO		 GO_REF:0000107
(PMID:22045810)		 Ensembl
RGD		 PMID:22045810 GO_REF:0000107 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(MGI:5574513|PMID:24967154)
(PMID:17900240)
GO_REF:0000107
PMID:21873635		 UniProt
RGD
Ensembl		 PMID:17900240 PMID:24967154 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5574513, RGD:13792537 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310 		JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5574513|PMID:24967154)		 RGD PMID:24967154 PMID:21873635 MGI:5574513, RGD:13792537 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 involved_in IBA
ISO
IEA		 PMID:21873635
(MGI:5574513|PMID:24967154)
GO_REF:0000107		 RGD
Ensembl		 PMID:24967154 PMID:21873635 GO_REF:0000107 MGI:5574513, RGD:13792537 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399 		JBrowse link
G Plk2 polo-like kinase 2 involved_in ISO
IEA		 (PMID:23983262)
GO_REF:0000107		 RGD
Ensembl		 PMID:23983262 GO_REF:0000107 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha involved_in ISO (PMID:15687260) RGD PMID:15687260 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:22072966) RGD PMID:22072966 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO (PMID:11027288), (PMID:16482215), (PMID:27626656) RGD PMID:11027288 PMID:16482215 PMID:27626656 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rdx radixin involved_in ISO UniProtKB:P15311|UniProtKB:P26038 (PMID:21148287) RGD PMID:21148287 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISO
ISS		 (PMID:18953687), (PMID:22624035) RGD PMID:18953687 PMID:22624035 PMID:18953687 PMID:22624035 RGD:8554435, RGD:8553377 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Rhbdd3 rhomboid domain containing 3 acts_upstream_of_or_within ISO (MGI:5492204|PMID:23610400) RGD PMID:23610400 MGI:5492204 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175 		JBrowse link
G Rilp Rab interacting lysosomal protein involved_in ISO (PMID:17959629) RGD PMID:17959629 NCBI chr10:60,355,276...60,358,434
Ensembl chr10:60,355,278...60,358,781 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:27353365) RGD PMID:27353365 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein involved_in ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 2:185,500,029...185,520,811
Ensembl chr 2:185,500,004...185,522,026 		JBrowse link
G Sgsm3 small G protein signaling modulator 3 involved_in ISO
IEA		 (MGI:3689782|PMID:15709751)
GO_REF:0000107		 RGD
Ensembl		 PMID:15709751 GO_REF:0000107 MGI:3689782 NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108 		JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in ISO (PMID:17959629) RGD PMID:17959629 NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734 		JBrowse link
G Snx1 sorting nexin 1 IMP RGD PMID:11110793 RGD:68866 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:24523320) RGD PMID:24523320 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:4887291|PMID:20802155) RGD PMID:20802155 MGI:4887291 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3839710|PMID:19047045) RGD PMID:19047045 MGI:3839710 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Stx5 syntaxin 5 involved_in ISO (PMID:21242315) RGD PMID:21242315 NCBI chr 1:205,637,401...205,653,563
Ensembl chr 1:205,637,413...205,653,563 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase acts_upstream_of_or_within ISO (PMID:23275542) RGD PMID:23275542 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:18632959) RGD PMID:18632959 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:21127049)
(MGI:3839729|PMID:18952128)		 RGD PMID:18952128 PMID:21127049 MGI:3839729 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfsf12 TNF superfamily member 12 acts_upstream_of_or_within ISO (PMID:17389268) RGD PMID:17389268 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:3836317|PMID:19269368)
(MGI:3610252|PMID:16243356)		 BHF-UCL
RGD		 PMID:16243356 PMID:19269368 GO_REF:0000024 MGI:3610252 MGI:3836317 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Ubr3 ubiquitin protein ligase E3 component n-recognin 3 IMP RGD PMID:32988261 RGD:152176655 NCBI chr 3:54,649,803...54,806,779
Ensembl chr 3:54,649,992...54,806,247 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:11483959), (PMID:18775313) RGD PMID:11483959 PMID:18775313 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Vgll4 vestigial-like family member 4 involved_in ISO (MGI:6120600|PMID:27720608) RGD PMID:27720608 MGI:6120600 NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471 		JBrowse link
G Vip vasoactive intestinal peptide involved_in ISO
IBA
IEA
IDA		 (PMID:9603988)
PMID:21873635
GO_REF:0000107
(MGI:5318038|PMID:9603988)		 RGD
Ensembl		 PMID:9603988 PMID:21873635 PMID:9603988 GO_REF:0000107 MGI:5318038, RGD:13792537, RGD:8554017 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:21148287) RGD PMID:21148287 NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568 		JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in ISO
IEA		 (PMID:11916981)
GO_REF:0000107		 RGD
Ensembl		 PMID:11916981 GO_REF:0000107 NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO UniProtKB:P37840 (PMID:25533483) RGD PMID:25533483 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in		 ISO
IEA		 UniProtKB:O43255|UniProtKB:P25054 (PMID:12952940)
GO_REF:0000107		 RGD
Ensembl		 PMID:12952940 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
positive regulation of chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISO (PMID:27344333) RGD PMID:27344333 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:24089527)
