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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of megakaryocyte differentiation
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Accession:GO:0045653 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
Synonyms:exact_synonym: down regulation of megakaryocyte differentiation;   downregulation of megakaryocyte differentiation
 narrow_synonym: inhibition of megakaryocyte differentiation


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negative regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIB1 calcium and integrin binding 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 7:55,794,834...55,798,666
Ensembl chr 7:55,794,834...55,798,590 		JBrowse link
G GABPA GA binding protein transcription factor subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3808108|PMID:16757682) Ensembl
Ensembl
MGI		 PMID:16757682 GO_REF:0000107 MGI:3808108 NCBI chr13:189,289,513...189,327,501
Ensembl chr13:189,278,149...189,327,500 		JBrowse link
G LOC100158117 histone H4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:21,595,863...21,596,243 JBrowse link
G LOC100524373 platelet factor 4 involved_in ISO (PMID:2140694) UniProt PMID:2140694
G LOC110261477 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr 7:20,773,579...20,773,986 JBrowse link
G LOC110261673 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr 7:20,910,487...20,912,374
Ensembl chr 7:20,908,345...20,912,379 		JBrowse link
G LOC110261674 histone H4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr 7:21,224,973...21,225,379 JBrowse link
G MYB MYB proto-oncogene, transcription factor involved_in ISO (PMID:25857263) BHF-UCL PMID:25857263 NCBI chr 1:28,819,500...28,856,222
Ensembl chr 1:28,819,503...28,857,000 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:54,718,845...54,730,411
Ensembl chr 6:54,711,393...54,732,574 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17268
    cellular process 16297
      negative regulation of cellular process 4924
        negative regulation of cell differentiation 750
          negative regulation of myeloid cell differentiation 91
            negative regulation of megakaryocyte differentiation 9
Path 2
Term Annotations click to browse term
  biological_process 17268
    developmental process 6613
      anatomical structure development 6166
        multicellular organism development 5265
          system development 4811
            immune system development 1114
              hematopoietic or lymphoid organ development 1047
                hemopoiesis 998
                  myeloid cell differentiation 439
                    megakaryocyte differentiation 55
                      regulation of megakaryocyte differentiation 27
                        negative regulation of megakaryocyte differentiation 9
paths to the root