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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of epidermis development
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Accession:GO:0045682 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of epidermis development.
Synonyms:exact_synonym: regulation of epidermal development
 related_synonym: regulation of hypodermis development


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regulation of epidermis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NAB1 NGFI-A binding protein 1 acts_upstream_of_or_within ISO (PMID:16136673) MGI PMID:16136673 NCBI chr2B:77,949,948...77,994,888
Ensembl chr2B:195,868,102...195,911,497 		JBrowse link
G NAB2 NGFI-A binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16136673) Ensembl
MGI		 PMID:16136673 GO_REF:0000107 Ensembl chr12:32,085,031...32,091,498 JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 involved_in ISO (PMID:16862176) HGNC-UCL PMID:16862176 NCBI chr17:45,255,982...45,261,541 JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:44,265,017...44,308,897 JBrowse link
G TFAP2C transcription factor AP-2 gamma acts_upstream_of_or_within ISO (PMID:18353300) MGI PMID:18353300 NCBI chr20:52,966,907...52,981,024
Ensembl chr20:54,255,489...54,265,432 		JBrowse link
negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726 		JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,813,288...7,819,418
Ensembl chr12:7,972,907...7,979,815 		JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16495313) Ensembl
MGI		 PMID:16495313 GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:17117437) MGI PMID:17117437 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11023859), (PMID:11425898)
(PMID:21300049)		 Ensembl
MGI		 PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HES5 hes family bHLH transcription factor 5 acts_upstream_of_or_within ISO (PMID:11425898)
(PMID:21300049)		 MGI PMID:11425898 PMID:21300049 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXTL3 exostosin like glycosyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:27,983,700...28,035,879
Ensembl chr 8:25,174,414...25,233,599 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726 		JBrowse link
G HOXA7 homeobox A7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11435435) MGI
Ensembl		 PMID:11435435 GO_REF:0000107 NCBI chr 7:27,799,317...27,802,492
Ensembl chr 7:27,396,898...27,402,142 		JBrowse link
G LOC100991621 regenerating islet-derived protein 3-alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:79,243,526...79,246,273
Ensembl chr2A:80,807,308...80,810,056 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:19769717) MGI PMID:19769717 NCBI chr 5:170,063,137...170,070,226
Ensembl chr 5:176,967,902...176,976,609 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486 		JBrowse link
G REG3G regenerating family member 3 gamma involved_in ISO (MGI:5488867|PMID:22727489), (PMID:22727489) UniProt PMID:22727489 MGI:5488867 NCBI chr2A:79,116,083...79,118,886
Ensembl chr2A:80,680,615...80,683,748 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 involved_in ISO (PMID:24440982) UniProt PMID:24440982 NCBI chr20:39,795,659...39,801,864
Ensembl chr20:40,888,560...40,891,853 		JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22274697) Ensembl
MGI		 PMID:22274697 GO_REF:0000107 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104 		JBrowse link
positive regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G KDF1 keratinocyte differentiation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,210,572...26,221,991
Ensembl chr 1:27,267,106...27,277,684 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453 		JBrowse link
G PTCH2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 1:44,125,693...44,147,462
Ensembl chr 1:45,490,789...45,513,055 		JBrowse link
G SFN stratifin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,126,212...26,127,761
Ensembl chr 1:27,182,834...27,183,580 		JBrowse link
G SFRP4 secreted frizzled related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,542,105...38,553,008
Ensembl chr 7:38,764,146...38,774,264 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,576,770...45,601,839
Ensembl chr19:54,146,574...54,192,407 		JBrowse link
positive regulation of epidermis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT10 keratin 10 involved_in ISO (MGI:6107675|PMID:26603179) UniProt PMID:26603179 MGI:6107675 NCBI chr17:16,461,624...16,466,136
Ensembl chr17:16,686,898...16,690,415 		JBrowse link
G KRT2 keratin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:36,111,978...36,119,684
Ensembl chr12:36,889,619...36,896,813 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta ISO RGD PMID:19675577 RGD:2324879 NCBI chr 6:34,903,798...34,987,208
Ensembl chr 6:36,003,988...36,081,132 		JBrowse link
G TMEM79 transmembrane protein 79 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,625,864...131,635,370
Ensembl chr 1:135,455,766...135,465,426 		JBrowse link
positive regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11023859), (PMID:19154718) Ensembl
MGI		 PMID:11023859 PMID:19154718 GO_REF:0000107 NCBI chr 4:86,188,534...86,191,301
Ensembl chr 4:96,863,762...96,864,832 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:12417662) MGI PMID:12417662 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G ETV4 ETS variant transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,850,823...13,869,347
Ensembl chr17:14,099,160...14,116,186 		JBrowse link
G FOXC1 forkhead box C1 involved_in ISO (PMID:27907090) UniProt PMID:27907090 NCBI chr 6:1,429,051...1,433,180 JBrowse link
G LOC100971127 arachidonate 15-lipoxygenase type B involved_in ISO (MGI:3784332|PMID:10965849) UniProt PMID:10965849 MGI:3784332 NCBI chr17:43,609,146...43,619,713
