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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macrophage differentiation
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Accession:GO:0045649 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of macrophage differentiation.



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negative regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:10961870)
GO_REF:0000024
RGD
UniProt
PMID:10961870 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G C1qc complement C1q C chain involved_in ISO
IEA
(PMID:10961870)
GO_REF:0000107
RGD
Ensembl
PMID:10961870 GO_REF:0000107 NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:3769271|PMID:16254139) RGD PMID:16254139 MGI:3769271 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3629372|PMID:16705167)
UniProt
RGD
PMID:16705167 GO_REF:0000024 MGI:3629372 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Thoc5 THO complex 5 acts_upstream_of_or_within ISO (MGI:1349551|PMID:10597251) RGD PMID:10597251 MGI:1349551 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
positive regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112) RGD PMID:10822112 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:1856333 (MGI:893319|PMID:9215625)
GO_REF:0000107
(PMID:2460758)
RGD
Ensembl
PMID:2460758 PMID:9215625 PMID:21873635 GO_REF:0000107 MGI:893319, RGD:13792537 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 TAS RGD PMID:14504066 RGD:727979 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 involved_in ISO (MGI:5448611|PMID:23001182) RGD PMID:23001182 MGI:5448611 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:24504023) RGD PMID:24504023 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:97874 (MGI:3525032|PMID:15616565) RGD PMID:15616565 MGI:3525032 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Il34 interleukin 34 involved_in ISO
IBA
IEA
(PMID:23409120)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:23409120 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000
JBrowse link
G Lif LIF, interleukin 6 family cytokine acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7957045)
GO_REF:0000107
RGD
Ensembl
PMID:7957045 GO_REF:0000107 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Prkca protein kinase C, alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:5306334|PMID:9508782)
UniProt
RGD
PMID:9508782 GO_REF:0000024 MGI:5306334 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:96397 (MGI:3525032|PMID:15616565)
Ensembl
RGD
PMID:15616565 GO_REF:0000107 MGI:3525032 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) RGD PMID:17047155 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25749876 RGD:11537353 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) RGD PMID:23515163 MGI:5488531 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    regulation of biological process 12866
      regulation of cellular process 12336
        regulation of cell differentiation 1719
          regulation of leukocyte differentiation 324
            regulation of myeloid leukocyte differentiation 135
              regulation of macrophage differentiation 23
                negative regulation of macrophage differentiation + 6
                positive regulation of macrophage differentiation + 17
                regulation of microglia differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            immune system development 1105
              hematopoietic or lymphoid organ development 1038
                hemopoiesis 986
                  regulation of hemopoiesis 412
                    regulation of myeloid cell differentiation 228
                      regulation of myeloid leukocyte differentiation 135
                        regulation of macrophage differentiation 23
                          negative regulation of macrophage differentiation + 6
                          positive regulation of macrophage differentiation + 17
                          regulation of microglia differentiation + 1
paths to the root