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Term:negative regulation of megakaryocyte differentiation
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Accession:GO:0045653 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
Synonyms:exact_synonym: down regulation of megakaryocyte differentiation;   downregulation of megakaryocyte differentiation
 narrow_synonym: inhibition of megakaryocyte differentiation

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negative regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cib1 calcium and integrin binding 1 (calmyrin) involved_in IMP (MGI:5314162|PMID:22128142) UniProt PMID:22128142 MGI:5314162 NCBI chr 7:79,876,904...79,882,553
Ensembl chr 7:79,876,895...79,882,561
JBrowse link
G Gabpa GA repeat binding protein, alpha acts_upstream_of_or_within IMP (MGI:3808108|PMID:16757682) MGI PMID:16757682 MGI:3808108 NCBI chr16:84,631,774...84,660,671
Ensembl chr16:84,631,813...84,660,667
JBrowse link
G H4c11 H4 clustered histone 11 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:21,919,204...21,919,626
Ensembl chr13:21,919,234...21,920,007
JBrowse link
G H4c12 H4 clustered histone 12 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:21,934,315...21,934,723
Ensembl chr13:21,934,364...21,934,675
JBrowse link
G H4c17 H4 clustered histone 17 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:21,995,916...21,996,320
Ensembl chr13:21,995,916...21,996,317
JBrowse link
G H4c18 H4 clustered histone 18 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:22,015,962...22,016,367
Ensembl chr13:22,015,937...22,016,366
JBrowse link
G H4c2 H4 clustered histone 2 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:23,940,920...23,941,369
Ensembl chr13:23,940,996...23,941,392
JBrowse link
G H4c3 H4 clustered histone 3 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:23,882,067...23,882,441
Ensembl chr13:23,881,618...23,882,437
JBrowse link
G H4c4 H4 clustered histone 4 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:23,765,551...23,765,952
Ensembl chr13:23,765,581...23,766,718
JBrowse link
G H4c8 H4 clustered histone 8 involved_in ISO (PMID:18474616) UniProt PMID:18474616 NCBI chr13:23,715,214...23,715,648
Ensembl chr13:23,715,220...23,715,689
JBrowse link
G H4f16 H4 histone 16 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:136,780,991...136,781,429
Ensembl chr 6:136,778,551...136,781,413
JBrowse link
G Mir3107 microRNA 3107 involved_in ISO (PMID:25857263) BHF-UCL PMID:25857263 NCBI chr 8:23,632,589...23,632,678
Ensembl chr 8:23,632,589...23,632,678
JBrowse link
G Mir486 microRNA 486 involved_in ISO (PMID:25857263) BHF-UCL PMID:25857263 NCBI chr 8:23,632,571...23,632,698
Ensembl chr 8:23,632,571...23,632,698
JBrowse link
G Myb myeloblastosis oncogene involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:2140694) UniProt PMID:2140694 NCBI chr 5:90,920,294...90,921,242
Ensembl chr 5:90,920,294...90,921,242
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28746
    cellular process 17701
      negative regulation of cellular process 5253
        negative regulation of cell differentiation 805
          negative regulation of myeloid cell differentiation 107
            negative regulation of megakaryocyte differentiation 16
Path 2
Term Annotations click to browse term
  biological_process 28746
    developmental process 7254
      anatomical structure development 6680
        multicellular organism development 5634
          system development 5123
            immune system development 1221
              hematopoietic or lymphoid organ development 1153
                hemopoiesis 1102
                  myeloid cell differentiation 487
                    megakaryocyte differentiation 63
                      regulation of megakaryocyte differentiation 33
                        negative regulation of megakaryocyte differentiation 16
paths to the root