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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of megakaryocyte differentiation
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Accession:GO:0045653 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
Synonyms:exact_synonym: down regulation of megakaryocyte differentiation;   downregulation of megakaryocyte differentiation
 narrow_synonym: inhibition of megakaryocyte differentiation

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negative regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cib1 calcium and integrin binding 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:15,963,863...15,967,458 JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3808108|PMID:16757682) MGI
Ensembl		 PMID:16757682 GO_REF:0000107 MGI:3808108 NCBI chrNW_004936640:1,882,297...1,917,210 JBrowse link
G LOC101957180 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:3,139,838...3,140,223 JBrowse link
G LOC101966143 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936580:173,731...175,254 JBrowse link
G LOC101967236 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:2,803,784...2,804,173 JBrowse link
G LOC101972420 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:2,019,007...2,019,428 JBrowse link
G LOC101972801 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:1,953,045...1,953,612 JBrowse link
G LOC101974797 histone H3.1 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:1,881,645...1,882,070 JBrowse link
G LOC101978127 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936587:2,702,038...2,704,472 JBrowse link
G LOC106145261 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chrNW_004936671:1,888,128...1,888,666 JBrowse link
G Myb MYB proto-oncogene, transcription factor involved_in ISO (PMID:25857263) BHF-UCL PMID:25857263 NCBI chrNW_004936560:2,797,943...2,828,813 JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,492,032...3,502,738 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    cellular process 13961
      negative regulation of cellular process 4413
        negative regulation of cell differentiation 673
          negative regulation of myeloid cell differentiation 85
            negative regulation of megakaryocyte differentiation 12
Path 2
Term Annotations click to browse term
  biological_process 14973
    developmental process 5969
      anatomical structure development 5591
        multicellular organism development 4819
          system development 4403
            immune system development 1008
              hematopoietic or lymphoid organ development 945
                hemopoiesis 898
                  myeloid cell differentiation 417
                    megakaryocyte differentiation 57
                      regulation of megakaryocyte differentiation 30
                        negative regulation of megakaryocyte differentiation 12
paths to the root