Ensembl chr17:48,340,777...48,350,808 		JBrowse link
G LOC100974647 core histone macro-H2A.2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,526,013...66,585,568
Ensembl chr10:69,077,456...69,114,194 		JBrowse link
G LOC100974858 core histone macro-H2A.1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834 		JBrowse link
G MED1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549 		JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 involved_in ISO (PMID:16862176) HGNC-UCL PMID:16862176 NCBI chr17:45,255,982...45,261,541 JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17079689)
(PMID:16618808)		 Ensembl
MGI		 PMID:16618808 PMID:17079689 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,083,378...67,160,747
Ensembl chr11:70,307,847...70,384,425 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24735878) Ensembl
MGI		 PMID:24735878 GO_REF:0000107 NCBI chr20:17,983,277...18,019,441
Ensembl chr20:17,962,123...17,994,486 		JBrowse link
G PKP1 plakophilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,881,154...176,930,814
Ensembl chr 1:181,182,829...181,232,347 		JBrowse link
G PLAAT4 phospholipase A and acyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,889,014...58,898,757
Ensembl chr11:62,240,321...62,249,990 		JBrowse link
G PRKCH protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,882,022...42,151,305
Ensembl chr14:60,179,081...60,408,251 		JBrowse link
G TRIM16 tripartite motif containing 16 involved_in ISO (PMID:11919186) UniProt PMID:11919186 NCBI chr17:35,973,775...36,028,767 JBrowse link
G VDR vitamin D receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192 		JBrowse link
G ZBED2 zinc finger BED-type containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:108,739,338...108,741,826
Ensembl chr 3:115,664,606...115,665,262 		JBrowse link
regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KEAP1 kelch like ECH associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15087497) Ensembl
MGI		 PMID:15087497 GO_REF:0000107 NCBI chr19:10,037,544...10,055,091
Ensembl chr19:10,701,303...10,717,604 		JBrowse link
G KLF7 KLF transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:94,307,334...94,399,553
Ensembl chr2B:212,448,337...212,525,403 		JBrowse link
G MAFF MAF bZIP transcription factor F acts_upstream_of_or_within ISO (PMID:15087497) MGI PMID:15087497 NCBI chr22:19,114,929...19,129,901 JBrowse link
G MAFG MAF bZIP transcription factor G involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15087497) Ensembl
TreeGrafter
MGI		 PMID:15087497 GO_REF:0000107 GO_REF:0000118 NCBI chr17:76,323,874...76,333,300
Ensembl chr17:82,030,699...82,031,278 		JBrowse link
regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:21300049) MGI PMID:21300049 NCBI chr 8:76,286,433...76,290,507
Ensembl chr 8:77,913,761...77,921,201 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19154718) Ensembl
MGI		 PMID:19154718 GO_REF:0000107 NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056 		JBrowse link
G MYCL MYCL proto-oncogene, bHLH transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23022312) Ensembl
MGI		 PMID:23022312 GO_REF:0000107 NCBI chr 1:39,184,883...39,191,413
Ensembl chr 1:40,510,820...40,517,821 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (PMID:23022312) MGI PMID:23022312 NCBI chr2A:15,925,130...15,931,605 JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESRP1 epithelial splicing regulatory protein 1 involved_in ISO (MGI:5915403|PMID:29107558) UniProt PMID:29107558 MGI:5915403 NCBI chr 8:91,261,488...91,327,990
Ensembl chr 8:93,203,198...93,530,653 		JBrowse link
regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:102,194,286...102,401,175
Ensembl chr2B:220,668,957...220,873,566 		JBrowse link
G CD109 CD109 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22490868) Ensembl
MGI		 PMID:22490868 GO_REF:0000107 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G GRHL1 grainyhead like transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24586629) Ensembl
MGI		 PMID:24586629 GO_REF:0000107 NCBI chr2A:9,944,385...9,994,510
Ensembl chr2A:10,105,486...10,155,177 		JBrowse link
G KRT36 keratin 36 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,824,312...15,830,729
Ensembl chr17:16,041,753...16,048,162 		JBrowse link
G KRT84 keratin 84 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:36,376,965...36,384,798
Ensembl chr12:37,154,048...37,162,672 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986 		JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:44,265,017...44,308,897 JBrowse link
G TNK2 tyrosine kinase non receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:193,254,017...193,302,863 JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:36,505,056...36,507,693
Ensembl chr19:45,052,801...45,055,390 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16768
    developmental process 6614
      regulation of developmental process 2596
        regulation of epidermis development 68
          negative regulation of epidermis development + 15
          positive regulation of epidermis development + 31
          regulation of epidermal cell differentiation + 61
Path 2
Term Annotations click to browse term
  biological_process 16768
    developmental process 6614
      anatomical structure development 6217
        tissue development 2198
          epidermis development 384
            regulation of epidermis development 68
              negative regulation of epidermis development + 15
              positive regulation of epidermis development + 31
              regulation of epidermal cell differentiation + 61
paths to the root