GO_REF:0000107		 RGD
Ensembl		 PMID:24089527 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:18307982), (PMID:22045699) RGD PMID:18307982 PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in ISO
IEA		 (PMID:23246001)
GO_REF:0000107		 RGD
Ensembl		 PMID:23246001 GO_REF:0000107 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18307982)		 Ensembl
UniProt
RGD		 PMID:18307982 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISO
IEA		 (PMID:17000876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17000876 GO_REF:0000107 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISO
IEA		 (PMID:24424410)
GO_REF:0000107		 RGD
Ensembl		 PMID:24424410 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
IEA
ISS		 (PMID:27485036)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27485036 GO_REF:0000024 GO_REF:0000107 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO
IBA		 (PMID:27485036)
PMID:21873635		 RGD PMID:27485036 PMID:21873635 RGD:13792537 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778 		JBrowse link
G Rnft2 ring finger protein, transmembrane 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:38,329,217...38,387,303
Ensembl chr12:38,329,269...38,387,290 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26265139)		 UniProt
RGD		 PMID:26265139 GO_REF:0000024 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Tmem259 transmembrane protein 259 involved_in IBA
ISO		 PMID:21873635
(MGI:5648655|PMID:25977983)		 RGD PMID:25977983 PMID:21873635 MGI:5648655, RGD:13792537 NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932 		JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29932915)		 Ensembl
RGD		 PMID:29932915 GO_REF:0000107 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:4999711|PMID:19911006) RGD PMID:19911006 MGI:4999711 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
positive regulation of low-density lipoprotein particle receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:21810484)
GO_REF:0000107		 RGD
Ensembl		 PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA		 (PMID:15950758)
GO_REF:0000107		 RGD
Ensembl		 PMID:15950758 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
positive regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IEA		 (MGI:5902678|PMID:22383525)
GO_REF:0000107		 RGD
Ensembl		 PMID:22383525 GO_REF:0000107 MGI:5902678 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO
IEA		 (PMID:23152628)
GO_REF:0000107		 RGD
Ensembl		 PMID:23152628 GO_REF:0000107 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISO (PMID:9228033) RGD PMID:9228033 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 involved_in ISO
IEA		 (PMID:29573664)
GO_REF:0000107		 RGD
Ensembl		 PMID:29573664 GO_REF:0000107 NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794 		JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in IBA
ISO		 PMID:21873635
(MGI:3040545|PMID:14761956)
(PMID:15220135), (PMID:17548643)		 RGD PMID:14761956 PMID:15220135 PMID:17548643 PMID:21873635 MGI:3040545, RGD:13792537 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (MGI:1326990|PMID:9857183) RGD PMID:9857183 MGI:1326990 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA		 UniProtKB:P05067-PRO_0000000092 (PMID:15950758), (PMID:25015123)
GO_REF:0000107		 RGD
Ensembl		 PMID:15950758 PMID:25015123 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P02649 (PMID:25015123) RGD PMID:25015123 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5447609|PMID:17720976)
(PMID:17720976)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17720976 GO_REF:0000024 GO_REF:0000107 MGI:5447609 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Nrdc nardilysin convertase involved_in ISO
ISS
IEA		 (PMID:18355445)
(MGI:4414693|PMID:19935654)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18355445 PMID:19935654 GO_REF:0000024 GO_REF:0000107 MGI:4414693 NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595 		JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 involved_in ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within ISO (MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:5702499 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Sh3d19 SH3 domain containing 19 involved_in ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 2:171,356,244...171,516,042
Ensembl chr 2:171,356,251...171,515,561 		JBrowse link
G Snx33 sorting nexin 33 involved_in ISO (PMID:18353773), (PMID:18419754) RGD PMID:18353773 PMID:18419754 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538 		JBrowse link
G Snx9 sorting nexin 9 involved_in ISO (PMID:18353773) RGD PMID:18353773 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO
IBA		 (PMID:22480688)
PMID:21873635		 RGD PMID:22480688 PMID:21873635 RGD:13792537 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
ISS		 (PMID:20080667)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20080667 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:19416853)		 RGD PMID:19416853 PMID:21873635 RGD:13792537 NCBI chr18:27,309,711...27,319,106
Ensembl chr18:27,309,718...27,319,032 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:23858059)
(MGI:5543313|PMID:23858059)		 RGD PMID:23858059 MGI:5543313 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5770038|PMID:24709664)		 UniProt
RGD		 PMID:24709664 GO_REF:0000024 MGI:5770038 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:22180649) RGD PMID:22180649 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO		 GO_REF:0000024
(PMID:16300740)		 UniProt
