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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of T-helper 1 cell differentiation
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Accession:GO:0045625 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: regulation of T-helper 1 cell development


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regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936501:11,972,715...11,978,152
Ensembl chrNW_004936501:11,973,385...11,976,583
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:567,462...569,195
Ensembl chrNW_004936794:568,567...569,139
JBrowse link
G Il4r interleukin 4 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16424184) Ensembl
MGI
PMID:16424184 GO_REF:0000107 NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chrNW_004936524:2,765,271...2,767,259
Ensembl chrNW_004936524:2,765,267...2,767,385
JBrowse link
G Hlx H2.0 like homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16424184) Ensembl
MGI
PMID:16424184 GO_REF:0000107 NCBI chrNW_004936650:1,416,825...1,422,595
Ensembl chrNW_004936650:1,416,812...1,422,588
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11894097) Ensembl
MGI
PMID:11894097 GO_REF:0000107 NCBI chrNW_004936544:3,606,925...3,653,248
Ensembl chrNW_004936544:3,606,879...3,655,532
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,531,002...5,588,022
Ensembl chrNW_004936508:5,531,002...5,587,549
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    immune system process 2193
      immune response 1383
        regulation of immune response 804
          regulation of T-helper cell differentiation 38
            regulation of T-helper 1 cell differentiation 10
              negative regulation of T-helper 1 cell differentiation 4
              positive regulation of T-helper 1 cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 15871
    cellular process 15001
      cellular developmental process 4251
        cell differentiation 4250
          cell development 3049
            hemopoiesis 956
              leukocyte differentiation 607
                mononuclear cell differentiation 491
                  lymphocyte differentiation 402
                    T cell differentiation 299
                      T cell differentiation involved in immune response 80
                        alpha-beta T cell differentiation involved in immune response 73
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 72
                            T-helper cell differentiation 70
                              T-helper 1 cell differentiation 23
                                regulation of T-helper 1 cell differentiation 10
                                  negative regulation of T-helper 1 cell differentiation 4
                                  positive regulation of T-helper 1 cell differentiation 5
paths to the root