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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of T-helper cell differentiation
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Accession:GO:0045624 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of T-helper cell differentiation;   upregulation of T-helper cell differentiation
 narrow_synonym: activation of T-helper cell differentiation;   stimulation of T-helper cell differentiation
 related_synonym: positive regulation of T-helper cell development


show annotations for term's descendants           Sort by:
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24645804) Ensembl
MGI		 PMID:24645804 GO_REF:0000107 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097) Ensembl
MGI		 PMID:11894097 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927 		JBrowse link
G MIR326 microRNA mir-326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr21:23,240,463...23,240,553
Ensembl chr21:23,240,463...23,240,553 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (MGI:6106706|PMID:28262505) UniProt PMID:28262505 MGI:6106706 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    immune system process 2491
      immune effector process 650
        positive regulation of immune effector process 275
          positive regulation of T-helper cell differentiation 21
            positive regulation of T-helper 1 cell differentiation 5
            positive regulation of T-helper 17 cell differentiation + 9
            positive regulation of T-helper 2 cell differentiation 7
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular developmental process 4609
        cell differentiation 4608
          cell development 3263
            hemopoiesis 1054
              leukocyte differentiation 674
                mononuclear cell differentiation 552
                  lymphocyte differentiation 454
                    T cell differentiation 324
                      T cell differentiation involved in immune response 87
                        alpha-beta T cell differentiation involved in immune response 79
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 78
                            T-helper cell differentiation 76
                              regulation of T-helper cell differentiation 44
                                positive regulation of T-helper cell differentiation 21
                                  positive regulation of T-helper 1 cell differentiation 5
                                  positive regulation of T-helper 17 cell differentiation + 9
                                  positive regulation of T-helper 2 cell differentiation 7
paths to the root