RGD		 PMID:16300740 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Osbpl7 oxysterol binding protein-like 7 involved_in ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Rnf40 ring finger protein 40 IDA RGD PMID:12121982 RGD:633892 NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in ISO (PMID:21603654) RGD PMID:21603654 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6150565|PMID:29518356) RGD PMID:29518356 MGI:6150565 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) RGD PMID:21317886 MGI:4946566 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3589701|PMID:15937334)
GO_REF:0000107
(PMID:23512198)		 RGD
Ensembl		 PMID:15937334 PMID:23512198 GO_REF:0000107 MGI:3589701 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2446434|MGI:3587769|MGI:3691571 (MGI:5465208|PMID:23152632) RGD PMID:23152632 MGI:5465208 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Aurka aurora kinase A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697244|PMID:17060449)
GO_REF:0000107		 RGD
Ensembl		 PMID:17060449 GO_REF:0000107 MGI:3697244 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (MGI:3628833|PMID:16601693)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:16601693 PMID:21873635 GO_REF:0000107 MGI:3628833, RGD:13792537 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bag2 BAG cochaperone 2 NOT|involved_in ISO UniProtKB:P10636 (MGI:6148635|PMID:19228967) RGD PMID:19228967 MGI:6148635 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO UniProtKB:Q99496 (PMID:22302990) RGD PMID:22302990 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:25974097) RGD PMID:25974097 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (MGI:5310666|PMID:22285184) RGD PMID:22285184 MGI:5310666 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Clu clusterin involved_in ISO
IBA
IEA
ISS		 (PMID:20068069)
PMID:21873635
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20068069 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cop1 COP1, E3 ubiquitin ligase involved_in ISO (PMID:19805145) RGD PMID:19805145 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISO
IEA		 (PMID:11955436), (PMID:19364825)
GO_REF:0000107		 RGD
Ensembl		 PMID:11955436 PMID:19364825 GO_REF:0000107 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:3849793|PMID:19414593)		 UniProt
RGD		 PMID:19414593 PMID:21873635 GO_REF:0000024 MGI:3849793, RGD:13792537 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO
IBA		 (MGI:3849793|PMID:19414593)
PMID:21873635		 RGD PMID:19414593 PMID:21873635 MGI:3849793, RGD:13792537 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12805222)		 Ensembl
RGD		 PMID:12805222 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dda1 DET1 and DDB1 associated 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:23675531) RGD PMID:23675531 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IBA
ISO		 PMID:21873635
UniProtKB:Q8NHY2 (PMID:14739464)		 RGD PMID:14739464 PMID:21873635 RGD:13792537 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IBA
ISO		 PMID:21873635
(PMID:15936278)		 RGD PMID:15936278 PMID:21873635 RGD:13792537 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Fbxo22 F-box protein 22 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3840749|PMID:19319192)
PMID:21873635		 RGD PMID:19319192 PMID:21873635 MGI:3840749, RGD:13792537 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Fbxw8 F-box and WD repeat domain containing 8 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6148490|PMID:29153991)		 Ensembl
RGD		 PMID:29153991 GO_REF:0000107 MGI:6148490 NCBI chr12:38,426,466...38,517,076
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:25684205)		 UniProt
RGD		 PMID:25684205 GO_REF:0000024 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (MGI:5501380|PMID:23707074) RGD PMID:23707074 MGI:5501380 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2387010 (MGI:3695876|PMID:17189825) RGD PMID:17189825 MGI:3695876 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IEA		 (PMID:25897075)
GO_REF:0000107		 RGD
Ensembl		 PMID:25897075 GO_REF:0000107 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1924375|MGI:3039600 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:22660580), (PMID:25897075)
GO_REF:0000107		 RGD
Ensembl		 PMID:19364825 PMID:22660580 PMID:25897075 GO_REF:0000107 MGI:5437589 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in IBA
ISO		 PMID:21873635
(PMID:24613385)		 RGD PMID:24613385 PMID:21873635 RGD:13792537 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 involved_in ISO (PMID:16831871) RGD PMID:16831871 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861437|MGI:3039600 (MGI:5437589|PMID:22660580)		 Ensembl
RGD		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) RGD PMID:25940086 MGI:5700633 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (MGI:4454597|PMID:20457918) RGD PMID:20457918 MGI:4454597 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) RGD PMID:29153991 MGI:6148490 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6148490|PMID:29153991)		 Ensembl
RGD		 PMID:29153991 GO_REF:0000107 MGI:6148490 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:11278372) RGD PMID:11278372 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:20177058) RGD PMID:20177058 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 RGD PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 involved_in ISO (PMID:16707496) RGD PMID:16707496 NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO
ISS		 (PMID:27588481)
GO_REF:0000024		 RGD
