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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of megakaryocyte differentiation
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Accession:GO:0045652 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.



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regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot4 CCR4-NOT transcription complex, subunit 4 involved_in ISO (PMID:26575292) RGD PMID:26575292 NCBI chr 4:63,712,770...63,814,355
Ensembl chr 4:63,712,770...63,814,360
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5780495|PMID:26391622)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26391622 GO_REF:0000024 GO_REF:0000107 MGI:5780495 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO MGI:2657016 (MGI:5293278|PMID:21665949) RGD PMID:21665949 MGI:5293278 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(MGI:3844189|PMID:19211936)
UniProt
RGD
PMID:19211936 GO_REF:0000024 MGI:3844189 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:26575292)
UniProt
RGD
PMID:26575292 GO_REF:0000024 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G Rbm15 RNA binding motif protein 15 involved_in ISO (PMID:26575292) RGD PMID:26575292 NCBI chr 2:194,945,717...194,954,523
Ensembl chr 2:194,945,974...194,954,703
JBrowse link
negative regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5314162|PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024 MGI:5314162 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha acts_upstream_of_or_within ISO MGI:3054951 (MGI:3808108|PMID:16757682) RGD PMID:16757682 MGI:3808108 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G H4c3 H4 clustered histone 3 involved_in ISO (PMID:18474616) RGD PMID:18474616
G H4f16 H4 histone 16 involved_in ISO (PMID:18474616) RGD PMID:18474616
G Hist1h4b histone cluster 1 H4 family member B involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
JBrowse link
G Hist1h4m histone cluster 1, H4m involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr17:42,698,054...42,698,365
Ensembl chr17:42,698,025...42,698,958
JBrowse link
G Hist2h4 histone cluster 2, H4 involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A involved_in ISO (PMID:18474616) RGD PMID:18474616
G LOC100912290 histone H4-like involved_in ISO (PMID:18474616) RGD PMID:18474616
G LOC102548682 histone H4-like involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr17:41,368,743...41,426,735 JBrowse link
G LOC102551184 histone H4-like involved_in ISO (PMID:18474616) RGD PMID:18474616 NCBI chr17:41,526,192...41,575,488 JBrowse link
G Pf4 platelet factor 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:2140694)
UniProt
RGD
PMID:2140694 GO_REF:0000024 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISO
ISS
(PMID:20442406)
GO_REF:0000024
RGD
UniProt
PMID:20442406 GO_REF:0000024 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 involved_in ISO (PMID:18474616) RGD PMID:18474616
positive regulation of megakaryocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faxdc2 fatty acid hydroxylase domain containing 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:27689744)
Ensembl
RGD
PMID:27689744 GO_REF:0000107 NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,246,868...42,271,871
JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:3769271|PMID:16254139) RGD PMID:16254139 MGI:3769271 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISO (PMID:19965638) RGD PMID:19965638 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (MGI:5284774|PMID:17707228) RGD PMID:17707228 MGI:5284774 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G LOC102555319 zinc finger protein 16-like involved_in ISO (PMID:16628192) RGD PMID:16628192 NCBI chr 7:108,650,694...108,670,246 JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog involved_in ISO
ISS
(PMID:24681962)
(MGI:6378013|PMID:24681962)
GO_REF:0000024
RGD
UniProt
PMID:24681962 GO_REF:0000024 MGI:6378013 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950
JBrowse link
G Pithd1 PITH domain containing 1 involved_in ISO (PMID:25134913)
(MGI:6378063|PMID:25134913)
RGD PMID:25134913 MGI:6378063 NCBI chr 5:148,205,995...148,216,511
Ensembl chr 5:148,205,998...148,217,080
JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (PMID:20953574) RGD PMID:20953574 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Rcor1 REST corepressor 1 involved_in ISO (MGI:5284774|PMID:17707228) RGD PMID:17707228 MGI:5284774 NCBI chr 6:130,069,606...130,146,164
Ensembl chr 6:130,069,392...130,146,153
JBrowse link
G Scin scinderin involved_in ISO (PMID:11568009) RGD PMID:11568009 NCBI chr 6:57,110,128...57,188,059
Ensembl chr 6:57,109,403...57,188,242
JBrowse link
G Tesc tescalcin involved_in ISO
ISS
(PMID:17717601)
GO_REF:0000024
RGD
UniProt
PMID:17717601 GO_REF:0000024 NCBI chr12:38,521,839...38,555,665
Ensembl chr12:38,521,861...38,555,824
JBrowse link
G Thpo thrombopoietin involved_in ISS
ISO
GO_REF:0000024
(MGI:5314162|PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024 MGI:5314162 Ensembl chr11:80,182,820...80,188,167 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    regulation of biological process 12866
      regulation of immune system process 1530
        regulation of hemopoiesis 412
          regulation of myeloid cell differentiation 228
            regulation of megakaryocyte differentiation 32
              negative regulation of megakaryocyte differentiation 14
              positive regulation of megakaryocyte differentiation 12
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            animal organ development 4130
              hematopoietic or lymphoid organ development 1038
                hemopoiesis 986
                  myeloid cell differentiation 443
                    megakaryocyte differentiation 60
                      regulation of megakaryocyte differentiation 32
                        negative regulation of megakaryocyte differentiation 14
                        positive regulation of megakaryocyte differentiation 12
paths to the root