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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of T-helper 2 cell differentiation
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Accession:GO:0045630 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of T-helper 2 cell differentiation;   upregulation of T-helper 2 cell differentiation
 narrow_synonym: activation of T-helper 2 cell differentiation;   stimulation of T-helper 2 cell differentiation
 related_synonym: positive regulation of T-helper 2 cell development


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positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA
ISO
GO_REF:0000107
(MGI:3608083|PMID:12829194)
Ensembl
RGD
PMID:12829194 GO_REF:0000107 MGI:3608083 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:2450484 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO
GO_REF:0000024
(MGI:3584076|PMID:15987782)
UniProt
RGD
PMID:15987782 GO_REF:0000024 MGI:3584076 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO (PMID:18416830) RGD PMID:18416830 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) RGD PMID:18354165 MGI:4943387 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    immune system process 2881
      immune response 1885
        type 2 immune response 37
          positive regulation of type 2 immune response 17
            positive regulation of T-helper 2 cell differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 19633
    developmental process 6782
      anatomical structure development 6259
        multicellular organism development 5740
          system development 5283
            immune system development 1089
              hematopoietic or lymphoid organ development 1023
                hemopoiesis 971
                  leukocyte differentiation 606
                    mononuclear cell differentiation 472
                      lymphocyte differentiation 419
                        T cell differentiation 295
                          T cell differentiation involved in immune response 79
                            alpha-beta T cell differentiation involved in immune response 71
                              CD4-positive, alpha-beta T cell differentiation involved in immune response 70
                                T-helper cell differentiation 68
                                  regulation of T-helper cell differentiation 40
                                    positive regulation of T-helper cell differentiation 19
                                      positive regulation of T-helper 2 cell differentiation 7
paths to the root