UniProt		 PMID:27588481 GO_REF:0000024 NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 involved_in ISO (MGI:5487503|PMID:22406621) RGD PMID:22406621 MGI:5487503 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Plk1 polo-like kinase 1 involved_in ISO
ISS
IEA		 (PMID:19473992)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19473992 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA		 (PMID:17030191)
GO_REF:0000107		 RGD
Ensembl		 PMID:17030191 GO_REF:0000107 NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:5543313|PMID:23858059)		 Ensembl
RGD		 PMID:23858059 PMID:21873635 GO_REF:0000107 MGI:5543313, RGD:13792537 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:4887523 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS		 (PMID:16023600)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16023600 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19785988)		 UniProt
RGD		 PMID:19785988 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein involved_in ISO (PMID:26296656) RGD PMID:26296656 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO UniProtKB:Q7L5Y6 (PMID:14739464) RGD PMID:14739464 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Rnf14 ring finger protein 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685 		JBrowse link
G Rnf144a ring finger protein 144A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Rnf144b ring finger protein 144B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)		 RGD PMID:18363970 PMID:23926250 PMID:21873635 MGI:3819024 MGI:5505713, RGD:13792537 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222 		JBrowse link
G Rnf19b ring finger protein 19B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf217 ring finger protein 217 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:26,016,668...26,108,736
Ensembl chr 1:26,015,728...26,108,736 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in IMP
IBA
ISO		 PMID:22128169
PMID:21873635
(PMID:22128169)		 RGD PMID:22128169 PMID:22128169 PMID:21873635 RGD:13673844, RGD:13792537 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24681946)
GO_REF:0000107
(MGI:5574427|PMID:24681946)		 UniProt
RGD
Ensembl		 PMID:24681946 GO_REF:0000024 GO_REF:0000107 MGI:5574427 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27457971) RGD PMID:27457971 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:11146632) RGD PMID:11146632 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 involved_in ISO (PMID:18408734) RGD PMID:18408734 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) RGD PMID:15053879 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in IBA
ISO		 PMID:21873635
(MGI:4457446|PMID:20410507)		 RGD PMID:20410507 PMID:21873635 MGI:4457446, RGD:13792537 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib2 tribbles pseudokinase 2 involved_in ISO (MGI:4457446|PMID:20410507) RGD PMID:20410507 MGI:4457446 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:19098288) RGD PMID:19098288 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:9452483) RGD PMID:9452483 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Zer1 zyg-11 related, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 3:13,369,688...13,397,524
Ensembl chr 3:13,369,688...13,397,420 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO MGI:3664591 (MGI:3663213|PMID:16973439) RGD PMID:16973439 MGI:3663213 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677 		JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) RGD PMID:31273098 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20889502)		 UniProt
RGD		 PMID:20889502 GO_REF:0000024 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
positive regulation of protein catabolic process in the vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISO
IEA		 (PMID:25635054)
GO_REF:0000107		 RGD
Ensembl		 PMID:25635054 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      catabolic process 2673
        positive regulation of catabolic process 625
          positive regulation of protein catabolic process 212
            positive regulation of chaperone-mediated autophagy 1
            positive regulation of elastin catabolic process 0
            positive regulation of low-density lipoprotein particle receptor catabolic process 3
            positive regulation of membrane protein ectodomain proteolysis 16
            positive regulation of proteasomal protein catabolic process + 117
            positive regulation of protein catabolic process in the vacuole + 5
            positive regulation of proteolysis associated with antigen processing and presentation 0
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      organic substance metabolic process 10908
        macromolecule metabolic process 9179
          macromolecule catabolic process 1478
            protein catabolic process 1022
              regulation of protein catabolic process 377
                positive regulation of protein catabolic process 212
                  positive regulation of chaperone-mediated autophagy 1
                  positive regulation of elastin catabolic process 0
                  positive regulation of low-density lipoprotein particle receptor catabolic process 3
                  positive regulation of membrane protein ectodomain proteolysis 16
                  positive regulation of proteasomal protein catabolic process + 117
                  positive regulation of protein catabolic process in the vacuole + 5
                  positive regulation of proteolysis associated with antigen processing and presentation 0
paths to the root